Oncology

News • Circulating tumor extracellular vesicles

Metastatic prostate cancer: better monitoring with new liquid biopsy method

A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.

Article • Benefits of seated placement

Patient positioning during cancer radiotherapy: Upright is alright

The concept of delivering radiation therapy to cancer patients seated in an upright position is undergoing a major resurgence. Evidence is already highlighting that patients feel more comfortable…

News • Reduction of greenhouse gas emissions

Telemedicine for more sustainable cancer care

Cancer care that utilizes telehealth and local care would generate 33.1% less greenhouse gas emissions than the traditional model, new research finds.

World's First Total-Body PET/CT with 194 cm Axial FOV installed in Europe

The IRCCS in Bologna has inaugurated a state-of-the-art integrated PET/CT system. This cutting-edge technology allows for the entire human body to be studied in a single scan, even detecting the…

News • Foetal development research

Tracing back the origins of AML childhood leukaemia

Acute myeloid leukaemia (AML) is a common type of blood cancer in childhood and can be diagnosed within a few months of life. New research shows that its origins can be traced back to before birth.

News • Success of aRCC treatment

New biomarker to better predict immunotherapy response in kidney cancer

Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.

News • Noninvasive stratification

Multiplex PET helps doctors 'see' bowel cancer

Multiplex PET imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, according to scientists in Glasgow.

News • Chemotherapy and novel surgery technique

Study explores new approach to 'inoperable' pancreatic cancer

US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.

News • Voxel-wise classification

Deep learning tool uses MRI to enhance brain tumor diagnosis

A novel AI-based, non-invasive diagnostic tool enables accurate brain tumor diagnosis, outperforming current classification methods. The tool leverages MRI information to aid clinical decision making.

News • Personalised oncology

New platform to significantly reduce cancer drug testing and screening time

In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.

News • Appeal for better approval conditions

AI in personalised cancer medicine: “A fundamental change is needed”

AI technology holds promise for personalised cancer therapies. However, rigid and slow approval requirements impede its introduction, say experts – and point out how this might be changed.

News • CTC, ctDNA and exosomes in PCa management

Prostate cancer: Blood-based liquid biopsies yield valuable information

US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.

News • Friend and foe in one

Breast cancer: The paradoxical role of white blood cells

White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.

News • Encouraging results of DARS trial

A ‘new gold standard’ for head and neck cancer radiotherapy

New research suggests a new approach to precision radiotherapy can reduce the risk of swallowing problems for patients, without impacting the success of treatment.

News • Interaction with cancer patients

Experts raise ethics concerns posed by patient-facing AI in oncology

Bioethics researchers call on medical societies, government leaders, clinicians, and researchers to work together to ensure AI-driven healthcare preserves patient autonomy and respects human dignity.

News • IC before CRT

Cervical cancer: Improved treatment course increases survival, reduces recurrence

New trial results suggest that a short course of induction chemotherapy prior to chemoradiation could reduce the rate of relapse and death among patients with locally advanced cervical cancer.

News • Supportive communication reduces uncertainty

One of clinicians' mightiest weapons against breast cancer? Empathy

Clinicians who show more empathy promote better psychological health among breast cancer patients, according to a new US study examining how oncology doctors facilitate psychological well-being.

News • Radiation and immunotherapy

Promising combination therapy against "cold" breast cancer tumors

US researchers have discovered that radiation therapy combined with two types of immunotherapy can control tumors in preclinical models of triple negative breast cancer.

News • Biomarker-based predictions

AI drives precision oncology for colorectal cancer

For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).

News • Patchy recommendations

Errors and half-truths plague cancer treatment plans generated by ChatGPT

Experts from Brigham and Women’s Hospital have tasked ChatGPT to generate recommendations for cancer treatment – with some promise, but ultimately inadequate results.

News • Biopharmaceutical business

Precision approach to significantly reduce R&D costs for cancer drugs

A new analysis exploring the finances of bringing new cancer drugs to market has found that precision oncology drugs could be $1 billion cheaper to develop than non-precision drugs.

Article • RFA, MWA, CRYO and IRE under scrutiny

Thoracic interventions: new tools in the arsenal

Experts presented state-of-the-art and emerging techniques to treat chest tumours and discussed common issues in the management of pneumothorax at RSNA 2022. Current ablation methods in the thorax include radiofrequency ablation (RFA), microwave ablation (MWA), cryoablation (CRYO), irreversible electroporation (IRE) and pulsed electric field.

Article • Oncology imaging

The expanding role of CT in lung cancer management

While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.

News • Precision oncology

Genomic sequencing benefits only 5% of cancer patients

Genomic sequencing panels as part of personalised cancer treatment have been found to only benefit one in 20 patients they are currently used for, according to a study by CNIO.

Article • Cancer patients at risk

Blood test detects risk of neurotoxicity from CAR T-cell therapy

Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…

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