Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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News • Increased infection risk

AMR: drug resistant bacteria can travel from gut to lung

A new Oxford University study provides the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs, increasing the risk of deadly infections.

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Article • Early detection approach

Multi-cancer blood tests could shake up screening

New tests can identify over 50 types of cancer and boost detection of traditionally elusive cancers from tumour DNA in blood, researchers showed at the ESMO congress in September. These multi-cancer…

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Sponsored • Diagnostics Alliance against SARS-CoV-2

The Global Alliance for Diagnostics Sets Next-Generation POC Molecular Testing Collaboration

The coronavirus pandemic is a huge challenge for global public health and welfare. Decentralized, affordable POC MDx platforms would allow more effective control of SARS-CoV-2 and other infections.

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Sponsored • TissueTek Genie System

Advanced staining can be beautifully simple when we standardise it

Imagine, one single standardising solution, enabling uncompromisingly fast results and providing you with the exact same predictable turnaround time.

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Article • Detecting several different diseases

Multiplex diagnostics: next-generation techniques for new challenges

With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.

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News • Immune systems timulation

Using senescent cells as anti-cancer vaccines

Researchers from Barcelona report that vaccination with senescent cells shows promise in experimental models of melanoma and pancreatic cancer.

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Article • Tissue-engineered glioblastoma model

3D brain tumour in a dish to personalize cancer treatment

It is the size of a common pencil eraser, but it could have a huge impact on the therapy of glioblastoma: Scientists in Virginia have developed a novel 3D tissue-engineered model of the brain tumour microenvironment, which can be used to assess how the glioma cell invades healthy tissue, proliferates, and reacts to chemotherapy drugs.

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News • Deadly heart inflammation

Hope for first blood test to detect myocarditis

The first blood test to diagnose inflammation of the heart muscle (myocarditis) could be in use in as little as a year, following the discovery of a molecular signal in the blood.

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Automation

Tissue-Tek Genie Advanced Staining System – Sakura Finetek

The Tissue-Tek Genie Advanced Staining System is the first and only fully automated, true random access stainer for immunohistochemistry (IHC) and in situ hybridisation (ISH); allowing any IHC or ISH…

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Article • Regulatory challenges for AI-based diagnostics

Further IVDR changes: a step in the right direction, but…

New changes made to the timetable for the In vitro Diagnostic Medical Device Regulation (IVDR) across Europe could have a significant impact on manufacturers and users, an expert points out. While…

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Mass Spectrometry

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Nova Biomedical – StatSensor Creatinine

Clinical Chemistry

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Beckman Coulter – DxM Autoplak Automation

Automation

Beckman Coulter – DxM Autoplak Automation

Beckman Coulter Diagnostics
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Lab-on-a-chip

Multiplexed lab-on-a-chip bioassays for testing antibodies against SARS-CoV 2 and its variants in multiple individuals

The coronavirus pandemic caused by SARS-CoV-2 and its variants is still a major public safety issue worldwide. The “alpha” variant B.1.1.7, the “gamma” variant P.1, the “beta” variant B.1.351, and the “delta” variant B.1.617 are of particular concern because of their high prevalence. Large-scale vaccination and sensitive detection are vital for preventing the spread of Covid-19.

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Supervised learning approach

A new deep learning-based algorithm to predict relapse-free survival in papillary thyroid carcinoma

The tall cell variant (TCV) is an aggressive subtype of papillary thyroid carcinoma (PTC). Sebastian Stenman, researcher from the Institute for Molecular Medicine, and the Department of Pathology at the University of Helsinki, Finland, is developing and training a deep learning algorithm using supervised learning to detect and quantify the proportion of tall cells in PTC.

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Malignant tumour management

’Our machine learning model achieved 88.9% accuracy in predicting the sarcoma-specific survival rate’

Clinical management of soft tissue sarcoma is particularly challenging. Dr Sebastian Foersch, researcher at the Institute of Pathology at the University Medical Center in Mainz, Germany, has used a deep learning model for diagnosis and prognosis prediction of soft tissue sarcoma using conventional histopathology slides.

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Article • AI provides prognostic information

Next-generation deep learning models predict cancer survival

Deaths from cancer are currently estimated at 10 million each year worldwide. Conventional cancer staging systems aim to categorize patients into different groups with distinct outcomes. ‘However, even within a specific stage, there is often substantial variation in patient outcomes,’ Markus Plass, academic researcher from the Medical University of Graz, Austria, explained to Healthcare in…

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Article • Prediction for breast, ovarian, cervical, and endometrial carcinoma

New test detects four women’s cancers from cervical screening samples

What if a test analysing cervical cells from a gynaecological swab could be used to detect four different female cancers at an early stage and also predict cancer risk over a healthy woman's lifetime? Researchers at the EUTOPS Institute in Innsbruck, Austria, are developing tests to do just that for breast, ovarian, cervical, and endometrial cancer detection.

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