Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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RT-PCR for COVID-19

First of 3 diagnostic tests for SARS-CoV-2 coronavirus available

Biotechnology company bioMérieux, a world leader in the field of in vitro diagnostics, is announcing the forthcoming launch of 3 different tests to address the COVID-19 epidemic and to meet the…

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Smart algorithm

Automated analysis of whole brain vasculature

Diseases of the brain are often associated with typical vascular changes. Now, scientists at LMU University Hospital Munich, Helmholtz Research Centre for Environmental Health and the Technical…

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Pandemic prevention

German lab developed coronavirus detection method

Investigators at Hannover Medical School (MHH) in Germany have developed a molecular assay for detecting the novel coronavirus SARS-CoV-2 (previously 2019-nCoV) on the automated Panther Fusion system…

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Understanding COVID-19

Why children are vital to slowing the coronavirus pandemic

Though the coronavirus disease COVID-19 so far appears to be largely sparing children, researchers are cautioning that it is critical to understand how the virus affects kids to model the pandemic accurately, limit the disease’s spread and ensure the youngest patients get the care they need. The warning comes from Steven L. Zeichner, MD, PhD, the head of UVA Health’s Division of Pediatric Infectious Diseases, and Andrea T. Cruz, MD, MPH, a pediatric emergency medicine physician at Houston’s Baylor College of Medicine. They have authored a commentary in the journal Pediatrics accompanying a new article that reveals a small percentage of infected children become seriously ill. Those at greatest risk include babies and preschoolers. “Many infectious diseases affect children…

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Improved grip and comfort

New cap design for capillary blood collection tubes

The MiniCollect Capillary Blood Collection System launched by Greiner Bio-One in 2016, has an improved cap on all its blood collection tubes. The new version, designed for easier opening, has an…

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Lab technician shortage

Addressing the critical lack of skilled lab workers

The UK and Europe are facing a serious lab skills shortage over the next decade with medical laboratories among the worst affected. An ageing population and skilled operators retiring without being…

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On the way to diagnostic mainstream

Liquid biopsy to advance cancer diagnosis

Liquid biopsy offers a new dimension to detection and stratification of cancer – yet the technique also faces hurdles and challenges in becoming a mainstream diagnostic approach that will help…

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Triple-negative forms impeded

Scientists stop breast cancer cells from spreading in the lab

Biologists have discovered a way to stop cells from one of the most aggressive types of breast cancer spreading in the lab. The study points towards new avenues of research to combat the devastating…

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Development of a highly sensitive analytical workflow

Collaboration for infectious disease diagnosis and patient monitoring

Thermo Fisher Scientific and NanoPin Technologies, Inc. have entered into a collaborative relationship to advance blood-based infectious disease detection technology through the development of highly…

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New virus 2019-nCoV

Scientists grow Wuhan coronavirus in the lab

Scientists from The Peter Doherty Institute for Infection and Immunity in Melbourne have successfully grown the Wuhan coronavirus (also known as SARS-CoV-2) from a patient sample, which will provide…

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Digitizing workflows

Dutch hospital expands imaging solution to include digital pathology

Medical imaging IT and cybersecurity company Sectra has signed a digital pathology contract with the Dutch hospital Zuyderland MC. A digital pathology workflow makes it possible to access and share…

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Update improves testing

Breast cancer guideline identifies most promising therapies

The updated guideline for estrogen and progesterone receptor (ER/PgR) testing in breast cancer, published jointly by the College of American Pathologists (CAP) and the American Society of Clinical…

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Outsmarting the immune system

'Super-human’ red blood cells for precise drug delivery

A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs throughout the body, which could specifically target infections…

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Dementia diagnostics

Lack of sleep might throw off Alzheimer’s test

A preliminary study has found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer’s disease, in their blood than when…

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Mass spec & proteomics

Tackling diabetes prevention from a different angle

A protein newly identified as important in type 1 diabetes can delay onset of the disease in diabetic mice, providing a new target for prevention and treatment in people, according to research led by…

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Deep learning vs. AML

AI-driven blood cell classification supports leukemia diagnosis

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood…

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Direct-from-blood diagnostic

T2Resistance Panel receives CE mark

T2 Biosystems, Inc., a leader in the development and commercialization of medical diagnostic products, and CARB-X, a global non-profit partnership dedicated to accelerating R&D innovation to…

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Sprue POCT

Celiac disease: faster detection through new method

Researchers from the University of Helsinki developed a novel diagnostic method for the rapid on-site measurement of antibodies from patient samples. Now they have applied this new method for the…

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In England

165 new antibiotic resistant infections every day

PHE’s latest English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) report shows that there were an estimated 61,000 antibiotic resistant infections in England during…

