More than 80 billion neurons, trillions of synapses and almost 6 kilometres of neural pathways: The brain is an anatomical masterpiece; it is our control centre, memory store, coordinator of thoughts and movement – and still puzzles science. In medicine, the focus is on neurodegenerative diseases such as Alzheimer's and Parkinson's, but also on cerebrovascular disorders such as strokes and brain tumours, notably glioblastoma.
Researchers identified a possible biomarker linked to severe suicidal thoughts. It may also help explain why some people recover, opening a new path for research into resilience and prevention.
New research suggests that subtle markers during sleep – such as nocturnal micro-awakenings – may yield early clues to a greater genetic risk of developing Alzheimer’s disease.
A diffusion MRI metric can detect changes in white matter tracts not visible on conventional MRI – this could help identify early abnormalities in the brain associated with Alzheimer’s disease.
The cause of hallucinations and delusions that start in midlife or later is often unclear. In a new study, PET/MR scans reveal that these symptoms may be linked to brain changes also seen in dementia.
A new study links metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) to an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications.
A research team has developed a new method that directly optimizes the thickness of a 3D-printed lens to simultaneously and precisely stimulate multiple regions of the brain.
Using a two-step AI approach, researchers have developed a computationally efficient new method to detect and classify brain tumors from MRI scans more accurately.
Low brain metabolism as measured from 18F-FDG PET/CT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research.
What happens in the brain during anaesthesia? A novel brainwave monitoring method could help lower the risk of intraoperative awareness, postoperative delirium, and long-term cognitive decline.
In a study, researchers found unusually high levels of urea in the brains of people with frontotemporal dementia and ALS. The findings raise questions about how the brain clears harmful substances.
Virus-associated molecules in the foot are enough to trigger the network: Research reveals a remarkable mechanism, in which the brain prepares for a potential viral attack within hours of infection.
Researchers have developed an AI technology that analyzes daily activity and environmental data from older adults to identify digital behavioral markers of cerebrovascular disease risk at home.
A simple bedside eye test may help predict recovery of consciousness in patients with severe brain injuries, according to new research.
A new experimental compound, called OLE, helps the brain enclose and contain beta-amyloid plaques – a hallmark of Alzheimer’s disease –, reducing their size and toxicity.
Adapting blood pressure targets after thrombectomy for acute ischemic stroke significantly improves patients’ functional recovery without increasing the risk of complications, a new study finds.
A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.
A promising technology enables deep brain stimulation without the need to surgically implant electrodes. This could pave the way for its use in the treatment of neurological and psychiatric disorders.
At which point does Alzheimer’s disease pathology lead to dementia? Researchers identified distinct mechanisms in the brain, which could represent an important target for future therapies.
A new PET imaging approach that measures synaptic density in the spinal cord provides a quantitative way to assess the brain's functional wiring in patients with multiple sclerosis.
