HIV

Researchers date 'hibernating' HIV strains

Researchers have developed a novel way for dating "hibernating" HIV strains, in an advancement for HIV cure research in the province. The HIV cure research confirms that dormant HIV strains…

Testing technology

Vitamin D testing: LC-MS outperforms immunoassays

In recent years, clinicians have increasingly focused on vitamin D deficiency. Studies show that previous reference values – particularly for Vitamin D3 – were most probably set too high. Liquid chromatography with mass spectrometry (LC-MS) can help achieve more precise measurements of vitamin D levels than previously established immunoassay procedures, explains Dr Torsten Binscheck-Domass,…

Oncology

Blood test detects early stage pancreatic cancer

Pancreatic cancer is currently very difficult to detect while it is still resectable. A new blood test developed by researchers at Lund University in Sweden, Herlev Hospital, Knight Cancer Center and…

Rare cancer

A simple blood tests could improve diagnosis of myeloma

A pioneering study into myeloma, a rare cancer, could lead to General Practicianer (GPs) using simple blood tests to improve early diagnosis. The study investigated the best combination of blood…

Infectious disease

Evolution of leading cause of malaria outside of Africa

The genome sequences of ape parasites related to Plasmodium vivax (P. vivax), the main source of mosquito-borne malaria outside Africa, provide insights on the origin and early evolution of the human…

Infections

Reliable point-of-care blood test can help prevent toxoplasmosis

A recent study, performed in Chicago and Rabat, Morocco, found that a novel finger-prick test for infection with the parasite Toxoplasma gondii during pregnancy — and many other potential applications — is 100 percent sensitive and 100 percent specific for detecting the presence of this life-damaging microorganism.

Cancer

'Liquid biopsy' predicts lymphoma therapy success within days

Changes in circulating tumor DNA levels quickly predict how patients with diffuse large B cell lymphoma are responding to therapy, according to a Stanford-led study. Currently, patients wait months…

Genome-editing

New platform could be the next generation of genetic medicine

A scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the…

Diagnostic lab system

DxM MicroScan WalkAway System now available on the market

Beckman Coulter announced commercialization of its DxM MicroScan WalkAway system, a diagnostic solution for bacterial identification and antibiotic susceptibility testing for microbiology…

AACC Disruptive Technology Award

Developers take diagnostics to the patient

Over the last several years, technological advancements have enabled the development of tests that can be performed right where the patient is, whether that’s in a hospital room, primary care…

Acute Coronary Syndrome

Access hsTnI assay rules out ACS in 2 hours

The clinical performance of Beckman Coulter's high-sensitivity troponin I (hsTnI) assay Access hsTnI has been validated in a study. Within 2 hours, the assay delivers an accurate assessment of…

Lab equipment

Atellica Solution gets 'thumbs up' from early adopters

Clinical laboratories are challenged to meet greater testing demands, improve efficiency, and deliver reliable, high-quality results, while facing an increasing shortage of skilled employees and…

Research

First evidence that soot from polluted air is reaching placenta

Evidence of tiny particles of carbon, typically created by burning fossil fuels, has been found in placentas for the first time, in new research presented at the European Respiratory Society…

Fat attenuation index

Biomarker helps to predict coronary inflammation

Researchers at Cleveland Clinic, University of Oxford, and University of Erlangen have identified a novel imaging biomarker – and found it can be used to predict all-cause and cardiac mortality by…

Mobile cMyC analysis

The future POCT heart attack test

Experts report that a new blood test to diagnose heart attacks could be carried out on a hand-held device in the not-too-distant future. The test, devised by a team at Kings College London, uses…

Products from Labbook

Clinical chemistry

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Mass spectrometry

Shimadzu - LCMS-8050 CL

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Microscopy

Olympus - UC90 4K Microscopy

Olympus Europa SE & Co. KG

Sample Processing

SARSTEDT - Decapper DC 1200 / Recapper RC 1200

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Mass spectrometry

Bruker Daltonics - MBT smart

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Lab equipment

Thermo Fisher presents new compact refrigerators for clinical storage

The Thermo Scientific TSG Series of refrigerators maintain optimal cold storage conditions with minimal energy consumption and noise output. They have been specifically developed to address the need of clinical laboratories and patient care facilities for cold storage equipment that enable secure and energy-efficient storage of vaccines, medicines, lab kits and breast milk, while offering quiet…

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Product of the Month

Olympus BX46 microscope – Protecting operators with ergonomics

In microscopy, ergonomics is particularly important as long periods at the microscope put unusually specific constraints on posture. In certain roles, such as in pathology, microscopy forms a significant part of daily activities – sometimes taking up more than 50% of working hours. Protecting operators by preventing injuries is of utmost importance in these routine microscopy roles.

