Myelodysplastic syndrome

Genetic testing helps predict disease recurrence

A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders…

Research

First evidence that soot from polluted air is reaching placenta

Evidence of tiny particles of carbon, typically created by burning fossil fuels, has been found in placentas for the first time, in new research presented at the European Respiratory Society…

World Alzheimer’s Awareness Month

Robot helps with early screening for Alzheimer’s patients

Alzheimer’s is the most common form of dementia. The US Centers for Disease Control and Prevention reports as many as five million Americans had the disease in 2013. They estimate that by 2050,…

Non-compliance

Half of European clinical trials do not report results

Half of clinical trials on the EU register have not reported results, despite rules requiring results to be posted within 12 months of completion, finds a study published by The BMJ. Findings show…

Study

Liver disease drug could help restore cells damaged by Alzheimer's

A drug which has been used to treat liver disease for decades could help to restore cells damaged by Alzheimer's, a new study from the University of Sheffield has found. The pioneering study…

Research

Link between obesity, the brain, and genetics

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.…

From science fiction to reality

Researchers 3D print prototype for bionic eye

A team of researchers at the University of Minnesota have, for the first time, fully 3D printed an array of light receptors on a hemispherical surface. This discovery marks a significant step toward…

Cardiology

Do our hearts beat digital or analog?

Scientists at the Virginia Tech Carilion Research Institute (VTCRI) have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart — a discovery…

Promising research

First steps towards a new, targeted lung cancer treatment

Scientists have identified a key molecular player in a subtype of lung cancer which could lead to a new way to tackle the disease, according to research published in Nature Communications. They found…

Boxers or briefs?

Why getting rid of tighty-whities is good for your fertility

Researchers have discovered a good reason to not wear tight-fitting underwear – beyond the obvious aspect of fashion: According to new research led by Harvard T.H. Chan School of Public Health, men…

Morbus Charcot-Marie-Tooth

CMT: Unlikely ally against deadly neuropathy

Charcot-Marie-Tooth (CMT) disease is the most common hereditary neuropathy and affects more than two million people worldwide. In Germany, at least 30.000 people suffer from CMT which belongs to the…

Autophagy

Pathway Ebola virus uses to enter cells pinpointed

The new outbreak of the deadly Ebola virus declared just last week in eastern Democratic Republic of Congo is believed to have claimed more than 30 victims so far, highlighting the continued urgency…

Neural development

Why our brains fold the way they do

Everyone knows what our brains look like – but why is it folded up like that? Looking at other species reveals much less folding or even none at all. Scientists in Dresden, Germany, have now taken…

Sodium consumption

Daily salt intake: How much is too much for our heart?

New research shows that for the vast majority of individuals, sodium consumption does not increase health risks except for those who eat more than five grams a day, the equivalent of 2.5 teaspoons of…

Mysterious illness

Potential diagnostic test for Kawasaki disease

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki disease (KD) can…

Hazardous hormones & the heart

How being transgender affects cardiac health

Transgender individuals may be at higher risk for myocardial infarction and death due to cardiovascular disease, according to several studies. This increased risk may be due to the hormone therapy…

Henipaviruses

Lethal viruses hijack cellular defences against cancer

Monash University’s Biomedicine Discovery Institute (BDI) researchers have identified a new mechanism used by Henipaviruses in infection, and potential new targets for antivirals to treat them.…

Switching sides

How cancer cells 'brainwash' their foes

It doesn’t often happen that army generals switch sides in the middle of a war, but when cancer is attacking, it may cause even a gene that acts as the body’s master defender to change…

Dementia

Drinking will put your brain at risk (but then again, abstinence might, too)

People who abstain from alcohol or consume more than 14 units a week during middle age (midlife) are at increased risk of developing dementia, finds a study in The BMJ today. However, the underlying…

Radiation research

How smartphones take the 'smart' out of youths

The electromagnetic radiation emitted from smartphones and similar devices may have negative effects on the memory of young people. Research conducted in Switzerland suggests that it might be a good…

Tumor research

Growing brain cancer in a dish

Austrian researchers have accomplished an astounding feat: They created organoids that mimic the onset of brain cancer. This method not only sheds light on the complex biology of human brain tumors…

Research

Growing a human esophagus in the lab

Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids.

Infections

Zika virus strips immune cells of their identity

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California…

Oncology

Discovering cancer cell mutations with optimized technologies

Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a…

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Hope against arthritis

Growing cartilage – how does it work?

