Search for: "blood flow" - 516 articles found

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News • Based on image-based flow cytometry

Rapid test to predict severe Covid-19 infections

Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…

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Wearable monitoring device

Wireless ultrasound patch monitors vital signs in deep tissues

A team of researchers and scientists from the University of California, San Diego (UCSD) have developed a stick-on ultrasound patch, the first fully integrated wearable system for evaluating cardiovascular function while people walk, run, or even ride a bicycle. This Ultrasonic system-on-patch (USoP) is the result of several years of research conducted by nanoengineering department engineers.

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Article • Supplemental imaging

The next breast screening advancement: Contrast-enhanced mammography

With the recent recommendation changes from the European Council in 2022, how radiologists screen for breast cancer is changing. Mammography has long been an essential technology in screening for breast cancer, and in the recommendations the Council formally recognized the advantages of digital breast tomosynthesis (DBT). This landmark acknowledges the research on and benefits of DBT, advocating…

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Article • Flow cytometry

Detecting and measuring nanoplastics in the blood stream

Plastics are a part of everyday life, and an increasingly concerning factor of global environmental pollution. They also have infiltrated our bodies as microparticles (MPs) and nanoparticles (NPs), found even in placentas supporting foetal life. And they are in our blood. Now, researchers in Spain have developed a new method to detect and measure nanoparticles in human peripheral blood that is…

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Sponsored • Safe blood collection products and value-based care

Protecting patients and healthcare workers

In the last decade, regional and global health organizations have pushed for making safety a central pillar of procurement, with a directive that cost should not be a barrier. The crucial question is: How easy is that to implement? How can a confident decision be reached that protects patients and healthcare workers without straining costs?

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Article • Tissue-engineered glioblastoma model

3D brain tumour in a dish to personalize cancer treatment

It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.

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Article • Imaging biomarkers, AI support and beyond

New tools for Covid-19 assessment

As knowledge about Covid-19 advances, so does the arsenal of techniques to predict, diagnose and follow up on the disease. At ECR, researchers presented a range of promising imaging modalities to keep track of Covid-19 symptoms, severity, and mortality, often including AI support to enhance or accelerate diagnostics.

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Sponsored • DNA extraction chemistry

Providing innovative molecular workflows to empower future diagnostics

Founded in 2018 as a DNA extraction chemistry company, Dutch company MolGen entered the market operating within the agricultural sector. At first, the company’s founders, Maarten de Groot, Wim van Haeringen and Niels Kruize, focused solely on this one industry, mainly developing and marketing advanced bulk chemistry kits for DNA/RNA extraction. These testing products and solutions successfully…

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Article • Pre-, post- and interoperative

Wearable devices in the surgical environment

Wearable technology has become an important part of medicine, from tracking vital signs to disease diagnosis. In surgery, wearable technologies can now assist, augment, and provide a means of patient assessment before, during and after surgical procedures. Wearable technologies are applied before the patient even reaches the operating room, for example in prehabilitation, i.e. pre-treatment…

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News • Blindness prevention

Blue is the clue for diabetic retinopathy risk

Researchers from Tokyo Medical and Dental University (TMDU) demonstrate a thorough and non-invasive imaging technique to identify areas of the eye affected by diabetic retinopathy (DR), a progressive eye disease associated with diabetes and a leading cause of blindness. The researchers have found that blue light can be used to probe the depths of the eye and uncover areas affected by DR.

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News • Coronary microcirculation

New measurements improve diagnosis of ‘woman’s heart’

Researchers at the Catharina Heart and Vascular Center, together with Eindhoven University of Technology, have developed a new measurement method to analyze the smallest capillaries of the heart by measuring blood flow and resistance. The new method to assess coronary microcirculation allows cardiologists to make a clearer diagnosis. Until recently, the tests used for this purpose were not…

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News • Brain stimulation

Infrared light helmet might aid dementia patients

Researchers at Durham University are working on a new infrared light therapy that might have the potential to help people with dementia. In the approach, people wear a specially adapted helmet which delivers infrared light deep into the brain for six-minutes per treatment. This stimulates mitochondria that generate most of the chemical energy needed to power the biochemical reaction in the…

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News • Anemic alternatives

'Bloodless' transfusion could solve global blood shortage

Blood transfusions save lives, yet the precious fluid is in desperately short supply around the globe. But what if transfusions don’t always require blood? A new mathematical model of the body’s interacting physiological and biochemical processes – including blood vessel expansion, blood thickening and flow-rate changes in response to the transfusion of red blood cells – shows that…

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News • Cardiology research

Transcatheter aortic valve replacement: new insights on life expectancy

Researchers at Karolinska Institutet have examined long-term outcomes in patients who received pacemaker implantations after transcatheter aortic valve replacement (TAVR) through their groin. The result showed no significant difference in mortality for the patients with pacemakers compared to those without. The study is published in the journal JACC: Cardiovascular Interventions.

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Article • Molecular targeting for better results

Emerging novel tracers for cardiovascular imaging

Molecular imaging, guided by novel tracers, is emerging as an important diagnostic and therapeutic tool in cardiovascular medicine. Delegates at ICNC-CT, the online International Conference on Nuclear Cardiology and Cardiac CT, also heard that cardiology can learn from fields such as oncology and neurology that have already made important advances in this area. Professor Frank Bengel, who is…

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News • Brain cancer research

Researchers 3D-print entire active tumor

Researchers at Tel Aviv University have 3D-printed a first-of-its-kind glioblastoma tumor that mimics a living cancer malignancy, powering new methods to improve treatment and accelerate the development of new drugs for the most lethal type of brain cancer. Glioblastoma is notoriously fatal as it accounts for the majority of brain tumors and is highly aggressive. The average survival time of…

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News • Hydrogel framework

Synthetic tissue with growing blood vessels developed

Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures. A fundamental requirement for functional tissue is that blood vessels must be able to grow in…

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Video • Automated whole-body reperfusion

New technique to increase survival after cardiac arrest

Researchers at the Medical Faculty of the University of Freiburg have developed an improved therapeutic approach to resuscitate people after cardiac arrest - often without neurological complications. Around 50,000 people suffer sudden cardiac arrest in Germany every year. When occurring outside a hospital, the chances of survival are only ten percent. Survivors often suffer from severe permanent…

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News • Connectome analysis

Machine learning improves prediction of stroke recovery

An international team of scientists led by EPFL has developed a system that combines information from the brain’s connectome – the “wiring” between neurons – and machine learning to assess and predict the outcome of stroke victims. When blood flow to the brain is somehow reduced or restricted, a person can suffer what we know as a stroke (from “ischemic stroke” in medical jargon).…

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News • Preventive potential

Tell-tale signs of heightened stroke risk may appear up to 10 years earlier

The tell-tale signs of a person’s susceptibility to a stroke may appear up to 10 years before the event, suggests research published online in the Journal of Neurology Neurosurgery & Psychiatry. Stroke patients experienced much steeper declines in cognitive abilities and routine daily functioning, starting around a decade before their first stroke, than people who didn’t have a stroke,…

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News • Digital patients, promising results

Are 'virtual' trials the future of research?

A study involving virtual rather than real patients was as effective in evaluating a medical device used  to treat brain aneurysms, according to new research. The findings are proof of concept for what are called in-silico trials, where instead of recruiting people to a real-life clinical trial, researchers build digital simulations of patient groups, loosely akin to the way virtual…

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News • More attempts, worse outcomes

Removing blood clots after stroke: Why the first try counts

After a stroke, doctors can try to remove clots in blood vessels to keep blood flowing freely to the brain. But even though most of these procedures are successful, less than half of people have a successful recovery from the stroke. A new study published in the medical journal Neurology sheds light on why that may be. The study found that trying more than once during a procedure to retrieve a…

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News • Trimodal approach

Combining 3 techniques to boost brain-imaging precision

Researchers report that they have developed a method to combine three brain-imaging techniques to more precisely capture the timing and location of brain responses to a stimulus. Their study is the first to combine the three widely used technologies for simultaneous imaging of brain activity. The work is reported in the journal Human Brain Mapping. The new "trimodal" approach combines…

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News • Abdominal aortic aneurysm

Novel radiotracer shows promise to predict AAA rupture

A new positron emission tomography (PET) radiotracer can detect abdominal aortic aneurysms (AAAs) and potentially predict when they will rupture, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting. Targeting a novel biomarker associated with AAA, the radiotracer is effective both in diagnosis and in providing information to assist in the…

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News • Disease of smallest heart blood vessels

Microvascular angina: the global health problem you've never heard of

For the first time, a prospective, international study has shown that chest pain caused by problems with the very small vessels supplying blood to the heart is an important health problem that increases the risk of heart attacks, stroke and death due to cardiovascular reasons. The study, which is published in the European Heart Journal, recruited 686 patients from 14 institutions in seven…

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News • New cardiology approach

Super saturated oxygen therapy reduces consequences of heart attack

In Germany, more than 200,000 people suffer a heart attack every year. Despite good medical care, many are left with reduced cardiac output. This is particularly true for patients with severe heart attacks: more than 30 percent of those affected develop heart failure, and almost half of them die within the next five years. Experts at the Department of Cardiology and Angiology at Hannover Medical…

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News • Medication testing

'Airway-on-a-chip' to find new Covid-19 drugs

A collaboration spanning four research labs and hundreds of miles has used the organ-on-a-chip (Organ Chip) technology from the Wyss institute at Harvard Univesity to identify the antimalarial drug amodiaquine as a potent inhibitor of infection with SARS-CoV-2, the virus that causes Covid-19. The Organ Chip-based drug testing ecosystem established by the collaboration greatly streamlines the…

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News • The stronger sex after all

Why women may be better equipped to fight Covid-19

When it comes to Covid-19, women seem to be the stronger sex, suffering severe disease at about half the rate as men, but the reason for this has been elusive. Now a chance experiment by an ophthalmology researcher at Duke Health has led to an insight: Women have more of a certain type of immune cell that fights infections in mucosal tissue, and these immune cells amass in the lungs, poised to…

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Harmony Transcatheter Pulmonary Valve (TPV) System

FDA approval for implant to treat congenital heart disease

The U.S. Food and Drug Administration approved the first in the world non-surgical heart valve to treat pediatric and adult patients with a native or surgically-repaired right ventricular outflow tract (RVOT). The device, called the Harmony Transcatheter Pulmonary Valve (TPV) System, is intended to improve blood flow to the lungs in patients with severe pulmonary valve regurgitation without…

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News • Venous cannula system

New circulation implant to bridge the waiting time for donor heart

With the first-in-man implantation of the Berlin Heart Venous Cannula at the LMU University Hospital Munich, Germany, Berlin Heart offers patients with a failing Fontan circulation a unique chance to survive the waiting time for a donor heart. These patients are in a life-threatening condition: their health has deteriorated so much that they desperately need a new heart, but because of their poor…

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News • Gender bias in cardiovascular health

Heart attack: chest pain misdiagnosed more often in women

Chest pain is misdiagnosed in women more frequently than in men, according to research presented at ESC Acute CardioVascular Care 2021, an online scientific congress of the European Society of Cardiology (ESC). The study also found that women with chest pain were more likely than men to wait over 12 hours before seeking medical help. “Our findings suggest a gender gap in the first evaluation of…

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News • Potential for rapid, accurate glycan sequencing

Enormous boost for sequencing key molecules

Using a nanopore, researchers have demonstrated the potential to reduce the time required for sequencing a glycosaminoglycan — a class of long chain-linked sugar molecules as important to our biology as DNA — from years to minutes. Research to be published this week in the Proceedings of the National Academies of Sciences shows that machine-learning and image recognition software could be…

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News • Neuro-map reveals nourishment mechanisms

Food for thought: How our brain keeps its supply up

Our brains are non-stop consumers. A labyrinth of blood vessels, stacked end-to-end comparable in length to the distance from San Diego to Berkeley, ensures a continuous flow of oxygen and sugar to keep our brains functioning at peak levels. But how does this intricate system ensure that more active parts of the brain receive enough nourishment versus less demanding areas? That’s a century-old…

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News • Myocarditis, infarction, ischaemia

Many Covid-19 patients leave hospital with heart damage

Around 50% of patients who have been hospitalised with severe Covid-19 and who show raised levels of a protein called troponin have damage to their hearts. The injury was detected by magnetic resonance imaging (MRI) scans at least a month after discharge, according to new findings published in the European Heart Journal. Damage includes inflammation of the heart muscle (myocarditis), scarring or…

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News • Biological evidence

Scalp cooling protects hair from chemotherapy

A study reveals that scalp cooling physically protects hair follicles from chemotherapy drugs. It is the world’s first piece of biological evidence that explains how scalp cooling actually works and the mechanism behind its protection of the hair follicle. The data was part of an innovative hair follicle research project carried out by the dedicated Scalp Cooling Research Centre based at the…

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News • Alternative therapies

Artificial aorta can reduce patients' blood pressure

Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an ongoing need for alternative therapies. With new developments in cardiac assistance systems, we can delay the need for a transplant – or even eliminate it altogether,” says Professor Yves Perriard, head of EPFL’s…

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News • Promising alternative to heart transplants

'Artificial aorta' to reduce blood pressure

Engineers at EPFL’s Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients’ hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants. “Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an…

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News • Microbiome research

'Organs-on-a-chip' system sheds light on interactions between gut and brain

In many ways, our brain and our digestive tract are deeply connected. Feeling nervous may lead to physical pain in the stomach, while hunger signals from the gut make us feel irritable. Recent studies have even suggested that the bacteria living in our gut can influence some neurological diseases. Modeling these complex interactions in animals such as mice is difficult to do, because their…

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News • Microneedles

No more needles for bloodtests?

Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and…

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News • Aneurysm operations

4D simulation increases safety in brain surgery

Aneurysm operations in the brain rank among the most delicate procedures in neurosurgery. The highest demands are placed on surgeons when choosing the type of intervention, planning the route and carrying out extremely delicate procedures on the blood vessel. A new training technology co-developed between Inselspital, Bern University Hospital, and ARTORG Center of the University of Bern, will…

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News • Promising drug combination

Stroke: new prescription strategy shows great potential

Research conducted at the Health New Orleans Neuroscience Center of Excellence at the Louisiana State University (LSU) reports that a combination of an LSU Health-patented drug and selected DHA derivatives is more effective in protecting brain cells and increasing recovery after stroke than a single drug. The findings are published in Brain Circulation.

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Article • Preventing endoscope contamination

Ways to enhance hygiene in endoscopy

Stringent endoscope cleaning between procedures is vital. However, with so many steps in the process – plus high demand for rapid turnaround of endoscopes – contamination and biofilm build-up are still being reported. Endoscope hygiene and cleaning protocols were central to an online event organised by Pentax Medical, with important contributions from leading specialists. The event examined…

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News • Digital health

AI test rules out Covid-19 diagnosis within one hour

An Artificial Intelligence test has been shown to be able to rapidly screen patients arriving in Emergency Departments for Covid-19, using clinical information routinely available within the first hour of coming to hospital. Results of the CURIAL study, published in The Lancet Digital Health, show that the AI test correctly predicted the Covid-19 status of 92.3% of patients coming to Emergency…

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Article • A technique evolves

Cardiac CT: a diagnostic jack-of-all-trades

According to Professor Fabian Bamberg, Medical Director at the Clinic for Diagnostic and Interventional Radiology at University Hospital Freiburg, Germany, ‘In recent years, cardiac CT has seen a mindboggling technological evolution.’ It is, he believes, a very robust procedure that allows the routine acquisition of high-resolution images with very few side effects.

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News • White matter hyperintensities

High blood pressure puts the brain at risk

Higher than normal blood pressure is linked to more extensive brain damage in the elderly, according to a new study published in the European Heart Journal. In particular, the study found that there was a strong association between diastolic blood pressure (the blood pressure between heart beats) before the age of 50 and brain damage in later life, even if the diastolic blood pressure was within…

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Sponsored • Respiratory diseases

Breathing life into patient care

As a world leading manufacturer of medical devices, the subclassification of Contec Medical products includes numerous series for multi-parameter monitoring, ECG, oximeter, blood pressure, telemedicine health, respiratory sleep, and more. With the frequently increasing occurrence of respiratory diseases, Contec Medical reports on its great efforts in the research and development of related…

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News • False positive results

Accuracy of rapid covid test may be lower than previously suggested

The accuracy of a rapid finger-prick antibody test for SARS-CoV-2, the virus responsible for covid-19 infection, may be considerably lower than previously suggested, finds a study published by The BMJ. The results suggest that if 10% of people given the test had previously been infected, around 1 in 5 positive test results would be incorrect (false positive results). These conclusions contrast…

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Interview • Quality aspects

Lab automation – economic aspects and Covid-19

The academic teaching Karlsruhe Hospital, at the University of Freiburg, is the largest hospital providing tertiary care in the Middle Upper Rhine Valley. Every year, 63,000 in-patients and 180,000 out-patients are treated in the 1,500-bed facility with 50 departments and 30 out-patient clinics. Inevitably, a hospital of this size has a central lab. We spoke with Dr Horst Mayer, managing senior…

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News • POCT for the head

New device detects traumatic brain injury 'on the spot'

A method for detecting traumatic brain injury at the point of care has been developed by scientists at the University of Birmingham. Using chemical biomarkers released by the brain immediately after a head injury occurs, researchers are able to pinpoint when patients need urgent medical attention. This saves time in delivering vital treatment and avoids patients undergoing unnecessary tests where…

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News • Promising approach for eye diseases

Functional human retinas created in a dish

Scientists have generated accurate replications of human retinas in culture that can be used to pinpoint the specific types of cells affected by genetic eye diseases. The culmination of a six-year effort, this achievement will accelerate progress in developing new therapies and was reported in Cell by a team led by Botond Roska at the Institute for Molecular and Clinical Ophthalmology Basel (IOB)…

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Article • Entering a new age

AI predicts blood flow to the heart

Artificial Intelligence (AI) has, for the first time, measured blood flow to the heart to help predict which patients may suffer myocardial infarction or stroke. A research team at University College London and Barts Health NHS Trust and the National Institutes for Health (NIH) in the USA – are optimistic that AI analysis of perfusion maps will be a reliable, convenient and detailed new…

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Article • Blood poisoning

Exploring the importance and challenges of early sepsis diagnosis

On the occasion of this year's World Sepsis Day, we spoke with Elena Sukhacheva, Ph.D., director of medical and scientific affairs at Beckman Coulter, about the status quo and outlook on sepsis diagnostics. With the severity of sepsis symptoms, it’s easy to comprehend why it is invaluable to diagnose this disease properly and in a timely manner. Dr Sukhacheva takes an in-depth look at…

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News • Joint Research

AI helps diagnosing Covid-19

Fujitsu and Tokyo Shinagawa Hospital today announced the launch of a joint R&D project for AI technology to support diagnostic imaging via chest CT (Computed Tomography), which represents a promising candidate for the effective diagnosis of COVID-19 pneumonia.

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Video • Phlebotomy equipment

Vacuette® Visio Plus Needle

The Vacuette® Visio Plus Needle with optical venipuncture control can make an important contribution to simplifying blood collection routine for phlebotomists. The needle has a translucent plastic hub, which functions as a view window. If venipuncture is successful, the view window is coloured red due to the blood flow. The Vacuette Visio Plus Needle guarantees a safe blood collection procedure…

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News • Expanding image-guided therapy devices portfolio

Philips to acquire Intact Vascular

Royal Philips announced that it has signed an agreement to acquire Intact Vascular, Inc., a U.S.-based developer of medical devices for minimally-invasive peripheral vascular procedures. Intact Vascular will enhance Philips’ image-guided therapy portfolio, combining Philips’ interventional imaging platform and diagnostic and therapeutic devices with Intact Vascular’s unique, specialized…

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News • Facial photo analysis

AI uses ‘selfies’ to detect heart disease

Sending a “selfie” to the doctor could be a cheap and simple way of detecting heart disease, according to the authors of a new study. The study is the first to show that it’s possible to use a deep learning computer algorithm to detect coronary artery disease (CAD) by analysing four photographs of a person’s face. Although the algorithm needs to be developed further and tested in larger…

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Article • Rapidly meeting a surging demand

The science behind 3-D printed nasal swabs

Medical device approved 3-D printers are producing clinically safe and effective nasopharyngeal swabs for COVID-19 testing. A nasal swab may seem rudimentary, but is essential for testing COVID-19. Diagnostic test kits and components – nasal swabs, collection vials, and chemical reagents – have been in short supply worldwide, especially in March. Ironically, nasopharyngeal swabs are…

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Video • Improving first aid

New 3D CT scanning method shows what happens during CPR

Rapid first aid during cardiac arrest makes the difference between life and death. But what happens to the heart and the internal organs when people come running and begin to give well-meaning but heavy-handed heart massage as they attempt to keep the person who has suffered a cardiac arrest alive? A research collaboration between the Department of Forensic Medicine at Aarhus University and the…

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News • Smart breathing support

Self-learning ventilators could save more COVID-19 patients

As the corona pandemic continues, mechanical ventilators are vital for the survival of COVID-19 patients who cannot breathe on their own. One of the major challenges is tracking and controlling the pressure of the ventilators, to ensure patients get exactly the amount of air they need. Researchers at the Eindhoven University of Technology (TU/e) have developed a technique based on self-learning…

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News • L-type calcium channel blockers

LCCBs may contribute to heart failure

L-type calcium channel blockers (LCCBs) — the most widely used drugs for treating hypertension — may harm the heart as much as help it, according to a new study. The research team, led by the Pennsylvania State University, found that in rats and human cells in vitro, LCCBs cause changes in blood vessels — known as vascular remodeling — that reduce blood flow and increase pressure.…

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News • Oncology

How cancer spreads in blood

A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these vesicles might be used to diagnose cancer in the future, avoiding the need for invasive surgical biopsies.

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News • Antithrombotic approach

A new way to detect blood clots

Biomedical engineering researchers at Texas A&M University designed a medical device that mimics blood vessels to design and monitor drugs for patients with clotting disorders. This approach could be especially beneficial for pediatric patients. Unlike what a biology textbook may show, blood vessels are not straight cylinders. They are tortuous, meaning they have complex curves, spirals and…

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News • Robotic innovation

Micro robot rolls deep into the body

A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell travelling through the circulatory system. It has the shape, the size and the moving capabilities of leukocytes and could perhaps be well on its way – in a rolling motion of course – to revolutionize the minimally invasive treatment of…

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News • Improved grip and comfort

New cap design for capillary blood collection tubes

The MiniCollect Capillary Blood Collection System launched by Greiner Bio-One in 2016, has an improved cap on all its blood collection tubes. The new version, designed for easier opening, has an increased number of ridges that are also deeper to improve grip and user comfort. The cap rim also overlaps the top of the tube to augment grip and ease opening. The capillary blood collection tubes offer…

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Sponsored • Percutaneous coronary intervention (PCI)

Robotic angioplasty: The future of endovascular interventions

An exciting development from an innovative French company is poised for a major breakthrough in European markets. As is now well-known, coronary angioplasty is a procedure that widens and/or unblocks the arteries to the heart by the insertion and inflation of a balloon and/or stent into the vessel lumen. In modern practice, a stent is normally left in place to ensure the blood flow remains…

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News • Non-alcoholic fatty liver disease

3D model of human liver tissue for better NAFLD diagnosis

Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of NAFLD. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural…

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News • Venous thromboembolism (VTE)

Award for new blood clot prevention technology

A partnership between the Royal Stoke University Hospital, part of the University Hospitals of North Midlands NHS Trust, and a UK industry-leading medical devices company have been rewarded for its use of an innovative bioelectronic technology to prevent life-threatening blood clots in acute stroke patients – winning in the category: Best use of technology (acute care), at the Building Better…

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News • Rehabilitation

Hope for patients in vegetative and minimally conscious states

Non-invasive brain stimulation is to be trialed for the first time alongside advanced brain imaging techniques in patients who are minimally conscious or in a vegetative state. The study builds on promising results from the Centre for Human Brain Health at the University of Birmingham which suggested that non-invasive brain stimulation can improve the success of rehabilitation for non-responsive…

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News • Open surgery or TAVI?

