DNA

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News • Impact on healthy tissues uncovered

Study explores cost of childhood chemotherapy

For many childhood cancers, chemotherapy is the only treatment option. A study explores the trade-off between life-saving treatment at a young age, and delayed side effects unfolding over a lifetime.

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News • Mutational process analysis

Scientists explore DNA damage in prostate cancer for better predictions

New research offers an explanation for why many men live with prostate cancer for decades while for others it turns lethal: The work identifies which processes cause DNA damage in most of the cancers.

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News • Research explores key role of chromatin

Kabuki syndrome: new insights offer hope for therapies

New research has identified a previously unknown mechanism of Kabuki syndrome, a rare genetic disorder. The discovery could open new therapeutic perspectives.

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News • Pediatric oncology

"Genomic fingerprints" left by chemotherapy could point to more precise cancer treatments

Chemotherapy of many childhood cancers leaves specific traces in the DNA, a new study finds. These changes could help clinicians spot treatment resistance earlier, before cancer returns or spreads.

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News • Exploring the landscape of tumour methylation

Parsing the pathology of prostate cancer

Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.

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News • BayesCNA

New blood analysis method to improve cancer care

Blood tests show promise for detecting and monitoring cancer. A new method makes it possible to analyse samples containing as little as 5% cancer DNA, compared with the 15–20% required today.

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Article • Personalised medicine

Gene-editing technologies: from lab to patient

Gene-editing technologies show great promise for medical treatments and research, with the potential to cure thousands of genetic diseases. At the 2025 World Medical Innovation Forum in Boston, leading experts explored the possibilities and challenges of these rapidly advancing tools. The case of Baby KJ Muldoon – an infant treated with a personalised CRISPR therapy developed in just seven…

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