Electron microscopy
Replication cycle of SARS-CoV-2 in 3D
In a new study, researchers performed a detailed imaging analysis to determine how the virus reprograms infected cells.
Microscopy
Cancer diagnostics
A glimpse into the tumor in 3D
In order to analyze tumors, they have to be cut into thin slices. Now, a new technology has been developed that makes pieces of the tumor visible in 3D without cutting them.
"Enhance that"
New algorithm sharpens focus of cryo-electron microscopes
Scientists have developed a tool that improves the resolution and accuracy of powerful microscopes that are used to reveal insights into biology and medicine. In a study published in Nature Methods, a multi-institutional team led by Tom Terwilliger from the New Mexico Consortium and including researchers from Lawrence Berkeley National Laboratory (Berkeley Lab) demonstrates how a new computer…
Microbiome study
Do microscope eyepieces pose an infection risk?
Light microscope for viewing microorganisms such as bacteria and fungi are commonly found in scientific laboratories. A research team from Furtwangen University, the University of Tübingen and Carl Zeiss Vision International GmbH, Aalen, examined more closely their role as potential vectors of infectious pathogens. „Very little was known about this until now," explains the head of the…
The Art of Science
Olympus announced Global Image of the Year Award Winners
Olympus has announced the winners of its first Global Image of the Year Life Science Light Microscopy Award, a competition that recognizes the best in life science imaging worldwide.
Smart algorithm
Automated analysis of whole brain vasculature
Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Research Centre for Environmental Health and the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels – right down to the finest capillaries – including any pathological changes. So…
Imaging the brain
Ultra-miniaturized endoscope produces HQ images
Johns Hopkins engineers have created a new lens-free ultra-miniaturized endoscope, the size of a few human hairs in width, that is less bulky and can produce higher quality images. Their findings were published in Science Advances. “Usually, you have sacrifice either size or image quality. We’ve been able to achieve both with our microendoscope,” says Mark Foster, an associate professor of…
Raising the bar
A new ultra-compact microscopy camera
The MKC-X800 ultra-compact camera is a new addition to Ikegami’s range of medical imaging equipment, which, the firm reports, sets higher than ever standards of imaging quality to capture the precise colour and image detail of surgical operations. Measuring just 28x28x52mm WHD and weighing 100g, it can be mounted on a surgical microscope, lightweight support stand or boom. With its 4K-native…
In focus
Universal algorithm set to boost microscopes
Scientists from EPFL have developed an algorithm that can determine whether a super-resolution microscope is operating at maximum resolution based on a single image. The method is compatible with all types of microscopes and could one day be a standard feature of automated models. Thanks to the advent of super-resolution microscopes some 30 years ago, scientists can observe subcellular…
Collagen unter the microscope
Seeing the pattern beneath the skin
As the largest organ of the human body, our skin is astounding. It protects us from infection, endures radiation, senses temperature, and is flexible enough to withstand our everyday activities. What holds this all together is the protein we all know and love: collagen. In a paper published in Scientific Reports a team from Japan found for the first time that collagen in the skin is organized in…
WLAN-capability
Turning microscopes in the classroom into a wireless imaging system
Today’s educational landscape is changing rapidly thanks to technological advances. Introducing wireless capabilities to science classrooms enables lecturers to teach and students to learn in an engaging digital environment that promotes teamwork. Equipped with a WLAN-capable Olympus EP50 camera, every microscope in a classroom becomes a wireless imaging system. Using its own WLAN signal*, the…
Photonics
Rapid tissue analysis: Laser light detects tumors
Cancer - this diagnosis affects almost every second German at some point in his life. It is the second most frequent cause of death in Germany. But the earlier the disease is diagnosed, the greater are the chances of surviving it. A team of researchers from Jena present a groundbreaking new method for the rapid, gentle and reliable detection of tumors with laser light at the leading trade fair…
Ultra-thin and polished
Next-generation objectives push boundaries of microscopy
Olympus has broken down barriers to imaging quality with the launch of its next-generation objectives. The breakthrough polishing technique enables the company to produce ultra-thin lenses that overcome the traditional trade-off between numerical aperture (NA), flatness and chromatic correction – enabling all three parameters to be significantly improved. Olympus has harnessed this proprietary…
Product of the Month
Make Your Application Digital – with the EP50 Stand-alone Network Camera
Bring your application into the digital world and combine the new Olympus EP50 camera with our wide range of microscopes. Add the accesoires you need and choose the kit that fits your requirements. The Olympus EP50 camera makes digital imaging of microscopy samples a fast and engaging experience and is ready to use in seconds. The EP50 camera adds sophisticated digital features to any microscope…
Microscopy in the body
The next generation of endoscopy technology
Biotechnologists, physicists, and medical researchers at FAU have developed technology for microscopic imaging in living organisms. A miniaturised multi-photon microscope, which could be used in an endoscope in future, excites the body’s own molecules to illuminate and enables cells and tissue structures to be imaged without the use of synthetic contrast agents. The findings have now been…
Non-invasive diagnostics
Detecting bladder cancer with atomic force microscopy
A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder. In the first successful use of atomic force microscopy (AFM) for clinical diagnostic purposes, the researchers have been able to identify signature features…
Smartphone detection
Spectrometry? There's an app for that!
