Research

When scientific curiosity paves the way for improved healthcare: Read more about promising studies and trials that lead to more effective drugs, procedures as well as medical guidelines.

News • In vitro disease models

'Intrepid' research to advance cancer therapies

A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.

News • 3D printed blood vessels

'Artery on a chip' could unravel secrets of strokes

Researchers have developed a new 3D printing technique for blood vessels on glass. This could be a tool for studying stroke causes and testing patient-specific medications without animal testing.

News • 3D-printable polymer

Print, stretch, implant: new material could help build artificial organs

Researchers have developed a novel 3D-printable material that is both biocompatible and highly elastic. The technology could pave the way for artificial organs and improved drug delivery systems.

Article • San Antonio Breast Cancer Symposium (SABCS)

Young women and breast cancer: research in focus

At the San Antonio Breast Cancer Symposium (SABCS), three experts presented new approaches and study results for the treatment of breast cancer in young women.

News • Attenuation contrast und dark field

One X-ray, three images: new method unveils hidden features

Researchers developed an X-ray imaging method capable of revealing hidden features in a single shot. This could advance cancer detection, disease monitoring, security screening and material analysis.

News • Co-morbidity research

Sleep disorder combo greatly raises hypertension risk

Having multiple sleep disorders, such as OSA and insomnia, has been identified as a strong risk factor for uncontrolled hypertension. This could help identify patients in need of closer monitoring.

News • Sex-specific dysregulation

Why women are three times more likely to get severe long Covid

New research reveals why women with long Covid — especially those who develop chronic fatigue syndrome — tend to experience more severe and persistent symptoms than men do.

News • New targetable driver of growth found

Thyroid gland: unexpected key to prostate cancer treatment

An international research team has discovered a promising new therapeutic approach for aggressive prostate cancer – in the thyroid gland.

News • Targeted drug activation

Ultrasound-triggered chemotherapy to reduce side-effects

Researchers explore how ultrasound waves can be used to activate chemotherapy drugs only in targeted areas, offering a new path toward safer, more effective cancer treatment.

News • Link between Covid, flu, HIV and CVD

Viral infections may increase the risk of cardiovascular disease

After a bout of influenza or Covid, the risk of heart attack or stroke may rise dramatically, and chronic infections may increase the long-term risk of serious cardiovascular disease events.

News • Health consequences of climate change

Heatwaves raise sleep apnoea risk in Europe

A major European study shows heatwaves increase the risk for obstructive sleep apnoea (OSA). This finding has serious implications as climate change intensifies, the researchers say.

News • Selective degradation of neurons

ALS: Key mechanism behind motor function loss discovered

Why does amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, attack motor neurons, the cells that control body movement, while others are spared? A new study may have found an answer.

News • Neurostimulation system

New implant partially restores vision in AMD patients

A novel subretinal implant could help patients with age-related macular degeneration (AMD) partially restore eyesight, a new study shows. Participants recovered their ability to read letters, numbers and words.

News • Transition changes

How menopause restructures a woman’s brain

During menopause, many women experience forgetfulness, trouble concentrating, and mental fatigue. A new review explores the link between brain changes during menopause and these symptoms.

News • Transformer-based learning from radiomics and clinical data

New AI model improves prediction of breast cancer recurrence

An international team has developed an AI model that brings together medical imaging data and clinical information to calculate the risk of breast cancer tumour recurrence more accurately.

News • Hypertensive disorders of pregnancy

Preterm babies put mothers' heart health at risk

The bigger the baby, the bigger the risk: A new study shows that the birthweight of a preterm infant is linked to its mother's risk of getting cardiovascular disease later in life.

News • Non-invasive structured bioink deposition

A pill-sized bioprinter could repair GI tract injuries from the inside

To help repair soft tissue injuries of the gastrointestinal tract like ulcers or hemorrhages, EPFL researchers envision a new class of device: a pill-sized, swallowable bioprinter.

News • Long-term subcutaneous EEG

Breaking new ground to advance seizure monitoring and epilepsy diagnosis

Traditional diagnostic methods for epilepsy face significant limitations. A new clinical trial explores the potential of advanced brain monitoring to improve diagnosis and management of the condition.

News • Radiation-induced cognitive decline

New approach to protect the brain during radiation therapy

Researchers identified a targeted way to protect the brain from harmful side effects of cranial radiation therapy, potentially preserving the quality of life for millions of brain cancer survivors.

News • Reproductive and hormonal factors

Early menopause associated with higher dementia risk

Entering menopause at an earlier age is associated with an increased risk of dementia, a new study finds. The research also suggests a way for women to combat the cognitive decline.

News • Virtual, dynamic model

"Immune Digital Twins" to tackle autoimmune disorders, infectious diseases

An international project to create a ‘digital twin’ of the human immune system could help scientists finally tackle grand challenges such as autoimmune disorders and infectious diseases.

News • Melancholic vs. fatigued

Depression subtypes linked to different cardiometabolic diseases

It is known that depression is linked to increased incidence of metabolic diseases; now scientists have discovered that different types of depression are linked to different cardiometabolic diseases.

News • New biomaterials

Building durable, infection-resistant implants with liquid metal

Integrating liquid metal nanomaterials into a ceramic scaffold could improve the durability and biocompatibility of orthopedic implants, while also combatting antimicrobial resistance.

News • Study explores clinical potential of WGS

Whole genome sequencing could help 15,000 breast cancer patients per year, study finds

Breast cancer claims around 670.000 lives each year. Now, researchers propose that whole genome sequencing (WGS) could help many patients find better treatments or match them with clinical trials.

News • Depth-resolved fiber photometry

Tracking Alzheimer’s progression in real time

Scientists have developed a new method to track the build-up of amyloid plaques – a key characteristic of Alzheimer’s disease – in real time – an important step forward towards new treatments.

News • Precision Oncology Ireland (POI)

Ireland’s largest ever cancer research programme enters next phase

Precision Oncology Ireland (POI), a €28M cancer research programme uniting universities, charities and industry to develop tailored diagnostic and therapeutic solutions, has now entered phase 2.

News • Quantitative analysis of the mammary ductal tree

Calculating breast health with branching math

Researchers have developed a tool to quickly quantify changes in the branches of mouse mammary glands. This could one day be used to detect early warning signs of breast cancer.

News • Postural Orthostatic Tachycardia Syndrome

Heart rhythm disorder POTS common in long Covid patients

Dizziness upon standing up or during exertion: Postural orthostatic tachycardia syndrome (POTS) affects almost a third of patients with severe long Covid, a new study finds.

News • Peripheral immune tolerance

Immune system researchers receive Nobel Prize 2025 in Medicine

The 2025 Nobel Prize in Physiology or Medicine is awarded to three researchers for their insights into peripheral immune tolerance - how our immune system is kept from attacking our own body.

News • AML targetable immune escape mechanism

How leukemia cells trick the immune system

Immunotherapy has improved the treatment for many cancers, but progress has been limited in leukemia. Discovery of a new evasive mechanism could help change that.

News • Study shows widespread disruption

Glioblastoma: damage beyond the brain

Scientists have shown for the first time that glioblastoma—the deadliest form of brain cancer—affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body’s immune response.

News • How much does it hurt?

‘Monetizing’ pain for more accurate assessments

Asking people how much money they would accept to experience pain again can provide a more accurate and comparable measure of pain levels than the familiar 1–10 scale, according to new research.

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