Prostate cancer

Prostate cancer (PCa) is not only one of the most common, but also one of the deadliest types of cancer in men. Diagnostics are correspondingly sophisticated, from imaging via ultrasound or MRI to various biopsy techniques – often even in combination. Keep reading for current developments in early detection, staging, therapy and research.

News • Urine-based diagnostics

New prostate cancer test to help avoid unnecessary biopsies

US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.

News • Nuclear medicine

Prostate cancer: New SPECT/CT technique for greater treatment precision

A new SPECT/CT imaging technique using lead-212 (²¹²Pb) shows promise in targeted alpha therapy (TAT) for patients with metastatic castration-resistant prostate cancer.

News • Biparametric scan

Prostate cancer screening: two-part MRI is enough, study shows

A three-part ‘multiparametric’ MRI of the prostate is standard of care in the UK for patients suspected of having prostate cancer. Now, a study shows two-part scans are sufficient for diagnosis.

Article • Prostate cancer treatment

MR-guided radiotherapy: a potential game changer

Prostate radiotherapy techniques have been transformed over the past two decades. One promisting technique in this context is magnetic resonance-guided radiotherapy. The latest clinical results show…

News • Preventive blood test

Prostate cancer screening: Study advocates 5-year-interval

How often should men get checked for their level of PSA, a marker for prostate cancer? A German study involving over 12,500 men shows that a five-year interval between tests is safe.

News • Accurate detection and removal

Radioguided surgery to treat metastatic lymph nodes in prostate cancer

Dutch researchers use PSMA targeting to improve detection of prostate cancer, improving nodal staging and guiding more accurate surgery for this important patient population.

News • Revealed by AI

Prostate cancer: more than just one disease

Artificial Intelligence has helped scientists reveal a new form of aggressive prostate cancer which could revolutionise how the disease is diagnosed and treated in the future.

News • Restoring responsiveness

New method could crack treatment-resistant prostate cancer

Targeting a specific protein, Finnish researchers may have found a way to restore drug-resistant neuroendocrine prostate cancer to a state that responds to treatment.

News • CTC, ctDNA and exosomes in PCa management

Prostate cancer: Blood-based liquid biopsies yield valuable information

US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.

News • SCN tumor development

How prostate cancer grows aggressive to evade treatment

In a new study, UCLA researchers demonstrated how small cell neuroendocrine prostate cancer tumor cells can arise from less aggressive prostate tumors.

News • Nuclear medicine

Prostate cancer: staging issues in bone scans compared with PSMA PET

Bone scans have been found to overstage prostate cancer at initial staging compared to prostate specific membrane antigen (PSMA) PET, according to new research.

News • AI-based imaging and reporting solutions for MRI

Philips partners with imaging biomarker specialist Quibim

Philips and Quibim have signed a multi-year agreement to work on an integrated solution including an AI-based software to automate real-time prostate gland segmentation in MR images.

News • Surge in under 50s in past decades

The rising tide of early-onset cancers

Cancer has become strikingly more common in people under 50 in the past three decades, an international research team finds. The reseachers explore what this means for future death tolls.

News • Imaging for targeted biopsy

MRI and ultrasound "fusion" improves prostate cancer detection

Combining ultrasound and MRI technology can help detect prostate cancer at an earlier stage and potentially save lives, according to new University of Dundee research.

News • Prostate cancer detection

Personalized PSA screening may improve accuracy

The accuracy of prostate-specific antigen (PSA) screening can be improved by including genetic factors that cause changes in PSA levels not associated with cancer, according to a multi-center study.

News • Perilous PSA policy

Prostate cancer ‘test by request’ drives overdiagnosis, argue experts

Experts argue that shared decision policies between patients and their doctors have led to high rates of PSA testing and clear medical harm, with minimal benefit and inequity.

News • Oncology & Cancer

Research uncovers alternate mechanism for producing key protein in metastatic prostate cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

News • Radiotherapy trial

Prostate cancer: radical approach greatly reduces treatment visits

A new clinical trial has shown that men diagnosed with prostate cancer can benefit from ‘radical radiotherapy’ that delivers treatment in five hospital visits instead of the typical 20.

News • PSMA-PET/CT

Advanced imaging may help in clinical treatment of prostate cancer

An advanced imaging method is showing promise as a way to improve the diagnosis of prostate cancer by giving clinicians a clearer view of suspected tumours during biopsy.

News • Augmented reality system

AR-powered free-hand, real-time needle guidance for prostate cancer diagnosis

Researchers demonstrate a HoloLens AR system that enables accurate, flexible needle guidance for transperineal prostate interventions such as biopsy, focal laser ablation, and brachytherapy

News • Rapid screening diagnostic

94% accuracy: new prostate cancer blood test beats PSA method

Researchers have developed a new blood test to detect prostate cancer which displays greater accuracy than the current prostate-specific antigen (PSA) method.

News • Nuclear medicine

Prostate cancer: PSMA PET/MRI accurately predicts recurrence risk

In men recently diagnosed with intermediate or high-grade prostate cancer, PSMA PET/MRI can successfully determine whether their cancer is likely to return within two years of a prostatectomy.

News • Stereotactic body radiotherapy

Advanced radiotherapy speeds up prostate cancer treatment

An advanced radiotherapy technique can be used to safely treat prostate cancer patients in as little as one to two weeks, compared with the current standard, which takes one to two months.

News • Equivalent outcomes in 5 vs 8-week treatment

High-risk prostate cancer: Study confirms effectiveness of shortened radiation therapy

A new randomized study confirms that men with high-risk prostate cancer can be treated with a moderately shortened course (5 vs. 8 weeks) of radiation therapy.

News • Focal therapy study

New prostate cancer treatment to reduce risk of impotence

Focal treatment of prostate cancer involves treating only the tumor and not the entire gland, sparing surrounding tissue and nerves. The method is being evaluated in a research study.

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