Tick-borne infection

New techniques detects Lyme disease weeks before current tests

Researchers have developed techniques to detect Lyme disease bacteria weeks sooner than current tests, allowing patients to start treatment earlier. The new techniques can detect an active infection…

Cancer

Drug-resistant renal cell carcinoma: Nanotherapy offers hope

A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a…

Neurology

New potential biotherapy against Alzheimer's disease

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease. The study reveals that soluble…

Fertilisation

IVF: Why a single embryo sometimes leads to twins or triplets

It has been known for some time that it is better to transfer a single embryo to a woman’s womb during assisted reproduction treatment (ART) rather than several embryos in order to avoid a multiple pregnancy and the risks associated with it such as foetal deaths, miscarriage, premature delivery and low birthweight. However, even when single embryo transfer (SET) is performed, some women still become pregnant with twins or even triplets. In a study published in Human Reproduction, one of the world’s leading reproductive medicine journals, researchers have investigated one of the reasons why this happens and have, for the first time, been able to calculate that the proportion of multiple pregnancies after SET is 1.6% and that 1.36% of multiple pregnancies after SET occur as a result of…

Immunotherapy

Toward an “ultra-personalized” therapy for melanoma

With new immunotherapy treatments for melanoma, recovery rates have risen dramatically – in some cases to around 50%. But they could be much higher. A new study led by researchers at the Weizmann…

Therapy

Could these special antibodies lead to HIV vaccine?

Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV.…

Debilitating disease

Discovery of a new anti-epileptic drug target

An international collaboration between Imperial College London, Singapore's Duke-NUS Medical School and Belgium-based pharmaceutical company UCB led to the discovery of a new anti-epileptic drug…

New study

Rethinking the six-hour rule for stroke victims

Neurologist who coined the phrase "Time is Brain" says message is not so simple anymore. Rather there should be no hard-and-fast rule governing when therapy can be given because strokes…

Prostate cancer

Magnetic surgery takes promising first steps

Magnets may play a central role in the future of surgery. This summer, US surgeon Dr. Jeffrey Cadeddu performed the first of several magnet-assisted prostate cancer surgeries he has now done.…

Brain tumors

Researchers find missing immune cells that could fight glioblastoma

Glioblastoma brain tumors can have an unusual effect on the body's immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body's defenses. Where the…

Pulmonary Alveolar Proteinosis

Taking a pill can effectively treat brutal lung disease

Researchers Cincinnati Children's Hospital Medical Center report that they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary…

Tech from Taiwan

Augmented reality is the future of surgery

Physicians have been performing surgery with the assistance of x-ray technology for almost half a century. While this technology has been progressing steadily, its limitations continue to be a major…

Gastroenterology

High-fat diet can cause pancreatic cancer – but there's hope

A high-fat diet may promote the growth of pancreatic cancer independent of obesity because of the interaction between dietary fat and cholecystokinin (CCK), a digestive hormone. In addition, blocking…

Insight without Incision

Epilepsy surgery improves thanks to advances in noninvasive brain imaging

About a third of epilepsy sufferers require treatment through surgery. To check for severe epilepsy, clinicians use a surgical procedure called electrocorticography (ECoG). An ECoG maps a section of…

New report

How to get Europe's digestive health back in shape

Obesity, cancers and other gastrointestinal diseases have digestive systems all over Europe in a chokehold. In a new report, non-profit organisation United European Gastroenterology (UEG) sheds a…

bioengineering

Advancing technique for of personalied bone grafts

Scientists have developed a new bone engineering technique called Segmental Additive Tissue Engineering (SATE). The technique allows researchers to combine segments of bone engineered from stem cells…

BIA-ALCL

Breast implant cancer risks: are women aware?

Breast surgeons across the UK must ensure women are aware of BIA-ALCL, a non-Hodgkin’s lymphoma that is associated with implants; and more responsibility must be taken to diagnose and report cases,…

31st Annual Cardiologists Conference

Every heart beat counts

The term “Cardiology” means the division of science that converses functions, diseases and health activities related to heart. It is also connected with blood, arteries and veins, as blood is the…

Radiation protection

Using skin creams during radiation therapy: Is it safe?

Nearly two-thirds of all cancer patients in the United States will undergo radiation therapy as part of their treatment, and as many as 90 percent of those patients will experience radiation…

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Tumor research

microRNAs predict recurrence risk of head and neck cancer

A new method predicts the course of HPV-negative head and neck cancer after radiation chemotherapy. According to a recent article in the journal ‘Clinical Cancer Research’, five microRNAs (miRNAs) can provide the decisive data. The work was conducted at the Helmholtz Zentrum München and the University Hospital of the Ludwig-Maximilians-Universität München (LMU) in close collaboration with…

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Remote monitoring

It’s time to look again at IN-TIME

As the world’s largest cardiology congress gets underway in Munich, it’s worth looking back to previous ESC sessions to see how scientific debates have evolved. At ESC 2016, held in Rome, REM-HF investigators presented data suggesting remote monitoring in implantable cardiac devices offered no added clinical benefit. Two years on, there are new reasons to re-examine that conclusion, with a…

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Heard at the British Cardiovascular Society conference

