Diagnostics

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Diagnostic

Potential therapeutic target for lung cancer

Scientists reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell death regulator (LCDR) in tumor survival, providing a potential diagnostic and therapeutic…

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Autohaem smear and smear+

Automating blood smears for malaria diagnosis

Researchers have developed a device that removes one of the biggest bottlenecks preventing quick, reliable malaria diagnosis.

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Sponsored • Chemistry & immunochemistry

Fujifilm Wako – Autokit CH50 Assay

Autokit CH50 Assay is an in vitro diagnostic (IVD) test for the quantitative determination of total complement activity in human serum. The complement system is a part of the immune system that…

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Glioblastoma

Blood test for brain tumors possible

Researchers at the University of Sussex are one step further to developing a blood test capable of diagnosing the most aggressive form of brain tumour.

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Research

Quantum sensor to detect SARS-CoV-2 faster

Scientists at have designed a quantum sensor to detect SARS-CoV-2 faster, cheaper, and more accurate than the current gold-standard technique, PCR.

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Intelligent algorithms

The gait lab for the pocket – app-based fall prevention

Every day, elderly people fall – be it at home or in care facilities. Med-tech start-up Lindera developed an app that allows motion analysis via a smartphone camera to minimize the risk of falling.

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Conducting diagnostics

Detecting breast cancer via electrical currents in the skin

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation. While the risk of getting breast cancer is higher for older people, it can strike at any age. Studies show that 5% to 7% of females with breast cancer…

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Diagnostic advance

New AI assisted device could soon replace traditional stethoscope

A stethoscope is one of a doctor's most important instruments, but there haven't been any fundamental improvements in the device itself since the 1960s. Now, researchers at Aalto University have developed a device that analyses a broad range of bodily functions and offers the doctor a probable diagnosis, as well as suggestions for appropriate further examinations. The researchers believe that the…

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New EU regulation

Lab tests: Watch out! Conflict ahead

In May 2022 a shortage of several lab tests may come as many manufacturers struggle to comply with EU regulation requirements covering in vitro diagnostic medical devices (IVDR, Regulation (EU) 2017/746). Even modified tests and laboratory-developed tests will present a problem for hospitals and labs as explained by Dr Thomas Streichert.

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Coronary microcirculation

New measurements improve diagnosis of ‘woman’s heart’

Researchers at the Catharina Heart and Vascular Center, together with Eindhoven University of Technology, have developed a new measurement method to analyze the smallest capillaries of the heart by measuring blood flow and resistance. The new method to assess coronary microcirculation allows cardiologists to make a clearer diagnosis. Until recently, the tests used for this purpose were not…

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Rapid detection

Molecular diagnostic test for Covid-19, Flu, RSV receives CE mark

A new rapid molecular diagnostic test from Cepheid has received the CE mark for distribution in the European market. The test, called Xpert Xpress CoV-2/Flu/RSV plus, is designed for qualitative detection of the viruses causing Covid-19, Flu A, Flu B, and respiratory syncytial virus (RSV) infections from a single patient sample. The new plus version of the test provides a third gene target for…

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Histological grading assistance

AI improves precision in breast cancer diagnosis

Researchers at Karolinska Institutet have developed an AI-based tool that improves the diagnosis of breast cancer tumours and the ability to predict the risk of recurrence. The greater diagnostic precision can lead to more personalised treatment for the large group of breast cancer patients with intermediate risk tumours. The results are published in the scientific journal Annals of Oncology.

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Discussing benefits and flaws

AI in cardiology: a marriage made in heaven – or hell?

The role of Artificial Intelligence (AI) is one of the most divisive issues in cardiology. Two leading experts argue the pros and cons of its use, exploring its benefits and advantages to cardiac care, as well as highlighting the pitfalls and shortcomings of AI, while underlining the need for clear guidelines and regulations for its use going forward.

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Experts on new IVD regulation

"We predict the loss of a large number of critical diagnostics"

MedTech Europe, the European trade association for the medical technology industry including diagnostics, medical devices and digital health, ran a survey in July 2021 to gather data from IVD manufacturers on the state of the IVD market today and how they are expected to transition to the IVD Regulation within ten months from the survey date. The survey, which represents an estimated 90% market…

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Search for signatures

‘Long Covid’ biomarkers in blood could lead to diagnostic test

Markers in our blood – ‘fingerprints’ of infection – could help identify individuals who have been infected by SARS-CoV-2, the coronavirus that causes Covid-19, several months after infection even if the individual had only mild symptoms or showed no symptoms at all, say Cambridge researchers. The team has received funding from the National Institute for Health Research to develop a test…

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Oncology

Pancreatic cancer - current challenges and future direction

Pancreatic cancer is one of the deadliest cancers in the world, and one of the most difficult to treat. In 2020, an estimated 495,000 individuals worldwide were diagnosed with pancreatic cancer and an estimated 466,000 died, according to statistics from the World Health Organization’s International Agency for Research on Cancer. Most patients with advanced disease die within a year of…

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