DNA

News • DNA damage response

New insights into the DNA damage response

The study findings of a team from Julius-Maximilians-Universität Würzburg (JMU) in Bavaria, Germany help to broaden the conceptual view on the DNA damage response and to link it more closely with…

News • Research on DNA danage

Surprise finding on cancer cell death to impact therapies

Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.

News • Hybrid peptide-DNA nanostructures

Could artificial life forms be the medicine of the future?

What role should artificial life play in medicine? Researchers from Denmark and the US explore the potential of hybrid peptide-DNA nanostructures for diagnosing and treating diseases.

News • Real-time tumor profiling

AI tool decodes brain cancer’s genome during surgery

Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information that can guide treatment decisions.

News • Precision oncology

Genomic sequencing benefits only 5% of cancer patients

Genomic sequencing panels as part of personalised cancer treatment have been found to only benefit one in 20 patients they are currently used for, according to a study by CNIO.

News • MCED for 50+ cancer types

Multi-cancer blood test shows real promise

A trial of a new blood test for more than 50 types of cancer correctly revealed two out of every three cancers in more than 5,000 people who had visited their GP with suspected symptoms.

News • Independent genes

Cancer: Study sheds light on mysterious DNA rings

Tumors sometimes seem to take on a life of their own, with cancer genes “striking out” in ring shapes. An international research team has new insights into this phenomenon.

News • Genetics & Viruses

"Gene scissors" in human cells inhibit viral infections

Scientists at the University of Applied Sciences Krems (IMC Krems) show that CRISPR-Cas9 can also be used to inhibit viruses such as adenoviruses in cell cultures.

News • Model organisms evolved too far

How lab bacteria became 'estranged' from their real-life counterparts

A model organism used in laboratories for the past 100 years has evolved so extensively that it may no longer be fit for purpose, according to a new study on bacterial strain Escherichia coli K-12.

News • Personalised medicine

DNA-matching medication reduces side effects by 30%

According to an international group of researchers led by Leiden University Medical Center (LUMC), patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.

News • Researchers improve DNA cut-and-paste technique

Increasing safety for "gene scissors" CRISPR-Cas9

A new approach on the genetic tool CRISPR-Cas9 could reduce the risk of unwanted mutation, making it safer for use in humans, Dutch researchers have found.

News • Strand-seq

AI analysis of cancer mutations: a promising step towards new therapies

Combining single-cell data with a self-learning algorithm reveals how structural changes in chromosomes can trigger cancer. This could pave the way for personalized cancer treatments.

News • Promising reseach results

Using artificial DNA to kill cancer

Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way. The method showed promising results against various cancers in lab tests on mice.

News • CLL types with distinct biological and clinical features

Whole genome profiling reveals new leukaemia subgroups

A collaborative study has defined five new subgroups of the most common type of blood cancer, chronic lymphocytic leukaemia (CLL), and associated these with clinical outcomes.

News • Conference attendance

New lab systems for virology showcased at ESCV 2022

Dutch global DNA/RNA technology solutions provider MolGen B.V., participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, UK.

News • Genome instability

Gene editing via CRISPR/Cas9 can lead to cell toxicity

Researchers identify critical spots on the genome where gene editing could cause an unwanted response, and they provide recommendations for safer approaches.

News • Novel disease therapies

"Soft” CRISPR may offer fix for genetic defects

A new approach makes use of natural DNA repair machinery and provides a foundation for novel gene therapy strategies with the potential to cure a large spectrum of genetic diseases.

News • Not just for bitcoin

Blockchain can secure and store genomes

Blockchain is a digital technology that allows a secure and decentralized record of transactions. Now, researchers leveraged blockchain to give individuals control of their own genomes.

News • Nanochannels

Groundbreaking: Nanofluidic scattering microscopy

To develop new drugs, detailed knowledge about nature’s smallest biological building blocks is required. A new microscopy technique that allows proteins, DNA and other tiny biological particles to be studied in their natural state.

News • Genetics research

Chromosomes: How the 'extra X factor' is putting men at risk

Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis.

Article • Clinical computational tools

Managing cancer more effectively

Computational approaches are being applied on enormous amounts of data from sequencing technologies to develop tools to help clinicians manage cancer more effectively.

MolGen introduces high quality DNA/RNA extraction kits for efficient high throughput testing

SARS-CoV-2 has heavily impacted global society with high pressure on public health and economics. MolGen is proud to assist in relieving some of the pressure and support the testing framework.

News • From decades to days

Single test for over 50 genetic diseases cuts diagnosis

A DNA test has been shown to identify a range of hard-to-diagnose neurological and neuromuscular genetic diseases quicker and more-accurately than existing tests.

News • Pathogen analysis

Unlocking epidemic prevention with affordable genome sequencing

A worldwide consortium aims to equip researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequencing large collections of bacterial pathogens.

Providing innovative molecular workflows to empower future diagnostics

Founded in 2018 as a DNA extraction chemistry company, Dutch company MolGen entered the market operating within the agricultural sector. At first, the company’s founders, Maarten de Groot, Wim van Haeringen and Niels Kruize, focused solely on this one industry, mainly developing and marketing advanced bulk chemistry kits for DNA/RNA extraction. These testing products and solutions successfully…

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