Checking a lump for malignancy, finding out if food is fresh, just with your smartphone? It’s possible, according to Eindhoven University of Technology researchers in the Netherlands. Their recently presented spectrometer is small enough to insert into a smartphone. This device is not yet ready for use on a big scale, Professor Andrea Fiore, supervisor of the Eindhoven research team points out.…
Product of the month
Olympus Color Cameras – Confidence in Your Images
Let your images tell the story with Olympus’ high-quality digital color cameras for microscopy in hospitals. With crisp, noise-free images and 4K UHD live viewing, the Olympus UC90 and SC180 brightfield cameras capture all the details you see through the oculars – enabling easy on-screen viewing or sharing in large-screen presentations.
Product of the Month
Olympus BX46 microscope – Protecting operators with ergonomics
In microscopy, ergonomics is particularly important as long periods at the microscope put unusually specific constraints on posture. In certain roles, such as in pathology, microscopy forms a significant part of daily activities – sometimes taking up more than 50% of working hours. Protecting operators by preventing injuries is of utmost importance in these routine microscopy roles.
Competition
Olympus Image of the Year – Celebrating art in science
Olympus’ Image of the Year Award for light microscopy in Europe recognizes the very best in life science imaging. Inspired by the beauty and breadth of images submitted for Image of the Year 2017, Olympus is now continuing its quest for the best light microscopy art in 2018. For the chance to win one of three prizes, applicants can submit life science light microscopy images to…
Product of the Month
cellSens 2.1 – More Imaging for Less
Olympus cellSens 2.1 offers improved capabilities for flexible camera and microscope control and enables researchers to create sharp, noise-free images in less time. Helping to drive microscopy forward, cellSens 2.1 speeds up image analysis and features new image acquisition tools at a lower cost. In addition, existing cellSens users may be eligible for a free upgrade to cellSens 2.1. cellSens…
Nanoscale visualization
Laser light shows X-ray holographic images of viruses
Holography, like photography, is a way to record the world around us. Both use light to make recordings, but instead of two-dimensional photos, holograms reproduce three-dimensional shapes. The shape is inferred from the patterns that form after light ricochets off an object and interferes with another light wave that serves as a reference. When created with X-ray light, holography can be an…
Innovation
Show every detail at every magnification with Olympus’ SC180 4K camera
Facilitating precise sample documentation and audience engagement, Olympus’ 18 megapixel SC180 camera shows unprecedented detail, especially at low magnifications. The easy-to-use and cost-effective SC180 camera reinforces Olympus’ commitment to making 4K Microscopy the new standard.
Microscopy
Olympus BX53 Microscope – Stay comfortable while you work
In the modern world, ergonomics is everywhere – and when microscopy is a big part of your daily routine, ergonomics should be at the forefront. Olympus’ BX53 microscope is designed with laboratory professionals in mind, allowing the microscope to be customized so that every user can work in their ideal posture.
Going digital
Time to speed up adoption of digital pathology
Early adoption of image analytical tools and artificial intelligence are crucial if health systems across Europe are to see the full potential of digital pathology, according to a leading expert. While a growing number of European institutions are beginning to embrace digital pathology, Professor Johan Lundin remains concerned about the slow pace of progress. He acknowledges that more…