Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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Glioma detection

Breakthrough liquid biopsy test to detect mutations in brain tumours

Researchers at Massachusetts General Hospital (MGH) in Boston have developed a novel blood test using an enhanced form of liquid biopsy capable of detecting the most common types of genetic mutations…

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Detect lingering disease

Liquid biopsy for colorectal cancer could guide therapy for tumors

A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer…

Product of the month

Glucose stabilisation right from the beginning

Plasma glucose levels are essential for the evaluation of diabetes mellitus as well as gestational diabetes. Diabetes mellitus is one of the most common metabolic disorders in the world. The…

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Preparing for the future

Digital pathology dawns in developing countries

"Given the rapid transition towards digitisation, digital pathology is now unquestionably the future", reports pathologist Dr Talat Zehra from Pakistan. "However, some pathologists, particularly in underdeveloped countries, are still reluctant to accept its place in their labs. Among their many reasons, some feel that histopathology is a very complex and subjective field and artificial intelligence (AI) software cannot cope with all the issues. Conversely, pathologists are also scared that artificial intelligence (AI) might replace them completely."

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Portable testing solution

A corona lab that fits in a suitcase

The PCR test is the most accurate tool to identify SARS-CoV-2. However, valid results are often available only after days. Moreover, the laboratory must be well equipped, have trained personnel and…

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New gargle test

Mass spectrometry to improve Covid testing

A UK biotech laboratory has used mass spectrometry in a new approach to coronavirus testing. MAP Sciences developed a gargle test, which collects samples from the back of the throat, and avoids the…

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Detection of traumatic brain injury (TBI)

First rapid handheld blood test for concussions receives FDA clearance

Abbott has received 510(k) clearance for the first rapid handheld traumatic brain injury (TBI) blood test, which will help clinicians assess individuals with suspected mild TBIs, including…

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Multiphoton microscopy gives new insights

Microscopic behaviour of developing breast cells uncovered

An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. This new protocol provides detailed instructions on how to…

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Temperature range from 0°C to -85°C

Ultra-freezers for safe vaccine and sample storage

Temperature control equipment and systems company Lauda is expanding its portfolio with its new Versafreeze product line. This consists of high-quality ultra-freezers which have been optimized for…

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Wako β-glucan test

Better detection and diagnosis of fungal infections

Beta-glucan tests are proving to be pivotal in the better detection and diagnosis of fungal infections. As a robust complimentary test for traditional testing techniques and biomarkers, it is helping…

Products from Labbook

Siemens Healthineers – ADVIA 2120i Hematology System

Blood Cell Counter

Siemens Healthineers – ADVIA 2120i Hematology System

Siemens Healthineers
Mindray – BS-800M Clinical Chemisty Analyzer

Clinical Chemistry

Mindray – BS-800M Clinical Chemisty Analyzer

Shenzhen Mindray Bio-Medical Electronics Co., Ltd
DRG Instruments – DRG:Hybrid-XL

Immunochemistry

DRG Instruments – DRG:Hybrid-XL

DRG Instruments GmbH
Mindray – BC-6200 / 6000 Auto Hematology Analyzer

Blood Cell Couner

Mindray – BC-6200 / 6000 Auto Hematology Analyzer

Shenzhen Mindray Bio-Medical Electronics Co., Ltd
Shimadzu – Axima iDplus Performance

Mass Spectrometry

Shimadzu – Axima iDplus Performance

Shimadzu Europa GmbH
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MHH SARS-CoV-2 Antigen Rapid Test Kit

First Covid-19 test 'made in Poland'

To date, testing for SARS-CoV-2 infection mostly has relied on RT-PCR performed on a nasopharyngeal specimen. This testing method is very unpleasant for a patient: the professional tester has to tilt the patient’s head back slightly about 45°-70° to straighten the passage from the front of the nose, insert the swab through the nostril parallel to the palate, and the swab should reach a depth…

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Early detection

Blood-based methylation test offers promising data on lung cancer detection

In-vitro diagnostics company Universal Diagnostics (UDX) announced promising new data for its investigational blood-based lung cancer test. The data, presented at the IASLC 2020 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (#WCLC20), held virtually 28th-31st January 2021, used methylation status measurement of the tumour-derived portion from…

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Hematology

New tabletop analyzer to increase productivity and efficiency in the lab

Clinical diagnostics company Beckman Coulter announced the launch of the DxH 560 AL, a tabletop analyzer geared to reduce the time and resource constraints faced by small to mid-sized laboratories. With the analyzer’s Auto-Loading functionality, closed tube aspiration and walkaway capabilities, users can continually add up to 50 samples, provide safety against blood-borne pathogens and spend…

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New microscopy approach

A smartphone-based test for Covid-19

Researchers at the University of Arizona are developing a Covid-19 testing method that uses a smartphone microscope to analyze saliva samples and deliver results in about 10 minutes. The research team, led by biomedical engineering professor Jeong-Yeol Yoon, aims to combine the speed of existing nasal swab antigen tests with the high accuracy of nasal swab PCR, or polymerase chain reaction,…

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Coronavirus infection response

SARS-CoV-2 IgG II antibody test launched in CE Mark countries

Clinical diagnostics company Beckman Coulter launched its Access SARS-CoV-2 IgG II assay in countries accepting the CE Mark. The new Access SARS-CoV-2 IgG II assay quantitatively measures a patient’s level of antibodies in response to a previous SARS-CoV-2 infection. The ability to establish a quantitative baseline to evaluate an individual’s immune response to the SARS-CoV-2 virus allows…

