Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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Two years earlier

Breast cancer: blood test could detecting relapse earlier

Research has revealed that a new blood test is able to detect disease relapse up to two years earlier than imaging in patients with early-stage breast cancer. The research, carried out by the…

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Infectious disease

Sensor technology could detect Dengue fever earlier

Researchers from the University of Bath are developing a new tool for detecting the presence of Dengue fever early on, helping prevent people from suffering potential life-threatening complications.

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MRSA

Decolonization protocol can prevent dangerous infections

Antiseptic soap, mouthwash, and nose ointment after hospital discharge reduced infections and infection-associated hospitalizations due to MRSA in high-risk patients. Hospital patients who have…

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Emergency medicine

D-dimer POCT for DVT considered ‘game-changer’ in ambulatory care

Radiometer Limited’s AQT90 FLEX analysers have been used in a successful trial to asses D-dimer point-of-care testing (POCT) for suspected lower limb deep vein thrombosis (DVT). The editorial…

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NSCLC

Liquid biopsy as effective as tissue biopsy for non-small cell lung cancer

Test more accurately identifies four mutations for which FDA-approved drugs exist and offers faster turn-around time between initial testing and commencement of therapy.

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Lab equipment

Horiba launches D-Dimer hematology reagent

Horiba Medical announces the availability of a D-Dimer reagent for their semi-automated Hemostasis instruments. The D-Dimer is a key measurement and the reference exclusion test for the diagnosis of…

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Immuno-oncological biomarkers

Seeking to augment the value of tumour infiltrating lymphocytes

Measuring tumour infiltrating lymphocytes (TILs) is gaining importance in immunotherapy, but other variables must also be considered to boost prognosis and prediction accuracy, a leading pathologist…

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Getting personal(ised)

Pathology: Moving us towards precision medicine

The European Society of Pathology (ESP) holds its European Congress of Pathology (ECP) at different venues annually. This year, in Spain, 3,448 delegates from 87 countries attended. There, ESP…

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From the heart

Finding the 'fingerprint' of cardiovascular disease

Forty-two percent of all deaths in the United States are related to cardiovascular disease (CVD). According to the Global Cardiovascular Drugs Market Forecast, by 2030 the number of deaths from CVD…

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Diagnostics

Heat it and read it

You’re sweating and feverish and have no idea why. Fortunately, Sandia National Laboratories scientists have built a device that can pinpoint what’s wrong in less than an hour. Unlike most…

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breast cancer

System images molecular features of cancer tissue in real-time

A team of University of Illinois at Urbana-Champaign researchers led by Bioengineering Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly…

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Shimadzu Europa 50th anniversary

Mass spectrometry and ever more…

As Shimadzu celebrates its 50th anniversary in Europe, we spoke with Stéphane Moreau, Manager of LC-MS & Life Sciences at the Marketing Europe/Analytical Business Unit of Shimadzu Europa GmbH,…

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Non-invasive diagnostics

Detecting bladder cancer with atomic force microscopy

A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical…

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Early diagnosis

New blood test detects early stage ovarian cancer

Research on a bacterial toxin first discovered in Adelaide has led to the development a new blood test for the early diagnosis of ovarian cancer - a disease which kills around 150,000 women globally…

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New treatment options

Unlocking the secrets of cell communication

Portland State University (PSU) researchers have made a significant breakthrough by developing the 3-D structure of proteins from inside the eye lens that control how cells communicate with each…

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Targeted treatment

Cancer: Blood sample to help select the right early phase clinical trials

Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analysing the genetic faults in a sample of their blood. The…

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New hematologic biomarker

FDA clearance for early sepsis indicator

A major milestone on its strategic mission to lead in sepsis diagnostics, Beckman Coulter announced that its Early Sepsis Indicator has received 510(k) clearance from the U.S. Food and Drug…

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Genetics

Sequencing methods – unfold the full potential for hospitals

Gene sequencing has been progressing in leaps and bounds over the past few years. The process of determining the order of nucleotides in DNA has become faster and more precise. Moreover, today both…

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Clinical chemistry

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New staining technology

Staining is an art – ColorAX2 will become your favourite artist

ColorAX2 with its new staining technology offers you low staining reagents consumption. The compact, lightweight and autonomous system features 10 independent staining chambers and allows easy and clean procedures. The unique technology of ColorAX2 prevents cross-contamination and significantly reduces the consumption of reagents and waste. Besides it helps you reduce your operation costs. The…

