early diagnosis

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Two-way magnetic resonance tuning

New double-contrast technique picks up small tumors on MRI

Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis, offers a significant advance in using magnetic resonance imaging (MRI) to pick out even very small tumors from normal tissue. The work is published in the journal Nature Nanotechnology. Chemical probes that produce a signal on MRI can be used to…

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Dynamic measurement of glucose in brain

New MRI technique for early detection of Alzheimer's

A research team co-led by a scientist at City University of Hong Kong (CityU) has discovered a new, non-invasive way to detect early-stage Alzheimer’s disease, helping patients get the necessary treatments around 10 years before any symptoms appear. In collaboration with Johns Hopkins University in the US, Dr Kannie Chan Wai-yan, Associate Professor in the Department of Biomedical Engineering…

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Nephritis as a marker

Kidney an early warning sign for severe COVID-19 cases

A course of action to early detect and treat severe courses of COVID-19 infections has been developed by an expert-team of the University Medical Center Goettingen (UMG). A simple urine test is intended to help medical professionals to recognize warning signs of future decompensation of COVID-19 infections earlier. With the help of a few parameters, the treatment of imminent complications can…

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Ultrasound monitoring

'Smart bra' to detect early-stage breast cancer

Students from EPFL in Switzerland teamed up with startup IcosaMed to develop the SmartBra – the first piece of smart clothing that can be used for cancer prevention. “Our smart-clothing technology is designed to detect cancer at the earliest stages. It uses a non-invasive, painless method based on frequent ultrasound monitoring,” says Hugo Vuillet, one of the students on the development…

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New sensor tech

A more reliable way to early detect lung tumours

People who are at high risk of developing lung cancer, such as heavy smokers, are routinely screened with computed tomography (CT), which can detect tumors in the lungs. However, this test has an extremely high rate of false positives, as it also picks up benign nodules in the lungs. Researchers at the Massachussetts Institute of Technology (MIT) have now developed a new approach to early…

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Oncology breakthrough

Blood test detects 50+ cancer types, often before symptoms show

Researchers have developed the first blood test that can accurately detect more than 50 types of cancer and identify in which tissue the cancer originated, often before there are any clinical signs or symptoms of the disease. In a paper published in the leading cancer journal Annals of Oncology, the researchers show that the test, which could eventually be used in national cancer screening…

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Acetone sensors

3D printing sensors for diabetes breath tests

The production of highly sensitive sensors is a complex process: it requires many different steps and the almost dust-free environment of special cleanrooms. A research team from Materials Science at Kiel University (CAU) and from Biomedical Engineering at the Technical University of Moldova has now developed a procedure to produce extremely sensitive and energy-efficient sensors using 3D…

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Enhancing cancer imaging

New contrast agent for early diagnosis of brain metastases

A group of researchers led by Leif Schröder from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent. To this end, the team uses a synthetic molecule that helps to detect the formation of new blood vessels, producing much more sophisticated…

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Assessment of brain tumour treatment response

Developing AI algorithms for earlier glioblastoma detection

Novel advanced imaging biomarkers are being developed in a series of studies at several UK centres that may lead to the earlier assessment of treatment response to glioblastoma (GBM) and a better survival rate. Through a number of clinical trials – and the application of artificial intelligence (AI) to retrospective data sets – the aim is to highlight approaches that will enable clinicians to…

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Prostate Urine Risk (PUR)

Urine test could reduce unnecessary prostate cancer biopsies

Unnecessary prostate cancer biopsies could be reduced by 60 per cent thanks to new research from the University of East Anglia (UEA). Researchers have developed new methods to identify biomarkers for prostate cancer by combining information from multiple parts of urine samples. It is hoped that the breakthrough could help large numbers of men avoid an unnecessary initial biopsy.

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COVID-19 in radiology

CT outperforms lab diagnosis for coronavirus infection

In a study of more than 1,000 patients published in Radiology, chest CT outperformed lab testing in the diagnosis of 2019 novel coronavirus disease (COVID-19). Researchers at Tongji Hospital in Wuhan, China, concluded that CT should be used as the primary screening tool for COVID-19. In the absence of specific therapeutic drugs or vaccines for COVID-19, it is essential to detect the disease at an…

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Early detection

Lung cancer screening: ESR welcomes release of NELSON trial results

The publication of the results of the Dutch-Belgian lung cancer screening trial (NELSON) supports recent calls to introduce lung cancer screening programmes throughout Europe. In light of the scientific evidence, lung cancer screening should be firmly embedded in any initiative launched by the European Commission and the Member States in the fight against cancer. As the leading cause of death…