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Integrated diagnostics

Joining radiology and pathology solutions

Medical imaging IT and cybersecurity company Sectra has received an order for its digital pathology solution from Amsterdam UMC in the Netherlands. This follows a recently announced radiology imaging contract. With radiology and pathology in one joint solution, Amsterdam UMC will be able to conveniently share images and information between the two medical specialties, enabling efficient…

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Neuroimaging research

Using mass spectrometry to diagnose brain diseases

To quickly and correctly diagnose diseases, medical professionals depend on identifying what biochemicals are present in tissue sections, where the biomolecules are, and at what concentrations. Mass spectrometry imaging—which can identify multiple biochemicals in a single experiment—is a promising technique to achieve this. However, the stability of biomolecular sampling needs improvement to…

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Second opinion from afar

Telepathology: a prime application of digital pathology

Telepathology remains the number one application for digital pathology, according to a leading expert in the field. Speaking to the 7th Digital Pathology and AI Congress: Europe, Professor Liron Pantanowitz outlined the advances in telepathology over recent years, and how it has facilitated access to broader expertise, image sharing and rapid second opinions, even while a surgeon is operating on…

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AI use in clinical diagnosis

Deep learning tool predicts tumour expression from whole slide images

A deep learning model to predict RNA-Seq expression of tumours from whole slide images was among the industry innovations outlined at the 7th Digital Pathology and AI Congress for Europe. Created by French-American start-up Owkin, the detail of how the company’s HE2RNA model provides virtual spatialization of gene expression was detailed to online delegates by senior translational scientist…

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Machine learning advances diagnostics and prognostics

Computerized image analysis can predict cancer outcomes

The advent of digital pathology is offering a unique opportunity to develop computerized image analysis methods to diagnose disease and predict outcomes for cancer patients from histopathology tissue sections. Such advances can help predict risk of recurrence, disease aggressiveness and long-term survival, according to a leading expert in the field, Professor Anant Madabhushi from Case Western…

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Applications of machine learning

Training AI to predict outcomes for cancer patients

Predicting the outcome of cancer can help the clinical decision-making process related to a patient’s treatment. The potential for Artificial Intelligence (AI) to support this was a key facet of the final keynote speech to the online 7th Digital Pathology and AI Congress: Europe, by Johan Lundin, Research Director at the Institute for Molecular Medicine Finland (FIMM) at the University of…

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Getting rid of the clutter

Bringing digital pathology to the hospital environment

It is a simple image of two desks in a hospital pathology department, taken a matter of months apart. But there can be few more vivid images that illustrate the changing world of pathology as the specialty forges ahead into the digital era. The image was taken by Dr Solène-Florence Kammerer-Jacquet during the transition towards digital pathology at Rennes University Hospital in France in the…

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Digital pathology

An exciting new era for tissue microarrays

A new generation of tissue microarrays are delivering more efficient and time-effective solutions to answering complex clinical and scientific questions. Sitting at the core of this new approach is digital pathology, allowing specific and targeted analysis of small areas of tissue. Latest developments in the approach were outlined by Professor Inti Zlobec at an online session of the 7th Digital…

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Frontal part of the nose

Covid-19 Antigen Test: CE Mark for easier sample collection

Siemens Healthineers announced CE mark has been achieved to use anterior nose swab sampling for the Clinitest Rapid Covid-19 Antigen test. This sampling method can be less cumbersome and time consuming for both the provider and the patient. The test is a point-of-care cassette test that does not require laboratory instruments or specialized lab personnel to administer, and it delivers results in…

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Toxins in the gut

Connecting our microbiome to breast cancer development

A microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers, according to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Breast tissue cells exposed to this toxin retain a long-term memory, increasing the…

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Enzyme Linked Immunosorbent Assay

Startup develops breakthrough IgG antibody test for Covid-19

ZTA Biotech, a Budapest-based biotech startup, has developed a Covid-19 antibody (IgG) test using the ELISA protocol. This new detection method represents a great step forward in determining if patients have had a coronavirus infection and if they might still have immunity to the disease. Early results have proven 100% in specificity after testing 280 samples, and 100% sensitivity by testing 260…

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Coping with Covid-19

How to work in the lab (while staying at home)

Inspired by remotely controlled surgical robots, professor and Vici laureate Jaime Gómez Rivas turned the corona crisis into an opportunity. He started to transform his lab into a remotely controlled experimental facility. And with success: the first paper based on entirely remote measurements is about to be published. ‘As soon as the lockdown began in March, I sat down and had a chat with my…

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Preventing endoscope contamination

Ways to enhance hygiene in endoscopy

Stringent endoscope cleaning between procedures is vital. However, with so many steps in the process – plus high demand for rapid turnaround of endoscopes – contamination and biofilm build-up are still being reported. Endoscope hygiene and cleaning protocols were central to an online event organised by Pentax Medical, with important contributions from leading specialists. The event examined…

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Point-of-care testing

epoc NXS Host Mobile Computer for POCT received CE, FDA clearance

Siemens Healthineers announced it has received CE Mark and 510(k) clearance from the U.S. Food and Drug Administration for the epoc NXS Host mobile computer. The epoc Blood Analysis System with the new epoc NXS Host offers an easy-to-use, hand-held device with intuitive software application to further advance point-of-care testing. The epoc NXS Host incorporates caregiver suggestions that enhance…

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In-vitro diagnostics

Join Mindray at 2020 AACC Virtual Event

The 2020 AACC Annual Scientific Meeting & Clinical Lab Expo is just around the corner, and this year, we are going virtual! At Mindray, we are dedicated to empowering TRUST through technology, innovation, and commitment to the advances of science in the in-vitro diagnostics field. Join our virtual community now, and explore Mindray’s reliable solutions trusted by laboratories worldwide. You…

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