Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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Labs processing 2,000 to 5,000 tests a day

Workflow automation solutions for mid-volume laboratories

Clinical diagnostics company Beckman Coulter announced the European launch of the DxA 5000 Fit, a workflow-automation solution designed to fit into medium-sized labs that run fewer than 5,000 tests a…

Products of the Month

Enhance your Microscopy Workflow

Did you know that changing microscopy camera can make a real difference to your microscopy workflow? Packed full of smart features to make your imaging faster and easier, Olympus’ new DP23 and DP28…

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Mass spectrometry analysis

Skin swabs can detect Covid-19

Skin swab samples analysed using mass spectrometry could be used to detect Covid-19 in patients, according to research conducted at the University of Surrey in the UK. Current Covid-19 testing is via a polymerase chain reaction (PCR) test, which involves taking a swab of the back of the throat and inside the nose, but the team from Surrey - working with Frimley NHS Trust and the Universities of Manchester and Leicester - have used sebum samples from the outer layers of skin (stratum corneum) to identify the presence of Covid-19. They collected samples from 67 hospitalised patients - 30 who had tested positive for Covid-19 and 37 who had tested negative – by swabbing skin between the shoulder blades. It is an area of the body which is rich in sebum, the oily, waxy substance produced by…

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Product of the Month

The gentle touch

The brand-new Vacuette® Evoprotect Safety Blood Collection Set is the next evolution of safety.

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Tau pathology in the brain

Defining the 4 subtypes of Alzheimer's

Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns…

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Coronavirus research

'Covid-19 atlas' uncovers differing immune responses in asymptomatic versus severe cases

The largest study of its kind in the UK has identified differences in the immune response to Covid-19 between people with no symptoms, compared to those suffering a more serious reaction to the…

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dPCR and HSAFM

Low-cost technique for missed genetic mutations

A new low-cost method targeting genetic mutations often missed by existing diagnostic approaches has been developed. Researchers at Virginia Commonwealth University (VCU) in the United States noted…

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Precise, affordable, and portable

A health testing platform that consolidates multimodal and multiplex testing to one device

Fluxergy envisions that a fully articulated democratized testing health system has the potential to reduce the likelihood and the ultimate severity of pandemics like Covid-19. Our mission is to…

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After overcoming a Corona infection

Covid-19: Study on long-term antibody protection

Does overcoming a SARS-CoV-2 infection protect against reinfection? The “Rhineland Study”, a population-based study conducted by DZNE in the Bonn area, is now providing new findings in this…

Products from Labbook

Greiner – Vacuette EDTA Tube

Blood Cell Counter

Greiner – Vacuette EDTA Tube

Greiner Bio-One
Beckman Coulter – Remisol Advance

LIS, Middleware, POCT

Beckman Coulter – Remisol Advance

Beckman Coulter, Inc.
Siemens Healthineers – epoc Blood Analysis System

Blood Gases, Electrolytes, Oximetry

Siemens Healthineers – epoc Blood Analysis System

Siemens Healthineers
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POC Troponin I analysis

Expediting the diagnosis of heart attack

Siemens Healthineers announced the company's Atellica VTLi Patient-Side Immunoassay Analyzer has obtained CE mark and is expected to be available later this spring. The Atellica VTLi analyzer provides lab standard, high-sensitivity cardiac troponin I (hs-cTnI) test results to clinicians in eight minutes using a patient's fingerstick blood sample. With this industry first technology, Siemens…

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Reverse genetics system

SARS-CoV-2: An easier and quicker way to analyse mutations

SARS-CoV-2 is the virus responsible for the Covid-19 pandemic. We know that mutations in the genome of SARS-CoV-2 have occurred and spread, but what effect do those mutations have? Current methods for studying mutations in the SARS-CoV-2 genome are very complicated and time-consuming because coronaviruses have large genomes, but now a team from Osaka University and Hokkaido University have…

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Biomarker research

"Jumping" genes might protect against AML and other blood cancers

New research has uncovered a surprising role for so-called “jumping” genes that are a source of genetic mutations responsible for a number of human diseases. In the new study from Children’s Medical Center Research Institute at UT Southwestern (CRI), scientists made the unexpected discovery that these DNA sequences, also known as transposons, can protect against certain blood cancers. These…

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Protection from bacteria, fungi, viruses

Antimicrobial technologies – how do they work?

Antimicrobial technologies such as coatings and textiles containing silver and copper are helping people during the Covid-19 pandemic by ensuring that whatever they touch, whether that is a door handle or their own mask, is free from live SARS-CoV-2 particles. But how exactly do these antimicrobial technologies work? How can a silver, copper or even polymeric coating kill microorganisms such as…

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Diagnostics team-up

Cooperation to accelerate adoption of AI-powered digital pathology

Royal Philips and Ibex Medical Analytics announced a strategic collaboration to jointly promote their digital pathology and AI solutions to hospitals, health networks and pathology labs worldwide. The combination of Philips digital pathology solution (Philips IntelliSite Pathology Solution) and Ibex’s Galen AI-powered cancer diagnostics platform, currently in clinical use in Europe and the…

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Bioengineering

Producing transplantable livers in the laboratory

Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory. The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of…

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SARS-CoV-2 detection and sequencing

'Nirvana': Fast, portable test diagnoses Covid-19, tracks variants

Clinicians using a new viral screening test can not only diagnose Covid-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruses—like influenza—that might be mistaken for the coronavirus. At the same time, they can sequence the virus, providing valuable information on the spread of Covid-19 mutations and variants. The new test, dubbed…

