Keyword: molecular

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No more joint replacement?

Small molecule could make a big difference for arthritis patients

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic. In a new publication in the Annals of Rheumatic Diseases, Evseenko’s team describes the promise of a new molecule aptly named “Regulator of Cartilage Growth and Differentiation,” or RCGD…

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Primary ciliary dyskinesia

Molecular roots of genetic lung disease identified

Respiratory infections peak during the winter months, and most people recover within a few weeks. But for those with a rare genetic lung disease, the sniffling, coughing and congestion never end. The tiny hairlike structures called cilia that normally sweep mucus through the airways don’t work properly in people with what’s known as primary ciliary dyskinesia. When the cilia don’t brush…

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Gene editing

CRISPR system embeds images in DNA

A research team in the United States has developed a revolutionary technique that has encoded an image and short film in living cells. Scientists at the Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) used CRISPR gene editing to encode the image and film in DNA, using this as a medium to store information and produce a code that relates to the individual…

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Sugar molecules

Sweet help for cancer detection

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner.

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Molecular mechanisms

The key to growing new arteries

Arteriogenesis is a critical event – not only during development but also in adult life. Many Cardiovascular life-threatening events could be overcome by inducing the formation of new arteries. A team of scientists led by Ralf Adams from the Max Planck Institute for Molecular Biomedicine has developed a genetic approach in mice to uncover molecular mechanisms of arterial growth.

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It's dangerous to go alone

Why social isolation can bring a greater risk of illness

Social isolation has been linked to a wide range of health problems, as well as a shorter lifespan in humans and other animals. In fact, during a U.S. Senate hearing on aging issues this spring, a representative for the Gerontological Society of America urged lawmakers to support programs that help older adults stay connected to their communities, stating that social isolation is a “silent…

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Strategic cooperation

SpeeDx and Cepheid announce partnership on European distribution

SpeeDx Pty, Ltd. announced an agreement with Cepheid for distribution of its PlexPCRTM and ResistancePlusTM molecular diagnostic products in key markets throughout Europe. The agreement, covering Germany, France, Italy, and the UK, will increase coverage for the market-leading ResistancePlus MG test, the first CE-IVD test for Mycoplasma genitalium to combine detection with testing for…

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Ophthalmology

Potential predictor of glaucoma damage identified

Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, there’s no way to accurately predict which patients might lose vision most rapidly. Now, studying mice, rats and fluid removed from the eyes of patients with glaucoma, researchers at…

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Lateral flow immunoassay

Up to 10-fold increase in assay sensitivity

BBI Solutions has launched Morffi, a novel conjugate blocking technology that enhances signal intensity and improves the sensitivity of lateral flow immunoassaysThe technology, developed in-house by BBI Solutions scientists, improves the limit of detection of an assay, providing an increase in sensitivity of up to ten times and a faster time to result.

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Microscopy

Watching molecular machines at work

When one cell divides into two - that is how all forms of life are propagated - the newly born daughter cells have to be equipped with everything they will need in their tiny lives. Most important of all is that they inherit a complete copy of the genetic information from their mother cell. If this is not the case because a wrong number of chromosomes – on which the genetic information is…

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Individual treatment

Molecular sub-groups in early stages of bladder cancer

Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed. For many years, this patient group will be examined frequently and during this time many get new tumours; some cases develop aggressively making it necessary to remove the bladder or receive…

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25 Tesla

Switzerland winds up superconductivity

The unusual electronic properties of some superconducting materials permit lossless and dense electrical currents at very low temperatures, even in high magnetic fields. Conductors made of these materials are thus ideal for winding coils to generate very high magnetic fields, which are essential for a number of applications like magnetic medical imaging, MR spectroscopy for the analysis of…

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