Pathology

News • Tailored chatbot

Customized ChatGPT to advance digital pathology

New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.

News • Tumour infiltrating lymphocyte measurement

Breast cancer: AI tool predicts which DCIS cases become invasive

Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.

Article • Challenges and opportunities

Molecular pathology in Europe: in search of standardization

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it…

News • Infectious disease diagnostics

POCT for remote areas: Portable pathology passes the test

When point-of-care testing (POCT) models for diagnosing infectious disease are effective, the quality of pathology results can be equivalent to laboratory tests, new research shows.

Leaping forward with laboratory workflow automation

Embark on a journey of unparalleled efficiency and precision with Sakura Finetek Europe's newest innovation in identification technology: the Tissue-Tek xPrint® LP Laser Cassette Printer.

News • Neuropathology

Technology offers new insights into pediatric brain tumors

A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

Article • Pros and cons of diagnostic techniques

Liquid biopsy vs. tissue biopsy: Getting the best of both worlds

Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.

News • Three-dimensional tissue processing

Pathology performs leap into 3D with AI

Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.

News • Research on large foundation models

Reducing bias in pathology AI

A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.

News • Pathology solutions provider

Jaap Stuut appointed as Sakura Finetek President

Sakura Finetek Europe has appointed Jaap Stuut as the President and General Manager. He will lead the company's EMEAI division in this role, shaping the its mission, vision, and long-term strategy.

News • New-found blood signatures

Multiple sclerosis: subtype discovery opens new ways for personalized therapy

Researchers discovered three distinct immunological endophenotypes of multiple sclerosis, defined by specific blood immune signatures. This opens new avenues for personalized treatment strategies.

Article • Interdisciplinary diagnostics

Crossing the radiology-pathology boundary

In diagnostics, there used to be a hard divide between radiology and pathology, where methods were largely considered incompatible with one another. However, to pave the way for next-generation diagnosis, Professor Regina Beets-Tan urged both sides to come out from their trenches and appreciate the synergies the fields have to offer. In her presentation at the European Congress of Radiology (ECR)…

Article • Improving quality and efficiency

Preparing for AI in clinical laboratories

Some year in this decade, AI tools will become ubiquitous within clinical laboratories. AI has the potential to increase the accuracy of laboratory testing and improve the quality and efficiency of operations and service of testing labs.

News • Interpretable machine learning system

AI to detect colorectal cancer from pathology slides

Researchers work on the first prototype that applies AI to colorectal diagnosis. The prototype achieved a diagnostic acuity of 93.44% and a sensitivity of 99.7% in the detection of high-risk lesions.

News • Histological transformation

How lung cancer can transform into another type

Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.

News • Mitosis profiling

AI tool helps grade cancer based on cell divisions

Ahead of World Cancer Day on 4 February, scientists are revealing a cutting-edge artificial intelligence (AI) tool designed to help grade cancer, by analysing cell division.

News • Focus on autoreactive T lymphocytes

Guillain-Barré Syndrome: researchers find cause

The underlying mechanisms of Guillain-Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.

Article • Next-generation pathology

Multiplexed staining techniques in the fight against complex diseases

Bringing digital pathology together with novel multiplexed staining techniques may answer key questions about complex diseases. Pathologist Lukas Marcelis, MD, PhD, believes such combinations of technology will have benefits for clinicians and patients and can help unravel some of the mysteries surrounding a range of conditions.

News • Friend and foe in one

Breast cancer: The paradoxical role of white blood cells

White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.

News • Unexpected behaviour

Pathogens can force their way through the immune defense, new study shows

Breaking & entering – on a minuscule scale: US researchers have shown how some pathogens like Toxoplasma can enter cells using physical force to cause an infection.

News • WSI-based analysis

AI-driven classification of diffuse gliomas skips molecular testing

Research from Shenzhen proposes an integrated diagnosis model for automatic classification of adult-type diffuse gliomas directly from annotation-free standard whole-slide pathological images.

Article • Infection control

The strain typing technologies of tomorrow

Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.

News • Deep learning refinement

Colorectal cancer: AI tool improves diagnostic accuracy

Researchers from Finland have developed an artificial intelligence tool for automatic colorectal cancer tissue analysis that outperforms prior methods.

News • Biomarker-based predictions

AI drives precision oncology for colorectal cancer

For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).

Article • Breast cancer diagnostics

Precision pathology: an AI-led alternative to molecular diagnostics

Experts have highlighted how precision pathology using Artificial Intelligence can provide an effective alternative to molecular diagnostics. This, say a team from the Karolinska Institutet (KI) in Stockholm, Sweden, can also offer multiple advantages within a clinical setting and support risk stratification.

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