Keyword: early diagnosis

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Biomarker validation

Plodding toward a pancreatic cancer screening test

Pancreatic cancer is one of the most deadly types of malignancies, with a 5-year survival rate after late diagnosis of only about 5%. The majority of patients—about 80%—receive their diagnosis too late for surgery. The disease spreads quickly and resists chemotherapy. In short, there is an urgent need for diagnostic tools to identify this cancer in its earliest stages.

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Behavioral study

New understanding for autism through eye tracking

New research has uncovered compelling evidence that genetics plays a major role in how children look at the world and whether they have a preference for gazing at people’s eyes and faces or at objects. The discovery by researchers at Washington University School of Medicine in St. Louis and Emory University School of Medicine in Atlanta adds new detail to understanding the causes of autism…

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Oncotype

Updated breast cancer guidelines reinforce genomic testing

Genomic Health announced that the 15th St. Gallen International Breast Cancer Conference Expert Panel endorsed the use of genomic tests in early-stage breast cancer and recognised the Oncotype DX Breast Recurrence Score test for its prognostic ability as well as its value in guiding treatment decisions on adjuvant chemotherapy for patients with early-stage, endocrine sensitive, invasive breast…

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Breath Biopsy platform

Owlstone Medical CEO Billy Boyle wins Royal Academy of Engineering’s Silver Medal

Billy Boyle, Founder and CEO of Owlstone Medical, a diagnostics company developing a breathalyzer for disease, is to be awarded the Royal Academy of Engineering’s prestigious Silver Medal. The award recognizes engineer Billy’s work in spearheading the development of the company’s Breath Biopsy platform and driving a vision to save 100,000 lives and $1.5 billion in healthcare costs.

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Neuropathology

Detecting Alzheimer's disease before symptoms emerge

Long before symptoms of Alzheimer's disease become apparent to patients and their families, biological changes are occurring within the brain. Amyloid plaques, which are clusters of protein fragments, along with tangles of protein known as tau, form in the brain and grow in number, eventually getting in the way of the brain's ability to function. These biological changes can be detected early in…

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Brain pathology

New insights into early cognitive markers of Alzheimer's

New research led by the University of Hertfordshire, may significantly change the understanding of cognitive processes that are most impaired at very early stages of Alzheimer's disease. The findings could potentially be used to detect the condition at an earlier stage and improve diagnostic accuracy, by creating new cognitive tests that are more sensitive to brain pathology than ones currently…

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Ophthalmology

New eye test detects earliest signs of glaucoma

A simple eye test could help solve the biggest global cause of irreversible blindness, glaucoma. In clinical trials, the pioneering diagnostic test - developed by researchers at UCL Institute of Ophthalmology and the Western Eye Hospital - allowed doctors to see individual nerve cell death in the back of the eye.

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Predict early stages of Alzheimer’s disease

Researchers from Columbia University Medical Center (CUMC), New York State Psychiatric Institute, and NewYork-Presbyterian reported that an odor identification test may prove useful in predicting cognitive decline and detecting early-stage Alzheimer’s disease. Their two studies, presented at the Alzheimer’s Association’s International Conference in Toronto, Canada, suggest that the…