Blood

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Autohaem smear and smear+

Automating blood smears for malaria diagnosis

Researchers have developed a device that removes one of the biggest bottlenecks preventing quick, reliable malaria diagnosis.

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Glioblastoma

Blood test for brain tumors possible

Researchers at the University of Sussex are one step further to developing a blood test capable of diagnosing the most aggressive form of brain tumour.

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Oncology

New blood test identifies if a patient has cancer

Researchers outline a new minimally invasive and inexpensive blood test that can identify cancer in patients with non-specific symptoms and whether these cancers have metastasised in the body.

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Diabetes

Microneedles: Nano-sized, huge impact

Drug delivery, blood extraction, contrast agent injection – many procedures in modern medicine would be utterly impossible without needles. Despite the benefits, inserting pointy metal tubes into a…

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Sponsored • DBS PEth analysis

Fully automated and hematoctrit corrected phosphatidylethanol analysis

The Swiss-based CAMAG DBS Laboratory in ­collaboration with the Institute of Forensic ­Medicine in Bern, Switzerland, has developed a novel approach for the fully automated analysis of the direct…

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Cancer research

Blood tests predict prostate cancer resistance to chemotherapy drug

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research…

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Drug delivery research

Nanoparticles to help cross the blood-brain barrier

Treating diseases such as Alzheimer’s or Parkinson’s is a challenge because drugs have to be able to cross the blood–brain barrier. As a result, the doses administered must be high and only a small fraction reaches the brain, which can lead to significant systemic side effects. To solve this issue, the postdoctoral researcher Jean-Michel Rabanel, under the supervison of Professor Charles…

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Anemic alternatives

'Bloodless' transfusion could solve global blood shortage

Blood transfusions save lives, yet the precious fluid is in desperately short supply around the globe. But what if transfusions don’t always require blood? A new mathematical model of the body’s interacting physiological and biochemical processes – including blood vessel expansion, blood thickening and flow-rate changes in response to the transfusion of red blood cells – shows that…

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Rare liver disease

New test improves diagnosis of autoimmune hepatitis

Autoimmune hepatitis (AIH) is a chronic liver inflammation that is triggered by an immunological malfunction. In this case, the immune system falsely recognises the patient's own liver cells as "foreign to the body". The symptoms of this rare liver disease are unspecific, and the exact cause is not yet known. If left untreated, AIH can lead to abnormal scarring (fibrosis) of the liver,…

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DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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Blood poisoning

Sepsis: 5-country survey shows lack of public awareness

On World Sepsis Day, in vitro diagnostics company bioMérieux and the UK Sepsis Trust reveal the results of a survey conducted in Europe regarding knowledge and attitudes towards sepsis. The findings demonstrate the need to accelerate awareness and education of the general population about this life-threatening condition.

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Stockholm3 test to reduce MRI

New blood test to improve prostate cancer screening

Researchers at Karolinska Institutet recently reported that magnetic resonance imaging (MRI) could reduce overdiagnoses and thereby improve prostate cancer screening. Now, the same research group has published a study in The Lancet Oncology, which shows that the addition of a novel blood test, the Stockholm3 test, can reduce the number of MRIs performed by a third while further preventing the…

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Search for signatures

‘Long Covid’ biomarkers in blood could lead to diagnostic test

Markers in our blood – ‘fingerprints’ of infection – could help identify individuals who have been infected by SARS-CoV-2, the coronavirus that causes Covid-19, several months after infection even if the individual had only mild symptoms or showed no symptoms at all, say Cambridge researchers. The team has received funding from the National Institute for Health Research to develop a test…

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Oncology early detection tool

Blood test for 50+ types of cancer promising for screening

Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…

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Sponsored • Product of the Month

For your most precious samples: MiniCollect® Capillary Blood Collection System

MiniCollect® offers a gentle way to collect small blood samples for a wide range of analyses. The capillary blood sample is becoming increasingly popular as specimen material due to its simpler and less invasive sampling procedure. One of the advantages is the low blood volume. Small quantities are sufficient to enable a variety of parameters to be tested.

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Covid-19 prevention side effects

Rare blood clots after Oxford-AstraZeneca vaccine: study sheds more light

A large study from Denmark and Norway published by The BMJ sheds more light on the risk of rare blood clots in adults receiving their first dose of the Oxford-AstraZeneca Covid-19 vaccine. The findings show slightly increased rates of vein blood clots including clots in the veins of the brain, compared with expected rates in the general population. However, the researchers stress that the risk of…

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After vaccination

Covid-19: Clinicians uncover rare blood clotting syndrome

A team led by a clinical academic at University College London (UCL) has outlined the mechanism behind rare cases of blood clots and low platelets seen in patients who have had the Oxford/AstraZeneca vaccine. The new study, published in the New England Journal of Medicine, highlights the importance of rapidly spotting this new syndrome, known as vaccine-induced thrombosis and thrombocytopenia…

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CVT risk evaluation

Thrombosis risk after Covid vaccination: actual infection far more dangerous, say experts

Researchers at the University of Oxford report that the risk of the rare blood clotting known as cerebral venous thrombosis (CVT) following Covid-19 infection is around 100 times greater than normal, several times higher than it is post-vaccination or following influenza. The study authors, led by Professor Paul Harrison and Dr Maxime Taquet from Oxford University’s Department of Psychiatry and…

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