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Microbiological big data analysis

Building a 'Microbiome Search Engine'

Big data makes big promises when it comes to providing insights into human behavior and health. The problem is how to harness the information it provides in an efficient manner. An international team…

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Coronavirus disease diagnostics

Emergency Use Authorization for COVID-19 test

French in vitro diagnostics company bioMérieux announced that its subsidiary, BioFire Defense, has received Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration of its BioFire…

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COVID-19 status

Whole genome sequencing to map coronavirus spread

The Government and the UK’s Chief Scientific Adviser have backed the UK’s leading clinicians and scientists to map how COVID-19 spreads and behaves by using whole genome sequencing. Through a…

Products from Labbook

Sarstedt – Low Retention Pipette Tips

PIPETTE TIPS

Sarstedt – Low Retention Pipette Tips

SARSTEDT AG & CO. KG
Medat – Laboratory Information System

LIS, Middleware, POCT

Medat – Laboratory Information System

Medat Computer-Systeme GmbH
Eppendorf – Mastercycler nexus X2

Research Use Only (RUO)

Eppendorf – Mastercycler nexus X2

Eppendorf AG
Shimadzu – Axima iDplus Performance

Mass Spectrometry

Shimadzu – Axima iDplus Performance

Shimadzu Europa GmbH
Greiner – Saliva Collection System

Rapid Testing

Greiner – Saliva Collection System

Greiner Bio-One
Horiba Medical – Yumizen G1550

Hemostaseology

Horiba Medical – Yumizen G1550

HORIBA Medical
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Coronavirus in laboratory medicine

Video: COVID-19 at a glance

To provide reliable information about the coronavirus disease COVID-19, Professor Giuseppe Lippi, Director of the Laboratory for Clinical Chemistry and Hematology at the University Hospital of Verona, Italy, gives an overview on the current state of scientific knowledge on COVID-19 and the SARS-CoV-2 virus. The video was provided by the American Association for Clinical Chemistry (AACC), who…

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Endoscope drying

Empowering Reprocessing Staff: Improving Patient Safety

Human factor aspects of reprocessing can never be completely avoided yet staff can be empowered to reduce the risk of infection. This was an important conclusion established at a multidisciplinary expert panel held at Pentax Medical’s R&D Center, discussing infection risk mitigation in endoscopy. This panel of experts, consisting of physicians, nurses, microbiologists, infection control…

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Blood test & AI power

Early brain tumour detection – within minutes

A simple blood test coupled with artificial intelligence (AI) analysis could help spot the signs of a brain tumour sooner in patients. Brain tumour diagnosis is difficult: patients often see their family doctor (GP) several times before referral for a scan. However, research presented at the 2019 National Cancer Research Institute (NCRI) Cancer Conference in Glasgow last November suggests the…

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Lab equipment

New high-precision digital reagent dispensers launched at SLAS 2020

Scientists working across drug metabolism and pharmacokinetics, bioanalytical, pre-clinical and clinical trial applications can now access a range of digital reagent dispensers designed to enable assay miniaturization, boost productivity and improve accuracy of results. Offering enhanced dispensing precision, the new systems use ten times less reagent compared to manual pipetting workflows,…

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TMAs in digital pathology

Infusing tissue micro­arrays with new, 'digital' life

The advent of digital pathology is helping to address some of the challenges surrounding tissue microarrays as they are integrated into the digital workflow, in some ways giving them ‘a new lease of life’, according to Professor Inti Zlobec, who spoke at the Digital Pathology and AI Congress in London last December. As Head of the Translational Research Unit at the Institute of Pathology,…

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Laboratory equipment

More safety for blood banks

Ensuring the quality of blood donations is vital. Data collected during the various processes involved must be fully traceable and documented, the company Andreas Hettich GmbH emphasises. Based in Tuttlingen, Germany, the company has produced laboratory equipment for 115 years, today focusing on centrifuges and incubators and employing 420 people worldwide. Its new HettInfo II documents all steps…

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Laboratory worktable

See the GrossPath GP-1500 live in action!

Laboratory staff is permanently exposed to harmful formalin vapors. The GrossPath GP-1500 reduces this risk to a bare minimum as contaminated air is being extracted immediately downward and also backwards. Additionally, the tissue grossing station complies with MAC (maximum allowable concentration) values for formalin.