New ways to treat severe aortic stenosis

New research at the University of Leicester, funded by the British Heart Foundation (BHF), could change the way people living with a debilitating heart condition are treated. The £2.7m clinical trial aims to identify the best time to operate on people living with severe aortic stenosis (AS). AS is a common condition that causes a narrowing of the heart valve, restricting blood flow out of the…

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Video • Tissue construct

A 'swift' way to 3D-print organs

Twenty people die every day waiting for an organ transplant in the U.S., and while more than 30,000 patients now receive transplants annually, another 113,000 are currently on organ waitlists. Many people see artificially grown human organs as the Holy Grail for resolving the organ shortage, and advances in 3D printing have led to a boom in using that technique to build living tissue constructs…

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News • Reopening blood vessels

Microbubbles and ultrasound can help treat heart attacks

Doctors are using microbubbles and ultrasound to treat heart attacks – deploying these traditional diagnostic tools in an attempt to reopen tiny blood vessels, reduce scar size and restore heart function, according to a study described at a medical conference in Chicago. “This study shows for the first time that microbubbles can be used to both diagnose and treat small vessel obstructions…

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News • The XX factor

XX chromosomes put women's hearts at risk

New research at the University of Kentucky has confirmed that the presence of XX sex chromosomes increases the amount of fat circulating in the blood, which leads to narrowing of the arteries and ultimately a higher risk of heart attacks and coronary artery disease. The research was published in Nature Communications. The leading cause of death in women is coronary artery disease (CAD), but women…

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Sponsored • POCUS

Point-of-care ultrasound – a valuable tool for nephrology

Point-of-care ultrasound (POCUS) systems are becoming a common sight in nephrology departments and renal dialysis clinics, helping clinical staff to evaluate and effectively access the vasculature of dialysis patients. Dr Jean-Yves Bosc, a nephrologist and vascular doctor working at the non-profit private health establishment AIDER SANTÉ in the South of France, has been a champion of ultrasound…

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Article • High tissue contrast, spatial detail, complete tissue characterisation

MRI shows cardiac diagnostic value

Cardiovascular magnetic resonance (CMR) imaging has become faster, simpler and more widely available in recent years because it has evolved to deliver effective assessment and diagnosis of a range of heart conditions with expanding guideline indications.

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News • Vascular PSP survey

Giving patients a say in vascular conditions research

A new survey will give patients, carers and members of the public the opportunity to have their say in what they think is important for future research for vascular conditions. The Vascular Priority Setting Partnership (PSP) survey, developed in partnership with the James Lind Alliance aims to identify unanswered questions about the prevention, diagnosis and treatment of vascular conditions from…

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News • Tissue model

How clots become firm in the presence of blood flow

Blood clotting is one of the most critical, protective processes in human physiology. When something goes wrong with clotting, either because there is too much clotting, leading to a stroke, or not enough, leading to internal bleeding, the outcome can be catastrophic. Now, University at Buffalo researchers have established an in vitro model of this process that will help clinicians improve…

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Article • Surface-enhanced Raman spectroscopy

The lab-on-a-chip SERS platform

Analytically sensitive and specific detection of pharmaceuticals or metabolites in bodily fluids, as well as fast and reliable detection of human pathogens, are major challenges for instrument-based analytics in medical diagnostics. Over the past few years the combination of surface-enhanced Raman spectroscopy (SERS) and microfluidic devices (Lab-on-a-Chip) has emerged as a perfectly suited…

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Video • Tailor-made

Artificial heart valves from silicone

Scientists at ETH Zürich and the South African company Strait Access Technologies are using 3D printing to produce custom-made artificial heart valves from silicone. This could help meet an ageing population’s growing demand for replacement heart valves. The human heart has four chambers, each equipped with a valve to ensure blood flow in one direction only. If any of the heart valves are…

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Video • Miniscule swimmers

Microrobots could re-shape drug delivery

Scientists have developed minute flexible robots that could help revolutionise drug delivery in the future. These ‘microrobots’ are so small that they could be ingested, or inserted into human veins to deliver drug therapies directly to diseased body areas.

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Sponsored • Sysmex

With the UN-Series, the choice is yours

Using urine to obtain diagnostic insights has been done for thousands of years and still remains an important tool to obtain crucial information. Covering a range of tests, urinalysis may be used to screen for or help to diagnose ailments such as urinary tract infections, kidney disorders, liver problems, diabetes or other medical conditions, just to name a few. Because urinalysis has been around…

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Sponsored • Hematology

Early sepsis indicator helps identifying patients at risk

The critical element of testing for sepsis lies not so much in the location but in the timing and rapidity of results, according to Professor Jeannine T. Holden from Beckman Coulter Early identification enables treatment protocols to be delivered more quickly, offering better patient outcomes. Those most at risk, suggests Holden, are not patients within the intensive care unit – who are already…

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Article • Flow cytometry

Living cells – the essential biomarker

The team of the Heinz Nixdorf Chair of Biomedical Electronics at the Technical University of Munich focuses on innovative diagnostic tools to accelerate the development towards personalized medicine. Therapies tailored to the individual patient – this is the future not only of oncology but of many medical disciplines. “At this point, however,” concedes Professor Dr Oliver Hayden,…

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News • Be prepared

This 3D printed baby dummy could improve resuscitation training

Two millions: this is, worldwide, the number of babies which suffer suffocation during birth every year. A resuscitation procedure is sometimes the key to avert irreparable damages for the baby. And, for successful outcomes, promptness of action and preparation are vital. Researcher Mark Thielen (Industrial Design) from the Eindhoven University of Technology (TU/e) developed a 3D printed baby…

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News • Flow cytometry lab

New ClearLLab IVD Reagents launched

Beckman Coulter is launching the ClearLLab 10C System for the clinical flow cytometry lab. The new system is the first 10-color IVD panel of immunophenotyping reagents cleared by the Food and Drug Administration (FDA) for both lymphoid and myeloid lineages. The four dry pre-mixed antibody tubes use the company’s DURA Innovations technology, eliminating the need to pipette antibodies, improving…

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News • Research

Promising new stroke therapy in development

Researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have developed a novel stroke therapy that, when tested in mice and dogs, has proven superior to the standard of care therapy now offered to patients suffering a stroke. Findings of the study are published online in Molecular Therapy. “We have shown that our drug, which is completely…

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News • Alternative to statin treatment

Atherosclerosis: Antibodies stabilise plaque

Researchers at Karolinska Institutet have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilise the plaque that accumulates on the artery walls, which reduces the risk of it rupturing and causing a blood clot. It is hoped that the results, which are published in the journal Circulation, will eventually lead to improved…

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News • Healthy heart

How the 'blue' in blueberries can lower blood pressure

A new study published in the Journal of Gerontology Series A has found that eating blueberries can lead to an improvement in blood vessel function and a decrease in systolic blood pressure. Researchers from King’s College London and the University of Surrey studied 40 healthy volunteers for one month. They were randomly given either a drink containing 200g of blueberries, or a matched control…

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News • Preserving your eyesight

7 ways to prevent macular degeneration

Doctors aren’t sure what causes age-related macular degeneration, a disease that affects millions of people in the United States. Also called AMD, it is known for causing blurred central vision due to damage to the macula — a small area at the back of the eye. Currently, there is no cure. But there are known risk factors that eye care professionals often use to help determine a patient’s…

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News • Cardiology & calcium

First look at the ‘molecular switch’ that makes our heart beat

Oxford University Radcliffe Department of Medicine researchers have developed a new method that uses a protein originally found in marine corals to visualise the flow of calcium that makes the heart beat. In a paper published in the journal Circulation Research, they used this technique to uncover the effects of genetic errors that contribute to a heart condition that is the leading killer of…

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News • Tiny threat

Nanoparticles may promote cancer metastasis

Nanoparticles can be found in processed food (e.g. food additives), consumer products (e.g. sunscreen) and even in medicine. While these tiny particles could have large untapped potential and novel new applications, they may have unintended and harmful side effects, according to a recent study by researchers from the National University of Singapore (NUS). Specifically, NUS researchers found that…

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News • Diagnostics

Heat it and read it

You’re sweating and feverish and have no idea why. Fortunately, Sandia National Laboratories scientists have built a device that can pinpoint what’s wrong in less than an hour. Unlike most medical diagnostic devices which can perform only one type of test — either protein or nucleic acid tests — Sandia’s SpinDx can now perform both. This allows it to identify nearly any cause of…

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News • Blockage detection

This blood flow sensor wraps around the blood vessel

A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor, detailed in a paper published in Nature Biomedical Engineering, monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if…

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News • On the go

Wearable ultrasound patch penetrates the skin to measure blood pressure

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) are literally breaking barriers using ultrasound waves emitted from a flexible patch to accurately measure central blood pressure and help detect cardiovascular problems earlier. For a while now, smart, wearable devices have had the ability to capture how many steps we take in a day or measure our heart…

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News • Neuropathy

How to protect your feet from diabetes

Diabetes is a disease that can cause a host of accompanying problems, for example nerve dysfunction that can lead to diabetic feet. John Giurini, DPM, Chief of Podiatric Surgery at Beth Israel Deaconess Medical Center, talks about where these complications come from and what can be done to deal with them.

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Article • Evolving technique

Flow cytometry rises to new challenges

Flow cytometry has proved an invaluable diagnostic tool for leukaemia and lymphoma for almost three decades. Now, however, this is evolving in applications to seek out residual disease in cases and in fusion with molecular testing to advance its diagnostic potential. However, although recognised as fast, flexible and accurate, flow cytometry suffers from a lack of standardisation, according to…

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Article • Digital PET imaging

Digital Photon Counting improves diagnostic accuracy

Built as the first commercially available scanner to deliver truly digital PET, the Vereos PET/CT, from Philips, offers revolutionary Digital Photon Counting technology. The science behind this scanner evolution is ‘quite complicated’, agrees Piotr Maniawski, Director of Clinical Science Nuclear Medicine at Philips Healthcare, yet the improved performance is significant, particularly when…

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Article • CEUS & the kidneys

Contrast-enhanced ultrasound for renal masses

Contrast enhanced ultrasound (CEUS) has proved in trials to be more accurate than computed tomography and MRI and can help eliminate the need for unnecessary biopsies and surgery. Dr Richard Barr, Professor of Radiology at Northeast Ohio Medical University, explains the benefits of the modality.

