From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.
Since the firm was created almost 30 years ago, Roland Steger, the founder and CEO of Axon Lab AG, always regarded it as important for it to help resolve social challenges as well as achieving commercial success: “It was always clear to me that a purely economic, profit-focused business strategy is not sufficient in the long term. A spirit of partnership and cooperation, supporting projects…
The critical element of testing for sepsis lies not so much in the location but in the timing and rapidity of results, according to Professor Jeannine T. Holden from Beckman Coulter Early identification enables treatment protocols to be delivered more quickly, offering better patient outcomes. Those most at risk, suggests Holden, are not patients within the intensive care unit – who are already…
The team of the Heinz Nixdorf Chair of Biomedical Electronics at the Technical University of Munich focuses on innovative diagnostic tools to accelerate the development towards personalized medicine. Therapies tailored to the individual patient – this is the future not only of oncology but of many medical disciplines. “At this point, however,” concedes Professor Dr Oliver Hayden,…
From May 19-23, Sysmex will be demonstrating its latest comprehensive solutions in diagnostic equipment at the 23rd EuroMedLab in Barcelona. Come and visit us at booth 30!
DRG's fully-automated analyzer with unique technology allows the automated determination of niche parameters like Calprotectin, Free Testosterone, Salivary Cortisol, Renin, Aldosterone, Hepcidin and brand new celiac disease tests: anti-tTG and -DGP.
As mass spectrometry proves to be a more consistent and accurate tool in biochemical measures, with acknowledged advantages over immunoassays, its role in diagnostics has escalated. Headed by Professor Ruth Andrew, the pioneering Mass Spectrometry Core Facility at the University of Edinburgh, aims to offer researchers access to expert scientists and specialist resources to support clinical…
Liquid chromatography/mass spectrometry (LC-MS) is an established powerful tool in routine clinical use and clinical research. However, to further capitalise on its benefits, instrument and consumables vendors should continue to improve accessibility and ease-of-use, according to Dr Debadeep Bhattacharyya, senior marketing manager for clinical and forensic at Thermo Fisher Scientific. Remarkable…
Induced pluripotent stem (iPS) cells are among the most important tools in modern biomedical research, leading to new and promising possibilities in precision medicine. To create them requires transforming a cell of one type, such as skin, into something of a blank slate, so it has the potential to become virtually any other kind of cell in the body, useful for regenerative therapies for…
Beckman Coulter is launching the ClearLLab 10C System for the clinical flow cytometry lab. The new system is the first 10-color IVD panel of immunophenotyping reagents cleared by the Food and Drug Administration (FDA) for both lymphoid and myeloid lineages. The four dry pre-mixed antibody tubes use the company’s DURA Innovations technology, eliminating the need to pipette antibodies, improving…
Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients’ blood and urine. These “liquid biopsies” are less invasive than a traditional biopsy, and can provide information about what’s happening throughout the body instead of just at a single site. Now researchers at the University of Michigan Rogel Cancer…
Beckman Coulter announced that the latest addition to its market-leading automation portfolio, the DxA 5000 total laboratory automation (TLA) solution has achieved European CE Mark and China Food and Drug Administration approval. In today’s healthcare environment, laboratories are highly focused on enhancing patient care by driving faster turnaround time, delivering quality results and…
Cognitive impairment associated with cancer, also known as “chemobrain”, has gained recognition as a complication of the disease and its treatment, as it can negatively affect the daily lives of cancer patients and survivors. Chemobrain can be subtle yet persistent, with some cancer patients reporting difficulties related to memory and attention even months after completing their treatment.…
Digital pathology can gain huge benefits from rapid image search and the effective extraction of knowledge from large medical archives via artificial intelligence (AI). It facilitates identification of anatomical and pathological similarities, significantly enhances the clinical workflow, and ultimately paves the way for more informed diagnosis and better patient outcome. Effective archive…
