Clinical chemistry has evolved far beyond its beginnings of blood and urine analysis. Advanced techniques such as enzyme measurement, electrophoresis, and immunoassays have made their impact on the field, expanding its diagnostic capabilities. Keep reading for advances in automation and clinical chemistry applications for toxicology, urinalysis and much more.
World TB Day raises awareness about tuberculosis and commemorates the discovery of the source bacterium M. tuberculosis. More than a century later, scientists still refine anti-TB strategies.
Researchers have succeeded in producing sensors from single-wall carbon nanotubes that are suitable for detecting even minute changes in specific substances in the body, such as female hormones.
A new way to inhibit the proliferation of Sars-CoV-2 opens up new perspectives in the fight against this coronavirus and other viral diseases that still have no medical treatment.
Researchers from China have developed ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer.
A US-Swiss team leverages AI and molecular simulations to uncover new pathways for precision cancer treatments, paving the way for more effective, personalized therapies.
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
Researchers were able to package fluorescent sensors for passage across the blood-brain barrier (BBB) in mice. This holds promise to advance Alzheimer’s disease diagnosis and treatment.
Researchers have developed a fluorescence assay for viral integrity (or FAIRY, for short), to quickly determine the effectiveness of countermeasures against a given virus.
A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.
A team of researchers has discovered a new method of measuring levels of cortisol directly from a blood sample - a significant step forward in diagnosis and treatment of a wide range of diseases.
A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against ‘superbugs’ such as MRSA, a new study shows.
What role should artificial life play in medicine? Researchers from Denmark and the US explore the potential of hybrid peptide-DNA nanostructures for diagnosing and treating diseases.
US scientists report using a single-atom-thick nanomaterial to simultaneously detect Covid-19 and flu viruses — at much lower levels and much more quickly than conventional tests for either.
Urine screening tests using only immunoassays are the most common procedures used to identify drug abuse. They are inexpensive, automated, and produce rapid results. But they may generate false-positive or false-negative results, which vary based on the drug, drug class, and the assay used. Hair toxicology analysis is another form of drug testing which, unlike urine tests, enable analysis of drug…
Clinical laboratories need to be proactive to attract transgender patients for testing and to ensure that they are comfortable with the services provided. This issue is of great importance to the American Association for Clinical Chemistry (AACC), which conducted a scientific session on transgender health at its recent annual meeting in Chicago.
Researchers have identified an enzyme that is a promising new therapeutic target to combat the dangerous bacterial disease melioidosis.
Researchers created a special ultrathin sensor, spun from gold, that can be attached directly to the skin without irritation or discomfort. The sensor can measure different biomarkers or substances to perform on-body chemical analysis.
Researchers have shown that aggregation of amyloid-beta, one of two key proteins implicated in Alzheimer’s disease, causes cells to overheat and ‘fry like eggs.’
Liquid profiling is offering clear benefits in terms of cancer diagnostics and targeted therapy, but challenges remain in bringing it into the clinic.
