Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

News • Machine learning analysis

Breast cancer: AI predicts metastasis from recurrence

The location and timing of breast cancer recurrence may allow AI to predict the risk of metastasis, a new study shows. This is an essential step towards developing personalised treatment strategies.

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In today’s fast-paced healthcare landscape, efficiency and accuracy are essential in overcoming workload challenges. Pathology laboratories are under pressure to keep up with growing demands, all while ensuring standardised, consistent and high-quality results. 

News • HBV point-of-care identification

Hepatitis B: rapid diagnostic test to halt mother-to-child transmission

A new rapid diagnostic test can identify pregnant women at elevated risk of transmitting hepatitis B to their babies. This could help prevent mother-to-child transmission during childbirth.

Article • Point-of-care diagnostics

Improving women’s health in remote regions with digital pathology

Point-of-care diagnostics based on a combination of mobile-sized scanners and artificial intelligence (AI) are helping save the lives of women in low-resource settings. The AI technique is being…

News • Electrochemical biosensing

Nanotube sensors enhance accuracy in continuous health monitoring

Researchers have succeeded in producing sensors from single-wall carbon nanotubes that are suitable for detecting even minute changes in specific substances in the body, such as female hormones.

Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative progression.

Article • Digital pathology discussion panel

The AI tools pathologists want and need

The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at…

News • Intrinsic electrical activity drives cancer progression

SCLC: Deciphering the unusual aggressiveness of small cell lung cancer

New research reveals that self-generated electrical activity of small cell lung cancer (SCLC) directly promotes tumor metastasis and progression. This may provide new avenues for future treatments.

News • Circulating tumor DNA analysis

Liquid biopsy helps reduce chemotherapy in colon cancer patients

For patients, a liquid biopsy which checks for circulating tumour DNA of colon cancer, resembles a standard blood test. However, the method helps avoid chemotherapy for many, a new study finds.

Products from Labbook

Sample Processing

Sarstedt · Decapper DC 1200 / Recapper RC 1200

SARSTEDT AG & CO. KG

Blood Gases, Electrolytes, Oximetry

KABE Labortechnik – Pipette-Adapter for Capillaries (PAC)

KABE LABORTECHNIK GmbH

Clinical Chemistry

Fujifilm Wako · Hyaluronic Acid LT Assay

FUJIFILM Wako Chemicals Europe GmbH

Clincal Chemistry

Sarstedt · S-Monovette® cfDNA Exact

SARSTEDT AG & CO. KG

Clinical Chemistry

Sarstedt · S-Monovette Lithium Heparin Gel+

SARSTEDT AG & CO. KG

LIS / Middleware / POCT

CliniSys · Order & Results Management

Clinisys Deutschland GmbH

Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

News • Deep and ensemble learning improve performance

New AI tool surpasses previous methods in colorectal cancer tissue analysis

Researchers developed an advanced AI tool for automatic analysis of colorectal cancer tissue slides. The new model outperformed all predecessors in the classification of tissue microscopy samples.

News • Aldosterone-producing adenomas

The surprising complexity of adrenal gland tumors

New research uncovers the hidden diversity of adrenal gland tumors, shedding light on how they cause unusual medical symptoms and paving the way for new drug treatments.

News • Reseach on neurofilament light chain proteins

ALS: Improving diagnosis and management with new blood test

A new blood test, using neurofilament light chainproteins as biomarker, could lead to better diagnosis and management of amyotrophic lateral sclerosis (ALS).

News • Cell-free tumor DNA analysis

Liquid biopsy to unlock breast cancer treatments

New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.

News • Detection of hereditary syndrome

IVDR certification for breast and ovarian cancer assays

MRC Holland recently announced that five SALSA MLPA assays for the detection of hereditary breast and ovarian cancer (HBOC) syndrome were recently CE-marked for in vitro diagnostic (IVD) use under the new In-Vitro Diagnostic Regulation EU 2017/746 (IVDR).

News • Alternative to diagnostic brain imaging

Exploring the potential of blood tests for dementia diagnosis

Molecular changes associated with brain inflammation and dementia can be detected in the blood. Researchers want to use this to establish blood tests as an alternative to more costly brain scans.

News • Multi-omics-based prediction

Pancreatic cancer: 'biomarker panel' brings hope for early detection

The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.

News • Age-related cellular and molecular changes

How aging breast tissue shapes breast cancer risk

Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.

News • Study explores impact

How brain trauma can trigger Alzheimer's disease

Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.