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Not-so-smart algorithms

Skin cancer diagnosis apps: mostly unreliable and poorly regulated

Smartphone apps used as ‘early warning systems’ for skin cancer are poorly regulated and frequently cannot be relied upon to produce accurate results, according to new analysis by experts at the University of Birmingham. Skin cancer detection apps are designed to ensure that the right people seek medical attention by providing a risk assessment of a new or changing mole. These apps use…

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Contrast & new biomarker

Detecting early-stage cancer with targeted MRI

A new method to detect cancer in its early stages using a targeted MRI contrast agent that binds to proteins has been identified by a team of researchers led by Georgia State University Regents’ Professor Jenny Yang. In their study, published in the journal Science Advances, Yang and her colleagues at Georgia State and Emory University describe a newly identified biomarker for detection of…

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Early detection

Support for lung cancer screening gains momentum in Scotland

The need to consider a formal recommendation on early screening for lung cancer was acknowledged by the Cross Party Group for Cancer, held at the Scottish Parliament in Edinburgh in January. Attended by over 40 people representing patients, the medical community, and the pharmaceutical industry as well as political advisers and Members of the Scottish Parliament, the Group agreed to write to the…

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Decision support

AI can predict septic shock

Researchers at Linköping University (LiU) have developed an algorithm that can identify patients at a higher risk of septic shock, a life-threatening condition that is difficult for doctors to predict. At the same time, it is important to recognise the symptoms as early as possible, since early treatment increases the chance of survival. A group of LiU researchers is using artificial…

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Dementia diagnostics

Lack of sleep might throw off Alzheimer’s test

A preliminary study has found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer’s disease, in their blood than when they had a full, uninterrupted night of rest. The study is published in the January 8, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology. Tau is a protein found in…

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DeepMind to help human radiologists

Google-powered AI spots breast cancer

A computer algorithm has been shown to be as effective as human radiologists in spotting breast cancer from x-ray images. The international team behind the study, which includes researchers from Google Health, DeepMind, Imperial College London, the NHS and Northwestern University in the US, designed and trained an artificial intelligence (AI) model on mammography images from almost 29,000 women.…

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Machine learning for the mind

Astrophysics and AI team up for early dementia diagnosis

Crucial early diagnosis of dementia in general practice could improve thanks to a computer model designed in a collaboration between Brighton and Sussex Medical School (BSMS) and astrophysicists at the University of Sussex. Currently, only two-thirds of people with dementia in the UK receive a formal diagnosis, and many receive it late in the disease process, meaning that a large number are…

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Acoustofluidics

Saliva test to detect mouth and throat cancer earlier and easier

Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced, partly because their location makes them difficult to see during routine clinical exams. A report in The Journal of Molecular Diagnostics describes the use of acoustofluidics, a new non-invasive method that analyzes saliva for the presence of human papilloma virus…

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Early detection of colon cancer

When is the right time for the follow-up colonoscopy?

For the early detection of colorectal cancer, patients with statutory health insurance are entitled to two colonoscopies. If the first examination does not reveal any abnormal findings, a follow-up after a period of ten years is recommended. Scientists at the German Cancer Research Center are now systematically investigating when and how often tissue lesions are detected during the follow up…

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Sprue POCT

Celiac disease: faster detection through new method

Researchers from the University of Helsinki developed a novel diagnostic method for the rapid on-site measurement of antibodies from patient samples. Now they have applied this new method for the diagnostics of celiac disease, with promising results. Point-of-care (POC) testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is receiving care.…

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Medical robotics competition

Early detection of bowel cancer with a magnetic capsule

Five talented robotics specialists were selected by an international jury for the finals of the Kuka innovation competition from among 30 applications from all over the world. For the first time, the focus was put on medical robotics and the topic of “Healthy Living”. Each of the finalists were provided with the sensitive Kuka lightweight robot LBR Med and a 3D vision system from Roboception…

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Chemical clues

AI blood test can spot signs of brain tumour

Chemical analysis of blood samples, combined with an artificial intelligence program, could speed up the diagnosis of brain tumours, according to research presented at the 2019 NCRI Cancer Conference. Brain tumours tend to have ambiguous symptoms, such as headache or memory problems, and a brain scan is currently the only reliable way of diagnosing them. Researchers say their test, which works by…

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Presented at the NCRI cancer conference

Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells, according to new research presented at the 2019 NCRI Cancer Conference. Cancer cells produce proteins called antigens that trigger the body to make antibodies against them – autoantibodies. Researchers…

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