Many procedures in diagnostic imaging would be impossible without contrast agents: they open up insights into vascular structures, show stenoses, inflammations, aneurysms and more. However, reports about side effects – especially with gadolinium-based contrast media – cause uncertainty among many patients.
Photon-counting detector CT reduces the amount of contrast needed for CT angiography (CTA) while maintaining image quality, according to a new study published in Radiology: Cardiothoracic Imaging.
On March 31st, 2022, a city-wide lockdown to curtail the spread of the Covid-19 virus in Shanghai, China, shuttered the GE Healthcare manufacturing facility that produces 80% of the global supply of iodinated contrast media agents iohexol (Omnipaque) and lodixanol (Visipaque). Although the plant was able to operate at 50% capacity by mid-May, the shutdown resulted in a substantial contrast media…
A research team has investigated how contrast agents disperse inside cells. This could improve the assessment and further development of these agents and contribute to future medical diagnostics.
A new understanding of the 'swallow-tail', an anatomical landmark in the brain, could pave the way for earlier detection of Parkinson's disease.
Researchers are seeking alternatives to gadolinium-based contrast agents (GBCAs) to help raise levels of patient safety. An open hybrid session at ECR in Vienna heard how research across several centres has been examining the options of new approaches to reduce reliance on GBCAs.
Contrast-enhanced mammography (CEM) has gone a long way since it was first approved by the Food and Drug Administration (FDA) in 2011. An Italian expert explained how useful the modality has become in breast imaging in a dedicated course at ECR 2022.
Advances in image post-processing and contrast-enhanced techniques have widened the scope of possibilities for MRI and ultrasound vascular imaging, experts showed in a dedicated course at the ECR Overture.
An algorithm built to assess scar patterns in patient heart tissue can predict potentially life-threatening arrhythmias more accurately than doctors can.
Contrast agents in the wastewater and power-hungry imaging systems: The eco-footprint of healthcare is huge, and radiology departments are among the main culprits. An expert panel at the ECR Overture explored ways to make the field “greener”.
A new study from the University of Surrey and University College London has revealed that treatment for heart attacks could be improved thanks to a novel method of evaluating heart function using contrast-based MRI scans. According to the British Heart Foundation, heart and circulatory diseases cause more than a quarter (27 per cent) of all deaths in the UK, which equates to more than 160,000…
The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke,…
Magnetic resonance imaging (MRI) is widely used to identify the narrowing or blockage of blood vessels. Contrast agents improve the visibility of the structures and offer more accurate information of vascular conditions such as vascular blockage and stenosis. Commonly used gadolinium-based contrast agents must be administered in chelated forms due to the gadolinium ions' high toxicity and pose…
The accuracy of breast cancer diagnosis via diffusion-tensor imaging (DTI) was equivalent both before and after the administration of a gadolinium-based contrast agent (GBCA), despite a value change in DTI parameters, finds a new research article. “However,” wrote first author Anabel M. Scaranelo of Princess Margaret Cancer Centre’s breast imaging division in Toronto, “the limitations in…
Manganese and iron oxide contrast agents can replace gadolinium-based contrast agents (GBCA) in a number of MRI examinations, but gadolinium remains a strong candidate when properly indicated, especially with AI-driven dose reduction and advances to increase relaxivity, a French expert explained at ECR 2020. GBCA have been MRI companions for many years. In France, 30% of all MR examinations are…
Researchers at the University of Zurich have developed a new X-ray contrast agent which is easier to use and distributes into all blood vessels more reliably, increasing the precision of vascular imaging. This reduces the number of animals required in research experiments. Various diseases in humans and animals – such as tumors, strokes or chronic kidney disease – damage the blood vessels.…
Early detection of tumors is extremely important in treating cancer. A new technique developed by researchers at the University of California, Davis, offers a significant advance in using magnetic resonance imaging (MRI) to pick out even very small tumors from normal tissue. The work is published in the journal Nature Nanotechnology. Chemical probes that produce a signal on MRI can be used to…
A group of researchers led by Leif Schröder from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent. To this end, the team uses a synthetic molecule that helps to detect the formation of new blood vessels, producing much more sophisticated…
MRI is now indispensable for diagnosing diseases and monitoring therapies. However, the ongoing discussion on gadolinium deposits in the brain has intensified the search for alternatives. Dr Daniel Paech of the German Cancer Research Centre in Heidelberg, Germany, discussed potential solutions to acquire high-quality images without contrast agents.
A research group detected the MRI contrast agent gadolinium in tap water and in cola soft drinks bought in restaurants of well-known fast-food franchises in cities across Germany. Gadolinium appears not to impose any health risk at the low concentrations observed. However, it is an indicator of the potential presence of other waste water-derived, possibly toxic xenobiotics.
