Gastrointestinal tract

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News • Microbial interactions

Gut bacteria interactions show promise as health and disease marker

To better distinguish between healthy and diseased gut microbiomes, scientists have created an index that tracks microbial behavior and signals conditions such as colorectal cancer.

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News • Gastric multi-regional assembloid

Lab-grown mini-stomachs to boost understanding of rare diseases

A new type of lab-grown organoid that mimics the behaviour of a human stomach could boost the understanding of rare gastric diseases, researchers say.

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News • Systemic mechanism discovered

Chemotherapy rewires gut bacteria to curb metastasis

Chemotherapy does more than kill cancer cells: It reshapes the gut microbiome, making the body less permissive to metastasis. This finding opens new avenues for adjuvant strategies.

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News • When good bacteria fight back

Klebsiella strain to protect against IBD gut infections

New research shows that a harmless strain of Klebsiella – discovered by chance in laboratory experiments – can eliminate infections and reduce gut inflammation in inflammatory bowel disease (IBD).

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News • ‘Reverse genetics’ system

New approach to norovirus vaccine and drug development

Researchers from Osaka have developed a simple and efficient system for understanding the functions of specific norovirus genes, providing new avenues for developing antivirals and vaccines.

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News • Intestinal nervous system

Allergies: central role of the "gut brain" discovered

New insights into the intestinal nervous system – or "gut brain" – open new avenues for advancing therapies for allergies, chronic inflammatory bowel diseases and irritable bowel…

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Article • Reshaping GI cancer care

Pathologists at the heart of precision oncology

Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…

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