Biomarkers

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News • Body composition radiodensity

New CT-based marker to refine gastric cancer prognosis

Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.

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News • Diaphragmatic dome height

Simple X-ray measure linked to survival in lung cancer surgery patients

A new study shows that diaphragmatic dome height (DDH) - a simple measurement from routine chest X-rays - can help predict survival among patients with lung cancer and breathing disorders.

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News • Microscopy

New microscopy method maps lipids without labels

A new microscopy method reads lipids' natural spectral fingerprints using mid-infrared light and ultrasound – no fluorescent labels needed, less stress for living cells.

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News • Alternative to conventional tests

Affordable biosensor to early detect pancreatic cancer

Researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device offers a simpler, more affordable alternative to conventional tests, which are…

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News • Ventricle morphology

Hydrocephalus: 3D brain marker helps predict shunt surgery success

A 3D brain marker may help identify which patients with idiopathic normal pressure hydrocephalus (iNPH) benefit from shunt surgery – improving outcomes and sparing others from ineffective treatment.

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News • Mammary tumorigenesis

New marker identifies which breast lesions will progress to cancer

Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.

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Article • Digital pathology and AI

Finding new biomarkers to match the biological complexity of cancer

Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…

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Article • Reshaping GI cancer care

Pathologists at the heart of precision oncology

Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…

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