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Breast cancer

Breast cancer (breast carcinoma; often abbreviated as BRCA) is the most common cancer in women in many countries and the cancer with the highest mortality rate. The diagnostic and therapeutic options for breast cancer are correspondingly diverse. Read more about the latest research, diagnoses and treatments.

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Organoid research

Structure formation in mini-organs

Many of the organ systems found in animals exhibit highly complex structures, which are essential for their various functions. How such structures develop during embryonic development is a central…

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Histological grading assistance

AI improves precision in breast cancer diagnosis

Researchers at Karolinska Institutet have developed an AI-based tool that improves the diagnosis of breast cancer tumours and the ability to predict the risk of recurrence. The greater diagnostic…

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Additional costs that pay off

For women with dense breasts, MRIs are cost effective for detecting breast cancer

New research indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography. About 10% of women have extremely dense breasts, and current…

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Promising algorithm

AI tool improves breast cancer imaging accuracy

A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows. When tested separately on 44,755…

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Insight report

More screening and secondary prevention needed

For World Patient Safety Day, Health First Europe (HFE) published a comprehensive insight report on five disease areas that affect millions of European citizens each year and how the European Union…

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DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that…

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Classifying subtypes

Breast cancer ‘ecotypes’ could lead to more personalised treatment

A team led by the Garvan Institute of Medical Research has revealed a new approach for classifying breast cancer subtypes based on their cell profile, which could help personalise treatments for patients. By analysing breast cancer biopsies from patients at Sydney hospitals, the researchers revealed more than 50 distinct cancer, immune and connective cell types and states, which could assign…

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Neoadjuvant chemotherapy

Breast cancer: New test predicts therapy success

In a collaboration with the Faculty of Statistics at TU Dortmund and the University Medical Center in Mainz, a research team at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) has developed a test that can be used to predict the success of therapy for breast cancer. Breast cancer is one of the most common tumour diseases worldwide. One in eight women will…

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Workflow optimisation

The potential of AI in breast imaging efficiency

The contribution of Artificial intelligence (AI) has great potential in breast imaging efficiency, Professor Linda Moy MD told attendees at the 2021 Society of Breast Imaging/American College of Radiology (SBI/ACR) Breast Imaging Symposium this April. AI models for breast imaging have focused mainly on the diagnostic classification and detection of breast cancer.

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Mammacarcinoma study

Breast cancer: finishing treatment soon after diagnosis increases survival

Research from Cleveland Clinic in the U.S. and Cleveland Clinic Abu Dhabi in the U.A.E. has found a decrease in patient survival rates when treatment options – surgery, chemotherapy and radiation – are completed more than 38 weeks from the time of diagnosis. The observational study, which included more than 28,000 breast cancer patients registered in the American National Cancer Database, is…

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Oncology early detection tool

Blood test for 50+ types of cancer promising for screening

Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher risk of the disease, including patients aged 50 years or older, without symptoms. In a paper published in the cancer journal Annals of Oncology, researchers report that the test accurately detected…

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Campaign to reprioritise breast health

Breast cancer: "Screening routine" to combat Covid-related backlog

One of the negative impacts of the coronavirus pandemic has been the suspension or postponement of many cancer screening services. Each year, these services help prevent and detect the presence of cancer at an early stage; timely diagnosis and care are crucial in preventing the spread of cancer. The National Screening Observatory has confirmed this, reporting alarming statistics: during the first…

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Mammography support

AI solution may reduce interval breast cancer rates

Medical technology company iCAD, Inc. announced that ProFound AI for 2D Mammography might notably reduce the risk of interval breast cancer, according to a new retrospective analysis. The aim of the study was to determine if adding AI to reading mammography as a supportive tool may help in decreasing the interval cancer rate in population-based organized mammography screening programs in Germany.

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Promising study results

Electromagnetic fields hinder spread of breast cancer

Electricity may slow – and in some cases, stop – the speed at which breast cancer cells spread through the body, a new study indicates. The research also found that electromagnetic fields might hinder the amount of breast cancer cells that spread. The findings, published recently in the journal Bioelectricity, suggest that electromagnetic fields might be a useful tool in fighting cancers that…

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Breast cancer diagnostics

New system to make AI diagnosis explainable

Researchers at TU Berlin and Charité – Universitätsmedizin Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI). Two further developments make this system unique: For the first time, morphological, molecular and histological data are integrated in a single analysis. Secondly, the system…

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AI tool might reduce surgery

Managing cancer-questionable breast lesions

The management of biopsied breast lesions that are diagnosed as abnormal but are not definitively malignant is challenging and controversial. Treatment ranges from diligent follow-up, with imaging and subsequent biopsy, to surgical excision. Researchers at the Medical University of Vienna (Medizinische Universität Wien), Austria, have developed and validated a software algorithm designed to…

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The iCAIRD project

AI to aid Scottish breast screening

Implementation of artificial intelligence into Scotland’s national breast screening service is moving closer following an initial success with a trial project. While Scotland’s breast screening trial has delivered highs and lows, significant hurdles have been overcome in terms of approvals, governance and patient acceptance.

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Superior in identifying cancers in symptomatic younger women

Breast cancer detection: advantage DBT

Digital breast tomosynthesis (DBT) increases detection of breast cancer in symptomatic women under the age of 60, especially in dense breasts. A large, multi-institutional study conducted in the United Kingdom comparing the sensitivity of full-field digital mammography (FFDM), DBT, and FFDM plus DBT supports findings of two similar published studies, both conducted in China in the same time frame.

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