Bacteria

Sponsored • Product of the month

New test with simplified preanalytics for simultaneous detection of GDH and toxins of Clostridioides difficile in compliance with recommendations

Sofia 2 C. difficile FIA is a new solution to provide reliable and rapid test results with high clinical relevance before empiric therapy decisions are implemented.

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Elusive variants

Rare genetic markers of drug-resistant tuberculosis identified

The search for rare mutations in bacterial genome could lead to better diagnostics and treatments – reducing morbidity caused by the deadly disease.

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mhealth

Smartphone-powered microchip for at-home diagnostic testing

Researchers developed a new microfluidic chip with broad applications for detecting viruses, pathogens, bacteria and other biomarkers in liquid samples.

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Antimicrobial resistance development

AMR and climate change: a worrying dual threat to global health

Climate change and antimicrobial resistance (AMR) are forming an alarming alliance: Global warming creates new breeding grounds for resistant bacteria, which challenge human, animal, and…

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Metabolic disorders

Decoding a direct dialog between gut microbiota and brain

Hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly.

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Identifying antimicrobials

Automated CAST-R system helps to fight blood infections

When treating acute infections, health care providers must quickly identify the best antibiotics for fighting the infection. An automated system provides swift, accurate results for determining the…

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Microbiology

Using 3D printing technique to create biofilms

Researchers at the University of Rochester, and Delft University of Technology in the Netherlands recently developed a 3D printing technique to engineer and study biofilms—three-dimensional communities of microorganisms, such as bacteria, that adhere to surfaces. The research provides important information for creating synthetic materials and in developing drugs to fight the negative effects of…

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Resistance mechanism discovered

How staphylococci protect themselves against antibiotics

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat. Researchers at the University of Bonn have uncovered an ingenious way in which a certain strain of Staphylococcus aureus protects itself against the important antibiotic vancomycin. The results have now been published in the journal Microbiology Spectrum.

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Altered bacterial function

Accumulation of drugs in the gut may reduce their effectiveness

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the medications’ effectiveness. These interactions - seen for many drugs including those used to treat depression, diabetes, and asthma - could help researchers to better understand how drug effectiveness and side-effects differ between individuals. The study is…

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Population bottlenecks

Random effects make it difficult to optimise antibiotic therapy

Antibiotic-resistant pathogens have become one of the greatest threats to public health. The basic mechanisms of resistance evolution have been well studied experimentally and are an important research field at Kiel University. An important factor in this context, but one that has received little attention so far, is the population size of the respective pathogen. Over the course of an infection…

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A new tool to combat superbugs

Defeating antibiotic resistant bacteria with 'molecular tweezers'

Antibiotic resistant bacteria are a looming super threat – heralding a time when our drugs will no longer be effective against prevalent infections. Hospitals are already coping with treatment-resistant bacterial infections. Cognizant of the threat and thinking outside the box, BGU scientists and German and American colleagues have developed a pair of 'molecular tweezers' to destroy the biofilm…

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