Immune system

News • Potential treatment strategy

Vitiligo: pigment cells could be reactivated, study finds

The characteristic white skin patches of vitiligo are caused by a lack of skin pigments – or so we thought. New research suggests that melanocytes merely enter a dormant state – from which they…

News • New insights on TILs

Immune cells in the tumour microenvironment: Better near than far away?

Tumour-infiltrating lymphocytes are key players in cancer immunotherapy. New research explores the role of location in the tumour microenvironment – knowledge that could help improve treatments.

News • Study finds mixed associations

Does breastfeeding prevent childhood allergies? It's complicated

Breastfeeding is recognized for its role in supporting a child's growth and immune system development. However, new research paints a more nuanced picture on its effect on childhood allergy.

News • Neuroprotective antiviral state in the CNS

Remarkable early warning system helps the brain prepare for a viral attack

Virus-associated molecules in the foot are enough to trigger the network: Research reveals a remarkable mechanism, in which the brain prepares for a potential viral attack within hours of infection.

News • Premature ovarian insufficiency

Immunotherapy may temporarily restore fertility in premature menopause patients

A pilot study shows that immunotherapy may enable stimulation of egg maturation in women with premature menopause. Three out of ten women gave birth to healthy babies following the treatment.

News • Treatment-resistant tumours

Researchers tear off "invisibility cloak" of colon cancer

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy — a fundamental breakthrough.

News • Reviving exhausted immune cells

A new way to boost cancer immunotherapy

A Taiwanese research team found that BET inhibitors can restore exhausted T cells by reprogramming their metabolism – a potential new strategy for cancer immunotherapy.

Prof. Johanna Joyce

Advancing cancer research across Europe and beyond

Prof. Johanna Joyce has begun her two-year term as President of the European Association for Cancer Research (EACR), a global community of scientists and clinicians dedicated to advancing the scientific understanding of cancer and its application to improve patient care.

News • Effects on autoimmune disease

Will pregnancy make myasthenia gravis worse? Study sheds new light

Many women with myasthenia gravis choose not to have children due to fear that the disease will get worse during or after pregnancy. Now, a study investigated the connection to the autoimmune disease.

News • Targeted immunotherapy

Implantable cytokine factories to help treat ovarian cancer

Researchers have reported results from a first-in-human trial evaluating a novel cell-based platform for localized delivery of interleukin-2 (IL-2) in patients with advanced ovarian cancer.

News • Immuno-Oncology

Killer cells caught in the act: a 3D view of T lymphocytes

Researchers have used cryo-expansion microscopy to capture cytotoxic T lymphocytes destroying cancer cells in unprecedented 3D detail, opening new paths in immuno-oncology.

News • Lowering tissue reactivity

Towards more biocompatible brain implants

Neural implants show great potential, but the brain's reaction to foreign objects remains a challenge. New research insights could now pave the way for more biocompatible brain implants.

News • Transplant organ acceptance

“Immune priming” prevents donor liver rejection

A new technique to “prime” a patient's immune system before liver transplantation has proven itself in a first-in-human clinical trial to successfully prevent transplant rejection.

News • Immunology

How obesity impairs vaccine response

Being overweight can reduce vaccine effectiveness, new research finds. The findings explore differences in immune response, and may lead to more effective vaccines for patients with obesity.

News • Prediction of treatment response

Colon and rectal cancer: new biomarker shows which patients benefit from immunotherapy

A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.

News • Study explores reason for health benefits

How sauna bathing boosts the body's immune responses

Regular sauna bathing has been associated with several beneficial health effects. A new study from Finland may help explain how these effects develop in the body.

News • Impact on longevity and cancer

“The thymus has been overlooked for decades”

Two new studies explore the role of the thymus – a small organ in the chest, and possibly a missing piece in explaining why people age differently, and why cancer treatments fail in some patients.

News • Critical role of NFAT

Preventing pregnancy complications with new immune insights

A hidden immune circuit in the uterus revealed: Researchers have discovered a crucial immune switch that sheds light on preeclampsia and early pregnancy failure.

News • Adhesive microgel-based coating

A spray-on shield to prevent transplant rejection

Korean researchers are developing a “spray shield that adheres to transplant organs” and reduces the burden on patients taking lifelong immunosuppressants to prevent transplant rejection.

News • Research on dopaminergic neurons

Immunotherapy to prevent neuron loss in Parkinson’s disease

Promising new research points to a new immunotherapy approach that could help preserve viable neurons in people with Parkinson’s disease.

News • Focus on tumor STAT1 acetylation

How cancer cells learn under pressure to evade immunotherapy

Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.

News • Immune response to viral infection

Multiple sclerosis: how EBV can evoke nerve damage

The immune system’s reaction to the common Epstein-Barr virus (EBV) can ultimately damage the brain and contribute to multiple sclerosis (MS), a new study shows.

News • Drivers of gray matter injury

Multiple sclerosis: Promising biomarker linked to progression and brain inflammation

A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.

News • Intestinal nervous system

Allergies: central role of the "gut brain" discovered

New insights into the intestinal nervous system – or "gut brain" – open new avenues for advancing therapies for allergies, chronic inflammatory bowel diseases and irritable bowel syndrome.

News • Dual-barrier tumours

How colorectal cancer evades immunotherapy (and what to do about it)

Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.

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