Molecular

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News • Focus on AMPA receptor density

Molecular basis of Long Covid's “brain fog” uncovered

New insights on the mechanisms that cause “brain fog” in Long Covid patients: Researchers use a specialized brain imaging technique to identify a potential biomarker and therapeutic target.

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News • Virology

HIV genome integration mechanism decoded by German researchers

German researchers discover how HIV selects genome integration targets using RNA:DNA hybrids as guides, revealing new therapeutic approaches for controlling viral reservoirs.

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News • Prediction of treatment sensitivity

Personalising prostate cancer treatment through molecular testing

A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.

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News • Pharmaceutical counterfeiting

New chemical approach to combat illegal medicines

Pharmaceutical counterfeiting remains a critical issue, with high risks for patients and great economical damage. Now, researchers propose using “chemical fingerprints” to identify illegal meds.

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News • Precision medicine

Melanoma: with 43,000 data points to tailored treatments

Using nine different molecular biological technologies, researchers were able to precisely measure the properties of a melanoma tumor in four weeks and enable a precise treatment decision.

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News • Post-transplant care

Improving heart transplant monitoring with molecular tests

Molecular testing provides a more convenient, personalized way of monitoring of heart transplant recipients, according to insights shared at the Annual Meeting and Scientific Sessions of the ISHLT.

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Article • Molecular meets digital

Single-cell multiplex imaging: a powerful tool for digital pathology

Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…

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Article • Challenges and opportunities

Molecular pathology in Europe: in search of standardization

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.

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