Metabolism

News • Cardiovascular and cognitive changes

MASLD: Exploring the systemic impact of fatty liver disease

A new study links metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) to an elevated risk of cardiovascular disease, cognitive decline, and other metabolic complications.

News • Lung cancer insights

Brain metabolism predicts survival in advanced NSCLC patients

Low brain metabolism as measured from 18F-FDG PET/CT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research.

News • Commensal dysbiosis

Study links bile acid buildup to breast cancer metastasis

A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new research reveals. The findings could open the door to new ways to prevent cancer metastasis.

News • Impact beyond weight loss

Whole-body PET/CT reveals metabolic changes after bariatric surgery

A novel PET imaging framework reveals that bariatric surgery impacts not only body weight, but also the metabolic function of organs. These insights could support more precise treatment monitoring.

News • Metabolic health

Obesity helps breast cancer become invasive

Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.

News • Impact on type 2 diabetes

Gut microbiota shape metabolic health after bariatric surgery

Changes in gut microbiota after bariatric surgery are strongly linked to altered metabolic health and sustained improvement in type 2 diabetes, according to a new study.

News • Microscopy

New microscopy method maps lipids without labels

A new microscopy method reads lipids' natural spectral fingerprints using mid-infrared light and ultrasound – no fluorescent labels needed, less stress for living cells.

News • AI detects unseen connection

Insulin resistance identified as risk factor for cancer

Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.

News • Study finds faster regain than ending diet programmes

GLP-1 discontinuation: weight-loss drugs work – until you stop

Drawbacks of GLP-1 discontinuation: People tend to regain weight rapidly after stopping weight-loss drugs - and faster than after ending behavioural weight loss programmes - according to new research.

Sophie Nicklaus

Driving sustainable, health-promoting food systems

Sophie Nicklaus has been officially appointed Scientific Director of Food & Health for a four‑year term, by Philippe Mauguin Chair and CEO of INRAE, following consultation with its Board of Directors on 13 October.

News • Melancholic vs. fatigued

Depression subtypes linked to different cardiometabolic diseases

It is known that depression is linked to increased incidence of metabolic diseases; now scientists have discovered that different types of depression are linked to different cardiometabolic diseases.

News • Focus on adipose tissue metabolism

Endometrial cancer: visceral fat may drive aggressiveness

Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.

News • Endocrinology

European study establishes leptin reference values across age groups

International research led by Leipzig and Ulm universities creates first standardized leptin reference values for all ages and weight classes, advancing personalized medicine

News • Microbiome

Fatty acids fuel cancer-promoting gut bacteria

TU München researchers discover how chronic cellular stress changes gut microbiome composition, promoting cancer development through altered lipid metabolism.

News • Gut function and microbiome analysis

MRI reveals impact of gluten free diet on people with celiac disease

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with celiac disease, which could be the first step towards new treatments.

News • Single-cell metabolic profiling

Mass-spec and IMC give deep insights into tumors

By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.

News • When red means bad (for the heart)

Nutri-Score hints at foods that increase CVD risk

The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.

News • Diabetes, hypertension, and more

AI reads facial temperature for early diagnosis of metabolic diseases

Measuring temperatures in different face regions could be used to earlier detect chronic illnesses, such as diabetes and hypertension. Researchers now show the potential of an AI-based approach.

News • Disturbed lipid metabolism

Charcot-Marie-Tooth: Researchers uncover impact of genetic cause

Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic interventions.

News • Study analyses admissions in Spain

Summer heat sends more people into hospital, study finds

Metabolic disorders, renal failure, UTIs, sepsis, poisoning: The higher temperatures climb in summer, the more people are hospitalized, a study shows - with some groups being more at risk than others.

News • Hydrogel catalyst

Breaking down alcohol in the body: Researchers develop "detox gel"

Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.

News • Cortisol sampling from blood

Paving the way for better diagnosis and treatment of endocrine diseases

A team of researchers has discovered a new method of measuring levels of cortisol directly from a blood sample - a significant step forward in diagnosis and treatment of a wide range of diseases.

News • Focus on protein GDF15

Newfound mechanism could improve efficiency of diabetes treatments

Research reveals how a new mechanism could improve the efficiency of current treatments for diabetes. This may open up new ways of approaching metabolic diseases that are a global health problem.

News • Excessive fluid consumption

Thirsty all the time: harmless habit or hormonal disorder?

Drinking more than three liters of fluid per day may be a harmless habit – or a warning sign for a rare hormone deficiency. Swiss researchers investigated tests to differentiate between the two.

News • The role of arginine

Cancer research: Metabolite drives tumor development

University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.

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