More than 80 billion neurons, trillions of synapses and almost 6 kilometres of neural pathways: The brain is an anatomical masterpiece; it is our control centre, memory store, coordinator of thoughts and movement – and still puzzles science. In medicine, the focus is on neurodegenerative diseases such as Alzheimer's and Parkinson's, but also on cerebrovascular disorders such as strokes and brain tumours, notably glioblastoma.
In a study, researchers found unusually high levels of urea in the brains of people with frontotemporal dementia and ALS. The findings raise questions about how the brain clears harmful substances.
Virus-associated molecules in the foot are enough to trigger the network: Research reveals a remarkable mechanism, in which the brain prepares for a potential viral attack within hours of infection.
Researchers have developed an AI technology that analyzes daily activity and environmental data from older adults to identify digital behavioral markers of cerebrovascular disease risk at home.
A simple bedside eye test may help predict recovery of consciousness in patients with severe brain injuries, according to new research.
A new experimental compound, called OLE, helps the brain enclose and contain beta-amyloid plaques – a hallmark of Alzheimer’s disease –, reducing their size and toxicity.
Adapting blood pressure targets after thrombectomy for acute ischemic stroke significantly improves patients’ functional recovery without increasing the risk of complications, a new study finds.
A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.
A promising technology enables deep brain stimulation without the need to surgically implant electrodes. This could pave the way for its use in the treatment of neurological and psychiatric disorders.
At which point does Alzheimer’s disease pathology lead to dementia? Researchers identified distinct mechanisms in the brain, which could represent an important target for future therapies.
A new PET imaging approach that measures synaptic density in the spinal cord provides a quantitative way to assess the brain's functional wiring in patients with multiple sclerosis.
A new AI-based method can reduce the time required for certain MRI brain scans by up to 90% while maintaining a high level of accuracy, paving the way for more efficient and accessible neuroimaging.
Persistent long Covid symptoms are often linked to brain inflammation. However, results from a new study point at a different explanantion for fatigue, cognitive impairment, anxiety, and depression.
New research has found that a genetic factor best known for increasing the risk of Alzheimer's disease, may also influence how pathological changes spread in amyotrophic lateral sclerosis (ALS).
New research reveals that testosterone slows glioblastoma growth—the opposite of the androgen’s effect on tumors outside the brain.
Researchers at the Leibniz Institute on Aging have shown that oxidative stress impairs protein quality control in the brain – and that this process is reversible.
Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.
Why do some older adults remain mentally sharp despite having Alzheimer's? Decoding this natural resilience could pave the way for earlier detection and new strategies to prevent memory loss.
A 3D brain marker may help identify which patients with idiopathic normal pressure hydrocephalus (iNPH) benefit from shunt surgery – improving outcomes and sparing others from ineffective treatment.
Repeated menstrual cycles may do more than trigger endometriosis – they may rewire the brain, a new study finds. Recurring inflammation can sensitize the nervous system, driving lasting pain.
