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Chemotherapy

Chemotherapy is used against various cancers and is often consideres as a last resort – especially if the cancer has metastasised. Since chemotherapy agents can cause severe side effects, research aims to make treatment more tolerable.

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News • Reducing chemotherapy side effects

Trapping cancer cells in molecular 'cages'

Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.

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News • Circadian-based therapeutic strategies

Cancer drugs more effective when the time-of-day is right, study finds

The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.

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News • Combined chemo and radiotherapy

Promising treatment for rectal cancer to avoid surgery

When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.

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News • Taxane-induced peripheral neuropathy

New tool predicts nerve damage after breast cancer chemotherapy

Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.

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News • The role of tissue stiffness

Pancreatic cancer: new approach could reverse chemo resistance

Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.

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News • Iontronic technology

Slowly but steady gets the brain tumour

Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.

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Article • Five-year EU project to avoid heart damage in oncology patients

Cardiac collaterals in breast cancer therapy

Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC 2023 cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…

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