Keyword: neurology

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Smart algorithm

Automated analysis of whole brain vasculature

Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Research Centre for Environmental Health and the Technical University of Munich (TUM) have come up with a technique for visualising the structures of all the brain's blood vessels – right down to the finest capillaries – including any pathological changes. So…

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Assessment of brain tumour treatment response

Developing AI algorithms for earlier glioblastoma detection

Novel advanced imaging biomarkers are being developed in a series of studies at several UK centres that may lead to the earlier assessment of treatment response to glioblastoma (GBM) and a better survival rate. Through a number of clinical trials – and the application of artificial intelligence (AI) to retrospective data sets – the aim is to highlight approaches that will enable clinicians to…

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Finding treatment for Parkinson's disease

Synthetic neurons could take brain research to the next level

The body can recover from many things, but the damage caused by Parkinson’s disease isn’t one of them. No cure exists for Parkinson’s, which 1 million people in the U.S. are expected to be living with by 2020. But an outright cure isn’t the primary objective of research by Chongli Yuan, a Purdue University chemical engineering professor and leader of Purdue’s section of a…

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Dementia diagnostics

Lack of sleep might throw off Alzheimer’s test

A preliminary study has found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer’s disease, in their blood than when they had a full, uninterrupted night of rest. The study is published in the January 8, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology. Tau is a protein found in…

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NICO Myriad NOVUS resection tool

Xenon lighting for neurosurgery

NICO Corporation, a company based in Indianapolis, Indiana, is releasing its new Myriad Novus resection tool. The FDA cleared product combines xenon illumination with NICO’s proven Myriad neural tissue removal technology. Xenon lights reproduce the visible spectrum of daylight much better than most other bulbs – although LED contenders are now available – and so are often the optimal choice…

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Promising preclinical study results

Epilepsy: Gene therapy shows long-term suppression of seizures

Teams of researchers from Charité – Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having been shown to be effective in an animal model, the new method will now be optimized for clinical use.…

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Inherited neuromuscular disease HSP

Genetic cause for hereditary spastic paraplegia identified

Scientists at St George’s, University of London, in collaboration with researchers from Germany, the USA, Tunisia and Iran have identified a new gene associated with the neuromuscular disorder, hereditary spastic paraplegia (HSP). The study, published in Nature Communications, also highlights a potential mechanism for the disease, which is already being targeted in drug trials for Alzheimer’s…

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Rehabilitation

Hope for patients in vegetative and minimally conscious states

Non-invasive brain stimulation is to be trialed for the first time alongside advanced brain imaging techniques in patients who are minimally conscious or in a vegetative state. The study builds on promising results from the Centre for Human Brain Health at the University of Birmingham which suggested that non-invasive brain stimulation can improve the success of rehabilitation for non-responsive…

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Dangerous fever

Febrile convulsions: an early indicator for epilepsy in children?

Children who suffer repeated febrile convulsions have an increased risk of developing epilepsy and psychiatric disorders such as schizophrenia and depression later in life. This is shown by a comprehensive register-based study from Aarhus University. The risk of febrile convulsions increases with the child’s fever, and approximately four per cent of Danish children suffer from febrile…

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Neurology

Overcoming the blood-brain-barrier: Delivering therapeutics to brain

For the first time, scientists have found a way that can effectively transport medication into the brain - which could lead to improved treatments for neurological and neurodegenerative diseases. In a study, scientists from Newcastle University have led an international team in a major breakthrough in unlocking the secrets of how medications can infiltrate the brain.

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Interneurons

Epilepsy: When the function of "brake cells" is disrupted

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which researchers from Lisbon were also involved, points in this direction. The results are…

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Brewing up brain benefits

Drinking tea improves brain health

A recent study led by Assistant Professor Feng Lei from the National University of Singapore (NUS) Yong Loo Lin School of Medicine’s Department of Psychological Medicine revealed that regular tea drinkers have better organised brain regions – and this is associated with healthy cognitive function – compared to non-tea drinkers. The research team made this discovery after examining…

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Stopping the seizures

Epilepsy surgery: the earlier the better, study shows

A person with drug resistant epilepsy who gets an early surgical intervention has a better chance of becoming seizure free. This is shown in a systematic review and meta-analysis in which Sahlgrenska Academy researchers, in collaboration with the Swedish Council for Assessment of Health Technology and Social Services (SBU), analysed results from a range of previous studies. They concluded that…

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Macular degeneration as a biomarker

Eye scan shows diseases at an early stage

More and more people aged 50 and over are suffering from age-related vision disorders. According to the World Health Organization, in four out of five cases they could be avoided if they were diagnosed at an early stage. A European team of scientists, including the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, has now researched a new method that will enable doctors to better…

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Nanotechnology

Tiny diamonds in the brain

The recording of images of the human brain and its therapy in neurodegenerative diseases is still a major challenge in current medical research. The blood-brain barrier, a filter system of the body between the blood system and the central nervous system, constrains the supply of drugs or contrast media that would allow therapy and image acquisition. Scientists at the Max Planck Institute for…

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Improved motion range

Brace yourselves: Robotic neck support for ALS patients

A novel neck brace, which supports the neck during its natural motion, was designed by Columbia engineers. This is the first device shown to dramatically assist patients suffering from Amyotrophic Lateral Sclerosis (ALS) in holding their heads and actively supporting them during range of motion. This advance would result in improved quality of life for patients, not only in improving eye contact…

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Neurology

Key proteins for the repair of nerve fibers

Neurons of the central nervous system (CNS) shut down their ability to grow when they no longer need it; this is commonly accepted knowledge. This occurs normally after they have found their target cells and established synapses. However, recent findings show that old nerve cells have the potential to regrow and to repair damage similar to young neurons. The underlying mechanisms for this…

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Double danger

MS patients at a greater risk of cancer, new study suggests

New results of a 65-year follow-up study of nearly 7,000 Norwegian patients with Multiple Sclerosis (MS) suggest that patients may have a greater overall risk of developing cancer than the general population, with an especially high risk of cancer in respiratory organs, urinary organs and the central nervous system. Presented at the 5th European Academy of Neurology (EAN) Congress in Oslo,…

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Psychiatry

Leonardo da Vinci: pure genius or ADHD?

Professor Marco Catani suggests the best explanation for Leonardo da Vinci's inability to finish his works is that the great artist may have had Attention Deficit and Hyperactivity Disorder. Leonardo da Vinci produced some of the world’s most iconic art, but historical accounts of his work practices and behaviour show that he struggled to complete projects. Drawing on these accounts, Professor…

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