Breast cancer

Breast cancer (breast carcinoma; often abbreviated as BRCA) is the most common cancer in women in many countries and the cancer with the highest mortality rate. The diagnostic and therapeutic options for breast cancer are correspondingly diverse. Read more about the latest research, diagnoses and treatments.

News • Research identifies information barriers

‘Top surgery’ and breast cancer risk: Towards informed decision-making

Transgender and gender diverse individuals undergoing gender-affirming mastectomy (‘top surgery’) often lack information on how the procedure will affect breast cancer risk, a new study finds.

News • Prediction model

Building a “calculator” for breast cancer risk

A promising predictive model could help women calculate their personal risk for breast cancer, based on non-genetic, genetic and mammographic risk factors, and greatly improve early detection efforts.

News • Commensal dysbiosis

Study links bile acid buildup to breast cancer metastasis

A buildup of bile acids caused by an unhealthy gut can drive breast cancer to other parts of the body, new research reveals. The findings could open the door to new ways to prevent cancer metastasis.

News • Operator-independent breast cancer screening

Portable ultrasound system takes the hard part out of breast imaging

A new portable ultrasound system could make breast imaging more accessible. The device generates high-res, 3D images of breast tissue, requires no expertise to operate and could be used at home.

News • Longitudinal AI analysis

Deep learning predicts breast cancer risk from changes in mammograms

AI models can now assess breast cancer risk directly from changes in screening mammograms over time, a new study shows. This opens the door to a new era of dynamic breast cancer risk assessment.

News • OPTIMA trial results

Gene test could safely spare breast cancer patients of chemotherapy

Many people with breast cancer can avoid chemotherapy with a gene test, potentially sparing them side effects without increasing the risk of the cancer returning, a clinical trial has found.

News • Metabolic health

Obesity helps breast cancer become invasive

Obesity may change how early-stage breast cancer becomes invasive, according to a new study. The findings could help improve physicians’ ability to predict and treat the disease.

News • Sex-specific effects of bariatric surgery

Why weight-loss surgery lowers cancer risk in women

Substantial and sustained weight-loss after bariatric surgery has been linked to a reduced risk of cancer and cancer-related death, mainly in women. Two new studies now provide clues as to why.

News • Promising results for low-risk women

Radiotherapy advances may let breast cancer patients skip surgery

Due to advances in radiation therapy, some breast cancer patients may be able to omit surgery following ablative radiation, according to new results of a Phase 2 trial.

News • SBRT for longer control

Targeted radiotherapy shows promise against metastatic breast cancer

Once breast cancer begins to metastasise, it generally becomes harder to treat and survival rates are lower. Now, researchers present a new, targeted treatment approach using SBRT radiotherapy.

News • Mammary tumorigenesis

New marker identifies which breast lesions will progress to cancer

Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.

News • Single-cell spatial atlas

Breast cancer: map explores role of aging tissue

As women age, their breast tissue goes through major changes, with the most dramatic changes at menopause, but also during pregnancy and childbirth. A map reveals the impact on breast cancer.

News • Treatment de-escalation

Patient-tailored radiotherapy effectively prevents breast cancer recurrence

The chances of breast cancer recurring remain very low when patients are treated with radiotherapy that is tailored to their individual risk following chemotherapy and surgery, new study results find.

News • Triple-negative breast cancer

TNBC can become treatment-resistant in more ways than one

About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy, significantly reducing the chances of survival. Researchers found there is more than one way this can happen.

Article • Support for clinicians beyond initial diagnosis

Enhancing breast imaging with AI

Artificial intelligence has a critical role to play in supporting clinicians beyond the initial breast cancer diagnosis. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, Professor Gerald Lip outlined how AI can enhance the performance of modalities such as ultrasound and MRI in supporting clinicians as they plan and deliver treatment for patients.

News • Study shows stage-specific outcomes

Screening increases survival rate – even in advanced breast cancer

Study shows women with stage IV breast cancer detected through screening have a 60% chance of survival ten years after diagnosis – compared to under 20% for those not detected through screening.

News • Proof-of-principle study

Ultra low-field MRI shows promise for breast cancer screening

New research shows that using ultra-low field (ULF) MRI for breast imaging could offer an alternative to existing breast cancer screening methods and may reduce barriers to screening.

Article • The “invisible” population

Breast screening blind spot: Why transgender patients are falling through the cracks

Transgender patients are largely invisible in breast cancer screening statistics – and many never receive an invitation to participate in screening programmes. Guidelines exist, but awareness among referring physicians remains low. Experts say radiology departments are best positioned to lead the change by creating inclusive environments and actively reaching out to this underserved population.…

News • Low-power architecture

Portable ultrasound sensor to enable earlier detection of breast cancer

MIT researchers have developed a miniaturized ultrasound system that could make it easier for breast ultrasounds to be performed more often, either at home or at a doctor’s office.

Article • Implementation of clinical artificial intelligence

One AI, one radiologist: How a Swedish hospital beat breast screening backlogs

When radiologists at Stockholm's Capio Sankt Görans Hospital began working evenings and weekends to clear mounting backlogs, it became clear that something had to change. The solution? Replacing one of the two radiologists traditionally assigned to read breast cancer screenings with artificial intelligence (AI). The results: fewer false positives, more cancers detected, and radiologists…

News • Acellular dermal matrix for breast reconstruction

Injectable breast ‘implant’ as alternative to surgery

Researchers have developed a prototype injectable paste that could help restore breast volume after tumor removal, with less scarring and shorter healing time than current options.

Article • Advancing risk stratification

AI in breast cancer screening: From mammograms to personalised risk prediction

Artificial intelligence is reshaping how clinicians identify women at higher risk of breast cancer – and may soon guide decisions on supplemental screening and treatment. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting in Aberdeen, Scotland, two experts presented their latest findings on AI-driven risk stratification and response prediction.

News • Genetic risk-based approach

Enhancing breast cancer screening to save young women’s lives

Breast cancer screening for women under 50 isn't cost-effective – yet 1 in 5 diagnoses occurs in this age group. A new study suggests a personalised approach that could change this equation.

Article • Overlooked and underserved populations

Breast imaging for male and transgender patients: bridging the knowledge gap

Breast imaging for male and transgender patients remains an under-researched field with significant gaps in guidelines and clinical practice. At the European Society of Breast Imaging (EUSOBI) annual scientific meeting, experts presented findings from a pan-European survey on male breast imaging and announced plans for a similar initiative focusing on transgender patients.

News • Lung cancer CT notification

Breast cancer: Keep CALM – and coordinate your screenings

Many women over 50 schedule mammograms for breast cancer but miss out on CT lung cancer screenings they're also eligible for. Targeted outreach coul help change this, a new study shows.

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