News • Potentiator of AMR emergence and expansion

Diabetes as a driver of antibiotic resistance

Microbiologists have just shown that people with diabetes are more likely to develop antibiotic-resistant strains of Staphylococcus aureus, a leading cause of AMR-associated infections and deaths.

News • Alteration of immune response

Multiple myeloma: dangerous diversity

When multiple myeloma cancer cells break out and multiply outside the bone marrow, a wide variety of tumor cells arise, accompanied by a significantly altered immune response, new research shows.

News • Research on RAD51 biomarker

Next-generation sequencing for personalizing prostate cancer treatment

Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.

News • Detection of glial fibrillary acidic protein (GFAP)

Blood test may detect stroke type before hospital arrival

A new blood test that detects a specific brain protein may help doctors determine the type of a stroke faster and allow them to start safe treatment for people before they get to the hospital.

News • Concerning discovery

New antibiotics can develop resistance before even hitting the market

Two recent studies find that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.

News • Recent detections cause concern

Polio return to Europe: call for urgent action

Europe has been polio-free since 2002 – but a recent surge in poliovirus detections across several European countries shows that the threat from this vastly-forgotten disease is over, warn experts.

News • Successful clinical validation

Urine-based test detects aggressive prostate cancer

Researchers have clinically validated a previously developed urine test for prostate cancer screening, which can potentially bypass invasive procedures among men who are unlikely to benefit.

News • Reactive glial responses

Mapping the brain's self-healing ability after stroke

Helping the brain repair itself after a stroke: A new study based on unique tissue samples from Denmark's Brain Bank may pave the way for new treatments that support brain regeneration.

News • Molecular mechanism discovered

Researchers find a way to stop harmful cells after cancer treatment

Senescent cells, which may appear after chemotherapy or radiotherapy, can jeopardize patients' recovery. A study describes a new mechanism to eliminate these cells in cancer patients.

News • Paediatric research

Molecular ‘fingerprint’ of long Covid in children's blood discovered

A new study has shown that the molecular signature of long Covid can be found in blood samples of children. Using an AI tool, the researchers were capable of diagnosing the condition with 93% accuracy.

News • Post-acute sequelae

Long Covid: Study tracks physical and cognitive impairments

Self-reported, persisting health problems after Sars-CoV-2 infection are commonly described. However, the long-term prognosis of post-Covid-19 syndrome is unknown. A new study aims to change this.

News • Laboratory equipment and technology fair

Labs Expo gets ready for third edition

This March, the city of Poznań in Poland will host experts from the laboratory industry for the third edition of the Labs Expo Laboratory Equipment and Technology Fair.

News • Patient-derived samples

New ‘explant’ technique predicts breast cancer therapy response

A new study measured how well breast cancer patients’ tumour ‘explants’ respond to chemotherapy or HER2 antibody therapy in the laboratory. This could help improve clinical outcomes.

News • Promising prototype

A “diagnostic wand” to detect oral cancer

Liverpool physicists have developed a “diagnostic infrared wand” to more accurately predict the prognosis of oral cancer lesions than current H&E staining techniques.

News • Osteosarcoma research

Driver behind aggressive bone cancer identified

By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.

1776 show more articles

Laboratory/pathology

News • Machine learning analysis

Sponsored • Laboratory automation

News • HBV point-of-care identification

Article • Point-of-care diagnostics

News • Electrochemical biosensing

Article • Detection of neurodegenerative condition

Article • Digital pathology discussion panel

News • Intrinsic electrical activity drives cancer progression

News • Circulating tumor DNA analysis

Products from Labbook

Sample Processing

Blood Gases, Electrolytes, Oximetry

Clinical Chemistry

Clincal Chemistry

Clinical Chemistry

LIS / Middleware / POCT

Article • Promising, but in need of further validation

News • Deep and ensemble learning improve performance

News • Aldosterone-producing adenomas

News • Reseach on neurofilament light chain proteins

News • Cell-free tumor DNA analysis

News • Detection of hereditary syndrome

News • Alternative to diagnostic brain imaging

News • Multi-omics-based prediction

News • Age-related cellular and molecular changes

News • Study explores impact

News • Potentiator of AMR emergence and expansion

News • Alteration of immune response

News • Research on RAD51 biomarker

News • Detection of glial fibrillary acidic protein (GFAP)

News • Concerning discovery

News • Recent detections cause concern

News • Successful clinical validation

News • Reactive glial responses

News • Molecular mechanism discovered

News • Paediatric research

News • Post-acute sequelae

News • Laboratory equipment and technology fair

News • Patient-derived samples

News • Promising prototype

News • Osteosarcoma research