The pancreas produces important hormones – especially insulin, which regulates blood sugar, and ghrelin, which stimulates appetite. If the function of the pancreas is disturbed, diabetes can be the result, but gastrointestinal diseases such as pancreatitis are also highly relevant in medicine – as is pancreatic cancer, which is one of the most aggressive and deadly tumour types.
Pancreatic cancer is one of the most aggressive cancers, partly due to its tumor microenvironment, known as the stroma. Now, a study has identified a new key factor contributing to this feature.
Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.
Leveraging bioink from pancreatic tissue and 3D bioprinting, researchers developed a structure closely mimicking the structure of a pancreas, in which cultured cells can resume insulin production.
Pancreatic cystic lesions – indicating an increased risk of pancreatic cancer – are an occasional incidental finding in routine computed tomography (CT) abdominal imaging. New research suggests that the superior image quality of photon-counting CT (PCCT) can help detect more of these lesions. At the RSNA annual meeting, an expert outlined the benefits and limitations of the imaging technique…
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
In a new study, researchers have shown, for the first time, that a particular form of MRI, called diffusion tensor imaging, is capable of robustly detecting pre-malignant lesions in the pancreas.
A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.
New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.
Insulinomas are benign tumors in the pancreas, but can still cause problems for patients. A new imaging technique reliably detects these previously hard-to-find tumors, according to recent research.
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
In more than one in six patients diagnosed with pancreatic cancer, the tumour is initially diagnosed at a non-metastatic primarily unresectable, locally advanced stage (LAPC). For these patients, a new internal radiation procedure, OncoSil™ brachytherapy, may become a treatment option – in Germany, around 858 patients could benefit from this innovation annually.
US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.
Pancreatic cancer is not just one disease, but that’s the way it is currently treated. New work from Columbia University could help pave the way for a change.
For pancreatic cancer, the effect of immunotherapy is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this sex difference.
A new study from Spain has demonstrated the efficiency of an ultrasound radiation-based therapy on the inhibition of cancer cell motion in pancreas cancer models.
Treating pancreatic cancer patients with chemotherapy before surgery significantly improved 1-year survival rates compared to immediate surgery, a randomised clinical trial has found.
