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Prostate cancer

Prostate cancer (PCa) is not only one of the most common, but also one of the deadliest types of cancer in men. Diagnostics are correspondingly sophisticated, from imaging via ultrasound or MRI to various biopsy techniques – often even in combination. Keep reading for current developments in early detection, staging, therapy and research.

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Over-detection and biopsies

New procedures for prostate cancer screening

Organised screening enabling early detection and treatment of prostate cancer can reduce death by an impressive 20%, based on 16 years of findings of over 160,000 men participating in the landmark…

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The VISION clinical trial

A landmark for nuclear theranostics as prostate cancer treatment

For nuclear medicine specialists, 2021 may be heralded as a banner year validating the use of theranostic technology to treat cancer. Long-awaited results from an international phase 3 clinical trial…

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Cancer research

Blood tests predict prostate cancer resistance to chemotherapy drug

Regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel, according to research…

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Metastasis research

Tissue-engineered prostate tumours shed light on cancer spread

Research led by the Queensland University of Technology (QUT) on the interaction between prostate cancer cells and the tumour microenvironment has shed more light on the propensity of some types of…

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Treatment guidance

Metastatic prostate cancer comes in two forms

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment.

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AI

FDA authorizes software to identify prostate cancer

The FDA authorized marketing of software to assist medical professionals who examine body tissues in the detection of areas that are suspicious for cancer as an adjunct to the review of…

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Reducing collateral damage

A shield to protect patients during prostate cancer radiotherapy

Prostate cancer specialists from the Radiotherapy Department at Norfolk and Norwich University Hospitals Foundation Trust have become the first in the world to use an innovative technique to help patients receiving treatment for prostate cancer. Some patients receiving radiotherapy for prostate cancer will have their treatment split into two portions. The first stage of killing the cancerous…

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Stockholm3 test to reduce MRI

New blood test to improve prostate cancer screening

Researchers at Karolinska Institutet recently reported that magnetic resonance imaging (MRI) could reduce overdiagnoses and thereby improve prostate cancer screening. Now, the same research group has published a study in The Lancet Oncology, which shows that the addition of a novel blood test, the Stockholm3 test, can reduce the number of MRIs performed by a third while further preventing the…

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Oncology early detection tool

Blood test for 50+ types of cancer promising for screening

Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…

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Earlier, better insights

New developments in whole-body MRI for prostate cancer

Whole-body magnetic resonance imaging (WB-MRI) can detect prostate cancer and inform about treatment response and disease progression earlier and better than other imaging modalities. A Belgian expert will delve into the latest and future developments of the technique for prostate cancer and distant metastases imaging in a dedicated session at ECR. WB‐MRI and nuclear medicine -…

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Advancing diagnostic accuracy

PSMA PET/CT in prostate cancer evaluation

Hybrid PET/CT imaging can fully play to its strengths and steer treatment towards more effective procedures for diagnosing prostate cancer. The examination of the specific antigen PSMA with hybrid PET imaging enables treatment monitoring with significantly higher diagnostic accuracy than conventional imaging and therefore, Professor Clemens Cyran believes, will soon become the standard diagnostic…

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An unexpected and novel target

How our biological clock could save us from prostate cancer

Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It’s no wonder then that disrupting the clock can wreak havoc on our body. In fact, studies have shown that when circadian rhythms are disturbed through sleep deprivation, jet lag, or shift work, there is an increased incidence of some cancers including prostate cancer, which is the…

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RadClip

AI tool for MRI could transform prostate cancer surgery, treatment

Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have preliminarily validated an artificial intelligence (AI) tool to predict how likely the disease is to recur following surgical treatment for prostate cancer. The tool, called RadClip, uses AI algorithms to examine a variety of data, from MRI scans to molecular…

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AI-assisted MRI segmentation

Deep learning boost for prostate cancer workflow

Prostate cancer radiotherapy treatments guided by MRI are increasingly being explored to help improve patient outcomes and reduce toxicities after treatment. However, this development is being held back as the MRI approach is labour intensive and requires daily adaptive treatment planning, placing significant additional demands on clinician time and oncology services. To address this, a team of…

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List by top clinicians and researchers

Top 10 medical innovations for 2021

An up-and-coming gene therapy for blood disorders. A new class of medications for cystic fibrosis. Increased access to telemedicine. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of clinicians and researchers from Cleveland Clinic. In conjunction with the 2020 Medical Innovation Summit, Cleveland Clinic…

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Early detection

Prostate cancer risk: The role of relatives

If a father or brother has prostate cancer, his son or brother has an increased risk of this type of cancer. Whether this also applies when precancerous stages of this cancer are discovered in relatives has not yet been known. Now scientists have analyzed data from more than six million men to find out how high the risk of prostate cancer is in this case. Researchers at the German Cancer Research…

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Oncology

How cancer spreads in blood

A new study sheds light on proteins in particles called extracellular vesicles, which are released by tumor cells into the bloodstream and promote the spread of cancer. The findings suggest how a blood test involving these vesicles might be used to diagnose cancer in the future, avoiding the need for invasive surgical biopsies.

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Better diagnosis, better treatment

Prostate cancer deaths to decline (almost) everywhere in the EU

Death rates from prostate cancer are predicted to fall in 2020 in the EU, largely due to better diagnosis and treatment, according to new research published in the leading cancer journal Annals of Oncology. In the latest predictions for cancer deaths in the EU for 2020, researchers led by Carlo La Vecchia (MD), Professor at the School of Medicine, University of Milan (Italy), show that since 2015…

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Prostate Urine Risk (PUR)

Urine test could reduce unnecessary prostate cancer biopsies

Unnecessary prostate cancer biopsies could be reduced by 60 per cent thanks to new research from the University of East Anglia (UEA). Researchers have developed new methods to identify biomarkers for prostate cancer by combining information from multiple parts of urine samples. It is hoped that the breakthrough could help large numbers of men avoid an unnecessary initial biopsy.

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Next generation diagnostics

Using AI to detect and grade prostate cancer

Researchers at Karolinska Institutet have developed a method based on artificial intelligence for histopathological diagnosis and grading of prostate cancer. The AI-system has the potential to solve one of the bottlenecks in today’s prostate cancer histopathology by providing more accurate diagnosis and better treatment decisions. The study, presented in The Lancet Oncology, shows that the…

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