Printing

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Healing support

Bioprinting for bone repair improved with genes

An international team of engineers is bioprinting bone along with two growth factor encoding genes that help incorporate the cells and heal defects in the skulls of rats.

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'Sweet' assistance

3D printed vascular models to help cancer therapy

3D-printed sugar models of dense and chaotic blood vessel networks near tumors could help future cancer treatments.

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Additive manufacturing

3D printing testicular cells

In a pair of world firsts, scientists have 3D printed human testicular cells and identified promising early signs of sperm-producing capabilities.

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Additive manufacturing

'Smart' 3D-printed braces for scoliosis treatment

Researchers have developed a new type of lightweight 3D-printed back brace capable of sensing how effectively it fits patients. Its developers say it could lead to improved treatment for scoliosis.

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Additive manufacturing

3D printable biomaterial for personalised medicine

Evonik offers a comprehensive portfolio of 3D printable med-tech biomaterials that can be used to produce medical devices with temporary or permanent body contact. Marc Knebel, head of Medical…

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Bioprinting

3D biocomposites can repair large bone defects

Loosening hip implants can cause major damage to the bone and a simple replacement won’t suffice to carry the load during movements. “To solve this problem we have to turn to innovative…

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Microbiology

Using 3D printing technique to create biofilms

Researchers at the University of Rochester, and Delft University of Technology in the Netherlands recently developed a 3D printing technique to engineer and study biofilms—three-dimensional communities of microorganisms, such as bacteria, that adhere to surfaces. The research provides important information for creating synthetic materials and in developing drugs to fight the negative effects of…

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Titanium-alloy knee plates

3D printing simplifies high tibial osteotomy

3D metal printing technology is producing personalised medical-grade titanium-alloy plates that perfectly fit individuals suffering arthritis of the knee. Engineers at the University of Bath’s Centre for Therapeutic Innovation (CTI) working with 3D Metal Printing Ltd, are using the TOKA (Tailored Osteotomy for Knee Alignment) treatment to improve the surgical procedure and fit of high-tibial…

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Brain cancer research

Researchers 3D-print entire active tumor

Researchers at Tel Aviv University have 3D-printed a first-of-its-kind glioblastoma tumor that mimics a living cancer malignancy, powering new methods to improve treatment and accelerate the development of new drugs for the most lethal type of brain cancer. Glioblastoma is notoriously fatal as it accounts for the majority of brain tumors and is highly aggressive. The average survival time of…

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Microscopy

New imaging technique to improve 3D printed bio-implants

University of Birmingham scientists have developed a new microscopic imaging approach to take a closer look at 3D-printing for developing future patient implants, as well as improved disease modelling and drug screening. Additive manufacturing (3D printing) platforms create bioprinted structures by moving a special bioink, containing cells, biomolecules and materials, through a narrow tube, but…

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Bioprinting breakthrough

3D printed mini pancreas to help fight diabetes

First you see it as a transparent shape on a computer screen – a small electronic replica of the human pancreas. Then just 30 seconds later the tissue is printed out on a bioprinter, blood vessels and all, from a sample of human stem cells. This amazing feat is possible thanks to new technology created at EPFL’s Laboratory of Applied Photonics Devices (LAPD) and further developed by…

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Freefrom Reversible Embedding of Suspended Hydrogels

A 'FRESH' way to 3D-print tissues and organs

Research into 3D bioprinting has grown rapidly in recent years as scientists seek to re-create the structure and function of complex biological systems from human tissues to entire organs. The most popular 3D printing approach uses a solution of biological material or bioink that is loaded into a syringe pump extruder and deposited in a layer-by-layer fashion to build the 3D object. Gravity,…

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Creating instruments, implants & more onsite

Reforming surgical procedures with 3D printing hubs in hospitals

Increasingly, hospitals use 3D printing in surgery because the technology can enable fast, unique production of patient-tailored tools at relatively low costs. ‘As the technology itself is developing and accelerating at a fast pace, hospitals may be left behind if they choose not to adopt these advances,’ said Limor Haviv, surgical 3D printing designer at 3D4OP. Today, 3D printing is used in…

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Gels for drug delivery systems

'Soft' 3D printing could jump-start creation of tiny medical devices

Researchers at the U.S. National Institute of Standards and Technology (NIST) have developed a new method of 3D-printing gels and other soft materials. Published in a new paper, it has the potential to create complex structures with nanometer-scale precision. Because many gels are compatible with living cells, the new method could jump-start the production of soft tiny medical devices such as…

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Rapidly meeting a surging demand

The science behind 3-D printed nasal swabs

Medical device approved 3-D printers are producing clinically safe and effective nasopharyngeal swabs for COVID-19 testing. A nasal swab may seem rudimentary, but is essential for testing COVID-19. Diagnostic test kits and components – nasal swabs, collection vials, and chemical reagents – have been in short supply worldwide, especially in March. Ironically, nasopharyngeal swabs are…

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3D microprinted scope

World’s smallest imaging device focuses on heart disease

A team of researchers led by the University of Adelaide and University of Stuttgart has used 3D micro-printing to develop the world’s smallest, flexible scope for looking inside blood vessels. The camera-like imaging device can be inserted into blood vessels to provide high quality 3D images to help scientists better understand the causes of heart attack and heart disease progression, and could…

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Acetone sensors

3D printing sensors for diabetes breath tests

The production of highly sensitive sensors is a complex process: it requires many different steps and the almost dust-free environment of special cleanrooms. A research team from Materials Science at Kiel University (CAU) and from Biomedical Engineering at the Technical University of Moldova has now developed a procedure to produce extremely sensitive and energy-efficient sensors using 3D…

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Diabetes-related diseases

3D printed implants for personalized treatment of bone defects

BellaSeno GmbH, a company developing absorbable scaffolds using additive manufacturing technologies, announced a collaboration with Charité – Universitätsmedizin Berlin under the recently established SyMBoD consortium. Under the agreement, BellaSeno will design and manufacture personalized, 3D-printed, absorbable implants suitable for the treatment of diabetes patients with bone defects. The…

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Glioblastoma

New imaging technique to study 3D printed brain tumors

Glioblastomas are complex, fast-growing malignant brain tumors that are made up of various types of cells. Even with aggressive treatment — which often includes surgery, radiation, and chemotherapy — glioblastomas are difficult to treat, leading to an average survival of 11-15 months. In research published in Science Advances, Xavier Intes, a professor of biomedical engineering at Rensselaer,…

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Hope for new skin grafts

3D printed living skin complete with blood vessels

Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally. “Right now, whatever is available as a clinical product is more like a fancy Band-Aid,” said Pankaj Karande, an…

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Tissue construct

A 'swift' way to 3D-print organs

Twenty people die every day waiting for an organ transplant in the U.S., and while more than 30,000 patients now receive transplants annually, another 113,000 are currently on organ waitlists. Many people see artificially grown human organs as the Holy Grail for resolving the organ shortage, and advances in 3D printing have led to a boom in using that technique to build living tissue constructs…

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Let it grow

3D printed templates for bone implants made of salt

With the help of a 3D printed salt template, ETH researchers from ETH Zurich have succeeded in producing magnesium scaffolds with structured porosity that are suitable for bioresorbable bone implants. For the treatment of complex bone fractures or even missing bone parts, surgeons typically deploy metal implants. In this context, an attractive alternative to the traditional materials like…

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