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Sponsored • Cardio app

AI system screens early Phase AFib

Here at Medica, the Taiwanese start-up Maisense is demonstrating Freescan, its artificial intelligence (AI) based solution to screen for stroke through the early detection of atrial fibrillation (AFib). Speaking of the system’s aims, Maisense summed up this huge health problem. ‘Every four minutes, someone dies of stroke. Thirteen percent of these are classified as haemorrhagic stroke. When…

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Sponsored • Point-of-care

Improving the safety and quality of pediatric emergency care with POC ultrasound

Point-of-care ultrasound (POCUS) has become an important adjunct to clinical diagnosis and procedural guidance in the Pediatric Emergency Department (PED), supported by literature demonstrating that its use can improve patient safety and expedite life-saving care. POCUS further helps to reduce costs and children’s exposure to ionizing radiation. Not only is POCUS ideally suited for…

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News • Innovation award

Multi-organ "lab-on-a-chip" to reduce animal testing

To simulate the blood circulation and the organs of animals or humans, engineers from Fraunhofer in Dresden have developed a so-called "multi-organ chip". This microsystem from the Fraunhofer Institute for Material and Beam Technology IWS Dresden has now received an "EARTO Innovation Award" in Brussels. The "lab-on-a-chip" will help industry to develop new drugs and…

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Sponsored • Innovation

Hematology: Advancements and future trends

While the role of the laboratory in disease diagnosis and management has expanded in recent years, causing an overwhelming rise in testing demands, the availability of skilled technologists and specialists has been diminishing. To meet the needs of an overworked and increasingly generalized workforce, today’s products not only must deliver more clinical data than ever before, but also must be…

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Sponsored • Blood flow imaging

A new tool box enhances heart failure diagnosis

One of the challenges for every echocardiography lab is the technically difficult patient. Conventionally, labs use contrast agents to enhance endocardial border visualization. The application of contrast agents increases the exam time, resources and costs. Additionally, the use of contrast turns a previously non-invasive exam into an invasive procedure. Hitachi Healthcare has now developed a…

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News • Cerebrovascular disease

Stroke deaths decrease all over Europe – but it's too early to cheer

New research, published in the European Heart Journal, has shown deaths from conditions that affect the blood supply to the brain, such as stroke, are declining overall in Europe but that in some countries the decline is levelling off or death rates are even increasing. Cerebrovascular disease includes strokes, mini-strokes, and narrowing, blockage or rupturing of the blood vessels supplying…

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News • Patient safety

Greiner Bio-One expands blood collection product range

The Vacuette Safety Winged Set is a new addition to Greiner Bio-One’s (GBO) range of safety products. GBO now offers its customers an even wider selection of safety blood collection sets. In response to high demand for Greiner Bio-One safety products, the existing range will be joined by the new Vacuette Safety Winged Set. As always, the aim is to provide functional, user-friendly and…

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News • Gas embolotherapy

Blowing bubbles for cancer treatment

Recently, scientists have explored another version of embolization, called gas embolotherapy. During this process, the blood supply is cut off using acoustic droplet vaporization (ADV), which uses microscopic gas bubbles induced by exposure to ultrasonic waves. A team of researchers from China and France has discovered that these bubbles could also be used as potential drug delivery systems.

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Video • Medical technology

Genrui presents latest products

Genrui Biotech Inc., one of the leading Chinese developers and manufacturers of IVD equipment and reagents, present their latest POCT devices at the China International Medical Equipment Fair (CMEF). Among the presented devices are the 5-Part Auto Hematology Analyzer KT-6610, which uses advanced tri-angle laser scattering, flow cytometry technology to deliver white blood cell differential…

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News • Astrozytes

The brain’s “rising stars”: New options against Alzheimer’s?

A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a novel potential approach against Alzheimer’s disease. In studies in mice, the researchers were able to show that blocking a particular receptor located on astrocytes normalized brain function and improved memory performance. Astrocytes are star-shaped, non-neuronal cells involved in the regulation of…

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News • Heat therapy

Soaking in a hot tub has unexpected benefits, researchers find

According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…

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News • Equipment

A tiny, more cost-effective white blood cell counter might be available soon

A thin copper wire wrapped around a channel slightly thicker than a strand of hair could be the key to manufacturing a compact electronic device capable of counting white blood cells from the comfort of one’s home, a Kennesaw State University researcher says. Hoseon Lee, an assistant professor of electrical engineering in the Southern Polytechnic College of Engineering and Engineering…

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Article • Value based lab medicine

Meeting the challenge of modern laboratory demands

Faced with the constant challenge of increasing demand and a backdrop of falling reimbursement, Mayo Clinic in the United States has adopted an innovative and proactive approach to managing its laboratory services. That has seen the US-based medical giant embrace a variety of tools and reference materials to aid clinician decision making, improve care and lower costs. Dr Curt Hanson, Chief…

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News • Early dementia diagnosis

Brain imaging provides clues about memory loss

University of California, Irvine-led researchers, however, have found that high-resolution functional magnetic resonance imaging of the brain can be used to show some of the underlying causes of differences in memory proficiency between older and younger adults. The study involved 20 young adults (ages 18 to 31) and 20 cognitively healthy older adults (ages 64 to 89). In the study, the…

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Article • Automation

Mass spectrometry is advancing laboratory practice

Mass spectrometry is moving laboratory medicine to increasingly automated discrete analysis methods, resulting in ever faster and more reliable results. It is also leveraging economies of scale as an increasingly cost-effective tool, says Craig Webster, Consultant Clinical Scientist and Clinical Lead, Department of Biochemistry and Immunology at Heartlands Hospital in Birmingham. Speaking about…

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Sponsored • Artificial lungs

Easing ARDS and AECOPD

Innovative ‘artificial lungs’, which help the patients to breathe, offer less traumatic treatment for severe diseases such as acute respiratory distress syndrome (ARDS) or chronic obstructive pulmonary disease (COPD/AECOPD). Respiratory failure is one of the most frequent causes of ICU admission. It may occur inter alia in patients with ARDS, a dangerous condition when the respiratory system…

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Article • Celesteion PET-CT

Making a difference with Dual Modality Imaging

The Clinica Creu Blanca Diagnostic Group in Barcelona, Spain, is the first clinic in Europe to use Canon Medical System’s new Celesteion PET-CT Scanner. Dr. Xavier Alomar, Head of the Diagnostic Imaging Department at the Clinic, explains how the new system has opened up a large field of diagnostic possibilities for the Group in Metabolic Medicine in Oncology, Neurology, Cardio­logy and…

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News • A map to the heart

The meaning of heart geometry in surgery

Geometry is often referenced for matters of the heart. Marriage has been described as “two parallel lines,” and others have compared love to an “irrational equation” or as unending as “pi.” But when it comes to the medical matters of the heart, geometry can be a lonely and dangerous affair. “The shape and size of a heart is not the same for every person, and a diseased heart, such…

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News • Responsive or not?

Breast cancer: Near-infrared light shows chemo beneficiaries

A new optical imaging system developed at Columbia University uses red and near-infrared light to identify breast cancer patients who will respond to chemotherapy. The imaging system may be able to predict response to chemotherapy as early as two weeks after beginning treatment. Findings from a first pilot study of the new imaging system—a noninvasive method of measuring blood flow dynamics in…

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Video • TCAR (Transcarotid artery revascularization)

Reversing blood flow reduces stroke risk during carotid artery procedure

Loyola Medicine is the first academic medical center in Illinois to use the TCAR system, which reduces stroke risk during carotid artery procedures by temporarily reversing blood flow. Carotid arteries on each side of the neck supply blood to the brain. In patients with carotid artery disease, a build-up of plaque can cause blockages. A common method to open the artery involves a balloon…

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News • Hypoplastic left heart syndrome (HLHS)

Stem cells might be the key to treating rare cardiac defect

Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart. The Phase I study is part of a multi-center collaboration dedicated to employing innovative therapies to improve outcomes for children…

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News • No more stitches

This surgical glue could transform surgeries and save lives

Sutures and staples are the traditional methods for closing surgical incisions and wounds in emergency situations. However, these methods can be inadequate in complex surgeries and cannot make an air-tight or liquid-tight seal on a lung or artery wound or incision. Now researchers funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have created a surgical glue that…

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News • Ophthalmology

Researchers explore way to reverse diabetic blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments that suppressed vascular endothelial growth factor (VEGF) in the eye, researchers were able to re-establish normal blood…

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News • Ventricular tachycardia

Deadly heart rhythm halted by noninvasive radiation therapy

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients who had irregular heart rhythms, called ventricular tachycardia, at the School of Medicine. The patients…

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News • Prognosis and diagnosis

Deep insight into the heart

By no means are only elderly people at risk from heart diseases. Physically active individuals can also be affected, for example if a seemingly harmless flu bug spreads to the heart muscle. Should this remain undetected and if, for example, a builder continues with his strenuous job or an athlete carries on training, this can lead to chronic inflammation and in the worst case even to sudden…

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News • De-fragmenting efforts

Coordinated emergency care improves heart attack survival

Coordinating the response to heart attacks among emergency responders and hospitals reduces the time to treatment and saves lives - even on a large, regional scale, according to a study led by the Duke Clinical Research Institute with support from the American Heart Association. In the largest demonstration of the coordinated approach - 132 hospitals and 946 EMS agencies in 12 U.S. regions -…

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News • Cooperation

GE and NVIDIA join forces to accelerate AI adoption in healthcare

GE Healthcare and NVIDIA announced they will deepen their 10-year partnership to bring the most sophisticated artificial intelligence (AI) to GE Healthcare’s 500,000 imaging devices globally and accelerate the speed at which healthcare data can be processed. The scope of the partnership, detailed at the 103rd annual meeting of the Radiological Society of North America (RSNA), includes the…

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Article • Local and elegant

Extending life with TIPS and TACE

Liver disease is widespread in Germany. It is, in fact, the most common cause of death in patients under the age of 40, with liver cirrhosis, which can develop into liver cancer, playing a major role here. These days, modern, comprehensive treatment concepts are unimaginable without interventional radiology, for liver cirrhosis as well as liver cancer. Prof. Dr. Christian Stroszczynski, Director…

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Article • CEUS

Advancing contrast enhanced ultrasound

The ability to demonstrate blood perfusion as well as organ function using contrast agentenhanced ultrasound is quickly finding innovative uses in clinical practice. Contrast-enhanced ultrasound (CEUS) has advanced rapidly since its first introduction. Today it is widely used as a primary imaging technique for a number of indications and pathologies. At a symposium organised by Bracco Imaging…

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News • Innovation

Samsung introduces new premium ultrasonic diagnosis device 'RS85'

Samsung Medison, a global medical equipment company and an affiliate of Samsung Electronics, introduced the RS85, a new premium ultrasonic diagnosis device that provides enhanced image quality, usability, and convenience for medical and radiology professionals. “We are pleased to launch the RS85, a new premium medical device with superior image quality and usability based on Samsung’s…

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Sponsored • BeneVision Patient Monitoring Solution

Envisioning the future of patient monitoring

30 years ago, monitoring in most intensive care environments was via an ECG display with a numeric value for heart rate combined with intermittent manual measurements of blood pressure. Advances in technology have greatly increased monitoring parameters. Eight, for example, are included in the current minimum standards for monitoring under anaesthesia but more than ten further sensors are…

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Article • Automation, AI and more

Abundant ultrasound tech potential

Automation continues to conquer healthcare, including diagnostic imaging. Christian Kollmann, Assistant Professor at the Centre for Medical Physics and Biomedical Technology, Medical University Vienna, Austria, highlights innovative software, fast hardware and artificial intelligence in ultrasound – today and in the future. Automated analyses are already supporting the diagnostic work-up. In…

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News • Study

Mapping brain connectivity with MRI may predict cardiac arrest survival

A new study led by Johns Hopkins researchers found that measures of connectivity within specific cerebral networks were strongly linked to long-term functional outcomes in patients who had suffered severe brain injury following a cardiac arrest. A description of the findings, published in October in the journal Radiology, suggests that mapping and measuring such connectivity may result in highly…

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Sponsored • Point-of-care ultrasound

Gambian trip offers dialysis hope

Point-of-care ultrasound is a valuable tool for successful dialysis fistula surgery, allowing pre-operative mapping to find a suitable site and post-operative fistula scanning to check for stenosis and adequate blood flow. Anna Jerram, a clinical vascular scientist at the Manchester Royal Infirmary, discusses the role POC ultrasound played during a recent trip to the Gambia to provide critical…

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Sponsored • Advertorial

Best practice: Xenios hand in hand with hospitals

Central alarm management of the Xenios console via the Philipps IntelliVue MX800® patient monitoring system. Achieving the goal in an easy and efficient manner by a combination of safety and innovation. The Barmherzige Brüder hospital in Regensburg and Xenios combine both in the clinical practice.

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News • Study

How to decrease the discard rate of donated organs

A new study indicates that many donated organs that are discarded might be suitable for transplantation if certain steps are taken to limit damage following donation. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN). In most cases in the United States, transplant organs come from donors following brain death, in which all the functions of the…

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News • Cardiac injury

Could this be the way to mend a broken heart?

