Oncology

News • Potential of immunotherapy explored

Surgery first for colon cancer? Not so fast, says new study

Immunotherapy prior to surgery is surprisingly effective for patients with a certain type of colorectal cancer (dMMR/MSI-H CRC). These new study results contrast current treatment regimens.

News • Hereditary non-polyposis colorectal cancer

Lynch syndrome: AI improves colorectal cancer screening

Researchers have now found that artificial intelligence (AI) can improve the effectiveness of colonoscopy in the presence of Lynch syndrome.

News • Patient-derived whole-tumor cell culture model

Breast cancer: New method finds the right therapy

Swedish researchers have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not.

News • Prevalence of metastatic BRCA

New research shows scale of secondary breast cancer in England

A cancer researcher and consultant has estimated for the first time how many women are living with secondary breast cancer in England – in new research which could help to shape cancer services.

News • Prolonging life vs. maintaining functionality

Cancer treatment goals: patients and doctors often not on the same page

Prolonging life may not be a top priority for everyone: New research finds that patients with neuroendocrine tumours and their doctors often disagree when it comes to treatment goals.

Article • Mid-treatment scans can reduce treatment sessions

De-escalating radiation therapy for oropharynx cancer with FDG-PET

Using fluorodeoxyglucose positron emission tomography (FDG-PET) imaging may give insights into possible dose reductions in ongoing radiation therapy of head and neck cancer. A promising study to…

News • Precision medicine

Localising BRCA gene mutations to better treat ovarian cancer

An international team highlights the importance of localising BRCA1 and BRCA2 gene mutations for the treatment of ovarian cancer.

Article • AI-based personalized medical care

I³lung: EU launches lung cancer initiative

This summer, The European Commission launched I3lung, a new research initiative as a part of Horizon Europe, the EU’s research and innovation program. This research initiative aims to create a cutting-edge, decision-making tool to help clinicians and patients select the best lung cancer treatment based on each patient’s specific needs and circumstances.

News • Oncology forecast

Is Europe facing a 'cancer epidemic' in the next decade?

With an estimated one million cancer diagnoses missed across Europe in the last two years, the impact of the Covid-19 pandemic is predicted to set back European cancer outcomes by almost a decade.

Article • Early detection approach

Multi-cancer blood tests could shake up screening

New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer early detection (MCED) tests in development can spot common cancer signals and predict where the signal comes from in the body, results from a prospective investigation suggest.

Article • Visceral imaging

Endosonography: AI takes on the “supreme discipline”

Endosonography poses unique challenges for medical professionals, because two demanding disciplines have to be mastered at the same time. The use of artificial intelligence (AI) could help speed up the notoriously slow learning curve of the procedure, says Prof Dr Christoph F. Dietrich. At the Visceral Medicine Congress in Hamburg, the expert explained how AI can help endosonography achieve…

News • Stereotactic body radiotherapy

Advanced radiotherapy speeds up prostate cancer treatment

An advanced radiotherapy technique can be used to safely treat prostate cancer patients in as little as one to two weeks, compared with the current standard, which takes one to two months.

News • Nasopharyngeal cancer study

Covid vaccination improves effectiveness of cancer treatment

Until now, it was feared that vaccination against Covid-19 could reduce the success of treatment for patients with nasopharyngeal cancer. A recent study now gives the all-clear in this regard.

News • Equivalent outcomes in 5 vs 8-week treatment

High-risk prostate cancer: Study confirms effectiveness of shortened radiation therapy

A new randomized study confirms that men with high-risk prostate cancer can be treated with a moderately shortened course (5 vs. 8 weeks) of radiation therapy.

News • Possible biological explanation found

Why are dense breasts associated with increased cancer risk?

The risk of developing breast cancer is higher in breasts with high density. But why is that? Researchers at Linköping University have shown major biological differences that promote cancer growth.

Video • Digital patient support tool

Ovarian cancer: "Olivia" to provide information and support

Patients affected by ovarian cancer can turn to "Olivia": The interactive digital resource provides information about diagnostics, treatment and life with ovarian cancer.

Malignant tumour management

’Our machine learning model achieved 88.9% accuracy in predicting the sarcoma-specific survival rate’

Clinical management of soft tissue sarcoma is particularly challenging. Dr Sebastian Foersch, researcher at the Institute of Pathology at the University Medical Center in Mainz, Germany, has used a deep learning model for diagnosis and prognosis prediction of soft tissue sarcoma using conventional histopathology slides.

Article • Patient care

Molecular Tumour Board for better decision-making

As more genomic alterations become targets for therapy, health institutions and hospitals are creating specialist Molecular Tumour Boards to support better decision-making for patient care. This evolving team, and its role, was highlighted in a presentation at the 34th European Congress of Pathology in Basel, Switzerland.

News • Researchers develop noninvasive approach

FUSIN: Delivering gene therapy with ultrasound

Treatment of central nervous system diseases and tumors is often hindered by the blood-brain barrier. A new method aims to overcome this obstacle using focused ultrasound intranasal delivery (FUSIN).

News • New study

Can physical exercise enhance the effect of chemotherapy against breast cancer?

Many women diagnosed with breast cancer can be cured with surgery, radiotherapy and medical treatment. Swedish researchers explore whether physical exercise can support the anti-tumour effects.

Article • Interpreter of maladies

Will AI help realize the promise of precision medicine?

Machine learning and artificial intelligence (AI) have the potential to transform cancer treatment management worldwide. Their ability to rapidly analyse and integrate routinely acquired diverse data will improve the accuracy and effectiveness of precision medical treatments.

News • Imaging AI

Photon-counting CT improves myeloma bone disease detection

New CT technology paired with artificial intelligence-based noise reduction offers superior detection of bone disease associated with multiple myeloma at lower radiation doses than conventional CT.

News • Precision oncology

What's new in cancer therapy?

Researchers from the University of Bern and Inselspital provide an overview of the latest technologies in precision oncology. Translating these into clinical application is still a major challenge.

News • Relapse rate research

Breast cancer: Fertility preservation measures do not increase recurrence risk

A new study shows that women with a breast cancer diagnosis undergoing procedures for fertility preservation are not at increased risk of recurrence of the disease or disease-specific mortality.

News • High-glade glioma research

Understanding why deadly brain cancer comes back

A surprising mechanism explains why high-grade gliomas, the deadliest form of brain cancer, returns: The tumours adapt to treatment by recruiting help from nearby healthy tissue.

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