Biomarkers

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News • Potential diagnostic medium

Saliva analysis could reveal risk of cancer, heart disease or Parkinson’s

Molecular markers in saliva could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases, new research finds.

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News • Dual role of tau phosphorylation

Surprising find: Alzheimer's biomarker found in newborn brains

What do the brains of newborns and patients with Alzheimer's disease have in common? Researchers have discovered a surprising shared trait - which might provide new insights into the disease.

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News • Genetic signature mapping

Diagnosing Parkinson’s from a blood sample

In a world first, researchers have identified a set of biomarkers that could someday make it easy to spot Parkinson's disease in a patient’s blood sample.

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News • Retinal functional impairments as biomarkers

Eye exam shows potential for early detection of Parkinson's disease

Researchers from Université Laval discovered that the retina of people with Parkinson's disease responds differently to light than that of healthy people. This offers new diagnostic options.

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News • Promising biomarker found

Broad rim lesions predict multiple sclerosis progression

A new biomarker for multiple sclerosis: the inflammatory cell rim from microglial cells surrounding brain lesions was found to directly correlate with the severity and speed of disease progression.

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News • Reactions to noise as biomarkers

Tinnitus diagnosis via AI-powered face scan

Pupil dilation and involuntary facial movements could provide a window into diagnosing tinnitus. A new method uses AI to detect minuscule reactions to various sounds and noises.

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Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…

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Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

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Article • Molecular meets digital

Single-cell multiplex imaging: a powerful tool for digital pathology

Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…

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