Pathology

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News • Histological transformation

How lung cancer can transform into another type

Under certain circumstances, lung tumours can transform into another, more aggressive cancer type. Now, researchers have found a way to illuminate this process, known as histological transformation.

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News • Mitosis profiling

AI tool helps grade cancer based on cell divisions

Ahead of World Cancer Day on 4 February, scientists are revealing a cutting-edge artificial intelligence (AI) tool designed to help grade cancer, by analysing cell division.

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News • Focus on autoreactive T lymphocytes

Guillain-Barré Syndrome: researchers find cause

The underlying mechanisms of Guillain-​Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.

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Article • Next-generation pathology

Multiplexed staining techniques in the fight against complex diseases

Bringing digital pathology together with novel multiplexed staining techniques may answer key questions about complex diseases. Pathologist Lukas Marcelis, MD, PhD, believes such combinations of…

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News • Friend and foe in one

Breast cancer: The paradoxical role of white blood cells

White blood cells found in breast tumors can both help and hinder the spread of cancer cells to other organs, a new study from Karolinska Institutet shows.

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News • Unexpected behaviour

Pathogens can force their way through the immune defense, new study shows

Breaking & entering – on a minuscule scale: US researchers have shown how some pathogens like Toxoplasma can enter cells using physical force to cause an infection.

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Article • Infection control

The strain typing technologies of tomorrow

Cedars-Sinai Medical Center, a non-profit hospital and medical research institution in Los Angeles, is setting new standards for quality and innovation in patient care by successfully introducing typing of Candida auris species – a procedure that could prove crucial in protecting patients from infection outbreaks caused by these microbes in healthcare settings.

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Article • Confirming initial positive findings

First-tier rapid serology testing for Lyme disease

Lyme disease, the most common tick-transmitted bacterial infection in the world, is challenging to diagnose. Initial early-stage symptoms may include skin rash, fever, headache, fatigue, swollen lymph nodes, and/or body and joint aches. However, these symptoms are also associated with many other diseases and medical conditions.

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