Antimicrobial resistance (AMR) is becoming more prevalent around the world, constituting a serious threat to public health. When bacteria acquire resistance against antibiotics, common medical procedures – for example, in surgery – become impossible due to the high infection risk. Keep reading to find out about AMR research, development of new antibiotics and antibiotic alternatives.
Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).
Carriers of a specific bacteria have a 14% chance of developing an antibiotic resistant infection with 30 days of hospitalisation, according to new research from Amsterdam.
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.
Periprosthetic infections and revisions are on the rise in Germany and worldwide, with significant consequences for affected patients as well as for the healthcare systems. Precisely because the number of patients at higher risk of infection in arthroplasty continues to rise, attention is increasingly focused on how this dreaded complication can be avoided.
Antibiotic prescribing in primary care could be monitored using health insurance data. And reduced with a simple test.
A new study could one day help health workers determine whether bacteria of the species Streptococcus pneumoniae, which cause meningitis, are resistant to antibiotics.
Bacteriophages – viruses that kill bacteria – could be a solution for fighting antibiotic-resistant pathogens, French researchers have developed a model to better predict their efficacy.
The search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.
Climate change and antimicrobial resistance (AMR) are forming an alarming alliance: Global warming creates new breeding grounds for resistant bacteria. A serious and very real threat to public health – but not quite the doomsday scenario some might make it out to be, says Prof Sabiha Essack from the University of KwaZulu-Natal in Durban, South Africa.
Finding the right antibiotic dose is akin to a Goldilocks problem: give too little, and the infection will persist; too much, and side-effects will override the benefits of the therapy. To get it “just right”, Prof Dr Birgit Koch talks about dosing optimisation in the clinical setting.
Researchers find that drug-resistant bacteria can be distinguished from non-resistant bacteria based on structural changes evident in electron microscope images with high accuracy using deep learning.
An international team of scientists have shown that small and large bacterial populations follow qualitatively different evolutionary paths to develop antibiotic resistance.
A type of the antibiotic resistant superbug MRSA arose in nature long before the use of antibiotics in humans and livestock, which has traditionally been blamed for its emergence.
The long-term impact of the coronavirus pandemic on antimicrobial resistance remains difficult to predict. Infectious diseases consultant Professor Alison Holmes reflects on Covid-19's effect on antibiotic use in hospitals and beyond.
For many years, antibiotic consumption in France was at an alarming level, resulting in a worryingly constant increase in antibiotic resistance However, a newly-enforced strict national plan appears to be having effect.
To counteract the spread of resistant germs, researchers have developed new drug candidates that are able to render one of the most important hospital germs harmless.
According to scientists at Rice University’s George R. Brown School of Engineering, discarded polystyrene broken down into microplastics provides a cozy home not only for microbes and chemical contaminants but also for the free-floating genetic materials that deliver to bacteria the gift of resistance.