Early research results suggest scientists might be on to a way to preserve heart function after heart attacks or for people with inherited heart defects called congenital cardiomyopathies. Researchers at the Cincinnati Children’s Heart Institute report in Nature Communications that after simulating heart injury in laboratory mouse models, they stopped or slowed cardiac fibrosis, organ…

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Sponsored • Transducer

The multi-tasking 4G CMUT linear matrix probe

Holding Hitachi’s newest ultrasound probe in your hand, it looks and feels like any other ultrasound transducer. ‘Yet, you are actually holding a marvel of ultrasound engineering, a true break-through in transducer architecture that performs so well across so many types of exams that you may never want to let it go,’ the manufacturer reports.

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Article • Achieving a faster workflow

A modular approach to urinalysis

The reasons why doctors request urinary analysis are varied – perhaps to detect a possible or suspected infection, or to screen for kidney diseases. In all cases a reliable and rapid result is the major aim. Urinary microscopy and culture have been the mainstays of urinary analysis for many, many years both of which require time and specialist handling.

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News • Blood flow control

"Switch" in brain’s capillary network monitors activity

All it takes is the flip of a protein “switch” within the tiny wire-like capillaries of the brain to increase the blood flow that ensures optimal brain function. New research has uncovered that capillaries have the capacity to both sense brain activity and generate an electrical vasodilatory signal to evoke blood flow and direct nutrients to nourish hard-working neurons.

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Article • Monitoring

Down to earth devices

Space missions are famous for driving innovation, from Mylar blankets to microchips. So when French scientists learned one of their compatriots would be aboard the Soyuz MS-03 spacecraft to reach the International Space Station (ISS), they gathered cutting edge technologies for him to carry into orbit.

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News • Healthy Eating

Study Finds Association Between Eating Hot Peppers and Decreased Mortality

Like spicy food? If so, you might live longer, say researchers at the Larner College of Medicine at the University of Vermont, who found that consumption of hot red chili peppers is associated with a 13 percent reduction in total mortality – primarily in deaths due to heart disease or stroke – in a large prospective study. The study was published recently in PLoS ONE.

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News • Artificial beta cells

New weapon against Diabetes

ETH Researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.

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Article • Xenon MRT

A revolution in lung function diagnostics

Since lung diseases tend to be complex, imaging is a crucial diagnostic tool. While computed tomography has become the standard modality, which is frequently used outside hospital settings, specialised MRI diagnostics remains the preserve of large university medical centres.

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Spanish hospital checks vital signs remotely

Not having to visit hospital daily, or stay there too long, can improve the lives of patients tremendously. The Vic Hospital Consortium, in Catalonia, Spain, has begun to use a new remote monitoring system that enables it to monitor patients wherever they are. European Hospital spoke with Enrique de la Vega, digital product manager at Catalonia’s technology centre Eurecat, the organisation…

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Article • Contrast enhancement

Sonic boom with bubbles

Illuminating blood vessels, opening the blood-brain barrier and delivering drugs. What will be the next big thing that tiny microbubbles can do?

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News • Pediatrics

Technology reveals fetal brain activity

NIBIB-funded researchers at the University of Washington have pioneered an approach to image functional activity in the brains of individual fetuses, allowing a better look at how functional networks within the brain develop. The work addresses a common problem of functional MRI; if the subject moves during the scanning, the images get distorted.

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Article • Future changes

Laboratory medicine is an interdisciplinary subject

‘Lab medicine connects’ is the congress theme of the German Congress of Laboratory Medicine and reflects the fact that laboratory medicine is an interdisciplinary subject like no other and connects those who are involved in medicine across disciplines. It works almost imperceptibly in the background, hardly noticed by patients. European Hospital spoke with this year’s Congress President,…

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News • Oncology

Nanovaccine could enhance cancer immunotherapy

NIBIB researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects. The nanovaccine helps to efficiently deliver a unique DNA sequence to immune cells – a sequence derived from bacterial DNA and used to trigger an immune reaction. The nanovaccine also protects the DNA from being destroyed inside the body, where…

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Article • Predicting plaques

Exposing the secrets of the heart

Coronary interventions often rely more on art than science as the decision to treat a patient tends to be based on what clinicians can see, a subjective interpretation of cardiac imaging. Two new techniques have emerged for cardiovascular diagnostics that are enabling software to help surgeons and cardiologists measure, and thereby better manage cardiac disease.

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Article • Data management

Cardiac IT made simple

When Michael Ziller, Head of IT at the Bethanien Hospital in Moers, Germany, was looking for a provider of cardiac IT applications that not only offered standard applications for ECGs as well as long-term ECGs and long-term blood pressure measurements, he realised there was not much on the market. ‘We had an additional challenge for this project in that we wanted all data to run via just one…

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Article • Intervention

Hybrid ORs: not equally beneficial for all facilities

The hybrid operating room is one of the most innovative developments in the surgical sector. The combination of interventional and minimally invasive surgical procedures is exciting for many clinical disciplines. The room design, intraoperative imaging techniques as well as interdisciplinary collaboration play a pivotal role in this.

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Article • Transplants

Cell-free DNA offers several advantages

As part of a national, joint research project in cooperation with Chronix Biomedical (San Jose, CA/USA/Göttingen/Germany), Professor Michael Oellerich MD is on new biomarkers in organ transplantation, aiming to develop personalised immunosuppression for patients. This also entails the development of molecular test procedures, among others for the early detection of rejection. The keyword here is…

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The vascular bypass revolution

Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor vessel healing, leading to vessel graft occlusion. To improve the outcome of bypasses, researchers from the University of Geneva (UNIGE) work together with medical doctors from…

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Sponsored • Respiratory support

Extracorporeal technology eases stress

Conventional therapy for ARDS patients and for patients with exacerbation of chronic obstructive pulmonary disease (COPD) has relied on invasive mechanical ventilation. Mechanical ventilation, however, has several major drawbacks: sedation has to be induced and the air being pressed into the lungs with positive pressure can damage the pulmonary alveoli or the diaphragm. Moreover, even maximum…

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News • Iso-acoustic focusing

Ultrasound method increases awareness about cancer cells

In brief, the new method involves exposing cells to ultrasound when they flow through a so-called micro-channel inside a chip. The individual cells are separated in the acoustic field and by studying the cells’ lateral movement at the end of the channel it is possible to identify the acoustic properties of the cells. Conversely, if you know the cells’ acoustic characteristics, you can detect…

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Sponsored • ARIETTA Prologue

Mobility at your fingertips

ARIETTA Prologue has been designed especially for the point-of-care (POC) ultrasound market. Thanks to its intuitive and simple operation, it fulfils the fundamental role of a portable ultrasound system, bringing the clinical benefits of diagnostic ultrasound into new areas of healthcare.

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Sponsored • Breakthrough

How Dual Source technology is revolutionizing CT

Since launching Somatom Definition in 2005, Siemens has continued to develop Dual Source technology in order to overcome the remaining challenges in computed tomography. This significant development has made it possible to produce diagnostic images of a patient’s beating heart and coronary vessels without having to artificially lower their heart rate, for example. Scanning speeds that were…

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News • MOZART

Imaging cells and tissues under the skin

Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal.

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News • MS

How do immune cells enter the cerebrospinal fluid?

A research team headed by scientists at the Institute of Neuroimmunology and the Institute for Multiple Sclerosis Research (IMSF), University Medical Center Göttingen (UMG), has gained new insights into the immune function of cerebrospinal fluid (CSF). They used real-time microscopy to film the lively trafficking of immune cells between the CSF and the nervous tissue. Here the meninges play the…

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News • Peripheral artery disease

Treating poor blood circulation with injectable gel

Bioengineers and physicians at the University of California, San Diego have developed a potential new therapy for critical limb ischemia, a condition that causes extremely poor circulation in the limbs and leads to an estimated 230,000 amputations every year in North America and Europe alone to prevent the spread of infection and tissue death. The new therapy could prevent or limit amputations…

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News • Real-time imaging

Clearer picture of stroke damage

According to the American Heart Association, ischemic strokes account for nearly 90 percent of all strokes. They occur when a blocked artery prevents blood from getting to the brain and usually result in long-term disability or death. Now, a team of researchers led by the University of Missouri School of Medicine has developed a new, real-time method of imaging molecular events after strokes - a…

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News • Drug delivery vehicles

Soap bubbles for treating stenosed blood vessels

Liposomes are currently used as drug delivery vehicles but recognized by the immune system. Scientists from the universities of Basel and Fribourg have shown that special artificial liposomes do not elicit any reaction in human and porcine sera as well as pigs. The study was published in the Journal Nanomedicine: Nanotechnology, Biology, and Medicine.

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Interview • Cardiology

Rethinking acute aortic syndromes

Technological advances in CT imaging have sparked a veritable explosion of imaging data. Pushing against the rush of novel imaging findings there is, what Dr Geoffrey Rubin calls, the slow wave of adoption in medicine, the acceptance and agreement of the clinical community for new diagnostic assessments.

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Article • Cardiology

Big data in cardiac CT

CT angiography (CTA) is evolving from a morphological – anatomical – to a functional imaging modality. In the past two years, cardiac CT perfusion measurement techniques were launched that predict which lesion will cause a reduction in blood flow.

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News • bio-hybrid

A microchip to build a first-ever artificial kidney

Vanderbilt University Medical Center nephrologist and associate professor of medicine Dr. William H. Fissell IV, is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient’s own heart.

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Low blood flow in back of brain increases risk of recurrent stroke

Patients who have had a stroke in the back of the brain are at greater risk of having another within two years if blood flow to the region is diminished, according to results of a multicenter study led by researchers at the University of Illinois at Chicago. These stroke patients are the most likely to benefit from risky intervention to unblock arteries, and they can be identified using a new…

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News • Oncology

Scientists use dead bacteria to kill colorectal cancer

Led by Professor Teoh Swee Hin, scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.

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Article • Diagnostic

SuperSonic reveals micro vessels with AngioPLUS

Building on an innovative ultrasound technology that continues to yield break-through capabilities, SuperSonic Imagine is introducing AngioPLUS, a third diagnostic functionality for its Aixplorer platform that promises to be instrumental in the diagnosis of cancerous tissues as well as musculoskeletal pathologies.

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Article • Revolution

3-D printed muscles

With 3-D printing revolutionising manufacturing, its healthcare potential is being explored for medical devices, prosthetics, dentistry and drug development. One area under the spotlight is the creation of artificial muscles using a 3-D printing system. Dr Fergal Coulter, who has played an important role in helping develop the technique, outlined the manufacturing process, which he invented for…

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Article • Surgery

World’s first bilateral hand transplant on a child performed

Surgeons at The Children’s Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world’s first bilateral hand transplant on a child. Earlier this month, the surgical team successfully transplanted donor hands and forearms onto eight-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney…

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News • Trinias MiX-Package

Shorter treatment times and less contrast media

In the year of its 140th anniversary, Shimadzu has released the new Trinias MiX package (Minimally invasive eXperience) to support less invasive treatments through a variety of applications. The Trinias MiX package is an exten¬sion of the Trinias angiography system, which facilitates high-level interventions through proprietary image processing technology. Shimadzu provides functional…

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News • Hematology

Flowing toward red blood cell breakthroughs

A team of researchers from Brown University, ETH Zurich, the Universita da Svizzera Italiana (USI) and Consiglio Nazionale delle Ricerche (CNR) is using America’s most powerful supercomputer to help understand and fight diseases affecting some of the body’s smallest building blocks.

