Studies

News • Beyond a uniform definition

Diagnosing obesity: new clinical definition outperforms BMI

BMI does not accurately reflect body-fat amount or distribution, which strongly influence health risks. Researchers propose a new definition to better distinguish clinical from pre-clinical obesity.

News • Doctor-patient communication

AI tools to simplify medical reports for patients

Almost half of European citizens face difficulties understanding medical documents. Researchers have evaluated AI language models to simplify medical reports and adapt them into clearer language.

News • Reduced detection

Pulse oximetry may miss sleep apnea in Black patients

Pulse oximeters to determine the severity of sleep apnea may undercount breathing events in Black patients, potentially leading to inaccurate severity classifications, a new study finds.

News • Glioblastoma cell fates

Decoding the rules of brain cancer progression

New research shows that the progression in glioblastoma – the deadliest and most common type of malignant brain tumour – follows predictable patterns, providing hope for future therapies.

News • Transcriptomic atlas

Breast cancer map: charting the course for precision oncology

A molecular map of breast cancer identifies novel forms and provides a foundation for personalized treatments guided by a tumor’s molecular characteristics rather than standard pathology alone.

News • Ejection fraction analysis

AI predicts patient survival from cardiac MRI scans better than clinicians

AI measurements of heart function from MRI scans are more strongly linked to how long patients live after their scan than measurements made by clinicians, according to new research.

News • Circadian genotyping

Prostate cancer radiotherapy: timing matters

Researchers have discovered that the time of day prostate cancer patients receive radiotherapy can influence their risk of developing long-term side effects for treatment.

News • LITMUS studies

MASLD and MASH: Breakthrough in non-invasive liver testing

As first treatments for liver disease MASH enter clinical practice, demand for accurate diagnostics and monitoring options grows. Two new studies outline new ways for non-invasive liver testing.

News • Environmental microbiome study

How hospital wastewater builds antibiotic resistance

Antibiotics excreted by patients promote antibiotic-resistant bacteria in hospital sewers, according to a new study. The insights may contribute to pinpointing the responsible antibiotics.

News • 3D micro-CT reveals malignancy

Breast cancer: hidden diagnostic information in surrounding tissue

Breast imaging focused on calcifications may overlook valuable diagnostic information, a new study finds. The researchers suggest using 3D micro-CT to assess the surrounding tissue microenvironment.

News • Eye tracking as cognitive marker

Unlocking personalised relief for chronic pain with VR

Combining artificial intelligence (AI) with eye tracking in virtual reality could one day help personalise treatment for millions living with chronic pain, according to new research.

News • What's in the bag

Antibiotics in travel luggage: a gateway to building resistance?

Antibiotics may enter a country via airports, when travellers bring them for their own use. Can this contribute to the development of resistant bacteria? A new study assesses the extent of the issue.

News • Machine learning

AI model to detect breast cancer metastasis in lymph nodes

Researchers have developed a new AI model to detect whether breast cancer metastasizes in areas near the chest, specifically the armpit lymph nodes, essential immune system filters.

News • Research on blood proteins

Finding biomarkers for aggressive prostate cancer

Is a prostate cancer slow-growing and harmless, or aggressive and life-threatening? New research shows how blood proteins could reveal clues to prostate cancer risk more than a decade before diagnosis.

News • Acute myeloid leukaemia

Six-gene scoring system could help predict AML survival

Acute myeloid leukaemia (AML) has widely variable outcomes from one patient to the next. Now, researchers have created a new scoring system based on the activity of six different genes to help determine patient survival.

News • Biobank-based study

Large dataset reveals hidden causes of side effects of medicines and vaccines

Why does the same medicine causes side effects in some people while others tolerate it well? In a new study, researchers utilized the Estonian Biobank to provide a more comprehensive picture.

News • From the heart to the brain

Atrial fibrillation: heart rhythm management for stroke prevention

For people hospitalized with ischemic stroke and atrial fibrillation, restoring the heart’s normal rhythm within eight weeks is associated with a lower risk of having another stroke, a study finds.

News • Chemosensory dysfunction

Smell and taste problems after Covid: study investigates impact of vaccines

A Covid infection can affect a person's sense of smell or taste – but what about vaccination? New research investigated smell and taste changes after vaccination – with reassuring results.

News • Cognitive behavioral therapy

AI-enhanced virtual reality could help manage menopause symptoms

A new study suggests that virtual reality (VR) and AI could be an effective tool to help women manage menopause symptoms, including hot flashes, insomnia, depression, and sexual dysfunction.

News • Nuclear medicine

ccRCC kidney cancer: PET/CT imaging approach improves lesion detection

A new PET imaging approach detected 97.9% of lesions in clear cell renal cell carcinoma, potentially giving clinicians a more complete picture of the location and extent of a patient’s disease.

News • Study evaluates effect on patient recovery

Anaesthesia: TIVA or inhalation for major surgery?

Choice of general anaesthetic for major surgery can continue to be based on patient and clinician preference, according to the largest ever trial comparing the two main techniques used in the NHS.

News • Experimental pathology

Predicting which HPV infections will progress to cancer: are we there yet?

In some cases, an HPV infection persists and can develop into precancerous lesions or even cancer. A new study explores how these high-risk situations can be identified at an early stage.

News • Drug-coated balloons as alternative

Many heart patients could avoid permanent stents, study finds

Thousands of heart patients could be treated without having a metal stent permanently implanted in their arteries – according to research from the University of East Anglia.

News • Global and regional burden of CRC

H. pylori may be behind more than one in five colorectal cancer cases worldwide

A study has found that exposure to Helicobacter pylori, a bacterium known to cause stomach ulcers and gastric cancer, may be associated with approximately 22% of colorectal cancer cases globally.

News • Proof-of-concept study

AI platform lets patients communicate with their medical devices

A new AI-driven platform could allow people to interact with their medical devices by sending messages using a smartphone app and receiving feedback in real time.

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