Chemotherapy is used against various cancers and is often consideres as a last resort – especially if the cancer has metastasised. Since chemotherapy agents can cause severe side effects, research aims to make treatment more tolerable.
A new study measured how well breast cancer patients’ tumour ‘explants’ respond to chemotherapy or HER2 antibody therapy in the laboratory. This could help improve clinical outcomes.
Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.
A premiere that brings hope for fertility restoration to men who underwent chemotherapy during childhood: Researchers reintroduced cryopreserved immature testicular tissue taken 16 years prior.
Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.
Treating patients with Hodgkin lymphoma with a different form of chemotherapy shows promise to reduce severe side effects, shorten hospital time and increase likelihood of recovering fertility.
Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.
Researchers propose the use of molecular ‘cages’ (made of pseudopeptides) to selectively eliminate cancer cells in acidic microenvironments. This could help reduce side effects from chemotherapy.
The time of day can be an important aspect to consider for cancer therapy. Researchers from Charité are developing new methods to use the internal clock inside tumor cells to optimize treatments.
When a person is diagnosed with rectal cancer, part of the bowel is often removed, often resulting in the need for a stoma or problems with bowel control. A new therapy could help avoid this surgery.
Researchers have developed a tool that can predict the risk level for side effects in the nervous system of women treated for breast cancer using taxanes. This could help adapt treatment.
Researchers at Stanford have demonstrated that conditions in the matrix surrounding pancreatic cancer cells impact whether those cells respond to chemotherapy.
Researchers demonstrated how the growth of malignant brain tumours can be greatly decreased by using iontronic technology to continuously administer low doses of cancer drugs.
Chemotherapy kills cancer cells – but how? New research suggests that the mechanisms are different than previously understood. The finding will have implications for future cancer treatments.
Blood cancer cells can remain in the blood of AML patients, even after chemotherapy seemed successful. Testing for these residuals before blood cell donation is a vital precaution, a new study finds.
US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.
Researchers have now shown that a noninvasive treatment that stimulates gamma frequency brain waves may hold promise for treating memory impairment and other cognitive effects of chemotherapy.
Chemotherapy can be toxic to heart cells. To help protect the hearts of cancer patients, Cedars-Sinai investigators have created a three-dimensional “heart-on-a-chip” to evaluate drug safety.
Chemotherapy against cancer can lead to the generation of senescent tumour cells, which can help the tumour survive. A new immunotherapy approach to eliminate these cells shows promise in animal models.
New trial results suggest that a short course of induction chemotherapy prior to chemoradiation could reduce the rate of relapse and death among patients with locally advanced cervical cancer.
