Immune system

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News • Explanation for neurological symptoms

Coronavirus does not infect the brain, but...

How does a coronavirus infection cause neurological symptoms such as headaches, memory problems, and fatigue? A new study points to a different reason than previously assumed.

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News • Pan-cancer proteogenomics

Characterizing the immune landscape in cancer

Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.

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News • Increasing cell visibility

Making cancer easier to find and destroy for the immune system

Researchers in Japan and the US have developed technology to robustly augment the amount of MHC class I molecules in cancer cells. This makes them easier to find and destroy for the immune system.

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News • Focus on autoreactive T lymphocytes

Guillain-Barré Syndrome: researchers find cause

The underlying mechanisms of Guillain-​Barré Syndrome (GBS) have remained largely unknown until now. New research now uncovers a pivotal aspect of GBS pathophysiology.

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News • Lung development research

Immune cell insights for better treatments of respiratory diseases

Researchers have created a first-of-its-kind immune cell atlas of the developing lung, revealing coordination between the immune and respiratory systems much earlier than previously thought.

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News • Cytokine reference

New “dictionary” reveals suprising complexity of immune responses

Scientists map the effects of 86 immune-signaling molecules called cytokines on every major immune cell type, creating a reference for studying the inner workings of the immune system.

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Article • Cancer patients at risk

Blood test detects risk of neurotoxicity from CAR T-cell therapy

Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…

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