Molecular

News • Post-transplant care

Improving heart transplant monitoring with molecular tests

Molecular testing provides a more convenient, personalized way of monitoring of heart transplant recipients, according to insights shared at the Annual Meeting and Scientific Sessions of the ISHLT.

News • Paediatric research

Molecular ‘fingerprint’ of long Covid in children's blood discovered

A new study has shown that the molecular signature of long Covid can be found in blood samples of children. Using an AI tool, the researchers were capable of diagnosing the condition with 93%…

Article • Between good practice and financial pitfalls

Delivering molecular pathology at lower costs

Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.

News • Reducing chemotherapy side effects

Trapping cancer cells in molecular 'cages'

Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.

News • Synthetic nanofibers

Repairing cartilage damage with ‘dancing’ molecules

US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.

Article • Challenges and opportunities

Molecular pathology in Europe: in search of standardization

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it…

News • Neuropathology

Technology offers new insights into pediatric brain tumors

A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

News • Characterization of cancer relevant genes

Breast cancer: Researchers take a deep dive into cell lines

Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.

News • Molecular machines

Killing cancer cells: the 'jackhammer' approach

Using a unique new technique, US researchers hope to offer a safer and more effective alternative to current cancer treatments, reporting promising first results in mice.

News • Preparing for the next pandemic

New rapid electronic diagnostic test for infectious diseases

A new molecular test for bacteria and viruses, including Sars-CoV-2, has been developed at the University of Surrey, as they warn that the world needs to be prepared for the next pandemic.

News • Molecular and immunofluorescence imaging

Orion: A new tool for diagnosing cancer

Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.

News • Tumor location as important growth factor

New molecular microscopy uncovers breast cancer spread

Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumour may be the key to controlling the spread of disease.

Pluslife Biotech – Mini Dock POC Molecular System

The Pluslife Mini Dock System is a Next-Generation POC molecular diagnostic tool that can be used in different application scenarios, which aims to help the decentralization of MDx in diagnosing facilities.

The Global Alliance for Diagnostics Sets Next-Generation POC Molecular Testing Collaboration

The coronavirus pandemic is a huge challenge for global public health and welfare. Decentralized, affordable POC MDx platforms would allow more effective control of SARS-CoV-2 and other infections.

Article • Patient care

Molecular Tumour Board for better decision-making

As more genomic alterations become targets for therapy, health institutions and hospitals are creating specialist Molecular Tumour Boards to support better decision-making for patient care. This evolving team, and its role, was highlighted in a presentation at the 34th European Congress of Pathology in Basel, Switzerland.

News • Tumor identification in CUP patients

Cancer of unknown primary: comprehensive molecular analysis can improve therapy

A considerable proportion of patients suffering from cancer of unknown primary (CUP) could benefit from comprehensive molecular analysis and molecularly-informed targeted therapies.

News • AI approach to colorectal tumors

Deep learning identifies molecular patterns of cancer

A new AI platform can analyze genomic data extremely quickly, picking out key patterns to classify different types of colorectal tumors and improve the drug discovery process.

Revolutionising Molecular Diagnostics With PurePrep TTR

With micro-organisms and viruses constantly developing, mutating, and evolving, diagnostics must adapt just as rapidly. Advanced laboratory technology and instruments are undeniably a prerequisite for best practice in life sciences and biotechnology.

Molecular scalable solutions for laboratories of every size

One size does not fit all when it comes to diagnostics. Different diagnostic locations need solutions that meet their needs, whether for on-demand testing in a healthcare setting or a laboratory managing population screening. Finding the right solution can be a challenge especially when the future may change what a laboratory needs, Hologic Inc. reports.

News • Rapid detection

Molecular diagnostic test for Covid-19, Flu, RSV receives CE mark

A new rapid molecular diagnostic test from Cepheid has received the CE mark for distribution in the European market. The test, called Xpert Xpress CoV-2/Flu/RSV plus, is designed for qualitative detection of the viruses causing Covid-19, Flu A, Flu B, and respiratory syncytial virus (RSV) infections from a single patient sample. The new plus version of the test provides a third gene target for…

News • A new tool to combat superbugs

Defeating antibiotic resistant bacteria with 'molecular tweezers'

Antibiotic resistant bacteria are a looming super threat – heralding a time when our drugs will no longer be effective against prevalent infections. Hospitals are already coping with treatment-resistant bacterial infections. Cognizant of the threat and thinking outside the box, BGU scientists and German and American colleagues have developed a pair of 'molecular tweezers' to destroy the biofilm…

News • Intrahepatic cholangiocarcinoma

A new approach for treating bile duct cancer

Intrahepatic cholangiocarcinoma (ICC) develops within the liver. With one to two cases per 100,000 inhabitants in Germany, ICC is one of the rare diseases overall, but it is the second most common liver cancer. The aggressive bile duct tumour remains clinically inconspicuous for a long time, so that it is often only detected late. Because the tumour also only responds to chemotherapy to a limited…

News • Potential for rapid, accurate glycan sequencing

Enormous boost for sequencing key molecules

Using a nanopore, researchers have demonstrated the potential to reduce the time required for sequencing a glycosaminoglycan — a class of long chain-linked sugar molecules as important to our biology as DNA — from years to minutes. Research to be published this week in the Proceedings of the National Academies of Sciences shows that machine-learning and image recognition software could be…

News • Entering the oncology growth market

Hologic to acquire molecular diagnostics company Biotheranostics

Hologic, Inc. has announced that it will acquire Biotheranostics, Inc., a privately held, commercial-stage company that provides molecular diagnostic tests for breast and metastatic cancers, for approximately $230 million, subject to working capital and other customary closing adjustments.

News • 3-D analysis

RNA molecules in high resolution

University of Maryland scientists have developed a method to determine the structures of large RNA molecules at high resolution.

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