Gastrointestinal tract

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News • Potential of immunotherapy explored

Surgery first for colon cancer? Not so fast, says new study

Immunotherapy prior to surgery is surprisingly effective for patients with a certain type of colorectal cancer (dMMR/MSI-H CRC). These new study results contrast current treatment regimens.

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News • Intestinal distress

Multiple sclerosis: a closer look at the gut microbiome

​Findings of bacteria with anti-inflammatory effects in the intestines of MS patients with no evidence of active disease indicate that diet, bacteria and disease progression are linked.

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Sponsored • Gastrointestinal endoscopy

Innovating products that balance patient safety and environmental concerns

As transparency surrounding the eco-footprint of hospitals becomes more important, medical device manufacturers must recognize the need for action to tackle global challenges, such as climate change.

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News • Increased infection risk

AMR: drug resistant bacteria can travel from gut to lung

A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.

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News • Bioprinting in cancer

3D printing patient-specific tumours

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models.

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Article • Diagnostic assistant systems

AI in endoscopy: helper, trainer – influencer?

Artificial intelligence (AI) is increasing its foothold in endoscopy. Although the algorithms often detect pathologies faster than humans, their use also generates new problems. PD Dr Alexander Hann…

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News • Colorectal cancer study

Covid-19 pandemic slashes CRC diagnoses by over 40%

The number of colorectal cancer (CRC) cases diagnosed fell dramatically by 40% in a year during the Covid-19 pandemic, new research presented at United European Gastroenterology (UEG) Week Virtual 2021 has shown. The research, which was conducted across multiple hospitals in Spain, compared data from the first year of the Covid-19 pandemic with data from the previous year. Of 1,385 cases of CRC…

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News • Altered bacterial function

Accumulation of drugs in the gut may reduce their effectiveness

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the medications’ effectiveness. These interactions - seen for many drugs including those used to treat depression, diabetes, and asthma - could help researchers to better understand how drug effectiveness and side-effects differ between individuals. The study is…

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News • Anatomy research

Why the appendix might not be so useless after all

Long considered an unnecessary organ, the appendix is now the focus of several studies that aim to better understand its role. Present in many mammals, including humans, it appears to have developed at least 16 times over the course of the evolutionary history of mammals, suggesting that its function must confer a positive selective advantage on those that have it. A new study carried out by…

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News • CADU vs cancer

Detecting oesophageal cancer with AI

Experts at University College London (UCL) and spinout company Odin Vision working with clinicians at UCLH have used artificial intelligence (AI) to help detect early signs of oesophageal cancer. The first procedure in the world using the AI technology was performed at University College Hospital by UCLH consultant gastroenterologist Dr Rehan Haidry. The system, called CADU, uses AI to support…

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News • More targeted treatment

AI could improve outcomes for bowel cancer patients

A test which uses artificial intelligence (AI) to measure proteins present in some patients with advanced bowel cancer could hold the key to more targeted treatment, according to new research. A team at the University of Leeds collaborated with researchers at Roche Diagnostics to develop the technique, which will help doctors and patients to decide on the best treatment options.

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News • Esophagitis

Lung cancer: Tailoring radiation therapy to reduce complications

For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment can cause severe, acute inflammation of the esophagus (esophagitis) in about one in five patients, requiring hospitalization and placement of a feeding tube. A team of radiation oncologists at Mass…

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News • Stopping the spread

Research sheds new light on pancreatic cancer metastasis

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death - it is the cancer's ability to evade detection and metastasize to other organs. A team of researchers at the College of Medicine at the University of Oklahoma has published a new study in the journal…

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'GI Genius'

FDA authorizes marketing of first AI device to help colon cancer early detection

The U.S. Food and Drug Administration authorized marketing of the GI Genius, the first device that uses artificial intelligence (AI) based on machine learning to assist clinicians in detecting lesions (such as polyps or suspected tumors) in the colon in real time during a colonoscopy. “Artificial intelligence has the potential to transform health care to better assist health care providers and…

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