For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked to an increased risk for failure and…
The consequences of organ rejection in transplant patients can be devastating. Professor A. Vathsala, co-director of the National University Centre for Organ Transplantation at the National University Hospital (NUH) and professor of medicine, says that between 30 percent to 40 percent of kidney transplants are lost over time to rejection. She and Associate Professor Paul MacAry of the Department…
‘Do we want transplant medicine? And if yes, what are we prepared to change in public policy, society and medicine?’ This question characterises the current situation within this medical discipline. Since the 2011 transplant scandal, there has been a steady decline in organ donations according to the German Foundation for Organ Donation (DSO). Although there were some 1,200 transplant donors…
New research indicates that many kidneys obtained for transplantation from deceased donors are not being used because of biopsy findings despite their unreliability and reproducibility. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN) and will be published at ASN Kidney Week 2018, may suggest an urgent need to re-examine the…
A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells. Such a practice could help doctors identify patients at high risk of disease recurrence early after a transplant and help guide treatment decisions.
A new study found that increased utilization of split liver transplantation could decrease the number of children who die awaiting liver transplantation without decreasing liver transplantation access for adult patients. “Among children listed for liver transplant in the United States, more than one in 10 infants and one in 20 older children die while waiting for a liver,” says Emily Perito,…
A new study indicates that many donated organs that are discarded might be suitable for transplantation if certain steps are taken to limit damage following donation. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN). In most cases in the United States, transplant organs come from donors following brain death, in which all the functions of the…
Researchers in Germany have demonstrated that hematopoietic stem cell (HSC) transplants can be improved by treatments that temporarily prevent the stem cells from dying.
Whilst Spain has announced a new record for organ donations the number in Germany is stabilising at a ‘low level’. The good news? The number did not fall any further following scandals surrounding the manipulation in the allocation of donor organs.
The results of a new study suggest that high discard rates among donated kidneys could be avoided in the future. Researchers say that even kidneys with poor biopsy results may be more efficient in prolonging patients' lifespans than other treatments.
Surgeons at Johns Hopkins Medicine report that their first series of a minimally invasive procedure to treat chronic pancreas disease, known as severe pancreatitis, resulted in shorter hospital stays, less need for opioids and fewer complications, compared with standard surgical approaches.
Certain white blood cells play an important role in bringing a harmful virus under control after kidney transplantations. The results of a research group at the Department of Biomedicine at the University of Basel and University Hospital Basel could contribute to improving control of immunosuppression, avoiding transplant rejection and developing relevant vaccines.
Approximately 30,000 organ transplants occur in the United States each year. However, between 20 and 50 percent—depending on the organ type—of the transplanted organs fail within five years, most often because the recipient’s immune system attacks, or “rejects,” the donated organ.
A new method which doubles the usual time donor lungs can remain outside the body can benefit patients, staff and allow retrieval of donor lungs across greater geographical areas, says a study published in The Lancet Respiratory Medicine.
Mechanical ventilation and subspecialisation are key aspects of modern anaesthesia and critical care practice according to Dr Javier Garcia Fernandez, Head of Critical Care and Anaesthesiology at University Hospital Puerta de Hierro in Madrid.
Using the results from a computerized mathematical model, Johns Hopkins researchers investigated whether they could improve heart and lung transplantation procedures by transferring patients from low-volume to high-volume transplant centers.
A small report in the press prompted examination of a much neglected topic. The report read ‘Heart Centre at University Hospital no longer carries out transplants’, and referred to the University Hospital Frankfurt, one of the 22 Heart Centres that perform these transplantations.
Scientists at the Institute of Molecular Biotechnology (IMBA) and the Max F. Perutz Laboratories (MFPL) in Vienna have discovered a new way to turn the immune system’s weapons against fungal invaders. This knowledge could lead to the development of new and improved anti-fungal treatments.
With 4,360 transplant operations from 1,682 donations in 2014, Spain broke the country’s own record and confirmed its place as the world leader in organ donations, a position it has held for the past 24 years.
Following a heart attack or other heart trauma, the heart is unable to replace its dead cells. Patients are often left with little option other than heart transplants, which are rarely available, or more recently cell therapies that transplant heart cells into the patient's heart.
A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre (CRCHUM.)
Scar-free facial reconstruction is now a reality. A team led by Daniel Borsuk, a doctor at Hôpital Maisonneuve-Rosemont and a professor at the University of Montreal, recently conducted the very first such procedure in the history of plastic surgery in Canada.
A new 3D computer modeling system may significantly improve a surgeon's ability to select the best sized donor heart for children receiving heart transplants, according to research presented at the American Heart Association's Scientific Sessions 2015.
Surgeons at The Children’s Hospital of Philadelphia (CHOP) joined with colleagues from Penn Medicine recently to complete the world’s first bilateral hand transplant on a child. Earlier this month, the surgical team successfully transplanted donor hands and forearms onto eight-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney…
‘It’s like a new lease on life,’ says Wolfgang R, ‘I can feel the difference between grass and concrete again.’ Eight years ago the Austrian teacher‘s lower leg had to be amputated following thrombosis. Today, he is the first leg amputee, worldwide, to sport a sensory-enhanced prosthesis. ‘For the wearer the prosthesis is not a numb object, but a part of the body,’ says Dr Hubert…