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News • Hours at a computer

Short walk can reverse vascular dysfunction

Across the country, many employees are seated at desks for the majority of an eight-hour workday. As technology creates an increase in sedentary lifestyles, the impact of sitting on vascular health is a rising concern. Now, researchers from the University of Missouri School of Medicine have found that when a person sits for six straight hours, vascular function is impaired — but by walking for…

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The mechanism that impairs blood flow with aging

With the world’s elderly population expected to double by 2050, understanding how aging affects the body is an important focus for researchers globally. Cardiovascular disease, the No. 1 cause of death worldwide, often is associated with aging arteries that restrict blood flow. Now, University of Missouri researchers have identified an age-related cause of arterial dysfunction, a finding that…

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News • Improved blood flow

Saving Lives using new stent graft design

Vascular surgeon Pat Kelly of Sanford Health in Sioux Falls, South Dakota, knew his patients were doing better with the stent graft he designed, but he wanted a better understanding of the mechanics before testing the device more widely in a clinical trial. For that, he reached out to South Dakota State University. Associate professor Stephen Gent in mechanical engineering had done computational…

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News • Ars Electronica Center

Virtual journey through the heart

Medical research and art sometimes meet at their finest: experts from the Fraunhofer Institute for Medical Image Computing MEVIS in Bremen produced a three-dimensional movie, showing the human heart in full action. The organ beats and pumps, and special techniques visualize the dynamic flow of blood in the vessels. The sequence is part of a new interactive three-dimensional experience to be…

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Radial artery catheter failure

2.5 million radial arterial catheters (RAC) are used annually in Europe (USA: 8 million), commonly to monitor arterial blood pressure and take blood samples in surgical, A&E and ICU units. They can fail. For a study of mechanisms that might lie behind premature RAC failure and complications related to RAC in clinical use*, at team at the Radiology/Ultrasound and Anaesthesiology Department,…

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Sponsored • Best Places to Work

A laboratory fit for a future decade

Fostering a collaborative way of working won the UK’s Dartford and Gravesham NHS Trust recognition as an elite public sector healthcare employer, recently judged one of the top 100 ‘Best Places to Work’. The trust, led by chief executive Susan Acott, has created an energy-driven, patient-focused culture within the hospital, reflected by staff at all levels. This has been the driving force…

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Sponsored • Workflow

Confidence in Hematology, Results with Beckman Coulter

Wallace Coulter, one of the founders of Beckman Coulter, was motivated by a belief that science should serve humanity. This was the inspiration behind the principle he invented that became the basis for all blood counting solutions. This same drive to keep the science of hematology moving forward is behind Beckman Coulter's new ©Automated Intelligent Morphology© (AIM), a multidimensional,…

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Article • Open platform

Hitachi powerfully expands Oasis 1.2T MRI

Hitachi has double-down its bet on the advantages of open-platform MRI by introducing a new generation of the Oasis 1.2T scanner this year at RSNA. The jump to new processing power and the new Origin 4.0 MR Operating Software effectively enhances capabilities with a range of new applications for neuro, orthopedic and vascular imaging as well as enhancing routine exams for women's health and…

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News • Technology

Diabetes: Smart insulin patch could replace painful injections

Painful insulin injections could become a thing of the past for the millions of Americans who suffer from diabetes, thanks to a new invention from researchers at the University of North Carolina and NC State, who have created a “smart insulin patch” that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream whenever needed.

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News • Blindness

OCT technology detects blood vessel in the eye

Research published in the Proceedings of the National Academy of Sciences (PNAS) demonstrates that technology invented by researchers at Oregon Health & Science University’s Casey Eye Institute can improve the clinical management of the leading causes of blindness. Optical coherence tomography (OCT) angiography could largely replace current dye-based angiography in the management of these…

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Sponsored • First hand experience

Improving point-of-care ultrasound training in intensive care medicine

Dr Sven Ballnus is Director of the Department of Intensive Care Medicine at the Hospital Centre Biel/Bienne, Switzerland, and an active member of the European Society of Intensive Care Medicine. Formerly a chief consultant in intensive care medicine at Westküstenkliniken in Heide, Schleswig-Holstein, Germany, he oversaw the development of an ultrasound course focusing on the specific needs of…

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Sponsored • Automation

Scottish NHS group endorses automation

It’s thumbs up for Siemens Healthcare Diagnostics’ Aptio Automation, following a two-year deployment by Dundee-based National Health Service (NHS) Dundee, the first north European healthcare organisation to use the system to consolidate formerly siloed biochemistry, immunology, haematology and haemostasis testing onto a single automation track.

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Article • Head and Neck Radiology

The Radiologist’s Fear of Spaces

Imaging the head and neck is only rarely practised in radiology training and is highly complex and particulate, which is why, during our discussion with Professor Birgit Ertl-Wagner, Head of MRI at the Institute for Clinical Radiology at Grosshadern Hospital, Ludwig Maximilian University, Munich, she pointed out that many radiologists are not comfortable with orientation around this area. When…

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News • Stroke

Effectiveness of treatment confirmed

A research paper published in the New England Journal of Medicine (NEJM) today confirms earlier findings that a procedure called endovascular therapy (ET) for ischemic stroke is the best treatment option for many patients by reducing the incidents of disability. This is the fourth research paper published this year that confirms the efficacy of the treatment.

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Sponsored • Liver Cancer

New Treatment Approved for EU

A new treatment for liver cancer developed by the University Medical Center (UMC) Utrecht has received the European CE mark for quality and safety. This implies that hospitals throughout Europe can now start using this innovative treatment that uses radioactive holmium microspheres to attack liver tumors. The treatment is being marketed by Quirem Medical, a spin-off company of the UMC Utrecht.

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Article • Computer Model

How our livers will store fat?

As part of an effort to understand how an experimental drug for atherosclerosis causes the build-up of fat in the liver, scientists have developed a computer model that can predict how the rate at which liver stores fat in response to various situations.

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Article • Influential innovations

Unfolding new vistas for MRI, PET and PET/CT

The importance of cardiac imaging is increasing, but nuclear medicine procedures are by no means obsolete, observes Okan Ekinci, during our EH interview with the Siemens Vice President for Healthcare Consulting & Clinical Affairs about the latest innovations for cardiology.

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Article • Frostbite

Chilled to the bone!

For people living in Chamonix-Mont Blanc medical services at the nearby community hospital have been reduced to little more than a stopover visit before being referred down the mountain to larger facilities in the network of the Hospitals of Mont Blanc Country. Report: John Brosky

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Article • Intensive Care

The 35th ISICEM

Held every year in March, for the past 35 years, the International Symposium on Intensive Care and Emergency Medicine has been organised by the Departments of Intensive Care and Emergency Medicine at Erasme University Hospital, Université Libre de Bruxelles, in association with the Belgian Society of Intensive Care and Emergency Medicine (SIZ). For three and a half decades, the event’s main…

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Sponsored • Point-of-Care

M9 brings maximum mobility

For medical ultrasound it’s quick, easy and portable – and so popular with Professor Christoph Dietrich, chief of Medical Department 2 at Caritas Hospital, Bad Mergentheim, one of the first physicians worldwide to test the M9 in clinical routine. ‘The compact Mindray colour Doppler system is about the same size as a notebook computer. The imaging suite comes to the patient,’ the…

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Sponsored • Fast Ultrasound

Ultrasound system sharpens paediatric hepatic imaging

Ask about UltraFast ultrasound and you might expect a technical answer explaining why the ultrasound is faster. However, for Stéphanie Franchi-Abella MD, fast means just fast, an ultra-quick acquisition she can take of a squirming, agitated new-born in the blink of an eye. ‘These babies are small and breathing rapidly, the organs are moving fast in the image and it’s sometimes difficult to…

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Article • Liver

Stellate cells control regeneration and fibrosis

Scientists from the German Cancer Research Center (DKFZ) and the Medical Faculty in Mannheim at Heidelberg University are searching for new approaches to prevent liver fibrosis. They have identified a surface molecule on special liver cells called stellate cells as a potential target for interfering with this process. When the researchers turned off the receptor, this led to reduced liver…

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Mechanical thrombectomy improves outcomes in acute ischemic stroke

Stroke resulting from rupture or interruption of blood flow in brain vessels can lead to devastating consequences for patients, their families and society. Steady progress has been achieved in the last 20 years in stroke treatment through better prevention, establishment of stroke care units and the use of clot-busting drugs (intravenous thrombolysis).

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Seeking congenital cardiac defects

Congenital heart defects are the most common congenital disorders found in newborns – around one in a hundred babies are affected. This type of heart defect can be reliably diagnosed with ultrasound, usually during the detailed foetal scan carried out halfway through the pregnancy. Report: Brigitte Dinkloh

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Simply Superb Microvascular Imaging

‘An intelligent imaging tool, Superb Microvascular Imaging (SMI) moves beyond conventional colour Doppler technology by applying a unique algorithm allowing visualisation of small vessels with low velocity, while maintaining high resolution, minimal motion artefacts and high frame rates,’ Toshiba proudly reports.

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A new tool for biochemical analyses

Although telemedicine could improve the quality of life of patients with chronic liver diseases, viable home care systems are still lacking. However, within the EU-project ‘d-LIVER’ (www.d-liver.eu) scientists at the Fraunhofer Institute for Biomedical Engineering IBMT, in St. Ingbert, Germany, are working with European partners to develop an IT- and cell-based system that will help chronic…

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Biologised medical technology

New approaches, solutions and outlooks on biologised medical technology developed in the Berlin metropolitan region were presented at this year’s annual 'Medical technology meeting place' in Berlin, which presents the latest research, new product developments and best practice examples from the greater-Berlin area. report: Bettina Döbereiner

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Article • Research

3D printers help neuroradiologists

The treatment of cerebral aneurysms is often very complex and initially it is not always obvious which type of treatment is best suited for an individual case. In October, during the Annual Congress of the German Society for Neuroradiology e.V., a working group from Hamburg introduced a procedure that enables the production of exact copies of individual aneurysms with a 3D printer.

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Refinements and advancements galore

The Aplio, Toshiba’s flagship ultrasound scanner, has been extensively advanced and essentially turned into a new system. The highly innovative Japanese company in imaging diagnostics has refined the successful Aplio series of scanners and introduced it internally in Frankfurt at the beginning of October.

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To pulse or not to pulse

Whether mechanical, temporary cardiac assist systems should pulsate in the same way as a biological heart is a discussion topic, which raises the pulse rates amongst all those involved within the industry and in hospitals.

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Laboratory automation

On the leading edge of automation for medical laboratory testing, Siemens Healthcare rolled out an impressive suite of new products at IFCC WorldLab 2014 in Istanbul, Turkey that are ‘exactly aligned, and even anticipate, customer needs in central lab operations,’ according to Franz Walt, CEO for the Chemistry, Immunoassay, Automation and Diagnostics IT business unit within Siemens’…

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Curse or blessing?

A small prick to sample blood instead of complex pathological or other diagnostic procedures – this is how early cancer diagnosis will be in the near future. Blood tests to diagnose tumorous diseases early are already being researched for clinical use.

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The ESPOIR Study

Professor Axel Haverich and team at the Clinic for Cardiothoracic, Transplant and Vascular Surgery in Hanover Medical School (MHH) have been carrying out research into decellularised heart valves for over 15 years. They trialled a procedure – initially in the laboratory and in animal experiments – which does not cause tissue rejection, is hoped to last a lifetime and, in the case of children,…

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The complex science behind microbubbles

At Bracco Suisse SA in Geneva all efforts are dedicated to contrast media for ultrasound scans. During their visit to the firm’s research centre and manufacturing site, Daniela Zimmermann and Ralf Mateblowski met with François Tranquart MD PhD, general manager of the Bracco Suisse research centre, to hear why SonoVue is now Europe’s most popular ultrasound contrast agent, with research…

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Intra-aortic balloon pump pros & cons

Since cardiac surgeon Adrian Kantrowitz, of the Maimonides Medical Centre, Brooklyn, first introduced intra-aortic balloon pulsation (IABP) into clinical practice in 1967 (Surg Clin North Am. 1969 Jun; 49 (3) :505 -11), the technique has been considered the method of choice for short-term mechanical cardiac support following a heart attack.

