Gastrointestinal tract

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News • Swallowable nanoscale delivery platform

Gastric cancer: nanocages could bring targeted treatment in a pill

A swallowable "nanocage" may offer a new strategy for treating gastric cancer more precisely while reducing damage to healthy tissue, according to findings from a new preclinical study.

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News • Commensal dysbiosis

Study links bile acid buildup to breast cancer metastasis

A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new research reveals. The findings could open the door to new ways to prevent cancer metastasis.

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News • Early detection biomarker

Using gut bacteria to predict diabetes risk

The presence of certain bacteria in the gut microbiota, and fluctuations in a person’s metabolism, have been identified as potential biomarkers for type 2 diabetes years before its onset.

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News • Body composition radiodensity

New CT-based marker to refine gastric cancer prognosis

Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.

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News • Additive manufacturing

3D printed 'lily stent' could speed recovery after weight-loss surgery

To treat gastric leaks after weight loss surgery, doctors usually rely on a device not suited for the task. This may result in further complications. A redesigned stent could help fix this issue.

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News • Hooked to help

Bioengineered hookworms could serve as drug factories inside the gut

A hookworm can survive in the human gut for years. Researchers have now harnessed that biological mechanism, engineering a hookworm to produce and deliver a drug within a living host.

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Article • Reshaping GI cancer care

Pathologists at the heart of precision oncology

Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…

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