Keyword: therapy

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HER2 breast cancer

‘Soft’ chemotherapy plus targeted treatment spell new hope for elderly patients

Avoidance of side-effects of chemotherapy is particularly important in the elderly, but finding the balance between reduced toxicity and maximum effectiveness is not always easy. A trial carried out by the European Organisation for Research and Treatment of Cancer, published in The Lancet Oncology, shows that, in older patients with HER2 positive metastatic breast cancer (an aggressive breast…

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TCAR (Transcarotid artery revascularization)

Reversing blood flow reduces stroke risk during carotid artery procedure

Loyola Medicine is the first academic medical center in Illinois to use the TCAR system, which reduces stroke risk during carotid artery procedures by temporarily reversing blood flow. Carotid arteries on each side of the neck supply blood to the brain. In patients with carotid artery disease, a build-up of plaque can cause blockages. A common method to open the artery involves a balloon…

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Interactive tool

Breast cancer: Improving patient knowledge of treatment options

Breast cancer patients face complex decisions about their treatment. “Knowledge is a key component of decision making, and yet it’s consistently low even among patients who have received treatment. We need better tools to make these decisions more informed,” says Sarah T. Hawley, Ph.D., MPH, professor of internal medicine at Michigan Medicine. Hawley and colleagues from the Cancer…

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Microbubbles

Bracco Imaging to innovate ultrasound for new personalized gene therapy

Bracco Imaging S.p.A., a global leader in diagnostic imaging, announced that it has initiated new experimental activities in its R&D Center in Geneva, Switzerland, to explore a new application for gas-filled microbubbles in the development of personalized gene therapy for treatment of chronic dysfunctional diseases related to lipid metabolism. Microbubbles have already revolutionized medical…

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Antiviral design

CAR-T gene therapy could provide long-term HIV protection

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells not only destroyed the infected cells, they persisted for more than two years, suggesting the potential to create long-term immunity from the virus…

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Cooperation

Hitachi to install new proton beam therapy system in Spain

Hitachi, Ltd. announced that it has entered into an agreement to provide Clinica Universidad de Navarra (CUN) with its proton beam therapy (PBT) system. The agreement includes PBT system maintenance following completion of the systems' installation. The PBT System will be installed at CUN's facility in Madrid, Spain and is equipped with state of the art technology including spot scanning…

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Ventricular tachycardia

Deadly heart rhythm halted by noninvasive radiation therapy

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients who had irregular heart rhythms, called ventricular tachycardia, at the School of Medicine. The patients…

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A double-edged sword

Killing cancer cells can also drive tumor growth

Cancer therapies including radiation and chemotherapy seek to treat the disease by killing tumor cells. Now a team including researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown that the dead and dying cancer cells generated by chemotherapy and targeted cancer therapy paradoxically trigger inflammation that promotes aggressive tumor growth. In a study published today in the…

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Cell activity

Individual receptors caught at work

G protein-coupled receptors (GPCRs) are among the "hottest” targets for the therapy of diseases such as hypertension, asthma or Parkinson's. These receptors are the site of action of many hormones and neurotransmitters and allow them to regulate the activity of our cells. How and where this happens has long been the subject of numerous hypotheses. An international team of scientists from…

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Rheumatoid arthritis

Hibernation causes inflammation

A research team found that in patients suffering from rheumatoid arthritis, a special cell population called innate lymphoid cells are in a state of hibernation which is why these patients suffer from persistent inflammation.

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Long-term support

Stroke: Lethal risk even without complications

People who survive a stroke or a mini-stroke without early complications have an increased risk of death, another stroke or heart attack (myocardial infarction) for at least 5 years following the initial stroke, found a new study published in the Canadian Medical Association Journal.

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Integrated quality assurance

IBA releases the newest version of myQA global platform

IBA (Ion Beam Applications S.A.), the world’s leading provider of proton therapy solutions and radiation therapy integrated quality assurance (QA) for the treatment of cancer, announces the release of myQA version 2017-001. This new version further enhances the integration of quality assurance across all QA applications, departments and people.

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DNA manipulation

Chaos in cancer cells: Mysterious gene transcripts after therapy

Drugs that are used in cancer therapy to erase epigenetic alterations in cancer cells simultaneously promote the production of countless mysterious gene transcripts, scientists from the German Cancer Research Center (DKFZ) now report in Nature Genetics. The substances activate hidden regulatory elements in DNA. The unusual gene activity has the potential to stimulate the immune system – a…

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Rare disorder

New treatment fot kidney failure patients

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

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Distribution

Grabbing multiple sclerosis by the nose

Over the next few years, in a research project funded by the EU, an international consortium is developing a new technology for a better treatment of multiple sclerosis. The idea of the innovative “Nose2Brain” approach is to transport a special active substance directly through the nose into the central nervous system.

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Going Viral

An unusual 'friend' to help fight ovarian cancer

In some cases, the Lassa virus starts with a fever and general weakness, moving toward headache, muscle pain, possible facial swelling, deafness, and worse. About 15 percent of patients hospitalized with severe cases die. Lassa fever is contagious, endemic in West Africa, and Dr. Anthony van den Pol thinks he can use it to cure ovarian cancer.

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