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Endoscopic Hemostat stems bleeding

A few years ago the American forces succeeded in dramatically lowering the mortality of soldiers from gunshot wounds with the help of a new, haemostatic powder. These silicate crystals, which attach to a wound, not only stem external bleeding but also internal bleeding resulting from stomach or duodenal ulcers, tumours or rare types of vascular deformities.

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Art meets science

The future will be aesthetic or, put another way, Art meets Science. With this motto, the 43rd Congress of the German Society for Endoscopy and Imaging Procedures e.V., jointly held in Munich with six other specialist associations, demonstrated that aesthetic means the brilliance of images generated by the latest generation of X-ray, CT, MRI and ultrasound equipment.

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PET/MR: The opportunities are almost unlimited

MRI has become the gold standard for many indications in cardiac imaging, apart from imaging the coronary arteries. For function and morphology assessment, MRI is the leading technology. A further advance into as yet unknown territory is myocardial imaging aided by one of the first integrated 3-Tesla PET/MR systems currently used at the Institute of Radiology, Essen University Hospital,…

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Article • Infections

Maintain perioperative normothermia

Even mild perioperative hypothermia can have significant effects on rates of surgical site infections (SSIs), morbid myocardial outcomes, blood loss and transfusion requirements, altering the response to drugs, extending recovery rates, hospital stay and patient discomfort.

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Breathing space

If the hopes of inventors are to be believed, in around 20 years’ time there will be ‘real artificial lungs -- for now the endpoint of a history that began 84 years ago with the invention of the iron lung. Until then, non-invasive and invasive mechanical respiration will continue to dominate the hospital, complemented by extracorporeal procedures for blood oxygenation and decarbonisation,…

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IROS 2012

Controversies were certainly aired when 800 radiologists gathered in Salzburg for The Interventional Radiological Olbert Symposium - a meeting of the German, Austrian and Swiss Societies for Interventional Radiology (DEGIR ÖGIR and SGCVIR) – and certainly some striking new interventions were presented. Michael Krassnitzer reports

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ECR 2013: Cardiac imaging is picking up speed

They examine the structure of the heart muscle with magnetic resonance imaging (MRI) or evaluate the status of the coronary vessels with computed tomography (CT): radiologists increasingly use imaging methods to prevent or to assess cardiac diseases.

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The end of blooming effects

During the RSNA 2011, Professor Uwe J Schoepf MD, was asked what will be the chosen procedure of the future in cardiac imaging, he answered without hesitation: ‘Definitely CT,’ and, the Director of Cardiovascular Imaging at the Medical University Charleston, South Carolina.

A niche with no lobby

Italy is a front runner in diabetic foot revascularisation. Among the country’s pioneers is Professor Roberto Gandini, at the Diagnostic Imaging and Interventional Radiology Department, University of Tor Vergata in Rome, who has developed and improved new technical options in peripheral vascular disease intervention, a technique that now saves about 92% of patients from major amputations due…

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Coronary Heart Disease can be diagnosed and treated earlier using new techniques

Prof. Uwe Nixdorff from the European Prevention Centre, Düsseldorf advocates cardiologists combine IMT measurement with ALOKA’s pulse wave intensity function to check for unseen coronary heart disease: “This technique is currently seldom used, however in my experience it provides a more complete picture and enables me to treat patients earlier for life-threatening conditions that are often…

COMPAMED 2011 - Trend Report

Modern medical technology is evidently held in high esteem by the general population. In a recent survey conducted by the market research institute Emnid commissioned by the industry association SPECTARIS, about 80% of the patients surveyed said that under certain circumstances they would be willing to pay more for their health insurance in return for consistent treatment with state-of-the-art…

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Papworth Hospital: A constant continuing success

Recent events have again underlined the reason why Papworth Hospital in ambridgeshire, England, maintains a enowned international reputation for cardiac and thoracic procedures. As Britains largest specialist cardiothoracic hospitals, over 2,000 major heart operations were performed there in 2010. In the year ending 1 April 2011, 824 patients had coronary bypass operations, including urgent,…

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Innovations in non-invasive diagnostics

Although the 17 lectures delivered at this year‘s Medical Technology Congress in Berlin, Germany, focused on topics ranging from experimental and clinical research to routine daily diagnostic methods, the pervading interest was in the improvement, development and distribution of non-invasive imaging devices and corresponding software.

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When the heart gives up

This April the 77th Annual Meeting of the German Cardiac Society (DGK) presented over 300 events with 1,800 speakers, covering the entire spectrum of cardiovascular diseases, from fundamental research to clinical routine. Professor Gerd Hasenfuss, Director of the Department of Cardiology and Pulmonology and Chair of the Heart Research Centre in Gottingen, particularly requested a focus on …

Contrast enhanced tumour studies

Medical imaging has recently advanced so rapidly that it should halt. Applying more power to computed tomography (CT) and magnetic resonance imaging (MRI) scanners is becoming too dangerous for patients and healthcare workers. Magnets for the next-generation MRIs are so powerful that they must be moved to a separate building on hospital campuses, while CT radiation levels have risen to alarming…

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Old technology in new outfit

Looking at the 5th dimension of a CT image is old hat. Back in the 1980s there were many installations with rapid kV switching, a dual energy procedure, which were mainly used for bone density measurements. Basically, the 5th dimension is the ability to determine the atomic number as well as density of materials, which facilitates tissue differentiation even when there is the same attenuation.

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Easy breathe - new tools for prolonged lung support

Often a life-saving intervention, mechanical ventilation also has some serious drawbacks: the need for sedation, the risk of ventilator associated pneumonia, intubation or tracheostomy related complications. In 1972, Donald Hill from Pacific Medical Centre, Los Angeles, reported the first successful long-term mechanical lung assist device with extracorporeal membrane oxygenation (ECMO).

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The 3rd Annual General Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry

Different tests bring different results, and results of the same types of test vary from laboratory to laboratory. "In the case of test procedures for autoimmune diseases there are incredible discrepancies," confirmed Professor Manfred Herold, head of the Laboratory for Rheumatism at the University Clinic for Internal Medicine One, Innsbruck. The reason: "There are no standards for…

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Pocket-size echocardiography

When a patient needs transthoracic or transoesophageal echocardiograms there are two options – transportation to an ultrasound machine in the echo lab, or wheeling a machine to the bedside. Now there is a third option. The new Vscan from GE Healthcare is a hand-held ultrasound device that is pocket-size; cardiologists can carry with them at all times, enabling ultrasound to be a part of any…

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Microchip separates and extracts tumour cells in the blood

Ikerlan-IK4 and Mondragón Unibertsitatea are taking part in a project initiated by the Spanish National Research Council, CSIC, and which has developed a microchip capable of separating and extracting tumour cells in the blood stream by means of ultrasonic waves. The Foundation General Hospital of the University of Elche, together with researcher Alfredo Carrato, has also collaborated on this…

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Heart in hand

Surgeon Alain Carpentier is ready to remove a patient’s heart and replace it with a mechanical device he spent 15 years developing. By 2013 the procedure will be performed on 50 European patients as part of a clinical trial to win CE approval for the world’s first fully implantable artificial heart.

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Arteries seen in a new light

New imaging technologies are opening a new chapter in interventional cardiology by offering something this widely practiced procedure has been missing -- vivid clinical evidence to assess effectiveness. Interventional cardiology has moved rapidly from opening blocked arteries by crushing plaque with inflatable balloons to reinforcing the walls of the re-opened arteries with flexible metal stents…

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Stiff heart - The ‘stepchild’ of cardiology

Patients with heart failure with normal ejection fraction (HFNEF) also referred to as ‘stiff heart’, show a normal ejection fraction and severe diastolic dysfunction. President of the Austrian Society of Cardiology, Professor Irene Lang warns: ‘It is particularly concerning that stiff heart is a little known and insufficiently researched cardiac condition -- a stepchild in research,…

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Getting to the heart of things

Not only is heart failure one of the single biggest causes of morbidity and mortality in man, but the incidence of the condition is steadily increasing. Rising to this challenge, innovative medical diagnostic techniques with ever greater performance are constantly being introduced so that early, unambiguous detection of the underlying condition is now possible, enabling the prompt initiation of…

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Coming soon: MEDICA 2010

Looking ahead to MEDICA 2010 (17 to 20 November) the signs are good. The high number of registrations is a sign of optimism in the medical technology industry and the number of exhibitors has already seen a significant increase in comparison to last year. With six months left to go until the fair begins, some 115,000 square metres of exhibition space had already been booked.

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Negative pressure wound healing technology

Despite some uncertainty about how it works, there is a growing consensus that Negative Pressure Wound Therapy (NPWT) – also known as Vacuum Assisted Closure (VAC) – is revolutionising wound care. Speaking at the 1st International Surgical Wound Forum, held recently in Amsterdam, surgeons from Europe and the USA predicted the growing use of this innovative technology across the spectrum of…

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Health informatics in practice

The Health Informatics Congress held in the UK this April, revealed how IT is helping health Trusts across the UK to take innovative steps in the way they respond to patients’ needs. The Clinical Showcase session examined how Trusts are coping with new patient administration and reporting systems and, in particular, how Cerner Millennium and Lorenzo systems are being implemented.

New twelve-month data for Nevo stent

At 12 months the NEVO Sirolimus-eluting Coronary Stent has continued to demonstrate excellent safety and efficacy outcomes compared to Taxus Liberte according to new data presented today from the NEVO RES-I clinical trial. These results were presented as a late breaking trial at EuroPCR, the leading medical conference in Europe for physicians specializing in interventional cardiovascular…

What´s hot in cardiology?

Hot topics to be covered during the EuroPCR Forum sessions are the challenging implementation of the best standard of care for STEMI patients throughout Europe (with the timely use of stents), the introduction of transcatheter aortic valve implantation (TAVI) in clinical practice and the challenges related to bifurcation treatment options.

Secret to Healing chronic wounds might lie in tiny pieces of silent RNA

Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA. The Ohio State University researchers discovered in a new animal study that this RNA segment in wounds with limited blood flow lowers the production of a protein that is needed to encourage skin cells to grow and close over the sore.

Imaging technique useful for planning cardiac procedures

For a patient with heart failure, checking whether the heart could benefit from bypass surgery or a stent is critical to ensuring survival. One imaging technique, positron emission tomography (PET) with the imaging agent fluorodeoxyglucose (FDG), may provide doctors with the information they need to make more informed treatment decisions, according to research published in the April issue of The…

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The new world of biomarkers

While biomarkers are acknowledged as useful tools in the early assessment of patient response to treatment, radiologists are less clear on how they can be applied in clinical practice. The ECR session Biomarkers: new word, new world, new work? explored a number of new applications for biomarkers with senior radiologists discussing their relevance in different areas.

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New Ultrasound system in HI VISION Family

Right on time for the 100th anniversary of its foundation, Hitachi Medical Systems Europe Holding AG is presenting the latest member of the new HI VISION generation at this year's ECR in Vienna: the HI VISION Avius. The HI VISION Avius is a user-friendly, digital and fully software orientated ultrasound system for modern diagnostic applications. Highlighted are its pioneering patient-friendly…

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GE’s Vscan takes ultrasound anywhere

Although small, Vscan is a prescription device for ultrasound imaging, measurement and analysis in the clinical applications of abdominal, cardiac (adult and paediatric), urological, foetal/OB, paediatric and thoracic/pleural motion and fluid detection, as well as for patient exams in primary care and special care areas.

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The diagnostic laptop

Toshiba America Medical Systems, Inc.’ reports that its new Viamo laptop device is ‘…the industry’s no-compromise ultrasound system with advanced radiology capabilities, previously unavailable on hand-carried systems’, adding that It offers the same premier image quality as larger, more expensive ultrasound systems, but at a lower price.