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Infection control

Knowledge is one thing - implementation another

Insufficient knowledge of infection control, resulting in insufficient compliance, increases the risk of hospital acquired infections (HAIs) and multiresistant pathogens that put patients at risk. At the 2019 Annual General Meeting of the German Society for Hygiene and Microbiology e.V. (DGHM) in Göttingen, Professor Frauke Mattner, Senior Consultant at the Institute of Hygiene, Kliniken der…

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Antimicrobial resistance

Apocalypse postponed: upcoming antibiotics bring hope

Antimicrobial resistance is a global issue, with 700,000 deaths per year and 10 million expected deaths by 2050, according to predictions. Appropriate antimicrobial therapy can help to save lives, and a long awaited cure for carbapenemase-producing enterobacteriaceae (CPE) will soon be released, according to eminent Spanish expert Jose Mensa Pueyo, speaking at a Madrid meeting in March. The past…

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Carbapenemase producing enterobacteriaceae

Detecting drug-resistant CPE quickly is still a challenge

Early detection and confirmation of carbapenemase-producing enterobacteriaceae (CPE) are essential when choosing the appropriate antimicrobial therapy and to implement infection control measures. Here, a leading Spanish microbiologist reviews an arsenal of tools currently available to clinicians. Resistance to beta-lactam antibiotics in enterobacteriaceae (EBc) is due to one or more of these…

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Hospital hygiene

Nosocomial infections: a positive trend, but...

Hospital hygiene and how Germany compares in a European survey is somewhat divisive. Some believe Germany does well, whilst others emphasise the need to improve and for a stronger alignment with countries such as the Netherlands. As hygiene specialist Professor Petra Gastmeier, at the Institute of Hygiene and Environmental Medicine in Charité University Medical Centre Berlin, pointed out:…

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Blood transfusions

Donor organs become immunologically invisible

The safety of blood transfusions is questioned again and again by the mass media. Sometimes ‘bad’ blood causes infections; sometimes a transfusion leads to cancer years later. The fact is that transfer blood is subjected to the highest safety standards – there are very clear statutory regulations. Nonetheless, there will be shortages of ‘life’s fluid’ because, given increasing…

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Symposium @ ECCMID 2019

How laboratories can help detect AMR and sepsis sooner

Beckman Coulter, a global leader in clinical diagnostics will be demonstrating its latest comprehensive solutions in microbiology, urinalysis and hematology at the 29th European Congress of Clinical Microbiology & Infectious Diseases (ECCMID). During the conference, Beckman Coulter is also hosting a symposium where attendees will learn how the laboratory can help physicians detect…

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Rapid diagnostics

T2 Biosystems hosts integrated symposium at ECCMID 2019

T2 Biosystems, maker of rapid diagnostic technology to aid in the detection of blood stream infections to prevent sepsis, will host an integrated symposium titled “Rapid Diagnostics Direct from Whole Blood: A Solution for Fast and Appropriate Antimicrobial Therapy,” at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Amsterdam, Monday, April 15, 16:00-18:00…

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Meeting of the generations

We need a Senior Laboratory

It’s undeniable: the bulk of our population is growing older. Yet, this demographic change has not altered laboratory medicine: the reference values for many analyses are still based on data of a younger cohort. Inevitably this could lead to serious errors in the interpretation of older patients’ test results. Professor Kai Gutensohn, Managing Director and Medical Director of AescuLabor…

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ß-D Glucan

New test for early fungal infection detection

At the National Reference Centre for Invasive Fungal Infections (Hans-Knöll Institute Jena) and the Institute for Hygiene and Microbiology, Würzburg University, Professor Oliver Kurzai and team utilise the fast and user-friendly β-D-Glucan Test, supplied by Fujifilm Wako Chemicals Europe GmbH, to check immunocompromised patients for signs of life-threatening, invasive fungal infections.…

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Linked laboratories

New Dutch digital pathology advances

Efforts have been made to digitise pathology in the Netherlands, where the Dutch pathology network PALGA has run since 1990, connecting all of the Netherlands’ laboratories. Paul J van Diest, head of the pathology department at the Utrecht University Medical Centre, presented the brand new Dutch digital pathology platform during ECP 2018. Launched this year, this enables quicker, easier…

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POC analysis

A revolution in HbA1c measurement

Quo-Lab® HbA1c is a desktop point-of-care analyzer for measuring glycated hemoglobin (HbA1c). The semi-automated analyzer has been designed specifically to meet the needs of diabetes clinics and laboratories in settings that demand low cost of operation and ease of use. From a simple procedure, Quo-Lab provides lab-accurate test results within four minutes (CV < 3% at 7% A1c) from a venous or…

