Drinking more than three liters of fluid per day may be a harmless habit – or a warning sign for a rare hormone deficiency. Swiss researchers investigated tests to differentiate between the two.
University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.
A new imaging method devised by German researchers offers a fast and cost-effective way to observe abnormal metabolic processes live in the MRI scanner.
Ongoing research at the University of Roehampton, UK has identified the upper critical temperature (UCT) for humans - and why our bodies cannot handle more heat.
US researchers have developed a way to use MRI scanning to map body cell metabolism, opening up new possibilities for detecting cancers and revealing if a tumor is responding to treatment.
Exposure to a mixture of chemicals called PFAS - also known as 'forever chemicals' - leads to alterations in biological processes associated with a broad range of diseases, a new study finds.
Swiss researchers developed a new MRI method to visualise metabolic processes in the body. Their objective is to improve the future diagnosis and treatment of heart disease.
Overweight increases the risk of an imbalance in sugar metabolism and even diabetes – but the opposite is also true: insulin production deficits contribute to overweight, a new study shows.
Older people with hypothyroidism, also called underactive thyroid, may be at increased risk of developing dementia.
Scientists have taken the first step to creating the next generation of wearable health monitors, which could monitor the body’s health by detecting the gases released from a person’s skin.
Hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly.
Scientists have found that fat can help the pancreas adapt to excess sugar, thereby slowing the onset of diabetes.
Hyperpolarized MRI is a recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz (JGU) and the Helmholtz Institute Mainz (HIM) have now unveiled a new technique for observing metabolic processes in the body. Their singlet-contrast MRI method employs easily-produced parahydrogen to track biochemical processes in…
Tumour metabolism can be imaged with MRI as a technique to help determine cancer aggressiveness and response to therapy. The work by a UK-based group, on probing cancer metabolism non-invasively with clinical hyperpolarised carbon-13 MRI, can detect metabolic changes in the tumour. As metabolic changes occur much earlier than change in tumour size, this could have implications for quicker…
Our brains are non-stop consumers. A labyrinth of blood vessels, stacked end-to-end comparable in length to the distance from San Diego to Berkeley, ensures a continuous flow of oxygen and sugar to keep our brains functioning at peak levels. But how does this intricate system ensure that more active parts of the brain receive enough nourishment versus less demanding areas? That’s a century-old…
Bacteria have many ways to evade the antibiotics that we use against them. Each year, at least 2.8 million people in the United States develop an antibiotic-resistant infection, and more than 35,000 people die from such infections, according to the U.S. Centers for Disease Control. Most of the mutations known to confer resistance occur in the genes targeted by a particular antibiotic. Other…
Mass spectrometry-based metabolomics has emerged as a powerful tool to help study chemical ecology. Recent advances in the technique make it possible to study microbial interactions from complex communities. Laia Castaño-Espriu outlined the role and benefits of MS in this context in her presentation ‘Analysis of microbial ecology by mass spectrometry-based metabolomics techniques’, at the…
A diet high in sugar increases the likelihood of developing pancreatic cancer in some people and can also drive the aggressive growth of tumours, a new study finds. During this study, researchers from the University of Surrey, VIB-KU Leuven, Belgium and the Babraham Institute in Cambridge, sought to understand the impact of diet on the development and progression of pancreatic cancer. This rare…
Scientists at Sanford Burnham Prebys have found a new way to kill pancreatic cancer cells by disrupting their pH equilibrium. The study, published in Cancer Discovery, reports how depleting an ion transport protein lowers the pH to a point that compromises pancreatic cancer cell growth. Pancreatic cancer cells—like all cancer cells—have a constant need for energy to support their growth and…