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage. Their findings appear in Nature…

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Research

Zika virus proteins inhibit brain development

In healthy individuals, the Zika virus causes flu-like symptoms. If a pregnant woman becomes infected, the unborn child can suffer from severe brain abnormalities as a result of mechanisms that have not yet been explained. A study by the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry (MPI-B) shows that Zika virus proteins bind to cellular proteins that are…

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Weak heart

The many causes of dilated cardiomyopathy

A major study has been launched to investigate the interaction between genes and lifestyle factors and dilated cardiomyopathy (DCM). Led by Professor Stuart Cook, at the National Heart and Lung Institute, this, the largest ever DCM study, will investigate why people develop DCM, with a focus on who is most at risk of sudden death or heart failure (HF). Six hospital trusts across England –…

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Cardiology congress

ESC 2018: At the heart of research

When delegates from around 150 countries converge on Munich for ESC Congress 2018 they will no doubt reflect on what they themselves eat. Yes, nutrition is up for debate, questioning, for example, whether weight loss therapies can also prevent heart attacks and strokes. Results from the CAMELLIA-TIMI 61 trial of 12,000 overweight individuals with established cardiovascular disease or diabetes…

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Resistance-building

‘Why not take a risk?’ belief boosts antibiotic overuse

Antibiotics are mostly prescribed for acute respiratory infections (ARIs), yet most of these infections are viral. A new study shows that inappropriate antibiotics prescriptions are widespread, contributing dangerously helping antibiotic-resistant organisms to grow. Overuse could be due to attitudes among patients and clinicians, current George Washington University research suggests.

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High blood pressure

Millions more: New guidelines could drastically raise hypertension numbers

Adopting new guidelines for high blood pressure (hypertension) would dramatically increase the number of people labeled as having the condition and being recommended for drug treatment, finds a study published by The BMJ today. The findings show that, if the guidelines were introduced in the US and China, more than half of those aged 45-75 years in both countries would be considered hypertensive.

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Infections

Zika suppresses virus fighting cells

More than two years after reports of skyrocketing Zika rates surfaced worldwide, questions still loom about this complicated virus. Professor of Biological Science Hengli Tang and his postdoctoral researcher Jianshe Lang from the Florida State University take a deep dive into the differences between Zika and the Dengue virus.

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Research

Unravelling the mystery of non-alcoholic fatty liver disease

Another piece in the puzzle that is non-alcoholic fatty liver disease has been solved by a University of Queensland researcher in a step towards developing treatments for a disease that affects about one in every five Australians. PhD student Laurence Britton has discovered a pivotal mechanism by which iron is able to make the liver more vulnerable to the injury and metabolic dysfunction that…

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Promising research

Could senescence be the key to stopping cancer?

Canadian researchers have found a promising way to stop tumour cells from multiplying. In disrupting the composition of ribosomes, the team from Université de Montréal (UdeM) discovered a direct molecular mechanism to stop cancer cells from proliferating, which is called senescence. Their results have been published in Nature Cell Biology. 
“Ribosomes are complex machines composed of both…

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Live long and prosper

Key molecule of aging discovered

Every cell and every organism ages sooner or later. But why is this so? Scientists at the German Cancer Research Center in Heidelberg have now discovered for the first time a protein that represents a central switching point in the aging process. It controls the life span of an individual - from the fly to the human being. This opens up new possibilities for developing therapies against…

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Behaviour prediction

The psychology of taking risks

An anxious person will avoid risks whenever possible. This in itself is not exactly a surprise. However, researchers have found a way to visualize this process in the brain - with interesting implications for behaviour prediction. A team of psychologists from the German Friedrich Schiller University Jena, together with partners from Würzburg, Germany and Victoria, Canada they conducted an…

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Hand in hand

Why being left-handed matters for mental health treatment

Being left-handed apparently means a lot more than gripping things differently than most, researchers find. This sheds a new light on mental health treatment, because current therapies for the most common mental health problems could be ineffective or even detrimental to about 50 percent of the population. For more than 40 years, hundreds of studies suggest that each hemisphere of the brain is…

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Faster diagnosis, reduced cost

The impact of whole genome sequencing on newborn babys in ICU

Early whole genome sequencing might bring hope for children who are born severely ill or who develop serious illness in the first few weeks of their life. Because these children are often difficult to diagnose, detection of diseases has considerable implications for their short and longer-term care. At the annual conference of the European Society of Human Genetics (ESHG) in Milan, Italy, the…

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Neurology

Waves move across the human brain to support memory

Biomedical engineers at Columbia Engineering have discovered a new fundamental feature of brain oscillations: they actually move rhythmically across the brain, reflecting patterns of neuronal activity that propagate across the cortex. The coordination of neural activity across widespread brain networks is essential for human cognition. Researchers have long assumed that oscillations in the brain,…

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Research

Maps made of nerve cells

Dr. Thomas Hainmüller and Prof. Dr. Marlene Bartos of the Institute of Physiology of the University of Freiburg have established a new model to explain how the brain stores memories of tangible events. The model is based on an experiment that involved mice seeking a place where they received rewards in a virtual environment.

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