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Risk assessment

Predictive potential of Big Data in the lab

Big Data can be a critical tool in helping clinicians develop advanced patient health risk assessment and stratification models as well as leading to a new level of patient empowerment. Professor Josep Roca outlined the benefits of Big Data in a laboratory context during the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference held in Mannheim, Germany,…

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The EFLM Strategic Conference

Placing the medical lab in a future landscape

The need to ensure that laboratory medicine can meet the future challenges of a rapidly changing healthcare environment sits at the core of an innovative strategic conference for this sector. The agenda of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Strategic Conference in Mannheim (18-19 June) highlighted the challenges, and also outlined areas of discussion to…

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Single nucleotide polymorphism

Biosensor chip detects genetic mutation with higher sensitivity

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to a smartphone, computer, or other electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance could lead to cheaper, faster and…

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Heard at the 14th ECDP in Helsinki

Digital pathology: Sometimes AI can outperform experts

Machine learning is adding a new dimension to pathology and already outperforming experts during some tasks, according to several speakers at the 14th European Congress on Digital Pathology (ECDP) who revealed up-to-date developments. However, whilst AI is set to herald a new future for digital pathology, Johan Lundin, associated professor for biomedical informatics and research director at the…

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Competition

Olympus Image of the Year – Celebrating art in science

Olympus’ Image of the Year Award for light microscopy in Europe recognizes the very best in life science imaging. Inspired by the beauty and breadth of images submitted for Image of the Year 2017, Olympus is now continuing its quest for the best light microscopy art in 2018. For the chance to win one of three prizes, applicants can submit life science light microscopy images to…

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Liquid chromatography-mass spectrometry

Increasing productivity and throughput in the lab

Liquid chromatography-mass spectrometry (LC-MS) has become a highly valued procedure in state-of-the-art laboratories – among them the Dr. Wisplinghoff Laboratory in Cologne, which adopted the method a decade ago. In its forty years, the organisation has provided physicians with the entire clinically relevant analysis spectrum of laboratory medicine, pathology, transfusion medicine as well as…

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Combined power

LC-MS research and routine use

LC/MS, i.e. the combination of liquid chromatography (LC) with mass spectrometry (MS) – an analytical method developed primarily for environmental analysis and live science – remains a keen topic in the medical laboratory. In recent European Hospital issues, we have outlined various reasons why this procedure is in increasingly popular in the medical lab. Here we continue with an interview…

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Sepsis treatment

Bedside testing can prevent antibiotic-induced hearing loss in new-borns

More than a million neonatal deaths worldwide each year are estimated to be due to sepsis. In the UK there are approximately 90,000 admissions to neonatal intensive care units per year. Nearly all these patients receive antibiotic therapy during their hospital stay, but babies with a specific genetic change can suffer irreversible hearing loss as a result. Now, in a collaboration between…

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When the phosphate decides...

Defense against viruses or autoimmune disorder?

The first defense line of the body against virus infections is composed of so-called restriction factors. SAMHD1, one of such restriction factors, does not only play a role in the defense against viruses but also in the development of autoimmune disorders and cancer. The question of which effect SAMHD1 exertsin the cell is decided by addition or removal of phosphate groups.

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Product of the Month

cellSens 2.1 – More Imaging for Less

Olympus cellSens 2.1 offers improved capabilities for flexible camera and microscope control and enables researchers to create sharp, noise-free images in less time. Helping to drive microscopy forward, cellSens 2.1 speeds up image analysis and features new image acquisition tools at a lower cost. In addition, existing cellSens users may be eligible for a free upgrade to cellSens 2.1. cellSens…

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High-throughput system

Speeding up flow cytometry to discover new drugs

A new SLAS Discovery original research article available now for free ahead-of-print, researchers from the Genomics Institute of the Novartis Research Foundation (GNF) highlights a diversity of approaches that their automated high-throughput flow cytometry has enabled for phenotypic drug discovery. Flow cytometry is a very powerful tool that has been used for decades and allows for…

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Status quo and recent developments

What's new in liquid chromatography-mass spectrometry?

European Hospital has recently focused on the development of liquid chromatography-mass spectrometry (LC-MS) for use in analytical/medical diagnostics. Dr Stavros Kromidas, an expert in high-performance liquid chromatography (HPLC) and author of several specialist books, has published his latest book ‘The HPLC-MS Handbook for Practitioners’. We interviewed him about this and a new technique…

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Pathology testing

The right tests – for the wrong reasons?

Figures show that the rates of pathology testing are continuing to rise despite a backdrop of financial constraint within the NHS. General practitioner (GP) Dr Jessica Watson has expressed concern that some tests are being carried out for the wrong reasons – often for a non-medical purpose – and that unnecessary tests are causing increased anxiety and uncertainty rather than offering…

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Medical technology

Genrui presents latest products

Genrui Biotech Inc., one of the leading Chinese developers and manufacturers of IVD equipment and reagents, present their latest POCT devices at the China International Medical Equipment Fair (CMEF). Among the presented devices are the 5-Part Auto Hematology Analyzer KT-6610, which uses advanced tri-angle laser scattering, flow cytometry technology to deliver white blood cell differential…

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Innovation

Siemens Healthineers debuts new thermocycler and AI-powered interpretation software

At the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2018), Fast Track Diagnostics, a Siemens Healthineers company, launches a new molecular thermocycler, the Fast Track cycler, and the complementary new FastFinder software. The Fast Track cycler is a compact platform that enables laboratories of all sizes to implement molecular testing with simplicity and speed…

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