Metabolism

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News • Single-cell metabolic profiling

Mass-spec and IMC give deep insights into tumors

By combining mass spectrometry and mass cytometry imaging techniques, researchers can now dive deeper into tumors and map the metabolism of individual cells in tumor tissue.

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News • When red means bad (for the heart)

Nutri-Score hints at foods that increase CVD risk

The Nutri-Score is designed to provide consumers with information on nutritional quality. New research reveals that the ratings also correspond with the cardiovascular health impact of the products.

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News • Diabetes, hypertension, and more

AI reads facial temperature for early diagnosis of metabolic diseases

Measuring temperatures in different face regions could be used to earlier detect chronic illnesses, such as diabetes and hypertension. Researchers now show the potential of an AI-based approach.

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News • Disturbed lipid metabolism

Charcot-Marie-Tooth: Researchers uncover impact of genetic cause

Charcot-Marie-Tooth disease is often characterized by a duplication of the PMP22 gene. New research assessing the impact on developing Schwann cells could point the way ahead to future therapeutic…

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News • Study analyses admissions in Spain

Summer heat sends more people into hospital, study finds

Metabolic disorders, renal failure, UTIs, sepsis, poisoning: The higher temperatures climb in summer, the more people are hospitalized, a study shows - with some groups being more at risk than others.

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News • Hydrogel catalyst

Breaking down alcohol in the body: Researchers develop "detox gel"

Researchers have developed a gel that breaks down alcohol in the GI tract without harming the body. In the future, people who take the gel could reduce the harmful and intoxicating effects of alcohol.

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News • Singlet contrast imaging

Hyperpolarized MRI enables real-time view on metabolic processes

Hyperpolarized MRI is a recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz (JGU) and the Helmholtz Institute Mainz (HIM) have now unveiled a new technique for observing metabolic processes in the body. Their singlet-contrast MRI method employs easily-produced parahydrogen to track biochemical processes in…

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Article • Imaging tumour metabolism

Hyperpolarised MRI boosts cancer diagnosis

Tumour metabolism can be imaged with MRI as a technique to help determine cancer aggressiveness and response to therapy. The work by a UK-based group, on probing cancer metabolism non-invasively with clinical hyperpolarised carbon-13 MRI, can detect metabolic changes in the tumour. As metabolic changes occur much earlier than change in tumour size, this could have implications for quicker…

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News • Neuro-map reveals nourishment mechanisms

Food for thought: How our brain keeps its supply up

Our brains are non-stop consumers. A labyrinth of blood vessels, stacked end-to-end comparable in length to the distance from San Diego to Berkeley, ensures a continuous flow of oxygen and sugar to keep our brains functioning at peak levels. But how does this intricate system ensure that more active parts of the brain receive enough nourishment versus less demanding areas? That’s a century-old…

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News • Infection research

Mutations help bacteria resist antibiotic treatment

Bacteria have many ways to evade the antibiotics that we use against them. Each year, at least 2.8 million people in the United States develop an antibiotic-resistant infection, and more than 35,000 people die from such infections, according to the U.S. Centers for Disease Control. Most of the mutations known to confer resistance occur in the genes targeted by a particular antibiotic. Other…

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Article • Mass spectrometry-based metabolomics

A new technique to understand metabolic pathways

Mass spectrometry-based metabolomics has emerged as a powerful tool to help study chemical ecology. Recent advances in the technique make it possible to study microbial interactions from complex communities. Laia Castaño-Espriu outlined the role and benefits of MS in this context in her presentation ‘Analysis of microbial ecology by mass spectrometry-based metabolomics techniques’, at the…

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