Breast cancer

Breast cancer (breast carcinoma; often abbreviated as BRCA) is the most common cancer in women in many countries and the cancer with the highest mortality rate. The diagnostic and therapeutic options for breast cancer are correspondingly diverse. Read more about the latest research, diagnoses and treatments.

Interview • AI, modern mammography, and more

Breast imaging breakthroughs presented at EUSOBI 2024

Minimally invasive surgical interventions, innovative imaging and the use of AI: At the upcoming EUSOBI congress in Lisbon, experts present and discuss the latest advances in breast imaging. We spoke…

News • Groundwork for new treatments

Fibrosis a prognostic biomarker for HER2-negative breast cancer

A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.

News • Breast cancer detection

Decade of DBT: 10-year study shows benefits of tomosynthesis

Evidence of the superiority of tomosynthesis for breast cancer detection is stacking up, with new results from a 10-year study further demonstrating the 3D imaging technique's benefits.

News • Research on BRCA recurrence

Breastfeeding after breast cancer treatment is safe, studies find

Two international studies presented at the ESMO Congress 2024 show no increase in recurrence or new breast cancers in women who breastfeed after being treated for breast cancer.

News • Breast cancer screening

The emotional impact of false positive mammograms

Mammography can lead to “false positives,” meaning they do not result in a breast cancer diagnosis. This may discourage some women from future screenings, according to a new study.

News • Recurrence timeframe analysis

Breast cancer radiotherapy: new insights on duration of protective effect

After breast cancer surgery, radiotherapy helps prevent the cancer from returning. However, this protection does not last forever. A long-term study shows the duration of the treatment's benefits.

News • Tumor assessment via chromatin imaging

From DCIS to IDC: AI identifies breast cancer stages

Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.

News • Electronic prompt in the EHR

‘Nudging’ surgeons away from breast cancer overtreatment

Sentinel lymph node biopsies can help detect breast cancer – but not every patient benefits from the procedure. New research finds that a simple EHR prompt can prevent unnecessary surgery.

News • Tumour infiltrating lymphocyte measurement

Breast cancer: AI tool predicts which DCIS cases become invasive

Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.

News • Taxane-induced peripheral neuropathy

New tool predicts nerve damage after breast cancer chemotherapy

Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.

News • Research on physical conditions

Exploring the link between obesity and cancer risk

Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.

News • Vital mechanism discovered

Promising approach to prevent breast cancer recurrence

Finnish researchers discovered a mechanism that wakes up dormant breast cancer cells and demonstrated that preventing the mechanism can significantly improve treatment outcomes in experimental models.

Article • Addressing diagnostic backlogs

Harnessing the power of AI for women's health

Although the Covid-19 pandemic is behind us, healthcare facilities continue to experience workflow challenges and resource constraints impacting women’s health and a patient’s ability to receive a timely diagnosis. Clinical specialties like breast radiology and cytology are especially susceptible to these issues and continue to experience backlogs, which impact their ability to deliver timely…

News • Impact on mammography performance

Breast cancer screening: better detection, fewer false positives with AI

Using artificial intelligence (AI), breast radiologists in Denmark have improved breast cancer screening performance and reduced the rate of false-positive findings.

News • Impact of patient characteristics

Breast cancer AI: unequal performance across ethnicities and age groups

Current AI systems for detecting breast cancer from mammography exams are more likely to produce false-positive results in black women and older patients, a new study finds.

News • Research on biomechanics

Tumour 'softness' can drive aggressiveness of breast cancer

Researchers have discovered how the mechanical properties of tumours - their softness, for example - can prime cancer cells to better survive their spread to other organs.

Article • Lesion detection and mammographic texture analysis

Dual AI model to optimize breast cancer risk assessment

A team of Danish and Dutch researchers has combined an AI diagnostic tool with a mammographic texture model to improve the assessment of short- and long-term breast cancer risk. This new approach represents a significant step forward in refining the ability to predict the complexities of breast cancer risk.

News • Omitting axillary lymph node removal

Breast cancer trial explores benefits of less extensive surgery

A new trial could pave the way for more gentle surgery of breast cancer: The researchers explore the possibility of sparing the lymph nodes in the armpit - even if metastases are already present.

News • BRCA1 and BRCA2 malfunctions

Targeting 'exhausted' immune cells to prevent breast cancer

A study found immune cells in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of ‘exhaustion’. This opens new possibilities for cancer prevention.

News • 3D mammography

Trial shows benefits of digital breast tomosynthesis in breast cancer screening

A clinical trial has revealed the effectiveness of '3D mammography' in reducing by almost half the incidence of interval breast cancer appearing between two rounds of screening.

News • Promising study

Pre-operative PET-MRI to improve breast cancer treatment

A combination of PET and MR imaging could help doctors spot signs that breast cancer is beginning to spread in a patient. This insight can then be used to adapt treatment strategies.

News • Tumor proliferation insights

Computational model simulates biomechanical growth of breast cancer

A research team created a computational model that simulates the invasion of cancer cells in breast tumors on a biomechanical level. This could help predict the evolution of breast cancer in patients.

News • Characterization of cancer relevant genes

Breast cancer: Researchers take a deep dive into cell lines

Biochemists and bioinformaticians from the Leibniz Institute DSMZ have extensively characterized the molecular properties of the breast cancer cell lines from the institute's collection.

Article • Key findings of latest survey

Women’s health: solutions for a growing problem

Awareness of the importance of women’s health is on the rise, but many challenges remain: At ECR 2024 in Vienna, we spoke with Hologic about their continued evaluation of healthcare efforts for women. At the congress, the company also shared how AI could be used to mitigate the effects of medical staff shortage.

News • Women's health imaging

Breast cancer: MRI surveillance reduces mortality in BRCA1 high-risk women

An international study has revealed that MRI monitoring in women with mutations in the BRCA1 genes significantly reduces breast cancer mortality without the need for preventive mastectomy.

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