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Biochemistry

Potential trigger of Crohn’s disease found

Potentially game-changing research led by McMaster University scientists may finally bring relief to millions of people worldwide living with Crohn’s disease. Investigator Brian Coombes said his team identified a strain of adherent-invasive E-coli (AIEC) that is strongly implicated in the condition and is often found in the intestines of people with Crohn’s disease. “If you examine the gut…

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Innovative protein analysis

Cooking an egg in an X-ray beam

A team of scientists has been using the X-ray source PETRA III at the German Electron Synchrotron (DESY) to analyse the structural changes that take place in an egg when you cook it. The work reveals how the proteins in the white of a chicken egg unfold and cross-link with each other to form a solid structure when heated. Their innovative method can be of interest to the food industry as well as…

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The hidden 'fingerprint' of liver cirrhosis

Routine blood tests could be key to stopping 'silent killer'

New research has shown that results of blood tests routinely performed by GPs everywhere contain a hidden fingerprint that can identify people silently developing potentially fatal liver cirrhosis. The researchers have developed an algorithm to detect this fingerprint that could be freely installed on any clinical computer, making this a low-cost way for GPs to carry out large scale screening…

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Digital pathology

AI delivers cervical cancer screening to rural areas of Kenya

Experts from Sweden, Finland and Kenya are using digital microscopy combined with Artificial Intelligence (AI) to deliver a rapid and effective cervical screening service to rural locations in Kenya. The project sees AI and digital diagnostics bridge the gap between low-resource settings and the availability of centralised AI-enhanced expertise and pathology services, located in larger cities in…

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HPV testing advances

Cervical cancer screening: Emerging tech to replace Pap smears

Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives both in developing nations and parts of countries, like the United States, where access to health care may be limited. In Biophysics Reviews, by AIP Publishing, scientists at Massachusetts General Hospital write advances in nanotechnology and computer learning are among the…

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Mass spectrometry

"Protein fingerprint" rapidly identifies Covid-19 biomarkers

Researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have developed a mass spectrometry-based technique capable of measuring samples containing thousands of proteins within just a few minutes. It is faster and cheaper than a conventional blood count. To demonstrate the technique’s potential, the researchers used blood plasma collected from Covid-19 patients.…

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Non-invasive corona breath testing

SpiroNose: The electronic nose that knows about Covid-19

Rapid tests, PCR tests, self-tests… there are many test options to determine contamination with Covid-19. In most this is done by inserting a cotton swab deep into the nose and/or throat to extract some mucus – unpleasant for adults and often a drama for children. Towards the end of 2020, a new system emerged to rule out a Covid-19 contamination. The electronic SpiroNose performs a…

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Professional diabetes management

New handheld analyzer for β-ketone and glucose launched

In vitro diagnostics company EKF Diagnostics announces the global launch of its Stat-Site WB handheld analyzer which delivers β-ketone and glucose measurements from whole blood in seconds. The portable, dual-purpose analyzer is designed for professional use in the management of diabetes patients. The device is used for the quantitative determination of β-ketones (Beta-Hydroxybutyrate or BHB)…

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Laboratory management

Covid-19: Overcoming unprecedented challenges

During a pandemic, the demands for laboratory testing challenge routines in an efficiently run clinical laboratory. Gold standard procedures may need modification, or to be discarded, and the more nimble, resilient and receptive a lab is to change, the better off it could be. Senior managers at ARUP Laboratories in Salt Lake City, Utah, a large clinical reference laboratory that offers over 3,000…

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Analysing molecular composition

Infrared light is key in novel blood test

A new study carried out by a team of laser physicists, molecular biologists and physicians based at LMU Munich and the Max Planck Institute for Quantum Optics has confirmed the temporal stability of the molecular composition of blood in a population of healthy individuals. The data provide a basis for a new method of monitoring the constituents of blood and detecting alterations that reveal…

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Improved Coronavirus detection

Low-cost and fast Covid-19 test uses pool of gargle lavage samples

In order to monitor and contain the spread of SARS-CoV-2 it is necessary to test large numbers of people on a regular basis in decentralized settings. Researchers of the Max Planck Institute for Evolutionary Anthropology and the Hospital St. Georg in Leipzig, Germany, have developed improved protocols for the detection of SARS-CoV-2. The method can detect a positive sample in a pool with 25…

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Product of the Month

Glucose stabilisation right from the beginning

Plasma glucose levels are essential for the evaluation of diabetes mellitus as well as gestational diabetes. Diabetes mellitus is one of the most common metabolic disorders in the world. The breakdown of glucose (glycolysis) in venous blood samples is of great significance in pre-analytics, particularly in relation to the diagnosis of diabetes mellitus and gestational diabetes.

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Multiphoton microscopy gives new insights

Microscopic behaviour of developing breast cells uncovered

An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. This new protocol provides detailed instructions on how to capture hi-res movies of cell movement, division and cooperation, in hard-to-reach regions of breast tissue. The technology – called multiphoton microscopy – uses infrared lasers to illuminate…

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Temperature range from 0°C to -85°C

Ultra-freezers for safe vaccine and sample storage

Temperature control equipment and systems company Lauda is expanding its portfolio with its new Versafreeze product line. This consists of high-quality ultra-freezers which have been optimized for the extreme requirements of deep-freeze storage. Lauda thereby meets the requirements of vaccine producers, pharmaceutical service providers, vaccination centers and universities for the safe storage of…

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