Sepsis

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News • Clinical decision aids

Just a fever or sepsis? New way to treat babies without invasive tests

New study results could help detect whether a newborn baby with fever has sepsis or another serious bacterial infection, without the need for invasive testing.

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News • Predicting bloodstream infections

AI to tackle antimicrobial resistance, sepsis, in the ICU

UK scientists are harnessing the power of AI to assess the antimicrobial resistance of patients in intensive care units (ICUs) and identify sepsis-causing bloodstream infections.

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News • Overuse in spite of case reduction

Study: newborns too often receive antibiotics for sepsis prevention

The rate of sepsis in newborns across Sweden has greatly decreased – however, the use of antibiotics for sepsis prevention has not. A new study points out the extent of the overuse.

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News • Bacterial blood infection diagnostics

New sepsis test gives doctors a two-day head start

A new way to analyze blood samples for suspected sepsis gives doctors test results two days earlier than before – a head start that could mean life or death for patients.

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News • Only 2 out of 4 methods for EMS found to be useful

Sepsis screening: inadequate tools lead to underdiagnosis

Two out of the four screening tools used by emergency medical services are inadequate for recognising sepsis, according to new research presented at the EUSEM Congress.

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News • Mapping prevalence across European hospitals

Sepsis: suprisingly common, underdiagnosed, and deadly

New research from Lund University has found a suprisingly high incidence of sepsis across hospital admissions. The experts say that the condition can be likened to an epidemic.

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Article • Targeted Real-time Early Warning System for hospitals

Early detection of sepsis with the help of AI

Sepsis, a life-threatening, systemic, toxic bodily reaction to infection, is often difficult to detect in its early stages. Its symptoms, including fever, shortness of breath, rapid heart rate, and confusion, are associated with many medical conditions of hospitalized patients. But if not treated rapidly, a patient may die. The Targeted Real-time Early Warning System (TREWS) for sepsis detection…

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Sponsored • Infection management

New sepsis marker speeds up detection and therapy

Sepsis is the cause of one in five deaths worldwide, killing nearly 11 million people each year, many of them children. It is also a major cause of disability, affecting millions more. To combat the condition, many hospitals have implemented sepsis performance improvement programmes. A meta-analysis of 50 observational studies showed that these programmes are associated with better compliance…

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News • Blood poisoning

Sepsis: 5-country survey shows lack of public awareness

On World Sepsis Day, in vitro diagnostics company bioMérieux and the UK Sepsis Trust reveal the results of a survey conducted in Europe regarding knowledge and attitudes towards sepsis. The findings demonstrate the need to accelerate awareness and education of the general population about this life-threatening condition.

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News • Sepsis detection

T2 Biosystems to participate at clinical conferences in June and July 2021

T2 Biosystems, Inc. announced the its participation in three virtual conferences this summer. The company, which specialises in the rapid detection of sepsis-causing pathogens, will take part in the American Society for Microbiology’s (ASM) and Federation of European Microbiological Societies’ (FEMS) World Microbe Forum; Sepsis Alliance’s inaugural Sepsis Tech and Innovation 2021…

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News • Microneedles

No more needles for bloodtests?

Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and…

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Article • Blood poisoning

Exploring the importance and challenges of early sepsis diagnosis

On the occasion of this year's World Sepsis Day, we spoke with Elena Sukhacheva, Ph.D., director of medical and scientific affairs at Beckman Coulter, about the status quo and outlook on sepsis diagnostics. With the severity of sepsis symptoms, it’s easy to comprehend why it is invaluable to diagnose this disease properly and in a timely manner. Dr Sukhacheva takes an in-depth look at…

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News • Antibacterial cellulose

A wound dressing that kills bacteria

In order to combat bacterial wound infections, Empa researchers have developed cellulose membranes equipped with antimicrobial peptides. Initial results show: The skin-friendly membranes made of plant-based materials kill bacteria very efficiently. If germs invade a wound, they can trigger a long-lasting infection that may fail to heal or even spread throughout the body, leading to…

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News • Immune system overreaction

Sepsis can cause long-term damage in the brain

Infections can trigger a particularly strong immune reaction of the body (termed sepsis). In such a sepsis the immune system reacts so strongly that not only the pathogens but also tissues and organs are damaged. In a study with mice, researchers from the Technische Universität Braunschweig were able to show that sepsis can have long-term effects on the brain and learning behaviour even after…

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News • Study offers new insights

Sepsis treatment: Destroying DNA to save the genome

Sepsis—the body's own immune response gone against it—is a major health problem worldwide. It is basically a "hyper" immune response by the body to infection or injury, and is characterized by hyperinflammation, immune system paralysis, cell death, liver and kidney failure, blood clots, and even hemorrhage. An estimated 30 million people suffer from sepsis every year, of which 20%…

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News • Decision support

AI can predict septic shock

Researchers at Linköping University (LiU) have developed an algorithm that can identify patients at a higher risk of septic shock, a life-threatening condition that is difficult for doctors to predict. At the same time, it is important to recognise the symptoms as early as possible, since early treatment increases the chance of survival. A group of LiU researchers is using artificial…

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News • 1 in 5

Sepsis death toll twice as high as assumed

Twice as many people as previously believed are dying of sepsis worldwide, according to an analysis published in The Lancet and announced at the Critical Care Reviews annual meeting in Belfast. Among them are a disproportionately high number of children in poor areas.

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News • Backup from BARDA

Sepsis early detection algorithm receives development funding

Beckman Coulter, Inc. announced that it has initially been awarded a contract of $1.25 million, with potential to be awarded an additional $6.5 million if all contract options are exercised, from the DRIVe (Division of Research, Innovation, and Ventures) established by the Biomedical Advanced Research and Development Authority (BARDA), under the Office of the Assistant Secretary for Preparedness…

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News • Respiratory failure and sepsis

Cheap, quick test identifies major risks for pneumonia patients

Spanish researchers in Valencia have identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. Presenting the research at the European Respiratory Society International Congress, Dr Francisco Sanz said the findings could enable doctors to test quickly for these biological markers when a patient is admitted to…

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Sponsored • Hematology

Early sepsis indicator helps identifying patients at risk

The critical element of testing for sepsis lies not so much in the location but in the timing and rapidity of results, according to Professor Jeannine T. Holden from Beckman Coulter Early identification enables treatment protocols to be delivered more quickly, offering better patient outcomes. Those most at risk, suggests Holden, are not patients within the intensive care unit – who are already…

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