Researchers have reported results from a first-in-human trial evaluating a novel cell-based platform for localized delivery of interleukin-2 (IL-2) in patients with advanced ovarian cancer.
A CRISPR-based tool called Cas12a2 can selectively eliminate cancer and virus-infected cells based on their RNA signature – with high precision and no off-target effects.
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.
Now, a new study identified a gene therapy for individuals with cystic fibrosis (CF) caused by a specific mutation and for whom there was no treatment available until now.
Most children with a broken wrist can be treated without surgery, a major trial finds, suggesting that a cast-first approach delivers similar long-term recovery while reducing risks and costs.
A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.
A clinical trial has shown that post-thrombotic syndrome — a common and often painful complication after deep vein thrombosis — can be effectively treated with a minimally invasive procedure.
Why do some cancer cells develop treatment resistance? The answer may lie in hidden “storage hubs” inside tumour cells, which create uneven drug exposure across tumours, according to new research.
About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.
Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.
Even after a blood clot is removed from a large brain artery via thrombectomy, administering the thrombolytic drug alteplase to the area may improve stroke recovery, a new trial from Spain shows.
A new European study suggests that PFA may offer hospitals a way to treat atrial fibrillation more efficiently – with shorter procedures and lower costs than established methods.
Should younger and older people receive different treatments for the same infection? New research suggests that age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.
Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…
Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.
Mobile Stroke Units, equipped with a CT scanner, point-of-care laboratory, and communications capabilities, could reduce unnecessary emergency department transfers by 86%, a new study finds.
Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.
Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.
