Virus

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Rapid detection

Molecular diagnostic test for Covid-19, Flu, RSV receives CE mark

A new rapid molecular diagnostic test from Cepheid has received the CE mark for distribution in the European market. The test, called Xpert Xpress CoV-2/Flu/RSV plus, is designed for qualitative…

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Cerebrovascular injuries

Infection hinders blood vessel repair following traumatic brain injury

Researchers have found a possible explanation for why some patients recover much more poorly from brain injury if they later become infected.

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Better ventilation needed

COVID-19 virus gets better at becoming airborne

Study suggests need for better ventilation and tight-fitting masks, in addition to widespread vaccination to help stop spread of the virus.

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Combined with antibiotics

Bacteria-killing viruses to fight antibiotic-resistant bacteria

Researchers have found a way to defeat the multi-resistant bacterium Mycobacterium abscessus, a relative of the causes of tuberculosis and leprosy.

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Battle against Covid-19 & other infectious diseases

WHO opens Hub for Pandemic and Epidemic Intelligence in Berlin

To better prepare and protect the world from global disease threats, H.E. German Federal Chancellor Dr Angela Merkel and Dr Tedros Adhanom Ghebreyesus, World Health Organization (WHO)…

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Research on after-effects

Viruses leave traces long after the infection is over

Viruses do not always kill the cells they infect. Researchers at the University of Basel have discovered in experiments with mice that cells have the power to self-heal and eliminate viruses.…

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Mechanical inactivation

'Nano traps' to lock up and neutralize viruses

To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell…

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AI-assisted analysis

Prediciting viral infections with microscopy & deep learning

When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy. Using fluoresence images from live cells, researchers at the University of Zurich have trained an artificial neural network to reliably recognize cells that are infected by adenoviruses or herpes viruses. The procedure also identifies severe acute infections at an early stage.

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Corona and EBV

Long Covid symptoms likely caused by Epstein-Barr virus reactivation

Epstein-Barr virus (EBV) reactivation resulting from the inflammatory response to coronavirus infection may be the cause of previously unexplained long Covid symptoms—such as fatigue, brain fog, and rashes—that occur in approximately 30% of patients after recovery from initial Covid-19 infection. The first evidence linking EBV reactivation to long Covid, as well as an analysis of long Covid…

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Good news

Mild COVID-19 induces lasting antibody protection

Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.

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Molecular research

How retroviruses become infectious

Understanding every step in the life cycle of a virus is crucial for identifying potential targets for treatment. Now, scientists at the Institute of Science and Technology (IST) Austria were able to show how a virus from the retrovirus family – the same family as HIV – protects its genetic information and becomes infectious. Furthermore, they show an unexpected flexibility of the virus. This…

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Helminths

Worm infestation in the gut can lower viral defenses

Infection with parasitic intestinal worms (helminths) can apparently cause sexually transmitted viral in-fections to be much more severe elsewhere in the body. This is shown by a study led by the Universities of Cape Town and Bonn. According to the study, helminth-infected mice developed significantly more severe symptoms after infection with a genital herpes viruses (Herpes Simplex Virus). The…

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Protection from bacteria, fungi, viruses

Antimicrobial technologies – how do they work?

Antimicrobial technologies such as coatings and textiles containing silver and copper are helping people during the Covid-19 pandemic by ensuring that whatever they touch, whether that is a door handle or their own mask, is free from live SARS-CoV-2 particles. But how exactly do these antimicrobial technologies work? How can a silver, copper or even polymeric coating kill microorganisms such as…

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HPV testing advances

Cervical cancer screening: Emerging tech to replace Pap smears

Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives both in developing nations and parts of countries, like the United States, where access to health care may be limited. In Biophysics Reviews, by AIP Publishing, scientists at Massachusetts General Hospital write advances in nanotechnology and computer learning are among the…

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Nanotechnology

New low-cost solution for virus-scale microscopy

Using an ordinary light microscope, engineers at the Massachusetts Institute of Technology (MIT) have devised a technique for imaging biological samples with accuracy at the scale of 10 nanometers — which should enable them to image viruses and potentially even single biomolecules, the researchers say. The new technique builds on expansion microscopy, an approach that involves embedding…

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Mutations of SARS-CoV-2 & Co.

Tracking virus variants faster with sequencing

A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future. In a comment piece in the journal Nature, an international collaboration of specialists in viral and genetic analysis, led by Swiss scientists Dr. Emma Hodcroft at the University of Bern and…

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Cancer vaccine research

Tackling tumors with two types of virus

An international research group led by the University of Basel has developed a promising strategy for therapeutic cancer vaccines. Using two different viruses as vehicles, they administered specific tumor components in experiments on mice with cancer in order to stimulate their immune system to attack the tumor. The approach is now being tested in clinical studies.

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Lessons learned from Covid-19

A 'blueprint' for preventing the next pandemic

Scientific and public health experts have been raising the alarm for decades, imploring public officials to prepare for the inevitability of a viral pandemic. Infectious epidemics seemingly as benign as "the flu" and as deadly as the Ebola virus provided ample warning, yet government officials seemed caught off guard and ill prepared for dealing with Covid-19.

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Herd immunity explained in virtual reality

Using VR to win over vaccine skeptics

People who are sceptical of getting vaccinated against infectious diseases may soon get a whole new perspective on things. Professor Robert Böhm and Associate Professor Guido Makransky from the Center for Social Data Science (SODAS) and the Department of Psychology at the University of Copenhagen have received DKK three million in funding from EIT Health for developing a virtual reality app to…

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A closer look at thapsigargin

Potential antiviral treatment for Covid-19 found

Researchers from the University of Nottingham have discovered a novel antiviral property of a drug that could have major implications in how future epidemics/pandemics – including Covid-19 – are managed. The study, published in Viruses, shows that thapsigargin is a promising broad‑spectrum antiviral, highly effective against SARS-CoV-2, a common cold coronavirus, respiratory syncytial virus…

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Viral sequencing

How SARS-CoV-2 spreads and evolves

The emergence of SARS-CoV-2 virus variants that are adding twists in the battle against COVID-19 highlight the need for better genomic monitoring of the virus, says Katia Koelle, associate professor of biology at Emory University.

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Virion recreated

First computational model of entire SARS-CoV-2 virus

Researchers at the University of Chicago have created the first usable computational model of the entire virus responsible for Covid-19—and they are making this model widely available to help advance research during the pandemic. “If you can understand how a virus works, that’s the first step towards stopping it,” said Prof. Gregory Voth, whose team created the model published in…

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Dangerous immune response

New insight on severe virus attacks on the lungs

In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for Covid-19, among other diseases.

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