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Brain

More than 80 billion neurons, trillions of synapses and almost 6 kilometres of neural pathways: The brain is an anatomical masterpiece; it is our control centre, memory store, coordinator of thoughts and movement – and still puzzles science. In medicine, the focus is on neurodegenerative diseases such as Alzheimer's and Parkinson's, but also on cerebrovascular disorders such as strokes and brain tumours, notably glioblastoma.

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News • OLE-induced microglia rewiring

Molecule “reprograms” the brain’s defenses against Alzheimer’s disease

A new experimental compound, called OLE, helps the brain enclose and contain beta-amyloid plaques – a hallmark of Alzheimer’s disease –, reducing their size and toxicity.

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News • Personalized blood pressure targets

Toward a paradigm shift in post-stroke management

Adapting blood pressure targets after thrombectomy for acute ischemic stroke significantly improves patients’ functional recovery without increasing the risk of complications, a new study finds.

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News • Neurology

New high resolution PET scanner reveals early signs of brain diseases

A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.

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News • Temporal interference stimulation

Towards deep brain stimulation without surgery

A promising technology enables deep brain stimulation without the need to surgically implant electrodes. This could pave the way for its use in the treatment of neurological and psychiatric disorders.

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News • Key biological mechanisms identified

Finding the “tipping point” of Alzheimer's

At which point does Alzheimer’s disease pathology lead to dementia? Researchers identified distinct mechanisms in the brain, which could represent an important target for future therapies.

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News • New MS monitoring approach

PET imaging reveals synaptic loss in multiple sclerosis

A new PET imaging approach that measures synaptic density in the spinal cord provides a quantitative way to assess the brain's functional wiring in patients with multiple sclerosis.

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