Liver

News • Biomaterial research

MASLD: self-healing hydrogel as promising therapeutic approach

Researchers have developed a novel injectable self-healing hydrogel engineered to recapitulate the native hepatic microenvironment and restore liver function in Metabolic dysfunction-associated…

News • LITMUS studies

MASLD and MASH: Breakthrough in non-invasive liver testing

As first treatments for liver disease MASH enter clinical practice, demand for accurate diagnostics and monitoring options grows. Two new studies outline new ways for non-invasive liver testing.

News • Cardiovascular and cognitive changes

MASLD: Exploring the systemic impact of fatty liver disease

A new study links metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) to an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications.

News • Intrahepatic cholestasis of pregnancy

ICP: Large-scale study sheds light on pregnancy-related liver disease

A new study uncovers new factors associated with ICP, a pregnancy-related liver disease. The findings open up new avenues for research into maternal health and pregnancy-related liver diseases.

News • Transplant organ acceptance

“Immune priming” prevents donor liver rejection

A new technique to “prime” a patient's immune system before liver transplantation has proven itself in a first-in-human clinical trial to successfully prevent transplant rejection.

News • Position and completeness assessment

3D CT analysis benefits liver tumor ablation

By analyzing CT images with 3D software, researchers demonstrated that small liver tumors can be successfully treated using ablation. This could enable more confident use of ablation treatments.

News • Deep learning model

AI detects fatty liver disease with chest X-rays

A research group at Osaka Metropolitan University developed an AI model that can detect the presence of hepatic steatosis (fatty liver disease) from chest X-ray images.

News • HBV point-of-care identification

Hepatitis B: rapid diagnostic test to halt mother-to-child transmission

A new rapid diagnostic test can identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This could help prevent mother-to-child transmission during childbirth.

News • Outbreak response study

Hepatitis E vaccination: 2 out of 3 doses still effective in an epidemic

The vaccine to protect against Hepatitis E is given in a 3-dose regimen. However, in an epidemic setting, two doses have also proven effective, a new study shows.

News • Advances in precision medicine

MASLD: Research reveals two types of fatty liver disease

Metabolic-associated fatty liver disease has 2 types – a liver-specific type and a systemic type that affects other organs and tissues. This discovery could lead to better diagnosis and treatments.

News • Insights into bile production

Liver discovery could lead to better CVD treatments

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

News • Research aboard the International Space Station

How liver tissue from the ISS may transform tissue engineering

An “out-of-this-world” project has the potential to transform the future of tissue engineering and liver transplantation through research conducted aboard the International Space Station (ISS).

News • Hydrogel catalyst

Breaking down alcohol in the body: Researchers develop "detox gel"

Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.

News • Focus on protein GDF15

Newfound mechanism could improve efficiency of diabetes treatments

Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.

News • Promising study in mice

Exploring the potential of mRNA technology for rare diseases

Coronavirus vaccines have showcased the possibilities of messenger RNA (mRNA) technology. Now, a research team aims to put it to use against a rare inherited metabolic disorder.

News • Organ preservation

Perfusion machine takes time pressure off liver transplantation

A special perfusion machine preserves donor livers for an extended period of time without compromising organ quality. New Dutch research has confirmed the safety of the procedure for recipients.

News • Rapid, non-invasive test

Detecting chronic liver disease with targeted MRI

A research team has developed a nanoparticle-based contrast agent with the properties necessary to successfully use MRI for targeted diagnosis of liver fibrosis.

News • Study examines diagnostic quality

Ultrasound in obese patients: special probes improve imaging

High-BMI patients are a challenge for abdominal sonography. In a new study, researchers point out the benefits of special high-performance probes and their impact on image quality.

News • The role of arginine

Cancer research: Metabolite drives tumor development

University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.

News • 3D tissue culture platform

"Mini liver" shows promise for drug discovery

A European team of researchers have successfully developed a new, living organ model which could advance rapid testing of new or common drugs to treat diseases of the liver.

News • Neurodegeneration

The importance of the liver-brain axis in Alzheimer's disease

A research team from Barcelona studied the liver of Alzheimer's disease mice models, and demonstrated the importance of the liver-brain axis regarding the psychological symptoms of the disease.

News • Alternative to liver biopsy

Exploring the benefits of non-invasive MR Elastography in obese patients

Omar Darwish, PhD student at King's College London, is researching new approaches to 3D MRE sequences for measuring liver fibrosis and inflammation simultaneously in obese patients.

News • OrQA

Transplant organ quality assessment via AI: a promising approach

A pioneering new method to assess the quality of organs for donation has the potential to revolutionise the transplant system, saving lives and tens of millions of pounds.

News • Preventing EBV reactivation

Liver transplantation: Finding the "sweet spot" of immuno-suppression

Dutch physicians have developed a system to determine the right dose of immunosuppressive drugs for patients to receive a donor liver - to prevent the activation of the Epstein-Barr virus.

Article • Imaging advances

Liver disease assessment: AI may give CT the edge over MRI

To assess diffuse liver disease, MRI is currently the modality of choice. New developments in artificial intelligence (AI) could tip the scales in favour of CT imaging. At ECR 2022 in July, experts showed how AI technology enables CT to quantify liver fat as exquisitely as MRI.

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