Genetics

Article • Personalizing stroke care

Advancing genomic medicine from promise to practice with digital technology

Stroke patients in four NHS hospitals are now receiving genetic tests that determine whether a commonly prescribed drug will work for them – a breakthrough that could transform treatment for…

News • Research

Stuttgart researchers enhance CRISPR for cellular analysis

University of Stuttgart scientists develop enhanced CRISPR technique that makes genetic loss-of-function analyses more efficient and reproducible for medical research.

News • Virology

HIV genome integration mechanism decoded by German researchers

German researchers discover how HIV selects genome integration targets using RNA:DNA hybrids as guides, revealing new therapeutic approaches for controlling viral reservoirs.

News • Prediction of treatment sensitivity

Personalising prostate cancer treatment through molecular testing

A new study shows that a gene expression test on routinely collected prostate tissue can help guide therapy choices for prostate cancer patients whose cancer has spread to other parts of the body.

News • Genomics

Chronic cough: study points to neurological mechanisms

Chronic cough affects approximately 1 in 10 adults in the UK, but the causes are often unknown and treatment options limited. Now, a new study has identified neurological mechanisms as key drivers.

News • Chromatin remodeling

New protein targets for cancer treatments

A research team at the University of Geneva has identified two new proteins that regulate gene expression, a discovery that could pave the way for new cancer and brain disorder treatments.

News • Genetic signature mapping

Diagnosing Parkinson’s from a blood sample

In a world first, researchers have identified a set of biomarkers that could someday make it easy to spot Parkinson's disease in a patient’s blood sample.

News • Machine learning analysis

Cancer genomics: new ML tool weeds out false positives

A major challenge in cancer genomics is separating meaningful mutations from false positives. A new tool uses machine learning to significantly reduce these errors.

News • Promising protein analysis tool

New blood test to enable rapid diagnosis of rare genetic diseases

An Australian research team has developed a blood-based method of analysing thousands of proteins in a single, untargeted test. This potentially enables rapid diagnosis of many rare genetic diseases.

News • Appeal for tailored care approaches

Breast cancer: Study reveals ethnic differences in development and outcomes

When it comes to breast cancer, ethnic differences matter, putting some women at a significantly higher risk, a new study finds. Genetic ancestry should therefore be considered as a risk factor.

News • Intestinal disease diagnosis

Next-generation tools find infections missed by standard tests

A University of Liverpool study has used advanced genetic and genomic techniques to offer a major step forward in understanding and diagnosing infectious intestinal diseases.

News • Amyotrophic lateral sclerosis

New insights on ALS onset opens paths to earlier treatment

New research shows that dysfunction in the mitochondria linked to amyotrophic lateral sclerosis (ALS) occurs before the cells show other signs of disease, which was not previously known.

News • New insights on CLEC5A

Immune gene discovery could prevent memory loss in Alzheimer's patients

A gene once believed to fight only viral infections could also hold the key to preventing memory loss in Alzheimer’s patients, a new study finds. This paves the way for new drug developments.

Anastasia Khvorova, PhD

Pioneering work in the field of RNA-based therapies for Huntington's disease

RNA researcher Anastasia Khvorova, PhD, professor of RNA therapeutics at UMass Chan Medical School, will receive this year's Else Kröner Fresenius Prize for Medical Research on May 15, 2025. The award ceremony will be a part of the festive event together with the Fresenius SE & Co. KGaA celebrating the 100th birthday of Else Kröner, at the Städel Museum in Frankfurt am Main.

News • Swedish national initiative

Precision omics to boost data-driven medicine

The new national Precision Omics Initiative Sweden (PROMISE) aims to generate and integrate extensive molecular data to create a model for precision medicine implementation for Sweden.

Maartje Huijbers

Combining research work and vice dean duties

As of May 1st, Maartje Huijbers holds the position of vice dean of research, a new position within the Leiden University Medical Center (LUMC). Huijbers is associate professor and research group leader in the Department of Human Genetics and the Department of Neurology. She will combine her work as a scientist with the position of vice dean.

News • Actionable genetic variants

Look into "Viking Genes" shows benefits of personalised health insights

A research project investigating the genetics and health of volunteers from the Hebrides, Shetland or Orkney shows how distinct genetic populations can benefit from tailored screening programmes.

News • Research on RAD51 biomarker

Next-generation sequencing for personalizing prostate cancer treatment

Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.

News • Study on ventricular shapes

How heart shape links to cardiovascular disease risk

Researchers have published findings that show the genetic structure of the heart’s shape may offer new insights into individual heart health.

Taipei showcases cutting-edge medical devices & diagnostics at Medica 2024

Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.

News • Irritable bowel syndrome

How genes determine the effectiveness of diets in irritable bowel syndrome

A European research team has now shown that dietary measures are more effective in IBS patients with defects in carbohydrate digestion genes than in those without these changes.

News • Hibernation

Genetic Discovery in Syrian Hamsters Unlocks Secret to Surviving Extreme Cold

A study led by Assistant Professor Masamitsu Sone and Professor Yoshifumi Yamaguchi from Hokkaido University, Japan, has uncovered a crucial gene that enables hibernating Syrian hamsters (Mesocricetus auratus) to prevent cold-induced cell death. The research was published in the journal Cell Death and Disease.

News • DNA damage response

New insights into the DNA damage response

The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with RNA metabolism.

News • Gene Therapy

Innovative gene therapy for hemophilia

Until now, those affected have had to inject the missing coagulation factor proteins themselves several times a week. Gene therapy now offers those affected the prospect of an improvement: the therapeutic agent is administered as a single intravenous injection.

News • Hard to treat cancers

KRAS “degrader” could lead to treatment for millions of cancer patients

A newfound molecule, called ACBI3, could potentially lead to new therapies against hard-to-treat cancers, improving outcomes for all patients with cancers caused by KRAS mutations.

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