Can patients with high anatomic risk but low genomic risk for early-stage ER+/HER2- breast cancer do similarly well without chemotherapy? A new trial aims to evaluate the benefits for this subgroup.
A Cambridge study reveals how tumours suppress immune responses – and how blocking this mechanism could make immunotherapies effective in more patients.
To fight cystic fibrosis at the source, scientists have both identified a key infection mechanism and a way to correct the defect. Their insights could help limit serious complications in CF patients.
A research team has developed a new class of protein-based MRI contrast agent that detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.
Radiotherapy may be able to do far more than simply destroy tumor cells. A review explores how combining radiotherapy with immunotherapy could improve outcomes for patients with pancreatic cancer.
A new study shows that phage therapy could help reduce recurrent infections, which happen when the bacteria responsible for UTIs ‘hide’ in the tissue of the bladder.
Deliberate laughter therapy offers an effective low-cost complementary treatment to help patients with COPD reduce breathing difficulties at home without specialist support, new research finds.
People with lung cancer are more likely to have microplastics in their lungs and to have larger quantities of microplastics in their lungs, according to new research.
A new study sheds light on the complex competition and cooperation between bacteria in the gut microbiome. These insights could be leveraged for targeted manipulation of the microbiome.
Using a specialized “broth”, researchers have developed a way to condense the days-long diagnosis timeline for sepsis to just hours, facilitating faster diagnosis and clinical decision-making.
This small patch contains tiny microneedles that can gently pass through the outer layer of the skin without drawing blood, to deliver two anti-cancer drugs for localised skin cancer treatment.
Researchers have found an ‘immune organ’ inside the skull, which directs brain defenses. The findings may offer a new way to fight brain cancer and neurodegenerative diseases.
Cancer metastasis is responsible for at least two-thirds of cancer deaths. Researchers have developed a multi-organ chip that mimics how cancer cells spread to distant organs to gain new insights.
New research has identified a previously unknown mechanism of Kabuki syndrome, a rare genetic disorder. The discovery could open new therapeutic perspectives.
On the way to a patient's “digital twin”: A novel, AI-powered virtual patient simulation system integrating multimodal data is designed to advance personalised cancer treatment.
Researchers identified a possible biomarker linked to severe suicidal thoughts. It may also help explain why some people recover, opening a new path for research into resilience and prevention.
In the DISCOVER-ME project, researchers search for biological characteristics of myalgic encephalomyelitis, and also investigate whether patients can be divided into different subgroups.
Digital pathology and spatial omics could enable researchers to see how a tumor's different cell populations function, opening new perspectives for precision cancer therapy.
Researchers warn that droughts could make humans and wildlife more vulnerable to certain infectious diseases, leading to surges in illnesses like cholera and West Nile virus around the world.
