Research

Welcome to healthcare-in-europe.com, THE European forum for news and innovation in medical technology. Read more about promising studies and trials that lead to more effective drugs, procedures as well as medical guidelines.

Minds connected

Parents’ brains ‘sync up’ with their infant’s when they play together

When infants are playing with objects, their early attempts to pay attention to things are accompanied by bursts of high-frequency activity in their brain. But what happens when parents play together…

Benefits of childbirth

Breast cancer: Pregnancy gives (delayed) protection

In general, women who have had children have a lower risk of breast cancer compared to women who have never given birth. However, new research has found that moms don’t experience this breast…

Immune-boosting substance

This gel could help the body after cancer surgery

Many people who are diagnosed with cancer will undergo some type of surgery to treat their disease — almost 95 percent of people with early-diagnosed breast cancer will require surgery and it’s…

Stem cell research

Brain confetti - why our sense of smell declines when we get old

As mammals age, their sense of smell deteriorates. In a study published in the journal ‘Cell Reports’, an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case. For their study, the researchers tracked the development of stem cells in the brains of mice using what are known as confetti reporters. They then analysed the complex data obtained using intelligent algorithms. In mammals, generation of new neurons (neurogenesis) is mainly limited to early childhood and occurs in adulthood only in a few regions of the forebrain. One such exception is olfactory neurons, which develop from stem cells via several intermediate stages.

Guselkumab vs Secukinumab

Psoriasis: New data point to improved treatment

The Janssen Pharmaceutical Companies of Johnson & Johnson announced results from the ECLIPSE study demonstrating that Tremfya® (guselkumab) was superior to Cosentyx® (secukinumab)* in treating…

Intracerebral hemorrhage

Can sudden weather change raise stroke risk?

A collaborative study led by a neurologist at Rush University Medical Center and an environmental scientist at the University of Illinois at Chicago suggests that weather patterns that cause dramatic…

Controversial research

HIV and gene editing: beware of the butterfly effect, cautions expert

The claim of a chinese professor has caused quite a controversy: He Jiankui announced that he successfully modified human DNA to prevent two girls from contracting HIV. Upon the leak of this…

Photonic endoscopy

Fibre probe explores the depth of our brain

This could be a major step towards a better understanding of the functions of deeply hidden brain compartments, such as the formation of memories, as well as related dysfunctions, including…

Klotho

Could a ’longevity protein’ be the key to rejuvenating muscles?

One of the downsides to getting older is that skeletal muscle loses its ability to heal after injury. New research from the University of Pittsburgh implicates the so-called “longevity protein”…

Unhealthy lifestyle

How working night shifts raises your risk of type 2 diabetes

Women who work intermittent night shifts and do not follow a healthy lifestyle face an especially high risk of type 2 diabetes, suggests a study published by The BMJ. The researchers found that the…

Deadly DNA

Suicide: Is it in our genes?

Suicide is the 10th leading cause of death in the United States, claiming more than 44,000 people in the country every year, similar to the number of deaths caused by the opioid epidemic. Previous…

Hypotrichosis

Hair loss? This gene might be to blame

Hypotrichosis simplex leads to progressive hair loss already in childhood. A team of researchers led by human geneticists at the University Hospital of Bonn has now deciphered a new gene that is…

Cancer research

Seeking a vaccine to prevent lethal pneumonia

Mariette Barbier, an assistant professor in the West Virginia University School of Medicine, and her research team are investigating ways to keep cystic fibrosis patients and other at-risk…

Neuroscience

"Neuropixels" neural probe to map brain activity

Imec, the world-leading research and innovation hub in nanoelectronics and digital technologies, released and is making available its state-of-the-art high-density neural probe, Neuropixels, to the…

Blood pressure

How does the baroreceptor reflex work?

The baroreceptor reflex is a fascinating medical phenomenon. The reflex is controlled by specialized neurons that react in just a fraction of a second to keep blood pressure fairly consistent. For…

It's all connected

Understanding the "wiring diagrams" of genes in complex tissues

How is the activity of all genes in cells of higher organisms interconnected? And how are the genetic "wiring diagrams" of the cells in complex tissues coordinated with each other?…

Glucose metabolism

Sugar and stress: how are they connected?

Chronic stress is a well-known risk factor for the development of psychiatric illnesses including depression disorders. The brain requires a great deal of glucose, and stress is known to alter…

Glioblastoma

Building a better model for brain tumours

A research team led by the University of Alabama at Birmingham is launching a study to find a better model for glioblastoma, a particularly devastating type of brain tumour, to help determine the…

Innovative material

'Smart' surfaces might pave the way for safer implants and better diagnostics

Researchers at McMaster University have solved a vexing problem by engineering surface coatings that can repel everything, such as bacteria, viruses and living cells, but can be modified to permit…

Cause and effect

Diabetes and heart failure: discovering the connection

Men with diabetes are 2.4 times more likely than non-diabetics to suffer heart failure and women are five times more likely. But why? A new Loyola University Chicago Stritch School of Medicine study…

Mysterious blackout

What happens when we lose consciousness during anaesthesia?

