Keyword: liver

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LITMUS vs NAFLD

Towards better diagnosis and treatment of liver disease

A pioneering European research project designed to develop new diagnostic tests to assess patients with Non-Alcoholic Fatty Liver Disease (NAFLD) has expanded giving access to more patients. Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS) funded by the European Innovative Medicines Initiative 2 Joint undertaking, brings together clinical scientists from international…

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Subgroup detected

A new Diabetes classification?

The traditional classification of diabetes, mainly in type 1 and type 2 diabetes, has been challenged by studies from Scandinavia. In the current issue of The Lancet Diabetes & Endocrinology, researchers from DDZ together with colleagues from DZD and University of Lund published a cluster analysis of diabetes allowing for phenotyping into subgroups, which extended the findings by showing that…

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Chronic Liver Disease

Study confirms clinical benefit of ShearWave Elastography

SuperSonic Imagine announces that a multicenter retrospective study conducted in Europe and China, has confirmed the clinical utility of ShearWave Elastography in patients with chronic liver disease, the first results of which were presented at the International Liver Congress (ILC 2019). The objective of this study was to evaluate the diagnostic value of ShearWave Elastography (SWE) in the…

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Addiction

Ten percent of hospital inpatients are alcohol dependent

A review of evidence by researchers at King’s College London has found high levels of alcohol dependence among hospital inpatients. The researchers estimate one in five patients in the UK hospital system uses alcohol harmfully, and one in ten is alcohol dependent. Currently little is being done to screen routinely for alcohol dependence in hospitals, and services for patients with alcohol…

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NAFLD

Fatty liver disease: critical regulator discovered

Non-alcoholic fatty liver disease (NAFLD) is a condition where fat accumulates in the liver and has become the most common liver disease worldwide. While NAFLD shows few or no symptoms at initial stages, it is a potentially serious disease which can progress to an inflammatory state called steatohepatitis (NASH), which can lead to liver cirrhosis and cancer. Fatty liver disease can be managed by…

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Thrombocytes

Blocking platelets could prevent fatty liver disease and liver cancer

Non-alcoholic fatty liver disease is among the most common chronic hepatic disorders in Western industrial countries and the rate is also rapidly rising in newly industrialized countries. Experts estimate that about 30 to 40 percent of the population worldwide develop this liver condition. In the United States, this disease is well on the way to becoming the most frequent indication for liver…

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Hepatology

Fatty liver: especially dangerous during the holidays

More than 100 million Americans have potentially deadly fatty liver disease and most do not even know it. Overeating and drinking excessive amounts of alcohol this holiday season could put someone with the disease on the fast track to liver failure. “There are no symptoms associated with fatty liver disease and no pain, so most people never get checked or treated for it and, over time, if it is…

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Research

Unravelling the mystery of non-alcoholic fatty liver disease

Another piece in the puzzle that is non-alcoholic fatty liver disease has been solved by a University of Queensland researcher in a step towards developing treatments for a disease that affects about one in every five Australians. PhD student Laurence Britton has discovered a pivotal mechanism by which iron is able to make the liver more vulnerable to the injury and metabolic dysfunction that…

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New approach

Starving liver cancer

Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug. They describe their methods in a new paper published in Nature Communications. This research could accelerate the development of new treatments for liver cancer,…

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Oncology

Why liver cancer screening rates must improve

Patients with cirrhosis should be screened regularly for liver cancer, though few are – in part because busy physicians often don’t order the screening tests, said UT Southwestern oncologists. “The frequency of liver cancer is increasing rapidly in the U.S. and liver cancer-related mortality has nearly doubled over the past decade. The poor prognosis of the disease is largely driven by the…

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Diverse benefits

Experts present CEUS insights

In April 2016 CEUS received the USA’s FDA approval. This year‘s RSNA Samsung Symposium ‘Contrast-Enhanced Ultrasound (CEUS): Innovations and a Problem-Solving Tool in Clinical Practice’ provided an opportunity to take stock. For European Hospital, Professor André Clevert, Director of the Interdisciplinary Centre for Ultrasound at University Hospital Munich, Germany, describes the current…

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Local and elegant

Extending life with TIPS and TACE

Liver disease is widespread in Germany. It is, in fact, the most common cause of death in patients under the age of 40, with liver cirrhosis, which can develop into liver cancer, playing a major role here. These days, modern, comprehensive treatment concepts are unimaginable without interventional radiology, for liver cirrhosis as well as liver cancer. Prof. Dr. Christian Stroszczynski, Director…

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Diffuse liver diseases

The liver is a master of deception

Professor Dr Thomas Kröncke, Medical Director of Diagnostic and Interventional Radiology at Klinikum Augsburg, has been dealing with liver diseases for 17 years. Talking to European Hospital he explains which diseases the liver tends to mask and why fatty liver has become a public health issue.

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Radiology tech

LI-RADS promotes improved liver imaging techniques and reporting

From its earliest beginnings in 2006 to its most recent update this year, the Liver Imaging Reporting and Data System (LI-RADS) is helping radiologists deliver clearer and more consistent imaging reports to hepatologists and surgeons worldwide. "LI-RADS is the leading system for interpretation and reporting of liver imaging exams in adults with cirrhosis. It is also the first radiology…

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Split transplantation

One Liver. Two Saved Lives

A new study found that increased utilization of split liver transplantation could decrease the number of children who die awaiting liver transplantation without decreasing liver transplantation access for adult patients. “Among children listed for liver transplant in the United States, more than one in 10 infants and one in 20 older children die while waiting for a liver,” says Emily Perito,…

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Side effects

Do common acid reflux medications promote chronic liver disease?

Approximately 10 percent of the general population take a proton pump inhibitor (PPI) drug to block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux and gastroesophageal reflux disease. That percentage can be as much as seven times higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered…

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Biomarkers

Aiming for the earliest diagnosis of hepatocellular carcinoma

For almost three quarters of hepatocellular carcinoma (HCC) patients in Europe it is too late for curative treatment because the disease is often only diagnosed at a very advanced stage. Interviewed Professor Guido Gerken MD, Director of the Department for Gastroenterology and Hepatology at University Hospital Essen, about improved and timelier diagnostic capabilities that have already been…

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MRI & Liver

MRI leading the way in metabolic disease imaging

New MRI techniques are set to offer advances in the earlier detection of liver disease in patients. Radiologists are harnessing the potential of highly-targeted MRI, whilst exploring the imaging modality as a means of delivering non-invasive biomarkers, reducing the need for biopsy to measure treatment response.

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