Immune system

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News • Patient-derived samples

New ‘explant’ technique predicts breast cancer therapy response

A new study measured how well breast cancer patients’ tumour ‘explants’ respond to chemotherapy or HER2 antibody therapy in the laboratory. This could help improve clinical outcomes.

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News • Checkpoint inhibitor immunotherapy efficacy

AI tool uses routine blood tests to predict cancer immunotherapy response

Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.

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News • Immunology

Researchers discover new type of anticancer T-cell

A molecule called MR1 (MHC Class I-related Molecule 1) enables a newly-discovered type of T-cells to sense differences in the metabolism that occur when cells become cancerous.

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News • Research into new therapies

How natural killer cells could fight leukemia more effectively

Researchers now succeeded in making leukemia-specific immune cells less sensitive to the influence of tumor cells, thereby significantly increasing their effectiveness.

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News • New approach to combat treatment resistance

How chemotherapy affects ovarian cancer tumours

Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.

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News • Dermatology

Exploring fibroblast subtypes and skin cancer aggressiveness

New insights into the previously unknown diversity of cancer-associated fibroblasts in basal cell carcinoma, squamous cell carcinoma and melanoma could pave the way for new therapies.

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