Treatment

Medical innovations are rapidly expanding therapy options for many diseases. Keep reading to find more information on new therapies, surgical techniques, effective medication and patient care.

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HER2-targeted therapy

Promising results for therapy of non-small cell lung cancer

New data highlights a promising new treatment for individuals with HER2-mutant non-small cell lung cancer (NSCLC).

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First-of-its-kind study

Computer-assisted colonoscopies reduces rate of missed lesions

Decreasing the rate of missed lesions could translate into fewer cases of colon cancer.

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Combined with antibiotics

Bacteria-killing viruses to fight antibiotic-resistant bacteria

Researchers have found a way to defeat the multi-resistant bacterium Mycobacterium abscessus, a relative of the causes of tuberculosis and leprosy.

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Orthopedy

Antimicrobial coating for implants prevents infections

Customizable to individual patients and requiring less than 10 minutes to prepare and use, new surgical implant coating prevented 100% of infections in mice.

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Blood poisoning

Sepsis: 5-country survey shows lack of public awareness

On World Sepsis Day, in vitro diagnostics company bioMérieux and the UK Sepsis Trust reveal the results of a survey conducted in Europe regarding knowledge and attitudes towards sepsis. The findings…

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Precision oncology

Personalized health and genomics: Minimizing collateral damage

A solid diagnosis has always been the first step on any patient’s journey to health. However, diagnostic categories are necessarily oversimplifications. In the last decades, medical professionals and scientists have begun to uncover the true variability in patients’ physiological and biochemical make-up that is the principal cause for individual variations in the way diseases present themselves. A number of technologies have contributed to this massive increase in data and knowledge. In particular, radiology, histopathology and genetic sequencing are key fields in personalized medicine, and precision oncology is one of their top applications.

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Treatment guidance

Metastatic prostate cancer comes in two forms

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment.

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High risk patients

WHO recommends antibody treatment for Covid-19 patients

A treatment combining two antibodies is recommended for two specific groups of patients with Covid-19 by a WHO Guideline Development Group panel of international experts and patients.

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Eye health

FDA Approves biosimilar to treat macular degeneration disease

The FDA approved Byooviz (ranibizumab-nuna) as the first biosimilar to Lucentis (ranibizumab injection) for the treatment of several eye diseases and conditions.

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Orthopaedic advances

Virtual training by hip implant simulator

Trainee trauma or orthopaedic surgeons have limited chances to practice hip replacement surgery before their first hands-on case. To change this, a team in the Dynamic HIPS project aim to improve this by creating a dynamic hip replacement simulator for future surgeons to practice the intervention and develop a reality-based feel for the procedure.

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DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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Classifying subtypes

Breast cancer ‘ecotypes’ could lead to more personalised treatment

A team led by the Garvan Institute of Medical Research has revealed a new approach for classifying breast cancer subtypes based on their cell profile, which could help personalise treatments for patients. By analysing breast cancer biopsies from patients at Sydney hospitals, the researchers revealed more than 50 distinct cancer, immune and connective cell types and states, which could assign…

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Combined chemotherapy

Pancreatic cancer: New treatment promising for older patients

Pancreatic cancer is a disease of the elderly: the average age of patients is 72. In Austria, about 1,600 people are diagnosed each year. Since pancreatic cancer has no specific symptoms, it is not usually diagnosed until the tumor is locally advanced or has already metastasized. Once the tumor has metastasized, it is usually no longer treatable by surgery or radiotherapy. In addition, the drug…

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Eye disease prevention

Using AI to screen for glaucoma

Scientists from the Nanyang Techniogical University (NTU) Singapore, in collaboration with clinicians at Tan Tock Seng Hospital (TTSH) in Singapore, have developed a novel method that uses artificial intelligence (AI) to screen for glaucoma, a group of eye diseases that can cause vision loss and blindness through damage to the optic nerve at the back of the eye. Glaucoma is often called ‘the…

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Coronavirus prevention

Double vaccination cuts risk of Long Covid in half

Adults who have received a double vaccination are 49% less likely to have Long Covid should they contract a Covid-19 infection, according to new research from King's College London. The scientists analysed data from participants logging their symptoms, tests and vaccines on the UK ZOE COVID Symptom Study app between 8th December 2020 and 4 July 2021, including 1,240,009 (first dose) and 971,504…

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Titanium-alloy knee plates

3D printing simplifies high tibial osteotomy

3D metal printing technology is producing personalised medical-grade titanium-alloy plates that perfectly fit individuals suffering arthritis of the knee. Engineers at the University of Bath’s Centre for Therapeutic Innovation (CTI) working with 3D Metal Printing Ltd, are using the TOKA (Tailored Osteotomy for Knee Alignment) treatment to improve the surgical procedure and fit of high-tibial…

