Cells

News • Aldosterone-producing adenomas

The surprising complexity of adrenal gland tumors

New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.

News • Alteration of immune response

Multiple myeloma: dangerous diversity

When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.

News • Researcher reveals vulnerability

New approach to crack persister tumour cells

Persister cells arise as a result of cancer treatment and are often responsible for tumour relapse. Researchers identified a distinctive feature of persister cells, paving the way for new treatments.

News • Pyroptosis propagation

Sepsis, or death by lethal message

Dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues report. Their findings could lead to a new understanding of this dangerous illness.

News • Molecular mechanism discovered

Researchers find a way to stop harmful cells after cancer treatment

Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.

News • Industry collaboration

Developing “acoustic beads” for advanced rare and complex cell sorting in flow processes

Acoustofluidics company Aenitis Technologies has entered a Memorandum of Understanding (MOU) with pharmaceutical company Bracco Imaging to develop next-generation acoustic microspheres.

News • Immunology

Researchers discover new type of anticancer T-cell

A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.

News • Inclusion of all cell lineages

Advanced pancreas organoid for better insights

A new type of pancreas organoid contains all key pancreatic cell types - acinar, ductal, and endocrine cells - allowing valuable new insights.

News • Dermatology

Exploring fibroblast subtypes and skin cancer aggressiveness

New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.

News • New insights on aneuploid epithelial cells

Breast cancer-like cells also found in healthy women

A certain type of cells, called aneuploid epithelial cells, are usually associated with breast cancer. However, new research reveals that they can also be found in healthy women.

News • Exploring potential and limitations

Bedside bioprinting: the future of regenerative medicine?

To take cell therapy in regenerative medicine to a new level, experts consider 3D bioprinting a key technology. However, there are still quality issues that need to be overcome to achieve this.

News • Microgravity-induced changes

How cancer cell cultures in space can help defeat cancer on Earth

New insights gained from 3D cell cultures of breast and prostate cancer grown on the International Space Station (ISS) National Laboratory could lead to a way to treat not just these but all cancers.

News • Research on "double strike" mechanism

Induction of defective cell division could improve blood cancer therapy

Tumor cells are notorious for their rapid and uncontrolled division, and many cancer therapies aim to disrupt this. New findings suggest potential applications of apoptosis in blood cancer treatment.

News • Hibernation

Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold

A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.

News • DNA damage response

New insights into the DNA damage response

The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.

News • Single-cell metabolic profiling

Mass-spec and IMC give deep insights into tumors

By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.

News • Reducing chemotherapy side effects

Trapping cancer cells in molecular 'cages'

Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.

News • High-resolution cell scans

AI spots cancer and viral infections at nanoscale precision

Researchers have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

News • Synthetic nanofibers

Repairing cartilage damage with ‘dancing’ molecules

US researchers applied an injectable new therapy, which harnesses fast-moving “dancing molecules,” to repair damaged human cartilage cells within just 4 hours.

News • Adaptive mutability

How bowel cancer flips the switch to avoid immune detection

Why does the immune system sometimes fail to control the development of bowel cancer? UK and Dutch researchers discovered how cancer cells use a genetic "switch" to evade detection.

News • Vital mechanism discovered

Promising approach to prevent breast cancer recurrence

Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.

News • Research on immune system responses

Allergy or infection? Scientists discover distinguishing features

Scientists discover how the production of antibodies is regulated in allergy and infections. This opens the door to new therapies, without affecting the beneficial response of the immune system.

News • Research on DNA danage

Surprise finding on cancer cell death to impact therapies

Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.

News • 6.5 million European funding

Fighting cancer with artificial cells and tissue

Artificial cells to combat cancer: Research groups are working to create synthetic micro-organisms capable of detecting the presence of the disease and delivering anti-cancer therapies.

News • Leukemia MRD after chemo

AML: Residual cancer testing as an important safeguard

Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.

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