Tumour

News • Exploring the landscape of tumour methylation

Parsing the pathology of prostate cancer

Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.

News • CRISPR-Cas9-based approach

New laboratory tool to find better treatments for resistant melanomas

Researchers have developed a new lab model to study BAP1-deficient melanomas, a rare type of melanoma that evade the immune system once they metastasize and are resistant to current immunotherapies.

News • Focus on FAP

New radiopharmaceutical therapy shows broad effectiveness across multiple cancers

Radiopharmaceutical therapy has already transformed care for neuroendocrine tumors and prostate cancer, but other tumor types still lack targeted treatment options. A new approach could change this.

Prof. Johanna Joyce

Advancing cancer research across Europe and beyond

Prof. Johanna Joyce has begun her two-year term as President of the European Association for Cancer Research (EACR), a global community of scientists and clinicians dedicated to advancing the…

News • Novel radiopharmaceutical therapy

Promising treatment option for aggressive neuroendocrine tumors

A new type of peptide receptor radionuclide therapy (PRRT) appears to be safe in metastatic neuroendocrine tumor patients who have exhausted conventional treatment options.

News • Metabolic health

Obesity helps breast cancer become invasive

Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.

News • Oncology

Nanozymes take on brain tumours from the inside

Researchers are developing nanozymes to improve treatment of aggressive brain tumours. The tiny particles can be activated by near-infrared light and applied directly during surgery.

News • Mammary tumorigenesis

New marker identifies which breast lesions will progress to cancer

Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.

News • Methylation-sensitive editing by Cas9

Targeting tumour DNA with CRISPR variant

Researchers have taken an early but promising step toward a cancer therapy that targets and destroys tumor cells with high precision, using a variant of the DNA editing tool CRISPR.

Article • Experts explore often-overlooked patient group in oncology

A rising tide: cancer in young adults

For a young adult, a cancer diagnosis hits different: a more aggressive disease course, greater disruptive potential, longer survivorship. Yet most healthcare institutions seem poorly prepared for this growing patient group. A plenary session at the NCCN 2026 Annual Conference examined a striking shift in modern oncology: the rising incidence of cancer in adolescents and young adults (AYA).

News • Prediction of treatment response

Colon and rectal cancer: new biomarker shows which patients benefit from immunotherapy

A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.

News • Biomechanical mapping of tumor growth

New biomarker helps assess glioblastoma aggressiveness

Researchers have developed a new MRI-based method that enables objective quantification of the growth of the most aggressive brain tumours, particularly glioblastoma.

News • Ependymoma and medulloblastoma tumoroids

New organoids offer deeper insights into pediatric brain cancer

Patient-derived organoids (PDOs), or tumoroids, for pediatric brain cancer show promise in helping researchers find new drugs and better understand the different responses of the tumor.

News • Unexpected similarities

Different tumours, same origin: Surprising discovery in paediatric brain cancers

Researchers discovered that pineoblastoma, retinoblastoma and medulloblastoma – severe brain tumours in children that appear to be completely different – actually arise from the same type of cell.

News • (B)eating cancer

Bacteria to consume tumours from the inside out

A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.

News • Treatment approach

How to improve cancer cure rates? “Kick it while it’s down”

Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.

News • New sequencing technique

Classifying pediatric brain tumors with liquid biopsy and AI

Clues in the CSF: Researchers have developed the first high-precision method that can theoretically diagnose common brain tumors in children and adolescents without surgery.

News • CTNNB1 in focus

Mutation strength may hold key to personalized cancer treatment

Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.

News • Focus on tumor STAT1 acetylation

How cancer cells learn under pressure to evade immunotherapy

Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.

News • New treatment approach

Ultrasound 'softens up' tumors before chemo

To soften up tumors prior to cancer chemotherapy, a team of researchers paired high-frequency ultrasound waves with a type of sound-responsive particle to reduce the protein content of the tumors.

News • Differentiation after radiotherapy

Brain tumour or radiation necrosis? AI can tell them apart

A novel AI-based method can distinguish between progressive brain tumours and radiotherapy-induced necrosis on advanced MRI. This could help clinicians more accurately identify and treat the issues.

News • Insights on IDH mutated gliomas

Brain cancer: why early treatment is not always the best course

IDH mutated gliomas are slow-growing brain tumors with a relatively good prognosis. A new study shows that many patients reveal measurable cognitive impairment in the first year after treatment.

News • Dual-barrier tumours

How colorectal cancer evades immunotherapy (and what to do about it)

Most patients with metastatic colorectal cancer do not respond to immunotherapy—but why? A new study shows how the tumours block the immune system through two complementary mechanisms.

News • Transformer-based learning from radiomics and clinical data

New AI model improves prediction of breast cancer recurrence

An international team has developed an AI model that brings together medical imaging data and clinical information to calculate the risk of breast cancer tumour recurrence more accurately.

News • Research reveals infiltrating microbes

How bacteria in tumors drive treatment resistance in cancer

Researchers have discovered a previously unknown mechanism that explains how bacteria within a tumor can drive treatment resistance in patients with oral and colorectal cancer.

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