Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.
Not all PCOS is the same: Researchers identified four subgroups with distinct symptoms and different responses to treatment – opening the door to precision medicine for millions of women worldwide.
Many doctors shy away from discussing the aspect of a treatment's sustainability with their patients, expecting a negative reaction. Now, a new study suggests that these fears may be unfounded.
Breast cancer survivors are often discouraged from undergoing hormone replacement therapy (HRT) to alleviate menopause symptoms. Now, new research paints a more differentiated picture.
University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.
The number of patients with substance abuse disorders who are admitted to hospitals as inpatients has been steadily increasing. Hospitalists attending SHM Converge 2025, the annual meeting of the Society of Hospital Medicine (SHM) in Las Vegas this spring, were given practical advice on how to treat these patients.
German researchers discover how HIV selects genome integration targets using RNA:DNA hybrids as guides, revealing new therapeutic approaches for controlling viral reservoirs.
People with both type 2 diabetes and obstructive sleep apnoea have a higher risk of death, but treatment with CPAP may reduce that risk by around 26%, a new study finds.
In metastatic EGFR-mutated non-small cell lung cancer (NSCLC), targeting residual disease through surgery can extend the benefits of EGFR TKI therapy beyond standard monotherapy, a new study finds.
Researchers explored two promising new biomarkers as potential radiotheranostic targets for endometrial cancer. This could help identify patients who are likely to respond to targeted therapeutics.
Currently, cancer treatment evaluation focuses heavily on survival outcomes, but doesn't adequately consider how treatments affect quality of life. A new policy review aims to change this.
From active monitoring to combinations of local and systemic treatment: A new study shows that most men with prostate cancer who receive treatment recommended by guidelines have a good prognosis.
Tongue squamous cell carcinoma, the most common type of oral cancer, is a challenging target for immunotherapies. Researchers now identified five immunotypes to better predict treatment response.
Radiation therapy is an effective component of many cancer treatments, but some patients experience severe side effects. A new study shows that hyperbaric oxygen therapy can provide long-term relief.
Arginine vasopressin deficiency (AVP-D) is a rare condition affecting the body's water management. However, it is also known under a different name – this can lead to fatal mix-ups.
Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.
World TB Day raises awareness about tuberculosis and commemorates the discovery of the source bacterium M. tuberculosis. More than a century later, scientists still refine anti-TB strategies.
Cryoablation, the destruction of malignant cancer cells by freezing them, is increasingly becoming an alternative to having conventional lumpectomy for patients diagnosed with early-stage, localised, low-risk breast cancer. Findings from numerous recent clinical trials show that cancer recurrence rates are very low and are comparable to breast conservation surgery (BCS).
The boom in interventional radiology procedures has enabled great strides in ischemic stroke management. But while a myriad of techniques are available, the challenge remains in choosing the most appropriate thrombectomy treatment on the spot, according to Jordi Blasco Andaluz, a neuroradiologist at Hospital Clinic Barcelona. The new ROSSETTI registry is designed to change this.
