Sepsis

News • Current insights and research priorities

Atrial fibrillation during sepsis: what clinicians know (and what they don't)

A new review brings together the current evidence on sepsis-associated atrial fibrillation (SAAF) – and maps the research needed to close the gaps.

News • Bloodstream infections

Rethinking bacterial culturing to accelerate sepsis diagnostics

Using a specialized “broth”, researchers have developed a way to condense the days-long diagnosis timeline for sepsis to just hours, facilitating faster diagnosis and clinical decision-making.

News • Implementation assessment

Patient safety: Can “Martha's Rule” save lives?

“Martha’s Rule” is designed to give patients and families the opportunity to report concerns during hospital stay. Five years after its introduction, a study evaluates the benefits.

News • Assessing infection risk

Predicting neonatal sepsis with vaginal microbial swabs

A new study shows that analyzing bacteria from vaginal swab samples taken at delivery could help predict the risk of neonatal sepsis.

News • Disease tolerance and infection pathogenesis

Different age, same infection treatment? Not a good idea, study finds

Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.

News • New insights on nosocomial pathogen

Research reveals ‘hidden movement’ of Pseudomonas aeruginosa

Pseudomonas aeruginosa, a hospital-acquired bacterium that causes serious infections, can move from the lungs to the gut inside the same patient, raising the risk of sepsis, new research reveals.

News • Unified framework

Establishing a global standard in sepsis and critical care

The heterogeneity of critical illnesses like sepsis, ARDS, and trauma creates immense challenges. A new, unified way to classify patients aims to improve treatment.

News • Early detection of life-threatening conditions

Newborn immune profiling to improve neonatal care

Newborns, especially those born prematurely, are vulnerable to conditions such as sepsis. A new device profiles an infant’s immune function from a single drop of blood to improve neonatal care.

News • Promising project PERISCOPE

AI predicts risk of infection after operation

A new AI tool called PERISCOPE should help healthcare providers determine which patients need extra monitoring to protect them from wound or lung infections, UTIs or sepsis.

News • Pyroptosis propagation

Sepsis, or death by lethal message

Dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues report. Their findings could lead to a new understanding of this dangerous illness.

News • Clinical decision aids

Just a fever or sepsis? New way to treat babies without invasive tests

New study results could help detect whether a newborn baby with fever has sepsis or another serious bacterial infection, without the need for invasive testing.

News • Predicting bloodstream infections

AI to tackle antimicrobial resistance, sepsis, in the ICU

UK scientists are harnessing the power of AI to assess the antimicrobial resistance of patients in intensive care units (ICUs) and identify sepsis-causing bloodstream infections.

News • Overuse in spite of case reduction

Study: newborns too often receive antibiotics for sepsis prevention

The rate of sepsis in newborns across Sweden has greatly decreased – however, the use of antibiotics for sepsis prevention has not. A new study points out the extent of the overuse.

News • Bacterial blood infection diagnostics

New sepsis test gives doctors a two-day head start

A new way to analyze blood samples for suspected sepsis gives doctors test results two days earlier than before – a head start that could mean life or death for patients.

News • Only 2 out of 4 methods for EMS found to be useful

Sepsis screening: inadequate tools lead to underdiagnosis

Two out of the four screening tools used by emergency medical services are inadequate for recognising sepsis, according to new research presented at the EUSEM Congress.

News • Mapping prevalence across European hospitals

Sepsis: suprisingly common, underdiagnosed, and deadly

New research from Lund University has found a suprisingly high incidence of sepsis across hospital admissions. The experts say that the condition can be likened to an epidemic.

News • Treatment suggestions for sepsis

AI in the ICU: new model outperforms humans

An artificial intelligence developed at TU Wien (Vienna) can suggest appropriate treatment steps in cases of blood poisoning. The computer has already surpassed humans in this respect.

Article • Targeted Real-time Early Warning System for hospitals

Early detection of sepsis with the help of AI

Sepsis, a life-threatening, systemic, toxic bodily reaction to infection, is often difficult to detect in its early stages. Its symptoms, including fever, shortness of breath, rapid heart rate, and confusion, are associated with many medical conditions of hospitalized patients. But if not treated rapidly, a patient may die. The Targeted Real-time Early Warning System (TREWS) for sepsis detection…

News • Risk factor identification

AI to speed up sepsis detection

Patients are 20% less likely to die of sepsis because a new AI system developed at Johns Hopkins University catches symptoms hours earlier than traditional methods, an extensive hospital study shows.

New sepsis marker speeds up detection and therapy

Sepsis is the cause of one in five deaths worldwide, killing nearly 11 million people each year, many of them children. It is also a major cause of disability, affecting millions more. To combat the condition, many hospitals have implemented sepsis performance improvement programmes. A meta-analysis of 50 observational studies showed that these programmes are associated with better compliance…

News • Cutting risk of death

Machine learning rapidly detects sepsis

Researchers used artificial intelligence to identify sets of genes that predict whether a patient will acquire severe sepsis.

News • Blood poisoning

Sepsis: 5-country survey shows lack of public awareness

On World Sepsis Day, in vitro diagnostics company bioMérieux and the UK Sepsis Trust reveal the results of a survey conducted in Europe regarding knowledge and attitudes towards sepsis. The findings demonstrate the need to accelerate awareness and education of the general population about this life-threatening condition.

Article • Prevention

Specimen diversion devices lower blood culture contamination

Blood cultures are important laboratory tests to diagnose serious infections. Contamination is a constant concern – a patient could be misdiagnosed due to a false-positive test. Initial specimen diversion (ISD) could radically change this.

News • Sepsis detection

T2 Biosystems to participate at clinical conferences in June and July 2021

T2 Biosystems, Inc. announced the its participation in three virtual conferences this summer. The company, which specialises in the rapid detection of sepsis-causing pathogens, will take part in the American Society for Microbiology’s (ASM) and Federation of European Microbiological Societies’ (FEMS) World Microbe Forum; Sepsis Alliance’s inaugural Sepsis Tech and Innovation 2021…

News • Microneedles

No more needles for bloodtests?

Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and…

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