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Innovative design

Maximum power for efficient processes

Vacuum systems are the best solution for the safe disposal of biological liquids in laboratories. A coated membrane, special valves and a high gas tightness offer the safe and sustainable disposal of biological liquid waste. The latest generation of Axonlab's universal mini vacuum extraction system was developed in a development period of around 18 months. The patented product combines years of…

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Minimising infection risk

Drying in endoscope reprocessing: Essential to patient safety

In practice, the drying of the endoscope is often underestimated and therefore a possible pitfall for hygiene and reprocessing steps. As the importance of endoscopic retrograde cholangio-pancreatography (ERCP) procedures and their impact on patients’ lives remains unwavering, the medical community is continuously looking for ways to improve this field of expertise. What better way to learn more…

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Presented at the NCRI cancer conference

Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells, according to new research presented at the 2019 NCRI Cancer Conference. Cancer cells produce proteins called antigens that trigger the body to make antibodies against them – autoantibodies. Researchers…

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Product of the Month

Using safety products reduces the risk of needlestick injuries

If a health sector employee falls ill with a bloodborne illness, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with an NSI, is one of the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Don’t take the dangers posed by NSI lightly: get…

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MRSA & Co.

Test to detect antibiotic resistance in less than 45 minutes

Scientists from Scotland are developing a low cost, rapid diagnostic sensor test which aims to show the susceptibility of bacteria to antibiotics within 45 minutes. Laboratory testing of samples can take up to two days and the new test aims to allow doctors to be able to prescribe the correct antibiotic to a patient for an infection more quickly. In a research paper published in the journal…

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Lab medicine

Four perspectives on preanalytics and patient safety

BD participated in the 5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) conference on preanalytical phase in Zagreb, Croatia 22–23 March 2019. At the conference, we met Mr Steve McManus, Prof Ana-Maria Simundic, EFLM conference chair, Prof Mario Plebani and Dr Alexander von Meyer, member of the EFLM conference scientific committee. Prof Simundic and Dr von Meyer…

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Laboratory economics

Lab services: Don’t cut the cost!

In recent years, whenever the German media reported on laboratory medicine, questions consistently arose: ‘How can excessive costs for lab services be cut?’ and ‘How could money saved be distributed among other medical specialists and general medicine practitioners (GPs)?’ The questions are myopic in their failure to address two important aspects of laboratory medicine – its…

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Cognitive chemical manufacturing

‘Lab-bot’ could revolutionise hunt for cancer drugs

A robot-controlled laboratory where decisions are made by artificial intelligence will change the way new drugs are discovered, says a leading researcher. The engineer leading a project to develop a prototype "lab-bot" says it will reduce the time it takes to identify and synthesise molecules for new medicines – a process that can take years as scientists refine the shape and property…

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Combatting nosocomial infections

A&E Staphylococci POCT

Martin Möckel and Dorothee Riedlinger, from the Charité Medical University Berlin, Emergency and Acute Medicine Campus Virchow-Klinikum, and Campus Charité-Mitte report on POCT testing in the A&E Department to screen for Staphylococcus aureus colonisation of the nose or throat. People colonised with Staphylococci are at increased risk of developing a nosocomial, i.e. hospital acquired…

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Disinfection

Why rigorous hygiene practices are vital

Nosocomial infections present enormous challenges for medical facilities, involving huge hygiene efforts from staff, on patients as well as medical and non-medical products. At MedtecLIVE 2019, in Nuremberg, Susanne Harpel (Dipl. Ing), Deputy Head of the Institute for Hygiene and Environmental Medicine at Giessen/Marburg Univer­sity Hospital, presented desirable contamination efforts during the…

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Workforce challenges

Pathologists will hold a pivotal role

Amid ever-growing demand for services, significant challenges face the pathology workforce in the years ahead but – there are also good opportunities. With advances in technology and the advent of artificial intelligence as a decision-making support tool, Professor Jo Martin, President Royal College of Pathologists (RCPath) in the UK, believes there remain opportunities for pathology to play a…

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Instruction for Use

Infection risk mitigation by simplified IFUs

Duodenoscopes have been long recognized to require precise execution of reprocessing instructions to properly clean and disinfect. According to Beilenhoff, et al. (2018), it is crucial to follow the manufacturer’s Instructions for Use (“IFU”) at all times to make sure the duodenoscopes are properly cleaned. Yet, IFUs are not always easy to follow.

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A STAMP with high value

New tech makes biopsies less invasive, more informative

A team of researchers has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive biopsies. With this new technology called STAMP (Sequence-Topology Assembly for Multiplexed Profiling), comprehensive disease information can be obtained faster, at a much earlier stage of the…

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t-MALDI-2

Dual-beam laser mass spectrometry gives unique insights

Cells are the basic building blocks of life – and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century. The development of mass spectrometry (MS) methods – those which define the chemical composition of cells – represented a further milestone for research in the field of cell biology. In the latest issue of the journal Nature…

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