A new series of protocols for treating patients with the most severe types of hearts attacks can reduce deaths by more than 50%, and eliminate gender disparities in care and outcomes, according to a new study by Cleveland Clinic.
Hospitalized Covid-19 patients are substantially more likely to harbor autoantibodies — antibodies directed at their own tissues or at substances their immune cells secrete into the blood — than people without Covid-19, according to a new study.
Pancreatic cancer is a disease of the elderly: the average age of patients is 72. In Austria, about 1,600 people are diagnosed each year. Since pancreatic cancer has no specific symptoms, it is not usually diagnosed until the tumor is locally advanced or has already metastasized. Once the tumor has metastasized, it is usually no longer treatable by surgery or radiotherapy. In addition, the drug…
The first large-scale, long-term trial of a new strategy using combinations of very low-doses in one capsule, has demonstrated significantly improved control of high blood pressure - the leading cause of heart attack and stroke. This first large-scale, randomised controlled clinical trial of starting this novel combination blood pressure medication brought blood pressure under control in 80…
A major UK clinical trial led by Queen’s University Belfast has shown how a new approach to reduce the use of mechanical ventilation can greatly improve outcomes for critically ill infants and children. The study, funded by the National Institute for Health Research (NIHR) Health Technology Programme, found that a greater involvement of nurses, minimising sedation use and increasing daily…
A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. The research is presented at ESC Congress 2021. Opioid use disorder, which includes dependence and addiction, affects more than two million people in the US, while opioid overdose is the leading cause of death for those aged 25 to…
The goal of tumour conferences is to determine the best treatment for patients with complex cancers. In these interdisciplinary meetings, doctors from various branches of medicine including oncology, radiology, surgery and pathology convene to talk about a patient's case – however, the patient is rarely present. So far, only a few breast cancer and gynaecological centres in Germany offer their…
Women remain underrepresented in cardiovascular clinical trials despite guidelines and legal requirements developed almost 30 years ago to ensure broader inclusivity. This is according to a report from the American College of Cardiology Cardiovascular Disease in Women Committee published in the Journal of the American College of Cardiology. This lack of representation can limit availability of…
A novel study published in AACC’s The Journal of Applied Laboratory Medicine shows that delaying the second Covid-19 vaccine dose for more than the recommended 3-4 weeks results in higher antibody levels. This finding could play a vital role in shaping vaccine distribution strategies that increase access to the vaccine around the globe.
Roche announced the decision to discontinue dosing in the Phase III GENERATION HD1 study of tominersen (previously IONIS-HTTRx and RG6042) in manifest Huntington’s disease (HD). The decision was based on the results of a pre-planned review of the data from the Phase III study conducted by an unblinded Independent Data Monitoring Committee (iDMC). The iDMC made its recommendation based on the…
A new blockchain-based data analysis app aims to drive collaboration and insights across clinical trials. The tool, developed by software company Clintex, is designed to boost trial efficiency, help drive down the cost of new medicines and expediting their delivery to patients.
GreenBone Ortho, a company specialising in bone regeneration, announces that it has achieved its aim of recruiting 15 patients into the GreenBRIC study. GreenBRIC study is a prospective, open label, single-arm, First-in-Human clinical investigation, in male and female patients, aged between 18 and 70 years, undergoing surgery to correct bone defects using GreenBone Implant, specifically for iliac…
Cancer informatics and digital pathology provider Inspirata announced that King’s Health Partners ECMC and Guy’s and St Thomas’ NHS Foundation Trust will pilot its Trial Navigator software as part of an evaluation the organisations are conducting into how artificial intelligence based automation can improve the identification and efficiency of matching patients with cancer to early phase…
Patients who experience long Covid have reported more than 200 symptoms across 10 organ systems, in the largest international study of ‘long-haulers’ to date, led by scientists at University College London together with a patient-led research collaborative.
Although the coronavirus affects men and women differently, the vast majority of clinical trials do not mention sex/gender, a new analysis of 4,420 studies concludes. Ultimately, it can influence the treatment negatively. The meta analysis is published in Nature Communications. According to the new research, only 4 percent of 4,420 registered studies explicitly plan to address sex and gender in…
A European comparative study has evaluated national organ donation policies in seven countries from an ethical perspective. For the first time, knowledge and attitudes towards organ donation regulations in different European countries were investigated in combination. The study was published in the journal PLOSone.
Rapid tests effectively broke Covid-19 infection chains in spring 2021. This is shown by a model developed by researchers of the ECONtribute: Markets & Public Policy Cluster of Excellence of the Universities of Bonn and Cologne, the Collaborative Research Center Transregio 224 EPoS of the Universities of Bonn and Mannheim, and the Institute for the Study of Labor (IZA). According to the…
In noisy environments, it is difficult for hearing aid or hearing implant users to understand their conversational partner because current audio processors still have difficulty focusing on specific sound sources. In a feasibility study, researchers from the Hearing Research Laboratory at the University of Bern and the Inselspital are now suggesting that artificial intelligence (AI) could solve…
Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…