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Medication combination

'4-in-1' blood pressure pill shows great promise

The first large-scale, long-term trial of a new strategy using combinations of very low-doses in one capsule, has demonstrated significantly improved control of high blood pressure - the leading cause of heart attack and stroke. This first large-scale, randomised controlled clinical trial of starting this novel combination blood pressure medication brought blood pressure under control in 80…

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Cardiology advances

Digital solutions for heart failure patients

Triage HF Plus, highlighted in the BCS conference session ‘Digital Innovation in Cardiology - What's new?’ is a digital heart failure care project that uses a customised algorithm to detect early signs of deterioration in patients with implanted devices. During her presentation ‘Digital solutions to identify worsening heart failure’, consultant cardiologist Dr Fozia Ahmed discussed the…

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Molecular targeting for better results

Emerging novel tracers for cardiovascular imaging

Molecular imaging, guided by novel tracers, is emerging as an important diagnostic and therapeutic tool in cardiovascular medicine. Delegates at ICNC-CT, the online International Conference on Nuclear Cardiology and Cardiac CT, also heard that cardiology can learn from fields such as oncology and neurology that have already made important advances in this area. Professor Frank Bengel, who is…

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Transcatheter aortic valve implants

TAVI: from short-term effects to lifetime management

Until recently, TAVI, the minimally invasive procedure in which a replacement valve is inserted inside a diseased valve has been mostly prescribed for patients too weak to face open heart surgery – largely involving those in the 80-plus age group. Today, due to greater longevity plus advancing skills that result in risks reduction, TAVI is increasingly prescribed for patients in their 70s and…

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Reducing collateral damage

A shield to protect patients during prostate cancer radiotherapy

Prostate cancer specialists from the Radiotherapy Department at Norfolk and Norwich University Hospitals Foundation Trust have become the first in the world to use an innovative technique to help patients receiving treatment for prostate cancer. Some patients receiving radiotherapy for prostate cancer will have their treatment split into two portions. The first stage of killing the cancerous…

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Heart-related hospitalisations

Drug danger: opioid use linked to steep rise in cardiac arrests

A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. The research is presented at ESC Congress 2021. Opioid use disorder, which includes dependence and addiction, affects more than two million people in the US, while opioid overdose is the leading cause of death for those aged 25 to…

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Hybrid care models

Telemedicine or in-person care: Why not both?

Will telehealth replace traditional in-person healthcare? Healthcare and digital health professionals around the world have moved beyond this question. Telehealth scenarios are here to stay, and so is traditional healthcare. The relevant question is how both can be combined for optimum results. This is the focus of hybrid care models. Jonah Comstock of HIMSS recently presented a webinar on…

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Surgical image and video management

OR becoming an integrated high-performance hub

Operating rooms are extremely complex, and the level of complexity is steadily increasing. This is reflected in the growing number of medical devices, on the one hand, and in the continuously increasing volume of data, on the other. Nowadays, surgical staff are confronted with a flood of highly specialised technology. The challenge is to create workplaces that are as uniform as possible and…

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Telehealth

Sheba Beyond: Creating Israel’s first virtual hospital

Israel’s first virtual hospital has been created following the advances and applications learned from using telemedicine tools and techniques to care for coronavirus patients in isolation wards. Sheba Beyond was established in January and over the last few months has successfully delivered care to patients across a range of areas. The development of the project was outlined to the DMEA –…

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Controlling KRAS

New targeted gene therapy could stop lung cancer progression

A newly targeted therapy could help millions of lung cancer patients worldwide keep their cancers from spreading, says an expert at Cleveland Clinic, on the occasion of World Lung Cancer Day. Dr. Khaled Hassan, of the Hematology and Medical Oncology Department at Cleveland Clinic, said: “The KRAS mutation is a main gene that drives cancer, and lung cancer specifically, but previously it’s…

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Orthopaedics

Iliac crest reconstruction: 15 patients recruited into GreenBRIC study

GreenBone Ortho, a company specialising in bone regeneration, announces that it has achieved its aim of recruiting 15 patients into the GreenBRIC study. GreenBRIC study is a prospective, open label, single-arm, First-in-Human clinical investigation, in male and female patients, aged between 18 and 70 years, undergoing surgery to correct bone defects using GreenBone Implant, specifically for iliac…

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Automated whole-body reperfusion

New technique to increase survival after cardiac arrest

Researchers at the Medical Faculty of the University of Freiburg have developed an improved therapeutic approach to resuscitate people after cardiac arrest - often without neurological complications. Around 50,000 people suffer sudden cardiac arrest in Germany every year. When occurring outside a hospital, the chances of survival are only ten percent. Survivors often suffer from severe permanent…

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Cancer care

Remote 24-hour monitoring shows promise in chemotherapy patients

Remote 24-hour monitoring for cancer patients receiving chemotherapy helps to better manage side effects and improve quality of life, finds a study published by The BMJ. The researchers say remote monitoring can provide a safe, secure, and “real time” system that optimises symptom management and supports patients to remain at home - and is particularly relevant in the context of the Covid-19…

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