Keyword: women's health

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ctDNA vs. HGSOC

Taking 'molecular snapshots' of ovarian cancer

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer. The HGSOC tumors consist of several heterogeneous cell populations with a large number of mutations. This genetic variability makes it difficult to find drugs that would kill all the cancer cells, and to which the cells would not become resistant during treatment. Over half of the patients…

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Women's health

Endometriosis: Antibiotic could be key to treatment

Researchers at Washington University School of Medicine in St. Louis have found, in mice, that treatment with an antibiotic reduces the size of lesions caused by endometriosis. The researchers are planning a large, multicenter clinical trial to test the drug metronidazole in women who have the painful condition. The study is published online April 30 in the journal Human Reproduction.…

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PARG inhibitors

New class of drugs could treat ovarian cancer

A team of researchers across The University of Manchester have shown that a new class of drugs are able to stop ovarian cancer cells growing. The Cancer Research UK and Wellcome Trust funded study, published in the journal Cancer Cell, showed that the drugs, called PARG inhibitors, can kill ovarian cancer cells by targeting weaknesses within their ability to copy their DNA. The first-in-class…

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Machine learning tool

AI can predict survival of ovarian cancer patients

Researchers have created a new machine learning software that can forecast the survival rates and response to treatments of patients with ovarian cancer. The artificial intelligence software, created by researchers at Imperial College London and the University of Melbourne, has been able to predict the prognosis of patients with ovarian cancer more accurately than current methods. It can also…

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Oral contraceptives

Can birth control pills keep you from recognising emotions?

The pill could be blurring your social judgement ‒ but perhaps not enough so you'd notice. By challenging women to identify complex emotional expressions like pride or contempt, rather than basic ones like happiness or fear, scientists have revealed subtle changes in emotion recognition associated with oral contraceptive pill (OCP) use. Published in Frontiers in Neuroscience, their study found…

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Breast and skeletal health

AI is proving pivotal in women’s health solutions

Artificial Intelligence (AI) is proving pivotal as Hologic evolves its women’s health solutions. With a focus on breast and skeletal health, future steps will see the medical technology company incorporate a more integrated approach to drive better, more cost effective, outcomes that are clinically supported to deliver an improved patient experience. Pete Valenti, Hologic’s division president…

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Benefits of childbirth

Breast cancer: Pregnancy gives (delayed) protection

In general, women who have had children have a lower risk of breast cancer compared to women who have never given birth. However, new research has found that moms don’t experience this breast cancer protection until many years later and may face elevated risk for more than 20 years after their last pregnancy. Scientists at the National Institutes of Health, along with members of the…

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Pregnancy

Giving birth raises risk of breast cancer in younger women

Younger women who have recently had a child may have a higher risk of breast cancer than their peers of the same age who do not have children, according to a large-scale analysis co-led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher. The findings, published in the Annals of Internal Medicine, may seem contrary to conventional wisdom that childbirth is…

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Birth outcome study

Obesity and pregnancy: A risky couple

New research from the University of Adelaide’s Robinson Research Institute supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant. The researchers have reported the results of a large study of birth outcomes in more than 500 overweight or obese women from three public maternity units in Adelaide, Australia in The Lancet Diabetes &…

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Research

First evidence that soot from polluted air is reaching placenta

Evidence of tiny particles of carbon, typically created by burning fossil fuels, has been found in placentas for the first time, in new research presented at the European Respiratory Society International Congress. Previous research has indicated links between pregnant mothers’ exposure to air pollution and premature birth, low birth weight, infant mortality and childhood respiratory problems.

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Cardiology & the sexes

Why heart attacks are different for women

MRI has a central role in picking up myocardial infarction with non-obstructive coronary disease, a condition that particularly affects women but is often left untreated, with potentially fatal outcome. Heart attack in women presents differently than in men and requires a different approach when it comes to detection and prevention, according to Allison Hays, a cardiologist and assistant…

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Heat therapy

Soaking in a hot tub has unexpected benefits, researchers find

According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…

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Gender differences

Migraines: Why women suffer more frequently

Of the more than 38 million Americans who experience migraine headaches, 28 million are women. Compared to men, women also experience more frequent and severe migraines and don’t respond as well to drug treatments. Findings from a new study conducted in rats reveal that females may be more susceptible to migraines and less responsive to treatment because of the way fluctuations in the hormone…

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Innovative test

Diagnosis of bacterial vaginosis

Bacterial vaginosis (BV) is a common infectious disorder that affects millions of women worldwide. Women of all ages are at risk for BV and its complications, which include a greater susceptibility to sexually transmitted infections (STIs) such as herpes simplex virus and HIV. If left undetected and untreated, BV can increase a woman's risk of upper genital tract infections such as pelvic…

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Women's health

Benign gynaecology specialist centres are needed

The recently opened Uterine Repair Center (URC) in VUmc (Amsterdam) serves women suffering non-cancerous gynaecological disorders, such as myomas, adenomyosis (endometriosis of the uterus), niches (caesarean scar defects) or congenital uterine abnormalities. Gynaecologist Professor Judith Huirne leads the clinic – but has greater aspirations. As a professor of benign gynecology, in her…

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Global partnership

Philips and Hologic team up for women’s health

Royal Philips, a global leader in health technology, and Hologic, Inc., an innovative women’s health company, announced a global partnership agreement to offer care professionals integrated solutions comprising diagnostic imaging modalities, advanced informatics and services for screening, diagnosis and treatment of women across the world. The collaboration combines Hologic’s innovative…

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DIY testing

Self-sampling identifies twice as many women at risk of cervical cancer

Using self-sampling followed by HPV testing, more than twice as many women at risk of developing cervical cancer could be identified and offered preventive treatment. This is shown by researchers at Uppsala University in the first randomised study in the world comparing two ways of identifying cervical cancer, published in the British Journal of Cancer. Cervical cancer screening has previously…

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HPV infections

Cervical cancer awareness

No woman should die from cervical cancer. Indeed, cervical cancer is the deadliest, yet most preventable gynecologic malignancy. According to the American Cancer Society, there are 13,000 new cases of invasive cervical cancer leading to 4,100 cancer-related deaths each year in the United States. Unfortunately, many of these deaths could have been prevented with either regular screening with Pap…

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Risk for pregnancy

How Zika infection drives fetal demise

A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy. When exposed to Zika virus before birth, mouse fetuses with the protein commit cell suicide, while fetuses without it continued to develop. The result, published in Science Immunology, suggests that the protein, a receptor involved in immune cell signaling, plays a role in spontaneous abortions and other human…

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Tumor analysis

Immune response to ovarian cancer may predict survival

A group of international cancer researchers led by investigators from Mayo Clinic and University of New South Wales Sydney has found that the level of a type of white blood cell, called tumor-infiltrating lymphocytes, present in the tumors of patients with high-grade ovarian cancer may predict a patient’s survival. “We know that a type of tumor-infiltrating lymphocyte called cytotoxic CD8 are…

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Women's health

Breast cancer treatment has evolved. Here’s where we are.

There is no “one size fits all approach” when it comes to treating breast cancer. The disease is made up of several subtypes, and ideally each type should be treated with therapies that target the unique underlying biological problems. Fortunately, for the past 25 years, long-term survival and cure rates have significantly improved for women with breast cancer. This is due in large part to…

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