Therapy

News • Genicular artery embolization

Lasting relief for knee pain – without surgery

For patients with knee osteoarthritis, for whom injections no longer provide sufficient relief, but joint replacement is also not an option, a minimally invasive treatment might offer an alternative.

News • Temporal interference stimulation

Towards deep brain stimulation without surgery

A promising technology enables deep brain stimulation without the need to surgically implant electrodes. This could pave the way for its use in the treatment of neurological and psychiatric disorders.

News • Novel radiopharmaceutical therapy

Promising treatment option for aggressive neuroendocrine tumors

A new type of peptide receptor radionuclide therapy (PRRT) appears to be safe in metastatic neuroendocrine tumor patients who have exhausted conventional treatment options.

News • Targeted immunotherapy

Implantable cytokine factories to help treat ovarian cancer

Researchers have reported results from a first-in-human trial evaluating a novel cell-based platform for localized delivery of interleukin-2 (IL-2) in patients with advanced ovarian cancer.

News • Research

CRISPR tool targets cancer and virus-infected cells precisely

A CRISPR-based tool called Cas12a2 can selectively eliminate cancer and virus-infected cells based on their RNA signature – with high precision and no off-target effects.

News • Oncology

Nanozymes take on brain tumours from the inside

Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.

News • mRNA-based strategy

Cystic fibrosis: new study identifies gene therapy

Now, a new study identified a gene therapy for individuals with cystic fibrosis (CF) caused by a specific mutation and for whom there was no treatment available until now.

News • Bone healing ‘superpower’

Wrist fracture in children: Trial favours cast-first approach

Most children with a broken wrist can be treated without surgery, a major trial finds, suggesting that a cast-first approach delivers similar long-term recovery while reducing risks and costs.

News • Prediction of treatment response

Colon and rectal cancer: new biomarker shows which patients benefit from immunotherapy

A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.

News • Endovascular therapy

Simple stent procedure can treat post-thrombotic syndrome

A clinical trial has shown that post-thrombotic syndrome — a common and often painful complication after deep vein thrombosis — can be effectively treated with a minimally invasive procedure.

News • PARP inhibitors distribution

“Hidden drug storehouses” could explain treatment resistance in cancer

Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.

News • Triple-negative breast cancer

TNBC can become treatment-resistant in more ways than one

About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.

News • Treatment approach

How to improve cancer cure rates? “Kick it while it’s down”

Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.

News • Promising trial results from Spain

Clot-dissolving drug after thrombectomy may improve stroke recovery

Even after a blood clot is removed from a large brain artery via thrombectomy, administering the thrombolytic drug alteplase to the area may improve stroke recovery, a new trial from Spain shows.

News • Cardiac ablation techniques compared

Atrial fibrillation: Study makes economic case for pulsed field ablation

A new European study suggests that PFA may offer hospitals a way to treat atrial fibrillation more efficiently – with shorter procedures and lower costs than established methods.

News • Disease tolerance and infection pathogenesis

Different age, same infection treatment? Not a good idea, study finds

Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.

News • Focus on tumor STAT1 acetylation

How cancer cells learn under pressure to evade immunotherapy

Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.

Article • Personalised medicine

Gene-editing technologies: from lab to patient

Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…

News • Acellular dermal matrix for breast reconstruction

Injectable breast ‘implant’ as alternative to surgery

Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.

News • Prevention of unnecessary emergency admissions

Mobile Stroke Units could reduce pressure on healthcare systems, study finds

Mobile Stroke Units, equipped with a CT scanner, point-of-care laboratory, and communications capabilities, could reduce unnecessary emergency department transfers by 86%, a new study finds.

News • Prevalence, changes and associated factors

How to reduce the risk of head and neck lymphedema after radiotherapy

Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.

News • Between the heart and the brain

Why cardiovascular disease and depression often develop together

Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.

News • CAR-T and BITEs

At-home monitoring safely cuts hospital time after T-cell redirecting therapy

After T-cell redirecting therapies, patients are typically hospitalized for several days to watch for side effects. New research shows that these patients can safely be monitored at home.

News • Malignant melanoma

Immunotherapy for skin cancer: when less is more

New immunotherapies are effective against skin cancer, but they can cause serious side effects. New insights suggest that a lower dosage may lead to better outcomes and longer survival.

News • New decision making framework

BAt: Towards precision medicine for COPD

A European consortium has developed a new decision making framework for health professionals which they hope will transform the care of patients with chronic obstructive pulmonary disease (COPD).

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