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Ultrasound device in pocket size

GE Healthcare presented Vscan, a new, pocket-sized visualization tool developed to provide physicians with imaging capabilities at the point-of-care. Roughly the size of a smart phone, Vscan houses powerful, ultra-smart ultrasound technology that provides clinicians with an immediate, non-invasive method to help secure visual information about what is happening inside the body. Vscan is portable…

Laptop ultrasound system receives FDA clearance

Designed to meet the needs of today’s hospitals by combining portability with high-end radiology features, Toshiba America Medical Systems, Inc.’s new Viamo laptop ultrasound system has received FDA clearance. The Viamo is the industry’s no-compromise ultrasound system with advanced radiology capabilities, previously unavailable on hand-carried systems. Toshiba’s Viamo provides the best…

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Ideaworks

Many years ago, five self-made millionaires were interviewed about their work. The last question posed was: ‘Is there one thing to which you could attribute your enormous success?’ Without hesitation, four answered: ‘Energy!’ The fifth quipped, ‘Luck’. By the law of averages energy is thus a vital ingredient. However, there are many other essential assets and luck is the least of them.

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Handwriting revisited

A specialised brain area involved in the production of written language was first empirically described by 19th century scientist S. Exner. At that time, the only way to investigate was by post mortem study of patients who had experienced writing problems during their lives. Now, in France, a team of researchers led by Jean François Démonet, has applied state-of-the art technology to study…

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Hepatocellular carcinoma

Cases of hepatocellular carcinoma (HCC), one of the most frequently occurring cancers throughout the world, are expected to increase dramatically in the next 10-15 years in Germany alone. The main reason is the increased occurrence of fatty hepatitis. Thus, in the future, interventional radiologists will also be increasingly involved in HCC patients treatment.

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40 years of MEDICA

When we organised the first Diagnostic Week in Karlsruhe, in 1969, no one could have known that this event would one day turn into the annual highlight in the world of medicine, reflected Dr Wolfgang Albath, laboratory medicine pioneer and one of the founding fathers of MEDICA the world`s largest medical trade show. Initially planned as a moving exhibition, the show has been based in…

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The role of exercise training in cardiovascular health

Western societies are struggling to pay for their ever increasing medical budgets. In the US up to 393 billion US-$ were spent in 2005 for cardiovascular diseases alone. Based on epidemiologic studies in primary prevention it is reasonable to estimate that 30% of coronary heart disease and stroke could be prevented by 2.5 hours of brisk walking per week.

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Met at KIMES

During KIMES, Karoline Laarmann (European Hospital) met with Joong-Ho Lee, Senior Executive Vice President of the ultrasound systems manufacturer MEDISON, the Korean firm that entered the ultrasound market in the 1980s and quickly established a global reputation for innovative developments (e.g. the firm produced the first commercial real-time 3-D ultrasound scanner).

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Non surgical mitral valve repair: First enrollment in ACCESS-Europe study

Evalve, Inc., the leader in the development of devices for the percutaneous repair of cardiac valves, announced the first enrollment in the ACCESS-Europe study, a post-market observational study of the MitraClip therapy in Europe. The system is the first commercially available treatment option for non-surgical mitral valve repair for patients suffering from the effects of functional and…

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EAU hot topic: Imaging in urological oncology today

Big discussions are expected at the upcoming European Association of Urology (EAU) Congress in Stockholm* when urologist Dr Jochen Walz (right), of the Urological Department at the Institute Paoli-Calmettes, Marseilles, France, presents the forum: Imaging in Europe: Who, where, what, how many! and M F Coelho, of the European Society of Urological Imaging (ESUI) describes the Clinical utility of…

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Cardiovascular MRI

The role of magnetic resonance imaging (MRI) to assess the effect of therapy in patients with acute myocardial infarction was demonstrated in a series of papers during the 12th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance (SCMR), held in Orlando, Fla. USA (29 Jan - 1 Feb).

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New tumour ablation technique in clinical practice

Electroporation is going to widen the spectrum of cancer treatment in the future. While other tumour ablation techniques like cyroablation, radiofrequency ablation and microwave ablation work with intense heat or cold to kill cancer cells, irreversible electroporation (IRE) uses electric pulses allowing minimal collatoral damage to surrounding tissue. First clinical applications have already…

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Non-invasive applications in clinics

If a patient is delivered to the clinic with pulmonary complications, the clinic has to decide which type of therapy is suitable. In addition to purely medical aspects other criteria also play an important role such as: the mental and physical stress on the patient due to the treatment, the time it takes to implement a measure and the overall economics of the procedure.

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Plasma vaporisation

Benign prostatic hyperplasia (BPH) is the most common cause of voiding disorders in men. The hyperplastic tissue constricts the urethra and leads to lower urinary tract symptoms (LUTS) that can be differentiated into irritative and obstructive symptoms. These can quite dramatically impact on the quality of life of affected people.

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Cardiohelp

Maquet has launched Cardiohelp, the world's smallest, lightest heart-lung machine, that can not only provide a total therapy solution for heart surgery, cardiology, intensive and emergency care, but also, due to its suitcase size and 10 kg weigh, the device can be carried by just one person onto a helicopter or ambulance for mobile use.

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Article • Radiation management

'Dose hysteria' and the 320-slice CT scanner

Sometimes radiation dose is a topic discussed hysterically. Dose discussion is necessary, but should be carried out based on the highest levels of knowledge and seriousness. For the last few months, Dr Patrik Rogalla, Senior Consultant at the Charité, Berlin, specialist in diagnostic radiology and Head of the Computed Tomography Department at Campus Mitte, University Medicine Berlin, has been…

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Cardiohelp

Maquet has launched Cardiohelp, the world's smallest, lightest heart-lung machine, that can not only provide a total therapy solution for heart surgery, cardiology, intensive and emergency care, but also, due to its suitcase size and 10 kg weigh, the device can be carried by just one person onto a helicopter or ambulance for mo-bile use.

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CT: Optimising dosage

AquilionONE is the first CT scanner capable of imaging whole organ regions up to a width of 16 cm in one rotation and within a split second. Based on the raw volume data, rapid dynamic processes within an entire organ (e. g. heart, pancreas, kidney or brain) may be diagnosed with a time interval of 50 ms, i.e. with a rate of 20 volumes per second.

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EVINCI

The European multi-centre, multi-modality cardiac imaging project that could lead to a more intelligent and less costly use of today's technology in cardiac care.

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Further increase in number of exhibitors

The COMPAMED, the leading specialist international trade fair for suppliers to the medical manufacturing market, is held parallel to the MEDICA, the world's largest medical trade fair, each year and showcases the dynamism and innovative power of the medical technology sector. The COMPAMED 2008, High tech solutions for medical technology, will, with around 500 exhibitors from 30 nations, once…

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Diabetes: an increasing threat to people and society

Approximately 31 million people in the European Union are suffering from diabetes, a devastating disease with severe consequences for patients and their families, but also for the society at large and the economic prosperity of Europe. This week EH Online will focus on innovative strategies in diabetes care and on new management systems to support physicians and patients alike. Moreover, we will…

Foetal surgery

Almost 25 years ago Michael Harrison of the University of California, San Francisco (UCSF) operated on the bladder of an unborn child. Almost eight years later, surgery was carried out on the diaphragm of an unborn child. His approach was controversial: a paediatric surgeon opened the abdomen and uterus of the pregnant woman, lifted out the foetus, performed the surgery and returned the foetus to…

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ProSound a7

`High performance systems need not be large,´ says Aloka, manufacturer of the new compact ProSound a7, which produces high-resolution images yet can be used in areas with little spare space. `Broadband Harmonics provides high sensitivity and penetration that is comparable to fundamental-frequency imaging resulting in a significant improvement above standard harmonic imaging,´ Aloka reports.

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Article • Varicose veins

Promising way of treating male infertility

Varicose veins in testicles are common and harmless in most of the cases. But they can be the reason for unwanted childlessness. Venous embolization, a minimally invasive treatment, offers the opportunity to improve male fertility, as a study from the University of Bonn, Germany, shows.

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Green tea is an affair of heart

Not only for green tea fanciers. A recent study published in the European Journal of Cardiovascular Prevention and Rehabilitation shows that drinking green tea improves the function of cells lining the vascular system and therefore protect vessels from atherosclerosis, reported the European Society of Cardiology.

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The brain in three dimensions

Stroke treatment is a question of time. The faster the cerebral infarct can be diagnosed, the less the brain will be damaged. But unfortunately it is not always easy to get the patient to a brain scanner within the required three-hour window. Real-time 3D ultrasound might bring the solution, according to researchers from the Duke University in Durham, NC.

CZECH SURGERY NEWS

Rotational artherectomy - Around 33,000 patients are hospitalised annually due to myocardial infarction, but only five percent actually die, thanks to the various state-of-the-art treatments mastered by Czech physicians.

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At a glance

Where are the most high-tech start-ups? That`s an easy one: Silicon Valley. But who comes in a close second? Surprisingly: Israel. Further: Israel ranks Number 1 in terms of availability of scientists and engineers and Number 2 in quality of higher education. The result of this impressive track record is a wide range of successful enterprises and products, particularly related to the life…

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The ProSound a7

With over 200,000 ultrasound systems delivered worldwide, ALOKA, which has been a leading innovator in ultrasound for half a century, continues to enhance the ProSound family of high performance products. At MEDICA this year, the company is introducing its latest development: the ProSound a7. To deliver high definition images on a LCD monitor, ease of use and a compact form design, the ProSound…

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Magnetic Field Imaging improves cardiac diagnostics

Magnetic Field Imaging (MFI) provides cardiologists with an additional tool to detect arrythmia and irregular cardiac blood flow and thus contributes to a more precise diagnosis. While an ECG acquires electric signals produced by the activity of the cardiac muscle, MFI measures the electrophysical function of the heart by determining the magnetic field during a heartbeat.

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First implantable ventricular assist device for long-term use in development

Every fourth patient suffering from an irreversible heart defect and due for a heart transplant dies while waiting for a donor organ despite the use of extracorporeal blood pumps. A new ventricular assist device (VAD), currently under development at the German Aerospace Center (DLR), promises a new approach to help these patients. The fully implantable heart support device might be an effective…

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Magnetic Field Imaging improves cardiac diagnostics

Magnetic Field Imaging (MFI) provides cardiologists with an additional tool to detect arrythmia and irregular cardiac blood flow and thus contributes to a more precise diagnosis. While an ECG acquires electric signals produced by the activity of the cardiac muscle, MFI measures the electrophysical function of the heart by determining the magnetic field during a heartbeat.

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Hot Spots:

A next-generation diagnostic tool for cardiovascular disease, using a nanoscale iron particle, is now under development at a unique industry-government-university named Nano AG. A report from Siemens describes the research and progress at the centre

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Carotid Plaque Imaging

Ischaemic stroke accounts for 80-85% of all cerebrovascular accidents and causes considerable morbidity and mortality, thereby placing a significant burden on western societies. In the UK alone, stroke costs amount to 10.4 billion EUR annually. These events commonly are a consequence of systemic atherosclerotic disease and with the internal carotid arteries supplying 75% of cerebral blood flow,…

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3D Vascular Imaging

Imaging of blood flow with colour Doppler sonography is an established method in prenatal medicine. Today, there are several techniques which offer colour visualisation whose quality is on a par with that of the B-mode. One example of such a technique is Advanced Dynamic Flow (ADF). Looking at two cases, we will describe the clinical use of ADF to visualise fetal vascular tumours. The quality of…

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Discovering Toshiba

Toshiba Medical Systems Corporation is a global medical solutions company covering research and development, manufacture, sales and service for medical diagnostic X-ray systems, CT scanners, magnetic resonance imaging (MRI), ultrasound, nuclear medicine systems, as well as healthcare IT systems and radiation therapy equipment. Daniela Zimmermann, of European Hospital, recently visited Toshiba's…

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Intensivists

Not so long ago, in addition to carrying their normal workload the surgeon, anaesthetist, lung specialist and internist worked in the intensive care unit (ICU). Now, however, the 'intensivist' has arrived - 'A real specialist'

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