Keyword: diabetes

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Heat therapy

Soaking in a hot tub has unexpected benefits, researchers find

According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…

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Epidemiological study

Vitamin D deficiency linked to increased diabetes risk

An epidemiological study conducted by researchers at University of California San Diego School of Medicine and Seoul National University suggests that persons deficient in vitamin D may be at much greater risk of developing diabetes. The scientists studied a cohort of 903 healthy adults (mean age: 74) with no indications of either pre-diabetes or diabetes during clinic visits from 1997 to 1999,…

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Smoking cessation

Common diabetes drug may also help with nicotine withdrawal

In a mouse study, a drug that has helped millions of people around the world manage their diabetes might also help people ready to kick their nicotine habits. In a report published in The Proceedings of the National Academy of Sciences of the United States of America (PNAS), investigators say metformin, an inexpensive drug commonly used to treat patients with type 2 diabetes, appears to block…

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Paradigm shift

Diabetes has 5 subtypes, not 2, study suggests

A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actually consists…

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Don't turn a blind eye

Annual dilated eye exams key in preventing diabetic eye disease

Diabetic eye disease is the leading cause of blindness among people ages 40 to 60. The longer you have diabetes, the greater your likelihood of developing vision problems increases. Keeping blood sugar, blood pressure and cholesterol levels under control can help people with diabetes maintain good eye health. They must also have a dilated eye exam once a year, says Dr. Malav Joshi, an…

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Is the "American Dream" slipping away?

Drugs, alcohol and suicides contributing to alarming drop in US life expectancy

Drugs, alcohol and suicides are contributing to an alarming drop in US life expectancy, particularly among middle-aged white Americans and those living in rural communities, warn experts in The BMJ. Steven Woolf at Virginia Commonwealth University and Laudan Aron at the Urban Institute in Washington DC, argue that the ideal of the “American Dream” is increasingly out of reach as social…

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Broken immune clock

Why shift work might be to blame for obesity and diabetes

About 15 million Americans don’t have a typical nine-to-five workday, and many of these—nurses, firefighters and flight attendants, among many other professions—may see their schedule change drastically one week to the next. As a result, these shift workers’ biological clocks, which keep track of the time of day, cannot keep accurate time, potentially making the negative effects of a high…

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Old technique & new technology

Optoacoustics: the sound of cells

For centuries, hands, eyes and ears were the physicians’ most important instruments when it came to detecting and diagnosing disease. Today, one of the traditional techniques, percussion, is being revived, supported by state-of-the-art technology and dressed in a new name: optoacoustics. In one of the most exciting visionary ideas in modern healthcare short laser pulses (optics) are transmitted…

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Regulatory B cells

Researchers identify new marker for autoimmune disorders

The immune system is a complex and precisely regulated system. Various activating and inhibiting signals ensure that the immune cells combat pathogenic agents without eliciting a potentially harmful response to its own structures and cells. However, if those two forces are imbalanced, the immune cells may attack and damage cells and tissue of the body itself, which will result in the development…

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Efferocytosis

Can stem cell exosome therapy reduce fatal heart disease in diabetes?

Macrophage cells routinely remove dead or dying cells to maintain the body homeostasis. Such removal becomes crucial after serious injury, especially the repair of dead heart muscle after a heart attack. University of Alabama at Birmingham researchers have preliminary data, with cultured cells or diabetic hearts, that diabetes impairs this removal of dead heart-muscle cells. They believe this…

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Not so sweet after all

Could sugar be responsible for the obesity and diabetes epidemics?

The idea that sugar could be a fundamental cause of the global obesity and diabetes epidemics, with deleterious effects on the human body that go beyond just empty calories, should be considered seriously again, argues journalist and author Gary Taubes in The BMJ. In the midst of such a huge public health crisis, Taubes says “we must do more to discourage consumption while we improve our…

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Ophthalmology

Researchers explore way to reverse diabetic blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments that suppressed vascular endothelial growth factor (VEGF) in the eye, researchers were able to re-establish normal blood…

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Sugar and health

The not so sweet side of Christmas

A new video by the University of Warwick highlights a bitter side to our sugar consumption at Christmas. The short film highlights how excessive consumption of sugar can affect our health – and how the sugar trade in the past and today has caused inequality and bloodshed. Today Britons eat too much sugar, on average 10 per cent of our daily calories come from sugar which is equivalent to 60 g…

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Better together

Making diabetes and hypertension management a community activity

Managing diabetes and high blood pressure can feel like a solitary enterprise dependent on relationships with objects (like pills or foods) and activities (like brisk walks or early bedtimes) instead of relationships with people, but a group of West Virginia University researchers is hoping to change that. The National Institutes of Health has awarded $450,000 to Ranjita Misra, a professor of…

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Diabetes research

Novel transcriptomic signature of type 2 diabetic islets identified

Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels within the range for a healthy life. A collaborative study led by Prof. Michele Solimena at the Technische Universität in Dresden as well as the Helmholtz Zentrum München, Dr. Anke M Schulte at…

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The AßC of diabetes

Smart artificial beta cells could lead to new diabetes treatment

Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the University of North Carolina and NC State have now developed what could be a much more patient-friendly option: artificial cells that automatically release insulin into the bloodstream when glucose levels…

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Phosphatidic acid phosphatase

A fat-regulating enzyme could hold the key to obesity and diseases

It had already been known that the enzyme known as phosphatidic acid phosphatase plays a crucial role in regulating the amount of fat in the human body. Controlling it is therefore of interest in the fight against obesity. But scientists at Rutgers University-New Brunswick have now found that getting rid of the enzyme entirely can increase the risk of cancer, inflammation and other ills.

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Glucose control

"Sugar sponges" - diabetes treatment of the future?

Many diabetes patients must inject themselves with insulin, sometimes several times a day, while others take medications orally to control blood sugar. The injections, as well as the side effects from both regimens, can be painful. Now, one team reports in the Journal of the American Chemical Society progress toward an insulin-free diabetes treatment that requires fewer injections.

Diabetes research

Healing burn wounds with cell therapy

An experimental treatment in mice allows the reprogramming of blood cells in order to promote the healing process of cutaneous wounds. This approach could prove to be beneficial in healing challenging wounds in diabetics and major-burn victims.

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Artificial beta cells

New weapon against Diabetes

ETH Researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.

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Additive manufacturing

3D printing: customized insoles for diabetes patients

In the past, insoles for patients with diabetes were hand-made by orthopedic shoemakers. In the future, these specialist shoemakers will be able to produce insoles more cost-effectively thanks to new software and the use of 3D printers. This approach means the mechanical properties of each insole can be assessed scientifically and more effectively.

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Diabetes

Friendly Fire in the Pancreas

n type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal ‘PNAS’ about a mechanism used by the immune system to prepare for this attack. They were able to inhibit this process through targeted…

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