Chronic diseases

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News • Chronic myeloid leukaemia

CML therapy response predicted by AI "crystal ball"

AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.

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News • Understanding the role of sex hormones

Multiple sclerosis: Why are women affected more often?

Multiple sclerosis affects three women for every one man. French scientists are studying the role of the sex hormones in order to better understand this discrepancy.

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News • Medical engineering

‘Smart' bandages monitor wounds and provide targeted treatment

A new kind of smart bandage developed at Caltech may make treatment of chronic wounds - for example caused by diabetes - easier, more effective, and less expensive.

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News • Promising results pave way for trial

A vaccine against allergic asthma: reseachers report new milestone

French scientists are developing and testing a new vaccine to combat allergic asthma. Their latest study results pave the way for the organization of a clinical trial.

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News • Regenerative medicine

Tapping into a tumor's power to heal non-healing wounds

Scientists have discovered a way to train healthy immune cells to acquire the skills of some tumor cells for a good purpose: to accelerate diabetic wound healing.

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News • UK study draws connection

Asthma: end of Covid-19 restrictions doubled risk of severe attacks

Adults with asthma had, at one point, an approximately doubled risk of a severe asthma attack after Covid-19 restrictions were relaxed in the UK, according to new research.

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News • Multiple biomarker detection

Smart bandage shows promise for chronic wound monitoring

A research team led by Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering and Institute for Health Innovation & Technology (iHealthtech), in collaboration with clinical partners from Singapore General Hospital, has developed a smart wearable sensor that can conduct real-time, point-of-care assessment of chronic wounds wirelessly…

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News • Headache

Chronic migraine: potential novel treatment discovered

By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine. Amynah Pradhan, associate professor of psychiatry at the University of Illinois Chicago, is the senior author of the study, whose goal was to identify a new mechanism of chronic migraine, and propose a cellular pathway for migraine therapies. The study, “Neuronal…

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News • Biochemistry

Potential trigger of Crohn’s disease found

Potentially game-changing research led by McMaster University scientists may finally bring relief to millions of people worldwide living with Crohn’s disease. Investigator Brian Coombes said his team identified a strain of adherent-invasive E-coli (AIEC) that is strongly implicated in the condition and is often found in the intestines of people with Crohn’s disease. “If you examine the gut…

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News • Profiling the coronavirus

Risk factors for severe and fatal COVID-19 cases identified

Age, male sex, obesity, and underlying illness have emerged as risk factors for severe and fatal cases of COVID-19 in the UK, according to the largest cohort study to date published by The BMJ. As the largest prospective observational study reported worldwide to date, it provides a comprehensive picture of the characteristics of patients hospitalised in the UK with COVID-19 and their outcomes.…

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News • COPD, asthma and more

Deaths and disability due to lung diseases on the rise

There has been an increase in deaths and disability due to chronic respiratory (lung) diseases over the past three decades, finds an analysis of data from 195 countries published by The BMJ. The poorest regions of the world had the greatest disease burden. Ageing and risk factors including smoking, environmental pollution, and body weight also play a key role, say the researchers. Chronic…

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News • Gastroenterology

Crohn's disease linked to increased risk of colorectal cancer

Researchers from Karolinska Institutet, Örebro University and Aarhus University, Denmark, have published the largest study to date on the risk of colorectal cancer in Crohn's disease. The article is published in the journal The Lancet Gastroenterology Hepatology. Crohn's disease is a chronic inflammatory bowel disease (IBD). Several previous studies have reported an increased risk of colorectal…

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News • Boosting the microbiome

A vaccine against chronic inflammatory diseases

In animals, a vaccine modifying the composition and function of the gut microbiota provides protection against the onset of chronic inflammatory bowel diseases and certain metabolic disorders, such as diabetes and obesity. This research was conducted by the team of Benoît Chassaing, Inserm researcher at Institut Cochin (Inserm/CNRS/Université de Paris), whose initial findings have been…

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News • Multiple sclerosis and the psyche

Depression speeds up appearance of MS symptoms

People with multiple sclerosis (MS) who also have depression are more likely to suffer debilitating symptoms early than people with MS who are not depressed, according to a study at Karolinska Institutet in Sweden that is published in the journal Neurology. The findings highlight the need for early recognition and treatment of depressive symptoms in patients with MS. More than 2 million people…

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Interview • Chronic inflammations

GATA-3: 'Switching off' allergies and asthma

Chronic inflammatory diseases, such as allergies and asthma, are not only an acute problem but also a major research and prevention challenge. We spoke with Professor Harald Renz, Director of the Institute for Laboratory Medicine at the University Hospital Gießen/Marburg, Germany, and discussed the major reason for increases in the number of these widespread diseases.

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News • Neural network approach to ECG

AI detects heart failure from a single heartbeat

Researchers have developed a neural network approach that can accurately identify congestive heart failure with 100% accuracy through analysis of just one raw electrocardiogram (ECG) heartbeat, a new study reports. Congestive heart failure (CHF) is a chronic progressive condition that affects the pumping power of the heart muscles. Associated with high prevalence, significant mortality rates and…

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News • Chronic Liver Disease

Study confirms clinical benefit of ShearWave Elastography

SuperSonic Imagine announces that a multicenter retrospective study conducted in Europe and China, has confirmed the clinical utility of ShearWave Elastography in patients with chronic liver disease, the first results of which were presented at the International Liver Congress (ILC 2019). The objective of this study was to evaluate the diagnostic value of ShearWave Elastography (SWE) in the…

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News • Double danger

MS patients at a greater risk of cancer, new study suggests

New results of a 65-year follow-up study of nearly 7,000 Norwegian patients with Multiple Sclerosis (MS) suggest that patients may have a greater overall risk of developing cancer than the general population, with an especially high risk of cancer in respiratory organs, urinary organs and the central nervous system. Presented at the 5th European Academy of Neurology (EAN) Congress in Oslo,…

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News • More than a symptom

Chronic pain: a real disease after all?

For the first time ever, chronic pain will be classified as a diagnosis in line with other diseases when the World Health Organization (WHO) approves the next catalogue of recognised diseases in May. According to Professor Peter Svensson from the Department of Dentistry and Oral Health, this is very significant for the approx. 20% of the population who suffer from chronic pain. Working with top…

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News • Building a risk profile

Audiologists seek genetic link to tinnitus

Tinnitus, more commonly known as ringing in the ears, is a serious audiological and neurological condition affecting nearly 50 million Americans. Noise and music exposure are the predominant environmental risk factors for tinnitus. There is no known cure, and there are no FDA-approved medications developed specifically to treat it. The fact is, tinnitus is very common but not well understood. A…

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