Cells

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News • Amyotrophic lateral sclerosis

New insights on ALS onset opens paths to earlier treatment

New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.

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News • Spatial transcriptomics and ECM imaging

3D insights into the tumor microenvironment

Unprecedented insights into the inner workings of an early-stage lung tumor: An international research team describes a new method for 3D mapping cellular interactions in the tumor microenvironment.

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News • Interferon response cancer-associated fibroblasts

Pancreatic cancer: Cell discovery opens up new research avenues

A newly discovered type of cells counteract tumor development and may therefore be a target for research into new treatments for pancreatic cancer, which is one of the deadliest forms of cancer.

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News • Bioengineered scaffolds

New hydrogel to improve CAR T immunotherapy

Researchers developed biomimetic materials inspired by lymph nodes, which could improve cancer immunotherapy. The study highlights the potential of bioengineered scaffolds for cell-based therapies.

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News • Aldosterone-producing adenomas

The surprising complexity of adrenal gland tumors

New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.

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News • Alteration of immune response

Multiple myeloma: dangerous diversity

When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.

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News • Pyroptosis propagation

Sepsis, or death by lethal message

Dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues report. Their findings could lead to a new understanding of this dangerous illness.

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