Pathology

News • Cell-free tumor DNA analysis

Liquid biopsy to unlock breast cancer treatments

New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.

News • Study explores impact

How brain trauma can trigger Alzheimer's disease

Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.

News • Reactive glial responses

Mapping the brain's self-healing ability after stroke

Helping the brain repair itself after a stroke: A new study based on unique tissue samples from Denmark's Brain Bank may pave the way for new treatments that support brain regeneration.

News • Promising prototype

A “diagnostic wand” to detect oral cancer

Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.

Article • Keynote on integrated diagnostics

Predicting – and shaping – the future of modern pathology

Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in…

News • Advances in precision medicine

MASLD: Research reveals two types of fatty liver disease

Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.

MEDIPATH makes a step towards lab automation with the help of Sakura Finetek Europe

Sakura Finetek Europe and MEDIPATH, a group of independent French pathologists, announced their collaboration to enhance cancer diagnostics and thus contribute to improved patient therapeutic management. This decision is part of an ongoing commitment to improving the quality of care provided to patients and in response to the significant increase in cancer cases over the last years.

News • Tumour movement across tissues

Understanding metastasis: migration strategies of ovarian cancer

A new study shows how inherent variations in a cancer cell and its interactions with its surroundings mould its migration. The findings provide valuable insights into the processes behind metastasis.

Article • Between good practice and financial pitfalls

Delivering molecular pathology at lower costs

Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.

News • Insights into tumor biology

Breast cancer: Exploring metastasis diversity

In many cases, metastatic breast cancer is still incurable. To improve the odds, researchers have now analyzed the diversity of metastatic cells and their interactions with their cellular environment.

News • Single-cell metabolic profiling

Mass-spec and IMC give deep insights into tumors

By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.

Process tissue continuously, safely, and in a standardised way while speeding up your throughput

Sakura Finetek’s Tissue-Tek Xpress® x120 Rapid Tissue Processor is the only instrument on the market that allows for continuous, rapid processing of both biopsy and larger tissue, resulting in a streamlined histology workflow. Being part of Sakura’s SMART Automation concept, this tissue processing solution is designed to automate manual work and create a continuous flow throughout the lab. 

News • Achieving and maintaining high service quality

QA in histopathology laboratories from pre- to post-analytic phase

Testing from histopathology laboratories is considered the gold standard for many diseases. To avoid errors that can significantly impact patient outcomes, an expert details on quality assurance (QA).

News • Color adjustment technique

Digital pathology: AI platform to improve lung cancer diagnosis

Cologne researchers have developed an AI-based digital pathology platform to enable extremely fast and accurate fully automated analysis of tissue sections from lung cancer patients.

News • Tailored chatbot

Customized ChatGPT to advance digital pathology

New research shows that the AI large language model ChatGPT can be tailored to provide accurate responses to questions about digital pathology and compile detailed results.

News • Tumour infiltrating lymphocyte measurement

Breast cancer: AI tool predicts which DCIS cases become invasive

Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.

Article • Challenges and opportunities

Molecular pathology in Europe: in search of standardization

Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.

News • Infectious disease diagnostics

POCT for remote areas: Portable pathology passes the test

When point-of-care testing (POCT) models for diagnosing infectious disease are effective, the quality of pathology results can be equivalent to laboratory tests, new research shows.

Leaping forward with laboratory workflow automation

Embark on a journey of unparalleled efficiency and precision with Sakura Finetek Europe's newest innovation in identification technology: the Tissue-Tek xPrint® LP Laser Cassette Printer.

News • Neuropathology

Technology offers new insights into pediatric brain tumors

A new study used new molecular analyses to unravel the biological mechanisms of pediatric brain tumors and refine their classification.

Article • Pros and cons of diagnostic techniques

Liquid biopsy vs. tissue biopsy: Getting the best of both worlds

Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.

News • Three-dimensional tissue processing

Pathology performs leap into 3D with AI

Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.

News • Research on large foundation models

Reducing bias in pathology AI

A study highlights performance differences in computational pathology systems, depending on demographic profiles associated with histology images. The researchers also propose a way to fix this bias.

News • Pathology solutions provider

Jaap Stuut appointed as Sakura Finetek President

Sakura Finetek Europe has appointed Jaap Stuut as the President and General Manager. He will lead the company's EMEAI division in this role, shaping the its mission, vision, and long-term strategy.

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