Research

Dr Ari Melnick

A new chapter in leukaemia and hematologic disease research

Dr Ari Melnick has been appointed the new Director of the Josep Carreras Leukaemia Research Institute by the Board of Trustees. The institute specialises in biomedical research and precision medicine…

News • Prognostic role of IPMNs

Nodules key to avoid unneccessary pancreatic cancer surgery

Pancreatic cysts (IPMNs) are seen as a precursor of pancreatic cancer. However, not all patients need to undergo surgery. A recent study may help patients with IPMNs to avoid unnecessary surgery.

News • Else Kröner Excellence Grants 2025

Building bridges for US medical researchers

Working conditions for scientists in the field of medicine are becoming increasingly difficult in the USA. A new funding initiative offers outstanding scientists a new perspective in Germany.

News • Plasmonic nanorods

Golden eyes: restoring vision with nanoparticles

A new study suggests that gold nanoparticles — thousands of times thinner than a human hair — might one day help restore vision in people with macular degeneration and other retinal disorders.

News • Bioengineered scaffolds

New hydrogel to improve CAR T immunotherapy

Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.

News • Measuring neonatal pain

Pain assessment in newborn babies: current scales lack evidence

In an NICU, it is critically important to accurately assess a baby's pain level. A new review finds that none of the current clinical rating scales are backed by evidence in terms of validity…

News • Mechanopathology

'Dengue-on-a-chip' to study infection mechanisms

Due to the effects of climate change, dengue is spreading worldwide. Now, researchers have developed a 'dengue-on-a-chip' model that helps study the virus more effectively.

News • Spatial transcriptomics and proteomics profiling

Researchers explore post-stroke brain reperfusion

Researchers have succeeded in mapping how blood vessels in the brain react after a stroke. This new insight can lead to more effective treatment and fewer complications for patients.

News • Pulsed infrared light to enhance diagnostics

Finding the ‘fingerprints’ of cancer

New research reveals a method that uses pulsed infrared light to identify molecular profiles in blood plasma that could indicate the presence of certain common cancers.

News • Brain MRI analysis

AI tool tracks effectiveness of multiple sclerosis treatments

A new AI tool can extract key information from brain MRI scans of multiple sclerosis (MS) patients. This could be used to improve disease and treatment response monitoring.

Anastasia Khvorova, PhD

Pioneering work in the field of RNA-based therapies for Huntington's disease

RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.

News • Study on Staphylococcus aureus

Understanding bacterial antiviral defenses to tackle antibiotic resistance

In a new study, researchers show that the emergence of antibiotic resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses.

News • Swedish national initiative

Precision omics to boost data-driven medicine

The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.

News • Self-sustaining thermoelectric system

e-Tattoo detects infections from skin temperature

An international research team has developed an intelligent device capable of monitoring the skin continuously and accurately detect temperature variations associated with inflammation and infection.

News • Targeting early versions

A 'head start' in the race against pancreatic cancer

Fighting pancreatic cancer can feel like a race against time. A new discovery could give clinicians a head start - by targeting precancerous lesions before they become much more aggressive.

News • Lifestyle-related disease prevention

Soccer: an underrated champion of global health

Soccer is not only a fun and popular sport, but can also help prevent many lifestyle-related conditions, including diabetes, heart disease, obesity, several cancers, and mental health challenges.

News • Double Stokes polarimetric microscopy

New method to help accelerate cancer diagnosis

A new method to quickly and accurately analyze the structure of collagen in tissue shows promise to improve the diagnostics of cancer and other diseases.

News • Light-activated device

World's tiniest pacemaker can be injected into body, dissolves after use

Smaller than a grain of rice: US engineers have developed a pacemaker so tiny that it can fit inside the tip of a syringe — and be non-invasively injected into the body.

News • Landmark surgery trial

Gastric bypass, sleeve or band? Study weighs up surgical options for severe obesity

Severe obesity comes with serious health risks, which can be reduced with metabolic and bariatric surgery. Now, a landmark study reveals which operation is most effective or cost-effective.

News • Systemic cell rewiring

How midkine helps tumours evade immunotherapy

Researchers discovered a key mechanism by which melanomas and other aggressive tumours prevent the immune system from detecting and attacking them – one of the greatest challenges in oncology today.

News • Alleviating inflammatory skin disorders

Microneedles to speed up diabetic wound healing

Researchers have developed ‘sponge-like’ microneedle patches that deliver bioactive ingredients and reduce inflammation in slow- and non-healing diabetic wounds.

News • Extracellular microenvironments

Advancing diabetes treatment with 3D bioprinting

Leveraging bioink from pancreatic tissue and 3D bioprinting, researchers developed a structure closely mimicking the structure of a pancreas, in which cultured cells can resume insulin production.

News • 2025 TB surveillance and monitoring report

Childhood tuberculosis up by 10%: a wake-up call for Europe

Transmission of tuberculosis (TB) in the European Region is still ongoing, and immediate public health measures are needed to control and reduce the growing burden of the disease, experts urge.

News • Review of colonoscopy CADe systems

AI for colon cancer detection: "Right now, this is version 1.0. We need version 4.0”

A rigorous review of evidence showed that AI-assisted technology helps identify colorectal polyps. However, its impact on preventing colon cancer remains unclear.

Maartje Huijbers

Combining research work and vice dean duties

As of May 1st, Maartje Huijbers holds the position of vice dean of research, a new position within the Leiden University Medical Center (LUMC). Huijbers is associate professor and research group leader in the Department of Human Genetics and the Department of Neurology. She will combine her work as a scientist with the position of vice dean.

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