Radiation therapy

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Reducing collateral damage

A shield to protect patients during prostate cancer radiotherapy

Prostate cancer specialists from the Radiotherapy Department at Norfolk and Norwich University Hospitals Foundation Trust have become the first in the world to use an innovative technique to help…

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Personalizing treatment

AI can help improve precision radiotherapy

The Netherlands Cancer Institute, University of Amsterdam (UvA), and Elekta will collaborate on the development of new AI strategies for the further improvement of precision radiotherapy. This…

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Mammacarcinoma study

Breast cancer: finishing treatment soon after diagnosis increases survival

Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation…

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TARGIT-IORT

Pioneering single-dose radiotherapy for breast cancer treatment

A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional radiotherapy, and avoids potential damage to nearby organs, according to a paper by UCL experts.

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Esophagitis

Lung cancer: Tailoring radiation therapy to reduce complications

For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment…

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Combining MRI with particle beams

An important step towards live imaging in proton therapy

Researchers at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) want to build the world’s first prototype that tracks moving tumors with magnetic resonance imaging (MRI) in real time during proton…

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The QuADRANT project

Clinical audits in radiology to promote high quality medical care

Clinical audit within radiology departments can help promote high quality medical care and improve patient experience, as well as provide educational and teaching opportunities. Aiming to see consistent delivery across Europe, clinical audit is currently under the initiative ‘Diagnostic and Interventional Radiology, Radiotherapy, and Nuclear medicine including Therapies’. The latest project…

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Curbing collaterals

High energy radiotherapy ‘paints’ tumours, avoids healthy tissue

A radiotherapy technique which ‘paints’ tumours by targeting them precisely, and avoiding healthy tissue, has been devised in research led by the University of Strathclyde. Researchers used a magnetic lens to focus a Very High Electron Energy (VHEE) beam to a zone of a few millimetres. Concentrating the radiation into a small volume of high dose will enable it to be rapidly scanned across a…

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"InnerEye" Artificial Intelligence

AI could help cut waiting times for cancer radiotherapy

Doctors at Addenbrooke’s Hospital in Cambridge aim to drastically cut cancer waiting times by using artificial intelligence (AI) to automate lengthy radiotherapy preparations. The AI technology, known as InnerEye, is the result of an eight-year collaboration between researchers at Cambridge-based Microsoft Research, Addenbrooke’s Hospital and the University of Cambridge.

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AI-assisted MRI segmentation

Deep learning boost for prostate cancer workflow

Prostate cancer radiotherapy treatments guided by MRI are increasingly being explored to help improve patient outcomes and reduce toxicities after treatment. However, this development is being held back as the MRI approach is labour intensive and requires daily adaptive treatment planning, placing significant additional demands on clinician time and oncology services. To address this, a team of…

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Dosimetry solution for radiotherapy

Automating patient QA with advanced 3D EPID dosimetry

Dosimetry specialist PTW Freiburg GmbH signed a collaboration agreement with The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital (NKI-AVL, Amsterdam) to jointly develop an advanced EPID-based dosimetry solution for automated patient-specific quality assurance in radiotherapy. The new software module RT EPID, which will become part of PTW’s patient QA platform Veriqa, builds on…

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Dose calculation

Cooperation to improve patient-specific QA in radiotherapy

The dosimetry specialist PTW Freiburg GmbH has entered into a collaboration with the US-based bioinformatics company Radialogica LLC to integrate their advanced SciMoCa Monte Carlo dose calculation algorithm into PTW’s patient QA platform Veriqa. The new Veriqa module RT MonteCarlo 3D, which uses the SciMoCa dose engine for calculation-based radiotherapy plan verification, has received CE mark…

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TARGIT-IORT vs. EBRT

Breast cancer radiotherapy: A single dose is often enough

For most women with early breast cancer, a single dose of targeted radiotherapy during surgery is just as effective as conventional radiotherapy, which requires several visits to hospital after surgery. This combination of targeted radiotherapy (restricted to the area around the tumour) given immediately after surgery is called targeted intraoperative radiotherapy. Conventional radiotherapy…

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Cancer radiotherapy monitoring

Novel hydrogel turns pink to indicate radiation dose sweet spot

More than half of all cancer patients undergo radiation therapy and the dose is critical. Too much and the surrounding tissue gets damaged, too little and the cancer cells survive. Subhadeep Dutta and Karthik Pushpavanam, graduate students working in the lab of Kaushal Rege, Professor at Arizona State University in Tempe, and collaborators at Banner-M.D. Anderson in Gilbert, Arizona, developed a…

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Hyperventilation vs cardiac arrhythmia

Hold your breath – save your heart?

A technique that enables patients suffering from heart conditions to hold their breath safely for over 5 minutes could have potential as part of a new treatment for cardiac arrhythmias, say researchers at the University of Birmingham. In a new study, published in Frontiers in Physiology, researchers initially proposed the technique as a new means for earlier diagnosis of ischaemic heart disease.…

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The future has begun

Cancer care 2035: multi-disciplinarity is key

An enthralling insight into the care that could be offered to cancer patients of the future was presented by cancer imaging expert Professor Regina Beets-Tan during her a keynote presentation at the recent British Institute of Radiology congress. In the session ‘Oncologic imaging: Future perspectives’, the professor outlined what a Multi-Disciplinary Team (MDT) of the future – a team in…

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Today’s improved lower leg treatments

Peripheral vascular therapies

Interventional radiotherapy for tibial arteries has increased in recent years. Why? People are getting older and better techniques and materials now permit treatment even of very thin vessels. Professor Dierk Vorwerk, Director of the Institute for Radiology at Ingolstadt Hospital, where almost a third of all interventions in his department are performed on the lower leg, described the most…

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Targeted therapy for pancreatic carcinoma

Hitting cancer with 'homing' radioactive molecules

Pancreatic cancer is one of the leading causes of cancer‑related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects. In a collaborative research between Osaka University and the University of Heidelberg, researchers are exploring a new method of treatment that brings powerful yet…

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Radiology research

Tuned X-rays for safer, more precise cancer radiation therapy

X-rays could be tuned to deliver a more effective punch that destroys cancer cells and not harm the body, researches from Kyoto University find. Gadolinium delivered into cancer cells releases killer electrons when hit by specially tuned X-rays. The approach, published in the journal Scientific Reports, could pave the way towards a new cancer radiation therapy. “Our method opens up the…

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Stem cell regeneration

Drug accelerates recovery after chemo, radiation

A drug developed by US physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants. The study, published in Nature Communications, also sheds light on the basic biology behind blood…

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Dose reduction

Increasing precision for radiotherapy

A new way of concentrating radiotherapy dose in tumours, while minimising damage to healthy cells, has been proposed in research led by scientists at the University of Strathclyde. The study proposes that focusing high-energy particle beams on a small spot deep inside the body could potentially enable clinicians to target cancerous tumours precisely, while reducing the dose to surrounding tissue.…

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Interdisciplinarity

All for one: a Belgian prostate unit at work

Pathologists, radiologists, urologists and radiotherapy specialists sit at the core of the treatment pathway for the patient, working together as a cohesive unit. In an innovative 2019 ECR session in Vienna, the prostate unit from Ghent University Hospital in Belgium outlined how the team works to deliver the best clinical outcome for patients. Session chair Professor Geert M Villeirs of Ghent…

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