Pathology

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News • Assessment of tumour-infiltrating lymphocytes

Skin cancer: AI assistance helps pathologists identify melanoma

More consistent TIL assessments, more accurate patients' prognoses: New research shows how AI sharpens pathologists' interpretation of tissue samples for malignant melanoma.

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News • MRD assessment

Liquid biopsy to detect breast cancer relapse up to 5 years in advance

Newly developed technology can detect breast cancer relapses up to five years in advance. This advance could represent a turning point in post-treatment follow-up, the researchers hope.

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News • Amyotrophic lateral sclerosis

New insights on ALS onset opens paths to earlier treatment

New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.

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News • Faster, more accurate treatment

Basal cell carcinoma: AI support for Mohs surgery

Dutch researchers have developed an AI tool to support Mohs surgery, a precise but time-consuming procedure to treat the most common form of cancer in the Netherlands: basal cell carcinoma.

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News • Mechanopathology

'Dengue-on-a-chip' to study infection mechanisms

Due to the effects of climate change, dengue is spreading worldwide. Now, researchers have developed a 'dengue-on-a-chip' model that helps study the virus more effectively.

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News • Double Stokes polarimetric microscopy

New method to help accelerate cancer diagnosis

A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.

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Article • Digital pathology discussion panel

The AI tools pathologists want and need

The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at current and future technology options. The panel of pathologists, scientists and academics from Europe and the USA assessed the tools they currently use and are available to them, and those they…

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Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…

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Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

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Article • Keynote on integrated diagnostics

Predicting – and shaping – the future of modern pathology

Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in Florence, Italy, Professor Manuel Salto-Tellez highlighted this as one of the major future challenges for the discipline. However, he also believes pathologists will sit at the core of modern medicine.

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Sponsored • Collaboration in pathology

MEDIPATH makes a step towards lab automation with the help of Sakura Finetek Europe

Sakura Finetek Europe and MEDIPATH, a group of independent French pathologists, announced their collaboration to enhance cancer diagnostics and thus contribute to improved patient therapeutic management. This decision is part of an ongoing commitment to improving the quality of care provided to patients and in response to the significant increase in cancer cases over the last years.

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Article • Transformative technology

Debating the case for AI in pathology

Artificial Intelligence (AI) remains a divisive topic within the discipline of pathology with a range of opinions over its current value and applicability in clinical settings. While most experts agree that the technology will not replace pathologists, it might still spell bad news for those who do not embrace AI in their daily practice. On the other hand, reservations persist about whether…

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Article • Molecular meets digital

Single-cell multiplex imaging: a powerful tool for digital pathology

Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…

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