Lung

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Wako β-glucan test

Better detection and diagnosis of fungal infections

Beta-glucan tests are proving to be pivotal in the better detection and diagnosis of fungal infections. As a robust complimentary test for traditional testing techniques and biomarkers, it is helping…

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Research collaboration

'Cells of the future' might cure lung infections

Healing the body with cells – this is the ambitious goal of scientists at Hannover Medical School (MHH). With this in mind, Professor Dr. Nico Lachmann and Dr. Robert Zweigerdt have initiated a…

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Fight against COVID-19

AI lung scan analysis rolled out across Europe

The Belgian initiative icovid, which supports radiologists in the assessment of CT images of the lungs of COVID-19 patients, has grown into a multicentre European project, co-funded by the EU Horizon…

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Intensive care

Protecting lungs from ventilation-induced injury

An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is likely to cause further lung…

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Lasts longer, causes more damage

Covid-19 pneumonia: not your typical garden-variety pneumonia

Bacteria or viruses like influenza that cause pneumonia can spread across large regions of the lung within hours. In the modern intensive care unit, these bacteria or viruses are usually controlled…

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Dangerous immune response

New insight on severe virus attacks on the lungs

In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet describe how different kinds of immune cells, called…

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Coronavirus imaging

Covid-19: Is CT more sensitive than PCR testing?

Covid-19 causes characteristic changes in lung tissue visible in CT scans and chest radiographs. The “ground-glass” opacities are sharply delineated areas, bilateral and mainly located in the basal and peripheral lung sections. In the course of the infection, the opacities become increasingly consolidated. In the first wave of the Covid-19 pandemic, when PCR tests (RT-PCR) were scarce and had…

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The role of chest CT in diagnosis and treatment

UPDATE: Covid-19 and lung infections imaging

RSNA 2020: International experts showcased new studies on chest CT’s role in Covid-19 diagnosis and treatment. A staggering volume of work and has been produced on the pandemic this year, with an average 367 Covid-19 journal articles published per week, according to Michael Chung, Assistant professor of radiology at Icahn School of Medicine at Mount Sinai, NYC.

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The most compact .55-T full body scanner

Lungs plus A&E MRI scans – no problem

Low, light and with a field strength: 0.55-tesla with added new digital technologies. Indeed, this is a very new class of MRI scanner created by Siemens Healthineers. We interviewed Christiane Bernhardt, Vice President of Magnetic Resonance Marketing & Sales, Business Line MR, at Siemens Healthineers, about the technologies behind this development, plus its advantages and applications.

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Point-of-Care ultrasound

Diving deep with POCUS

Costantino Balestra, Professor of Physiology at Haute Ecole Bruxelles-Brabant in Belgium, uses point-of-care ultrasound (POCUS) in environments that could not be more different from a typical hospital setting. His expertise lies in studying the effects of extreme conditions on the human body, including temperatures, altitudes, and ambient pressures, for example, in deep oceans. One of his areas…

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Using artificial lungs

How COVID-19 causes blood clots

Scientists at EPFL are using technology to better understand how coronavirus causes blood clots in some patients. They have developed a simplified model of a lung that lets them observe, for the first time, how the virus attacks the cells lining blood vessels.

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Nitrogen dioxide levels

Air pollution linked to higher COVID-19 mortality

Scientists have unearthed a possible link between the severity of COVID-19 and air quality. The preliminary study – looking at whether areas with higher levels of air pollutants in England are associated with a larger number of cases/deaths from COVID-19 – was conducted by a team from the University of Cambridge. Aware of the effects that air pollutants have on human health – and that…

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Lung disease burden

New research doubles estimate for COPD prevalence

Around 550 million people have chronic obstructive pulmonary disease (COPD), according to two University of Manchester medical students. The figure more than doubles the previous estimate of 251 million people with the illness linked to smoking by the World Health Organization (WHO) Global Burden of Disease Study. The University of Manchester students, Emily Hammond and Charles McDonald, made the…

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Modality comparison

COVID-19 imaging: lung ultrasound vs chest CT

A recent preprint study in France underpins the debate on whether lung ultrasound (LUS) should be used to triage COVID-19 patients better at the hospital as well as in primary care. The eChoVid study, published as a preliminary report of work on medTrix, shows that LUS enables identification of lung lesions as well as chest CT in COVID-19 patients. A team of French researchers compared routinely…

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Improved accuracy and efficiency

AI could improve CT screening for COVID-19

Researchers at the University of Notre Dame are developing a new technique using artificial intelligence (AI) that would improve CT screening to more quickly identify patients with the coronavirus. The new technique will reduce the burden on the radiologists tasked with screening each image. Testing challenges have led to an influx of patients hospitalized with COVID-19 requiring CT scans which…

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Re-evaluation of the coronavirus disease

COVID-19: A tale of two conditions

The SARS CoV-2 virus which causes COVID-19 may have been named prematurely. As more has become known about the infection, the severe disease does not appear to be a respiratory syndrome at all. Patients who only have a respiratory illness tend not to have a severe condition, while patients who develop a severe condition tend to have non-respiratory conditions, primarily thrombotic or hyper-immune…

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Coronavirus in radiology

Why we need a global view of COVID-19

There are major complications from COVID-19 – ARDS, pulmonary embolism and neurological – that imaging can help detect, manage and/or follow up in the long term, radiologists from France and the UK explained during a recent ESR Connect session. ARDS is the most dreaded complication and the number one morbidity in COVID-19 patients. The incidence was up to 30% of patients in initial reports.…

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Heart failure monitoring

App detects fluid in the lungs via voice recordings

Voice analysis by a smartphone app identifies lung congestion in heart failure patients, allowing early intervention before their condition deteriorates. The small study is presented on HFA Discoveries, a scientific platform of the European Society of Cardiology (ESC). “Speech is personal and as such, very small changes (related to the same person) can be detected – for example, the ability…

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Organic lungs, synthetic muscles

Biohybrid model re-creates respiration mechanics

Benchtop tools for studying the respiratory system misrepresent the interdependence between the diaphragm, abdomen and lungs. Meanwhile, computational models often hide the mechanisms in a black box computation, without a clear picture of what transpires in the process. This means students form a poor understanding of respiratory mechanisms and makes it hard to train clinicians for real scenarios…

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Increased risk for severe infections

Up in smoke: Smoking increases SARS-CoV-2 receptors in the lung

New research suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells. The findings, reported in the journal Developmental Cell, may explain why smokers appear to be particularly vulnerable to severe infections. The analysis also indicates that the change is…

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