Keyword: therapy

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Biomedical engineering

Cornea restoration: Scientists develop physical biomarker

Our eyes – considered by many to be the windows to the soul – need constant care, and as we age, they sometimes also need significant repair. The panes of these windows – the corneas – are transparent tissues that have been the focus of some of the oldest and most common transplantation surgeries. Now thanks to researchers in Kyoto, some such transplants may become even safer. The team,…

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Global health

WHO updates list of essential medicines and diagnostics

The World Health Organisation's (WHO) Essential Medicines List and List of Essential Diagnostics are core guidance documents that help countries prioritize critical health products that should be widely available and affordable throughout health systems. Now, updated versions of the two lists have been published, focusing on cancer and other global health challenges, with an emphasis on effective…

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"Bless you!"

Common cold virus could revolutionise bladder cancer treatment

A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer. No trace of the cancer was found in one patient following treatment with the virus. The researchers published their findings in the medical journal Clinical Cancer Research. Researchers from the University of Surrey and Royal Surrey County Hospital investigated…

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Oncology

Response to gene-targeted drugs depends on cancer type

Cancers with the same genetic weaknesses respond differently to targeted drugs depending on the tumour type of the patient, new research reveals. The study is set to prompt changes in thinking around precision medicine—because it shows that the genetics of a patient's cancer may not always be enough to tell whether it will respond to a treatment. The researchers are already starting to design…

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Photonics

Rapid tissue analysis: Laser light detects tumors

Cancer - this diagnosis affects almost every second German at some point in his life. It is the second most frequent cause of death in Germany. But the earlier the disease is diagnosed, the greater are the chances of surviving it. A team of researchers from Jena present a groundbreaking new method for the rapid, gentle and reliable detection of tumors with laser light at the leading trade fair…

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Boosting our immune surveillance

Antibodies PD-1 and PD-L1: a quantum leap in cancer therapy

Immuno-oncology is a therapy in which the body’s immune system treats a tumour. Dr Eric Borges, from the Research and Development Centre at Boehringer Ingelheim Pharma GmbH in Germany, explains why this is revolutionary. Unlike conventional cancer therapies, with immuno-oncology the tumour cell is not the direct target, it’s the patient’s immune system. The medication stimulates this to…

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Macular Degeneration

Implanted drug ‘reservoir’ reduces injections

In a clinical trial of 220 people with “wet” age-related macular degeneration, Johns Hopkins Medicine researchers, collaborators from many sites across the country, and Genentech in South San Francisco have added to evidence that using a new implant technology that continuously delivers medication into the eyes is safe and effective in helping maintain vision and reduces the need for…

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Microsatellites

Stomach and colorectal cancer: AI identifyies patients for immunotherapy

Changes in certain sections of the genetic material of cancer cells, so-called microsatellites, can provide an important indication of whether immunotherapy may be successful in a patient with stomach or colorectal cancer. Scientists from Uniklinik RWTH Aachen, the German Cancer Research Center (DKFZ), the German Cancer Consortium (DKTK) and the National Center for Tumor Diseases Heidelberg (NCT)…

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Oestrogen-receptor positive, HER2-negative

Test determines most effective treatment for breast cancer

A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK. The test was successful in predicting whether chemotherapy would be beneficial for patients with the most common type of breast cancer (oestrogen-receptor positive, HER2-negative),…

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Women's health

Endometriosis: Antibiotic could be key to treatment

Researchers at Washington University School of Medicine in St. Louis have found, in mice, that treatment with an antibiotic reduces the size of lesions caused by endometriosis. The researchers are planning a large, multicenter clinical trial to test the drug metronidazole in women who have the painful condition. The study is published online April 30 in the journal Human Reproduction.…

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Research

Promising new stroke therapy in development

Researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have developed a novel stroke therapy that, when tested in mice and dogs, has proven superior to the standard of care therapy now offered to patients suffering a stroke. Findings of the study are published online in Molecular Therapy. “We have shown that our drug, which is completely…

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Personalized medicine

FDA approves first targeted therapy for metastatic bladder cancer

The U.S. Food and Drug Administration (FDA) granted accelerated approval to Balversa (erdafitinib), a treatment for adult patients with locally advanced or metastatic bladder cancer that has a type of susceptible genetic alteration known as FGFR3 or FGFR2, and that has progressed during or following prior platinum-containing chemotherapy. Patients should be selected for therapy with Balversa…

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Obsessive compulsive disorder

Targeted deep brain stimulation reduces OCD symptoms

The debilitating behaviours and all-consuming thoughts which affect people with severe obsessive compulsive disorder (OCD), could be significantly improved with targeted deep brain stimulation, according to the findings of a new study. OCD is characterised by unwanted intrusive thoughts (obsessions) and repetitive stereotyped behaviours (compulsions- sometimes called rituals) and often means…

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Simplified catheter ablation

“Back to basics” atrial fibrillation procedure could cut waiting lists

A day case catheter ablation procedure which includes only the bare essentials and delivers the same outcomes could slash waiting lists for atrial fibrillation patients, according to late-breaking results from the AVATAR-AF trial presented today at EHRA 2019, a European Society of Cardiology (ESC) congress. With the simplified protocol, 30% more patients could receive catheter ablation for the…

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Some problems remain

Some children can 'recover' from autism

Research in the past several years has shown that children can outgrow a diagnosis of autism spectrum disorder (ASD), once considered a lifelong condition. In a new study, researchers at Albert Einstein College of Medicine and Montefiore Health System have found that the vast majority of such children still have difficulties that require therapeutic and educational support.

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Stop progression

Weight loss sets back Type 2 diabetes for at least two years

More than a third of people with Type 2 diabetes who took part in a weight management programme delivered by the NHS through GP surgeries remain free of diabetes two years later. These latest findings of the Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and led by experts at Newcastle University and the University of Glasgow, were announced today at Diabetes UK’s…

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Gastroenterology

'Hypnotising' Skype therapy helps irritable bowel

Skype hypnotherapy is an effective treatment for people with severe irritable bowel syndrome, a new study has found. The study of 20 patients who had the treatment via the online communications tool was led by Professor Peter Whorwell from The University of Manchester It is published in the International Journal of Clinical and Experimental Hypnosis. Professor Whorwell is a gastroenterologist at…

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