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Breast cancer

Breast cancer (breast carcinoma; often abbreviated as BRCA) is the most common cancer in women in many countries and the cancer with the highest mortality rate. The diagnostic and therapeutic options for breast cancer are correspondingly diverse. Read more about the latest research, diagnoses and treatments.

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Advances in cancer risk assessment and prevention

French oncologists pick up the pace after pandemic time-out

Personalised screening, data-driven aproaches: In a dedicated press conference in Paris, French oncologists presented promising research that might bring hope for many cancer patients.

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Companion treatment

Magnetic therapy to enhance breast cancer chemotherapy

A team of researchers from Singapore has developed a novel magnetic therapy that serves as an effective companion therapy to chemotherapy to enhance treatment outcome for breast cancer.

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Tumour plasticity

Why breast cancer metastases spread to the bone

A protein vital in determining the organs affected by metastasis has been identified by Swiss researchers. This could lead to the development of therapeutic approaches to suppress metastasis.

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Mammography evaluation

Breast cancer screening: AI shows promise

A major new study shows that artificial intelligence (AI) is a promising tool for breast cancer detection in screening mammography programs.

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cfDNA to assess tumours

Recurrent breast cancer: liquid biopsy improves detection, monitoring

Liquid biopsy performed on serum samples taken from breast cancer patients can provide increasingly accurate information on progression and enable earlier detection of recurrence.

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Cancer imaging

MRI 2.0 lights up cancerous tissue

Synthetic correlated diffusion makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time.

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Conducting diagnostics

Detecting breast cancer via electrical currents in the skin

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation. While the risk of getting breast cancer is higher for older people, it can strike at any age. Studies show that 5% to 7% of females with breast cancer…

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NGS solution

Using liquid biopsy to detect recurrent breast cancer earlier

An innovative collaboration has been formed in the UK between academic researchers and industry to develop a rapid integrated liquid biopsy platform for early detection of recurrent breast cancer. Breast cancer specialists Professor Charles Coombes, who is Professor of Medical Oncology at Imperial College London (ICL), and Professor Jacqui Shaw, Head of the Department of Genetics and Genome…

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Metastasis research

Study reveals risk of breast cancer spreading to other parts of the body

The risk of early breast cancer spreading to another part of the body ranges from 6% to 22%, according to the first results of a large and detailed global study of metastatic breast cancer presented at the Advanced Breast Cancer Sixth International Consensus Conference (ABC 6). The study also shows that certain women face a higher risk than others, including women diagnosed with breast cancer at…

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Sponsored • Breast imaging congress

EUSOBI 2021: A turning point in women’s health

The breast imaging field plays a critical role in women’s health and wellbeing around the globe. Bringing together experts, leaders and innovators from across the breast imaging landscape, the 2021 European Society of Breast Imaging (EUSOBI) Congress comes at a crucial time and represents a pivotal opportunity for the industry as a whole. Taking place online from 4-28 October, 2021, the virtual…

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Prevention of triple-negative BRCA

Breast cancer vaccine: clinical trial started

Researchers from Cleveland Clinic have opened a novel study for a vaccine aimed at eventually preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. This phase I trial is designed to determine the maximum tolerated dose of the vaccine in patients with early-stage triple-negative breast cancer and to characterize and optimize the body’s immune response. The…

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NGS-based diagnostics

Collaboration on early detection of recurrent breast cancer

Together with Imperial College London (‘Imperial’), molecular diagnostics company DNAe has been awarded a UK Knowledge Transfer Partnership (KTP) by Innovate UK to support development of its next generation sequencing (NGS)-based diagnostic platform for use in cancer monitoring. The KTP program connects innovative businesses with academic experts who can help them deliver their ideas. This…

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Organoid research

Structure formation in mini-organs

Many of the organ systems found in animals exhibit highly complex structures, which are essential for their various functions. How such structures develop during embryonic development is a central question in biology. Physicists led by Erwin Frey (Professor of Statistical and Biological Physics at LMU Munich) and Andreas Bausch (Professor of Cellular Biophysics at the Technical University of…

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Histological grading assistance

AI improves precision in breast cancer diagnosis

Researchers at Karolinska Institutet have developed an AI-based tool that improves the diagnosis of breast cancer tumours and the ability to predict the risk of recurrence. The greater diagnostic precision can lead to more personalised treatment for the large group of breast cancer patients with intermediate risk tumours. The results are published in the scientific journal Annals of Oncology.

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Additional costs that pay off

For women with dense breasts, MRIs are cost effective for detecting breast cancer

New research indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography. About 10% of women have extremely dense breasts, and current mammography screening guidelines do not recommend additional imaging tests unless there is a strong family history or genetic risk for breast cancer. Such women face two problems. They have increased…

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Promising algorithm

AI tool improves breast cancer imaging accuracy

A computer program trained to see patterns among thousands of breast ultrasound images can aid physicians in accurately diagnosing breast cancer, a new study shows. When tested separately on 44,755 already completed ultrasound exams, the artificial intelligence (AI) tool improved radiologists’ ability to correctly identify the disease by 37 percent and reduced the number of tissue samples, or…

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DNA damage causes AML

Cancer chemotherapy side-effects on blood cell development

By analysing secondary acute myeloid leukaemias, researchers at the Institute for Research in Biomedicine (IRB) Barcelona have detected mutations caused by platinum-based chemotherapies in cells that were healthy at the time of treatment. Treatment with chemotherapies influences the development of blood cells, favouring clonal hematopoiesis from cells with pre-existing mutations. The study has…

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