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Going digital

Faster and better diagnosis of cancer with digital pathology

Leeds Teaching Hospitals NHS Trust and the University of Leeds have announced a critical milestone in going digital, by scanning every glass slide they produce. The milestone represents a major step towards achieving faster and accurate diagnosis for cancer patients in the future. The Pathology Department, located in St. James’ Hospital in Leeds, is one of the largest in the UK processing over…

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Evolving technique

Flow cytometry rises to new challenges

Flow cytometry has proved an invaluable diagnostic tool for leukaemia and lymphoma for almost three decades. Now, however, this is evolving in applications to seek out residual disease in cases and in fusion with molecular testing to advance its diagnostic potential. However, although recognised as fast, flexible and accurate, flow cytometry suffers from a lack of standardisation, according to…

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Handheld devices

The pocket-size lactate monitor

Made by EKF Diagnostics, the Lactate Scout 4 hand-held analyser is a fast, accurate sports performance monitoring device designed for use as a training companion for individuals or sports teams. This year at Medica the manufacturer is showing the new analyser plus many POC testing devices, including the recently FDA cleared DiaSpect Tm haemoglobin analyser and Quo-Lab® HbA1c analyser that was…

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Real walkaway automation

The all-in-one molecular laboratory system

The lab-in-the-box design of LabTurbo SP-qPCR All-in-one system offers true automation for the molecular laboratory, the manufacturer reports, adding that this ‘delivers testing confidence and laboratory efficiency. LabTurbo fully automates the complete workflow of molecular diagnostic laboratories. The sample-to-result procedure includes: automatic sample transfer from primary tubes, DNA/RNA…

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Interdisciplinary

Exploring the human microbiome

During the International Forum for Laboratory Medicine, one seminar focused on infectious diseases. Professor André Gessner, from the Medical Microbiology and Hygiene Department at Regensburg University, lectured on ‘The human microbiome, an explosive ‘climate’ topic,’ he explained. 'I have given many lectures to heterogeneous audiences and find the challenge of explaining complex…

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High quality products

High frequency plastic welding

At UK firm Speed Plastics, a team of expert engineers transforms ideas into commercial products that are ready for sale, by providing a complete design and development service from the initial concept. Based in Chesterfield, the company is a proud partner to a number of United Kingdom healthcare companies, working as an extension to their in-house capabilities.

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Fully automated coagulation analyzers

HORIBA Medical launches Yumizen G1500/G1550

HORIBA Medical announces that the Yumizen G1500 (open tube) and Yumizen G1550 (closed tube) are now available. These fully automated analyzers can manage the diagnostic and monitoring requirements of clinical laboratories with a mid to high workload. Expanding their field of blood-diseases expertise, directly linked to hematology, HORIBA Medical is now able to offer its customers, dedicated and…

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Pathology equipment

KUGEL medical – Eco-friendly tissue grossing station GrossPath GP-1500

GrossPath – the special worktable designed to ensure a pollution free, laboratory-grade working environment for slicing and preparing histological slide preparations. Its compact design makes the GrossPath Special Worktable the perfect laboratory equipment, especially for small facilities. As a product of our ECOline range, this worktable has been designed with a special view to conserving…

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Pathology testing

Multimillion-Dollar investment in the Atellica Solution in Australia

Integrated healthcare provider Primary Health Care has joined forces with Siemens Healthineers to deploy more than 70 Atellica Solution immunoassay and clinical chemistry analyzers. This marks Siemens Healthineers largest contract for in vitro diagnostics testing in Australia, and one of its most robust sales of the Atellica Solution. The analyzers are integrated with Atellica Diagnostics IT…

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Artificial intelligence

UK Government and Philips consortium co-invest in digital pathology

Royal Philips has been leading two healthcare innovation projects that will receive government investment as part of major cross-sector collaborations with the NHS, academia and industry partners from the UK Government’s Industrial Strategy Challenge Fund, delivered through United Kingdom Research and Innovation (UKRI). A joint multi-million pound investment by government and industry partners,…

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Product of the month

Faster decision making with Olympus’ intelligent DP74 camera

Accelerate your workflow with the intelligent, high-resolution DP74 brightfield and fluorescence camera from Olympus. Histologists and pathologists face intense, rushed workloads where every minute counts. Experience enhanced efficiency with our next-generation camera. The DP74 creates a map of where you’ve been and can easily and rapidly lead you back to previous positions on the sample,…

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