The first successful surgery under anaesthesia occurred in the 1840s. Since then—more than 170 years later—people have been developing theories about what might be going on in the brain while a…

Tuberculosis

So did drug resistant TB evolve and spread globally

The most common form of Mycobacterium tuberculosis (TB) originated in Europe and spread to Asia, Africa and the Americas with European explorers and colonialists, reveals a new study led by UCL and…

Comorbidity

Mapping out the relationship between mental disorders

Half of those who develop a severe mental disorder such as depression prior to the age 20, will also develop an anxiety disorder within the next 15 years. This is just one of the many results on the…

Precision medicine

Europe looks to cells for a healthier future

How can we detect the first signs of disease as early as possible? Could closer investigation at the cellular level help to quickly prevent disease progression through appropriate treatment? The…

DMD & rhabdomyosarcoma

Duchenne muscular dystrophy: Muscle stem cells can drive cancer

People with Duchenne muscular dystrophy (DMD) can develop an otherwise-rare muscle cancer, called rhabdomyosarcoma, due to the muscle cells’ continuous work to rebuild the damaged tissue. However,…

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Silicon photonics

New device for screening arterial stiffness and diagnosing CVD

Researchers have developed a prototype medical device based on silicon photonics for the screening of arterial stiffness and for the diagnosis of cardiovascular diseases such as arterial stenosis and heart failure. This is a cooperation between imec, the world-leading research and innovation hub in nanoelectronics and digital technology and Ghent University, together with Medtronic and other…

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Facebook, Twitter, Snapchat

Millennials' social media activity may increase depression risk

A new study by a team of Texas State University researchers shows that negative social media behaviors are linked to major depressive disorder (MDD) in Millennials. The findings are published in the Journal of Applied Biobehavioral Research. In the study of 504 Millennials who actively use Facebook, Twitter, Instagram and/or Snapchat, individuals who met the criteria for MDD scored higher on the…

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Blockage detection

This blood flow sensor wraps around the blood vessel

A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor, detailed in a paper published in Nature Biomedical Engineering, monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if…

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Mengla filovirus

Researchers discover Ebola-related virus carried by bats

Researchers from Singapore’s Duke-NUS Medical School, in collaboration with scientists in China, have identified and characterised a new genus of filovirus from a Rousettus bat in China. Their findings were published in the journal Nature Microbiology. Bat-borne viruses around the world pose a threat to human and animal health. Filoviruses, especially Ebola virus and Marburg virus, are…

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Choline

Essential nutrient holds promise against Alzheimer’s

In a new study, researchers at the Biodesign Institute explore a safe and simple treatment for one of the most devastating and perplexing afflictions: Alzheimer’s disease (AD). Lead authors Ramon Velazquez and Salvatore Oddo, along with their colleagues in the Arizona State University (ASU)-Banner Neurodegenerative Disease Research Center (NDRC), investigate the effects of choline, an important…

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Electric wound care

This E-bandage could speed up wound healing

Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats. They report their results in ACS Nano. Chronic skin wounds…

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Aftercare

Discharged ICU patients need careful rehabilitation

Care models that go beyond rehabilitation services and are aimed at a smooth transition from intensive to aftercare are not established in Germany. A working group around Professor Dr Christian Apfelbacher at the Institute for Epidemiology and Preventive Medicine, Regensburg University, is currently developing a concept for intensive out-patient aftercare. ‘The project is to help improve the…

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'Tis the season to be healthy

10 simple tips to keep Christmas overindulgence at bay

Christmas cookies, mulled wine and an extensive family feast - it seems impossible not to gain weight during the holidays. But there's hope: A study by the University of Birmingham and Loughborough University has shown that regular weighing at home and simple tips to curb excess eating and drinking can prevent people from piling on the pounds at Christmas. Researchers, supported by the National…

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Pregnancy

Giving birth raises risk of breast cancer in younger women

Younger women who have recently had a child may have a higher risk of breast cancer than their peers of the same age who do not have children, according to a large-scale analysis co-led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher. The findings, published in the Annals of Internal Medicine, may seem contrary to conventional wisdom that childbirth is…

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Birth outcome study

Obesity and pregnancy: A risky couple

New research from the University of Adelaide’s Robinson Research Institute supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant. The researchers have reported the results of a large study of birth outcomes in more than 500 overweight or obese women from three public maternity units in Adelaide, Australia in The Lancet Diabetes &…

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Neuro-research

Brain-computer interfaces: Getting a Grasp on how we think

A world where machines can be controlled by thought alone – such is the promise of so-called brain-computer interfaces (BCI). BCIs are both hardware and software communication systems that read brain and nerve signals, convert those into electrical signals and translate human thoughts into machine commands. Developers of BCIs rely on artificial intelligence, neural network models and big data…

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Advanced materials

Nanocarriers open up to cancer

Nanosystems that deliver anticancer drugs or imaging materials to tumours are showing significant progress, particularly those that respond to tumour-related stimuli, according to a review published in the journal Science and Technology of Advanced Materials. However, further research is still required to make sure these delivery systems are stable, non-toxic and biodegradable. Nanocarriers…

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Dying neurons

Decoding the regulation of cell survival

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden (CRTD) has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

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Chronic obstructive pulmonary disease

COPD: Biomarker for kidney disease has unexpected benefits

A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Albuminuria, Lung Function Decline, and Risk of Incident COPD: the NHLBI Pooled Cohorts Study,” Elizabeth C.…

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Painful protein

Understanding Bechterew's disease

Autoimmune diseases like Bechterew’s disease direct our immune systems agains our own bodies. Now, researchers at Jacobs University Bremen have come one step closer to understanding the molecular mechanisms of the disease also known as ankylosing spondylitis. It is characterized by long-term painful inflammation of the joints and deformation of the spine. One suspected cause is a particular…

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Myelodysplastic syndrome

Genetic testing helps predict disease recurrence

A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells. Such a practice could help doctors identify patients at high risk of disease recurrence early after a transplant and help guide treatment decisions.

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Infections

Zika virus strips immune cells of their identity

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.

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