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Brain

More than 80 billion neurons, trillions of synapses and almost 6 kilometres of neural pathways: The brain is an anatomical masterpiece; it is our control centre, memory store, coordinator of thoughts and movement – and still puzzles science. In medicine, the focus is on neurodegenerative diseases such as Alzheimer's and Parkinson's, but also on cerebrovascular disorders such as strokes and brain tumours, notably glioblastoma.

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News • Researchers explore role of lymphoid structures

‘Immune organ’ inside skull could help fight brain cancer

Researchers have found an ‘immune organ’ inside the skull, which directs brain defenses. The findings may offer a new way to fight brain cancer and neurodegenerative diseases.

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News • Neuroscience

Possible biomarker for suicidal thoughts identified

Researchers identified a possible biomarker linked to severe suicidal thoughts. It may also help explain why some people recover, opening a new path for research into resilience and prevention.

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News • Polygenic risk assessment

Sleep study for early detection of Alzheimer's risk

New research suggests that subtle markers during sleep – such as nocturnal micro-awakenings – may yield early clues to a greater genetic risk of developing Alzheimer’s disease.

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News • Neuroimaging

Alzheimer’s: MRI metric identifies early white matter damage

A diffusion MRI metric can detect changes in white matter tracts not visible on conventional MRI – this could help identify early abnormalities in the brain associated with Alzheimer’s disease.

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News • Molecular psychiatry

Late-onset psychosis: PET scans reveal tau buildup in the brain

The cause of hallucinations and delusions that start in midlife or later is often unclear. In a new study, PET/MR scans reveal that these symptoms may be linked to brain changes also seen in dementia.

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News • Cardiovascular and cognitive changes

MASLD: Exploring the systemic impact of fatty liver disease

A new study links metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) to an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications.

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