Digital pathology, combined with the power of Artificial Intelligence (AI), is one of the most promising fields for the delivery of precision medicine. In the first keynote address for the 5th Digital Pathology & AI Congress (Europe) held in London last December, Professor of Pathology, Marilyn Bui, focused on how digital pathology is impacting on precision medicine. During her address,…
Interpretation of complex profiles of laboratory results can be significantly improved via multivariate pattern recognition software. A multivariate pattern recognition software, developed by a team led by Dr Piero Rinaldo at Mayo Clinic in Rochester, USA, aims to integrate results to diagnose a particular condition in a single score, in an objective evidence-based way that is open to worldwide…
As a synthetic opioid approved for treating severe pain, fentanyl has shown clear medical benefits. However, in recent years, continuous abuse of fentanyl and its derived analogues substances has become a major public health issue – overdoses and deaths associated with illicitly-manufactured fentanyl rose dramatically. Some of these synthetic analogues have extremely high potency and only…
In the past, we repeatedly focused our attention on developments in the clinical application of mass spectrometry-based methods in patient care. Various aspects became significant. Today, the use of Liquid Chromatography Triple Quad Mass Spectrometry (LC-MS/MS) for therapeutic drug monitoring (TDM) can be considered today’s standard, although classically applied immunoassays continue to be…
Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analysing the genetic faults in a sample of their blood. The researchers, funded by Cancer Research UK, The Christie Charity, AstraZeneca and the NIHR Manchester Biomedical Research Centre (BRC), demonstrated in their feasibility study that a blood test can be carried out…
A major milestone on its strategic mission to lead in sepsis diagnostics, Beckman Coulter announced that its Early Sepsis Indicator has received 510(k) clearance from the U.S. Food and Drug Administration (FDA). Sepsis is a global healthcare crisis that affects more than 30 million people worldwide. The Early Sepsis Indicator is a first-of-its-kind, hematology-based cellular biomarker that is…
Research has revealed that a new blood test is able to detect disease relapse up to two years earlier than imaging in patients with early-stage breast cancer. The research, carried out by the University of Leicester and Imperial College London and funded by Cancer Research UK, showed that the blood test was able to detect 89 per cent of all relapses, on average 8.9 months quicker than imaging.
Gene sequencing has been progressing in leaps and bounds over the past few years. The process of determining the order of nucleotides in DNA has become faster and more precise. Moreover, today both microbial DNA and host DNA can be identified in the blood sample of an infected patient, isolated and sequenced. “We are facing a technological revolution, but we still struggle with actually…
ColorAX2 with its new staining technology offers you low staining reagents consumption. The compact, lightweight and autonomous system features 10 independent staining chambers and allows easy and clean procedures. The unique technology of ColorAX2 prevents cross-contamination and significantly reduces the consumption of reagents and waste. Besides it helps you reduce your operation costs. The…
Insufficient knowledge of infection control, resulting in insufficient compliance, increases the risk of hospital acquired infections (HAIs) and multiresistant pathogens that put patients at risk. At the 2019 Annual General Meeting of the German Society for Hygiene and Microbiology e.V. (DGHM) in Göttingen, Professor Frauke Mattner, Senior Consultant at the Institute of Hygiene, Kliniken der…
Antimicrobial resistance is a global issue, with 700,000 deaths per year and 10 million expected deaths by 2050, according to predictions. Appropriate antimicrobial therapy can help to save lives, and a long awaited cure for carbapenemase-producing enterobacteriaceae (CPE) will soon be released, according to eminent Spanish expert Jose Mensa Pueyo, speaking at a Madrid meeting in March. The past…
Early detection and confirmation of carbapenemase-producing enterobacteriaceae (CPE) are essential when choosing the appropriate antimicrobial therapy and to implement infection control measures. Here, a leading Spanish microbiologist reviews an arsenal of tools currently available to clinicians. Resistance to beta-lactam antibiotics in enterobacteriaceae (EBc) is due to one or more of these…
