From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.
The key challenges and opportunities surrounding High-Content Screening have been outlined in a presentation to leading scientists and technologists at a major lab conference. Speaking at the recent SLASEurope 2019 event in Barcelona, Professor Matthias Nees from the Institute of Biomedicine in the Department of Biology at the University of Turku, Finland, outlined the potential of High-Content…
Artificial Intelligence (AI) is destined for a significant role in assessing histology data but the key to developing the necessary algorithms lies in data quality – rather than the quantity, according to Professor Jens Rittscher. He also warns that we are some distance from seeing AI replacing human pathologists in this scenario, primarily because presently the risks of automated…
If a health sector employee falls ill with a bloodborne disease, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with a needlestick injury (NSI), is among the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Among the most effective ways to…
At the 71st AACC Annual Scientific Meeting & Clinical Lab Expo, Siemens Healthineers features in Booth #1039 its innovative IT solutions to combat the laboratory’s staffing challenges, limited budgets, and the increasing complexity in sample management and testing. “We will be demonstrating the power of our broad IT offerings and how the data they deliver, and artificial intelligence, can…
Beckman Coulter Life Sciences launched the online DURA Innovations calculator tool, a powerful cost benefit analysis resource to accompany its latest Cost Benefit Calculator Handbook. The free online tool enables laboratories to quantify the value of converting to a standardized flow cytometry workflow using the company’s dry reagent technology. The new calculator enables customers using liquid…
Thermo Fisher Scientific Inc. is showcasing its latest instruments, assays and software for improving speed, accuracy and usability across clinical and research labs during the 71st American Association for Clinical Chemistry Annual Scientific Meeting and Clinical Laboratory Exposition (AACC 2019). Thermo Fisher is exhibiting in booth 2110 at the Anaheim Convention Center, Anaheim, Calif., August…
Acoustic Mist Ionization Mass Spectrometry (AMI-MS) has played a pivotal role in the evolution of high-throughput screening (HTS) and now steps are being taken to advance this field to other potential applications. AstraZeneca has been an important player in this area, having already run more than 10 full collection HTS campaigns against a range of enzyme target types, and the company is now…
Since the microprocessor entered the medical laboratory we have watched how those responsible also have been confronted with the errors in the software supplied with it. Obviously, such errors are to be avoided or found and corrected before use. Nonetheless complete error-free software remains a dream. ISO 15189:2012 makes it obligatory for the manufacturer to identify errors in the form of…
We talked to Dr Annika Blank, Consultant and Lean green belt, about eight-year experience with the concept and optimisation of processes, the implementation of digital pathology and a voice recognition system for patient management. "The biggest and most cost intensive step taken to optimise workflows was the refurbishment of our laboratory, which was completed in 2016. This allowed us to…
Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. A research team from University Hospital Zurich and the University of Oxford have now developed a method to predict the molecular classification of colorectal cancer from digital pathology slides.
Many countries across the world are challenged with a rising number of incidences of multi-drug resistant (MDR) organisms infecting the population, and for several years, a clear pattern of increased resistance has emerged in southern and eastern European countries. For example, in countries such as Italy, a reduced number of therapeutic options remain available for highly pathogenic infections,…
Oncimmune Holdings plc, a leading global immunodiagnostics group, announces it has entered into an exclusive partnership agreement which it believes will unlock the full potential of EarlyCDT Lung in the United States, bringing this lung cancer test to more patients as a result. This agreement with Biodesix, Inc., a leading lung cancer diagnostic solutions company, encompasses both the…
The majority of women who undergo surgery for suspected ovarian cancer do not have cancer. A novel blood test developed by researchers at Uppsala University and the Sahlgrenska Academy, University of Gothenburg, now offers the possibility of more precise diagnostics without the need for surgery. This could lead to a reduction in unnecessary surgery and to earlier detection and treatment for…
As reporting workload for pathology departments continues to rise rapidly, artificial Intelligence solutions are set to play an increasing role in daily practice. In many pathology departments the annual number of cases has risen by around 2-4% but the slides produced has doubled in the last decade. Histopathologist Professor David Snead identified this phenomenon within his own centre in the…
A new deep learning algorithm, which demonstrates the potential of artificial Intelligence (AI) to support pathologists, has been developed for PD-L1 scoring in tumour cells and immune cells in urothelial carcinoma samples. Speaking at the Digital Pathology and Artificial Intelligence Congress in London last December, Dr Michel Vandenberghe, from AstraZeneca, outlined how PD-L1 expression level…
With a case fatality rate of 35 percent, a Middle East respiratory syndrome-related coronavirus (MERS-CoV) infection – also called camel flu – is a dangerous disease. About seven years ago, when the virus was first isolated, mortality was close to 100 percent since only severe infections that led to the patient being in intensive care were recorded. Today the environment of each victim is…
Olympus has broken down barriers to imaging quality with the launch of its next-generation objectives. The breakthrough polishing technique enables the company to produce ultra-thin lenses that overcome the traditional trade-off between numerical aperture (NA), flatness and chromatic correction – enabling all three parameters to be significantly improved. Olympus has harnessed this proprietary…
Oxford Gene Technology (OGT), A Sysmex Group Company, has celebrated the opening of its new facility in Cambridge, UK. The opening ceremony, which took place at the company’s new premises on the prestigious Cambridge Science Park, was attended by the Department for International Trade (DIT) and local media as well as top-level representatives from OGT and its parent company, Sysmex Corporation.…
A new benchtop automated reading and incubation system is now available in Europe for antimicrobial susceptibility testing (AST). The new instrument provides microbiology laboratories with the accurate MIC results that clinicians need to confidently select an effective antibiotic for critically-ill patients while safeguarding future patient care through more successful antimicrobial stewardship.…
Bring your application into the digital world and combine the new Olympus EP50 camera with our wide range of microscopes. Add the accesoires you need and choose the kit that fits your requirements. The Olympus EP50 camera makes digital imaging of microscopy samples a fast and engaging experience and is ready to use in seconds. The EP50 camera adds sophisticated digital features to any microscope…
Stem cells are surrounded and protected by the stem-cell niche – the microenvironment – of the tissue in which they are found. Researchers at Karolinska Institutet have mapped the stem-cell niche in the bone marrow of mice and studied how it is influenced by developing leukemia. Their results, which are published in the journal Cell, show that the bone-marrow microenvironment is more complex…
A recent study can help governments understand which diagnostic laboratory tests are most important when developing universal health coverage systems. Researchers from five countries found that diagnostic laboratory tests are used similarly around the world, even though the institutions they studied differed in terms of poverty levels, health systems and prevalence of disease. “Even though…
The new Yumizen H2500 is a high-end haematology analyser with CBC, 8-DIFF, NRBC, reticulocytes, optical platelets and Body Fluids (CE). Full automation for demanding haematology diagnostics, can be integrated into the Horiba T6000 conveyor belt solution, with the option of a fully-automatic blood smear and staining unit (Yumizen SPS).
Since the firm was created almost 30 years ago, Roland Steger, the founder and CEO of Axon Lab AG, always regarded it as important for it to help resolve social challenges as well as achieving commercial success: “It was always clear to me that a purely economic, profit-focused business strategy is not sufficient in the long term. A spirit of partnership and cooperation, supporting projects…
Of course every lab needs a spectrophotometer to measure its DNA, RNA or protein concentrations. In most cases, this is a small and easy-to-use instrument. Normally you pipette approximately 1 µl of your liquid onto a pedestal, close the lid to cover your drop of liquid and, after pressing the measuring button, you will know the concentration of your sample. Since the procedure is so simple and…
