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Antibiotic resistance

Antimicrobial resistance (AMR) is becoming more prevalent around the world, constituting a serious threat to public health. When bacteria acquire resistance against antibiotics, common medical procedures – for example, in surgery – become impossible due to the high infection risk. Keep reading to find out about AMR research, development of new antibiotics and antibiotic alternatives.

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News • Seniors’ use of antibiotics halved

Study shows benefits of antibiotic stewardship in UTI management

An international study has shown how a decision tool for health professionals has proved capable of halving the use of antibiotics against urinary tract infections while maintaining patient safety.

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News • MTX in the mix

Researchers develop novel therapy for vancomycin-resistant infections

Researchers from the US, Singapore and Geneva have developed a novel combination therapy using an anticancer agent for treating vancomycin-resistant Enterococcus faecalis (VRE).

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News • Infectious disease research

Hidden bacteria increases risk of antimicrobial resistant infection in hospital patients

Carriers of a specific bacteria have a 14% chance of developing an antibiotic resistant infection with 30 days of hospitalisation, according to new research from Amsterdam.

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News • Antibacterial compound research

Developing antibiotics that target multiple-drug-resistant bacteria

Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.

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News • Driving genes of AMR in focus

Tracking the global spread of antimicrobial resistance

An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.

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News • Increased infection risk

AMR: drug resistant bacteria can travel from gut to lung

A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.

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Sponsored • Periprosthetic protection

Bone cements containing antibiotics for infection prophylaxis – quo vadis?

Periprosthetic infections and revisions are on the rise in Germany and worldwide, with significant consequences for affected patients as well as for the healthcare systems. Precisely because the number of patients at higher risk of infection in arthroplasty continues to rise, attention is increasingly focused on how this dreaded complication can be avoided.

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Article • Antimicrobial resistance development

AMR and climate change: a worrying dual threat to global health

Climate change and antimicrobial resistance (AMR) are forming an alarming alliance: Global warming creates new breeding grounds for resistant bacteria. A serious and very real threat to public health – but not quite the doomsday scenario some might make it out to be, says Prof Sabiha Essack from the University of KwaZulu-Natal in Durban, South Africa.

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Article • A potentially devastating impact

Covid-19 alters antibiotic use

The long-term impact of the coronavirus pandemic on antimicrobial resistance remains difficult to predict. Infectious diseases consultant Professor Alison Holmes reflects on Covid-19's effect on antibiotic use in hospitals and beyond.

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News • Hazardous materials

Microplastic pollution aids antibiotic resistance

According to scientists at Rice University’s George R. Brown School of Engineering, discarded polystyrene broken down into microplastics provides a cozy home not only for microbes and chemical contaminants but also for the free-floating genetic materials that deliver to bacteria the gift of resistance.

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News • Resistance mechanism discovered

How staphylococci protect themselves against antibiotics

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat. Researchers at the University of Bonn have uncovered an ingenious way in which a certain strain of Staphylococcus aureus protects itself against the important antibiotic vancomycin. The results have now been published in the journal Microbiology Spectrum.

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