The role of nanomedicine in CV diagnosis

Nanomedicine will play an increasingly important role in future diagnosis and treatment of cardiovascular disease, a subject explored in detail by four expert speakers at the British Cardiovascular Society conference in Manchester in June. The conference heard that the technology – dealing with dimensions and tolerances of less than 100 nanometres, especially the manipulation of individual…

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After a stroke

‘Hole in the heart’: Experts recommend catheter based closure

A catheter based procedure to close a type of ‘hole in the heart’ followed by antiplatelet drugs (e.g. aspirin) should be recommended for patients under 60 years old, who have also had a stroke, say a panel of experts in The BMJ today. The procedure involves slowly moving a catheter into the heart to close the hole. Most guidelines currently advise against the closure procedure and instead…

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Acute myeloid leukaemia

Researchers draw AML ‘family trees’ in patients treated with enasidenib

For the first time, a team of international researchers have mapped the family trees of cancer cells in acute myeloid leukaemia (AML) to understand how this blood cancer responds to a new drug, enasidenib. The work also explains what happens when a patient stops responding to the treatment, providing important clues about how to combine enasidenib with other anti-cancer drugs to produce…

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Brain cancer

Typical mutation in cancer cells stifles immune response

The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune system. It thus blocks the body’s immune response in the battle against the mutant molecule and also impedes immunotherapy against brain cancer. This finding opens new insights into cancer development and progression and it also suggests that rethinking antitumor…

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Dupuytren's disease

New hope for patients with incurable, disabling hand condition

Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for progression of Dupuytren's disease.

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Neurology

A new therapy for common cause of dementia?

Scientists have uncovered a potential approach to treat one of the commonest causes of dementia and stroke in older people. Studies with rats found the treatment can reverse changes in blood vessels in the brain associated with the condition, called cerebral small vessel disease.

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Epidemics

Animal health drug could stop outbreaks of malaria and Zika virus

Medicines given to household pets to kill fleas and ticks might be effective for preventing outbreaks of malaria, Zika fever and other dangerous insect-borne diseases that infect millions of people worldwide, according to a new study led by scientists at Calibr, a non-profit drug discovery institute closely affiliated with Scripps Research and TropIQ Health Sciences, a Dutch social enterprise.

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Health IT

Computer algorithm maps cancer resistance to drugs

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center. The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance.

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Plaster

Self-adhesive drug-eluting patch to treat oralulcers

Until now ulcers inside the mouth have been treated using creams or mouthwashes for the whole mouth. A new biodegradable patch administers steroids directly to oral ulcers and forms a protective barrier. Scientists from the University of Sheffield’s School of Clinical Dentistry, working in close collaboration with Dermtreat A/S from Copenhagen, have developed a unique patch using special…

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Patient safety

Greiner Bio-One expands blood collection product range

The Vacuette Safety Winged Set is a new addition to Greiner Bio-One’s (GBO) range of safety products. GBO now offers its customers an even wider selection of safety blood collection sets. In response to high demand for Greiner Bio-One safety products, the existing range will be joined by the new Vacuette Safety Winged Set. As always, the aim is to provide functional, user-friendly and…

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Oncology

Breaking through a tumor's defenses

Babraham Institute researchers have shown that some tumours use not one but two levels of protection against the immune system. Knocking out one level boosted the protective effects of the second and vice versa. The research demonstrates that a two-pronged approach targeting both cell types simultaneously may offer a promising route for the development of new cancer immunotherapies.

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Breast cancer patients

Study confirms: Scalp Cooler prevents alopecia

‘Scalp cooling successfully prevents alopecia in breast cancer patients undergoing anthracycline or taxane-based chemotherapy’, according to the latest clinical data published in The Breast. The paper, written by clinicians from the Berlin Oncology Center, Germany, revealed that 71% of women who took part on the study retained their hair as a result of using the Paxman Scalp Cooler. Scalp…

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Surgical implant for damaged eyes

FDA approves first artificial iris

The U.S. Food and Drug Administration approved the first stand-alone prosthetic iris in the United States, a surgically implanted device to treat adults and children whose iris is completely missing or damaged due to a congenital condition called aniridia or other damage to the eye. The iris is made of thin, foldable medical-grade silicone and is custom-sized and colored for each individual…

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New study

Pancreatic cancer: Chemotherapy goes platinum

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations. The same study also found that those with BRCA1 or BRCA2 had better survival rates with platinum-based chemotherapy, compared with similar patients…

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Bone health

Osteoporosis defined: causes, symptoms and treatments

Weak, easily broken bones are an epidemic in the United States. They’re often tied to osteoporosis, a disease that causes bones to degenerate over time. This makes them less flexible, more brittle, and easier to break. According to the International Osteoporosis Foundation, more than 44 million Americans aged 50 and older either have or face the threat of developing osteoporosis due to low bone…

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Tropical diseases

Investigating schistosomiasis

Schistosomiasis, a disease that is common in sub-Saharan Africa, is particularly widespread in Madagascar. The Schistosoma mansoni parasite responsible for the disease is linked to fibrotic changes in the liver which can be detected using point-of-care ultrasound. Junior doctor Hannah Russell described how point-of-care ultrasound was put to the test in remote locations during an expedition to…

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