Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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Presented at the NCRI cancer conference

Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells,…

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MRSA & Co.

Test to detect antibiotic resistance in less than 45 minutes

Scientists from Scotland are developing a low cost, rapid diagnostic sensor test which aims to show the susceptibility of bacteria to antibiotics within 45 minutes. Laboratory testing of samples can…

Product of the Month

Using safety products reduces the risk of needlestick injuries

If a health sector employee falls ill with a bloodborne illness, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with an NSI, is one of…

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In England

165 new antibiotic resistant infections every day

PHE’s latest English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) report shows that there were an estimated 61,000 antibiotic resistant infections in England during 2018, a 9 percent rise from 2017.[i]

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Lab medicine

Four perspectives on preanalytics and patient safety

BD participated in the 5th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) conference on preanalytical phase in Zagreb, Croatia 22–23 March 2019. At the conference, we met…

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Laboratory economics

Lab services: Don’t cut the cost!

In recent years, whenever the German media reported on laboratory medicine, questions consistently arose: ‘How can excessive costs for lab services be cut?’ and ‘How could money saved be…

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Cognitive chemical manufacturing

‘Lab-bot’ could revolutionise hunt for cancer drugs

A robot-controlled laboratory where decisions are made by artificial intelligence will change the way new drugs are discovered, says a leading researcher. The engineer leading a project to develop a…

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Advanced chemistry

Enhancing sensors that could help cure Alzheimer's and Diabetes

Viscosity sensors are used by scientists fighting various diseases, such as Alzheimer's and Diabetes. Vilnius-based chemist Aurimas Vyšniauskas has enhanced their measuring capabilities. This…

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T2Resistance Panel

Rapid diagnosis of bacterial infections

T2 Biosystems and CARB-X announced that the T2Resistance Panel is the first diagnostic to graduate from CARB-X’s portfolio.

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Combatting nosocomial infections

A&E Staphylococci POCT

Martin Möckel and Dorothee Riedlinger, from the Charité Medical University Berlin, Emergency and Acute Medicine Campus Virchow-Klinikum, and Campus Charité-Mitte report on POCT testing in the…

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Disinfection

Why rigorous hygiene practices are vital

Nosocomial infections present enormous challenges for medical facilities, involving huge hygiene efforts from staff, on patients as well as medical and non-medical products. At MedtecLIVE 2019, in…

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Workforce challenges

Pathologists will hold a pivotal role

Amid ever-growing demand for services, significant challenges face the pathology workforce in the years ahead but – there are also good opportunities. With advances in technology and the advent of…

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Pushing for integration with radiology

Digital pathology & AI: Multiple viewing improves consultation

Pathology is embracing digitisation just as radiology did over 20 years ago and both specialties are looking at new ways to integrate each other in their workflows. AI could fuel this sparkling…

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MedTech

Turbo-charging pharmaceutical biotechnology simulations

New simulation technology developed by TU Graz is designed to make the production of biopharmaceuticals more efficient, cost-effective and comprehensible for manufacturers.

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Instruction for Use

Infection risk mitigation by simplified IFUs

Duodenoscopes have been long recognized to require precise execution of reprocessing instructions to properly clean and disinfect. According to Beilenhoff, et al. (2018), it is crucial to follow the…

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A STAMP with high value

New tech makes biopsies less invasive, more informative

A team of researchers has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive…

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t-MALDI-2

Dual-beam laser mass spectrometry gives unique insights

Cells are the basic building blocks of life – and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century. The development of mass…

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Feasibility study

Liquid biopsy to complement early breast cancer screening

Investigators from the Biomedical Research Institute of Malaga [(IBIMA)-CIMES-UMA, Malaga Spain] and collaborators have published the first pilot study to examine the use of a non-invasive liquid…

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Methods, quality assurance, commercial providers issues

Molecular testing takes a huge leap

In terms of success in revolutionary cancer treatment, molecular genetic examination procedures have developed immensely over recent years. They now range from conventional polymerase chain reactions…

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Deep learning vs. AML

AI-driven blood cell classification supports leukemia diagnosis

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood…

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Immunoassay

The quantitative measurement of cardiac troponin I concentration

Pathfast hs-cTnI is a chemi-luminescent enzyme immunoassay (CLEIA) for the quantitative measurement of cardiac troponin I (cTnI) concentration in whole blood or plasma at the point-of-care (POC).…

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Mortality risk

A new biomarker to predict your lifespan?

Fourteen metabolic biomarkers can predict long term mortality in individuals helping to determine life expectancy in general populations, a new study in the journal Nature Communications reports. In…

Products from Labbook

Sarstedt – Low DNA Binding Micro Tubes

Research Use Only (RUO)

Sarstedt – Low DNA Binding Micro Tubes

SARSTEDT AG & CO. KG
Sysmex – XN-9100 Sorting & Archiving

Integrated Hematology

Sysmex – XN-9100 Sorting & Archiving

Sysmex Europe GmbH
Lifotronic - FA-160 Immunofluorescence Analyzer

Other

Lifotronic - FA-160 Immunofluorescence Analyzer

Lifotronic Technology Co., Ltd
FUJIFILM Wako - Autokit CH50 Assay

Clinical Chemistry

FUJIFILM Wako - Autokit CH50 Assay

Wako Chemicals GmbH
Fujirebio – Lumipulse G600II

Immunochemistry

Fujirebio – Lumipulse G600II

Fujirebio Europe NV
AB Medical – V-Tube Clot Activator with Gel

Clinical Chemistry

AB Medical – V-Tube Clot Activator with Gel

AB Medical V-Tube
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Laboratory workflow

Sophisticated tech transforms Spanish lab

Touring the laboratory at the Clínic de Barcelona Hospital, Dr José Luis Bedini revealed how the latest Siemens Healthineers technology has transformed workflow to deliver quicker results, improve efficiency, conserve energy, and thus make the team of technicians very happy! In recent months the Core Lab Operative Area at Hospital Clínic de Barcelona has undergone a transformation due to the…

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Personalized medicine

Exploring the potential of High-Content Screening

The key challenges and opportunities surrounding High-Content Screening have been outlined in a presentation to leading scientists and technologists at a major lab conference. Speaking at the recent SLASEurope 2019 event in Barcelona, Professor Matthias Nees from the Institute of Biomedicine in the Department of Biology at the University of Turku, Finland, outlined the potential of High-Content…

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Surface-enhanced Raman spectroscopy

The lab-on-a-chip SERS platform

Analytically sensitive and specific detection of pharmaceuticals or metabolites in bodily fluids, as well as fast and reliable detection of human pathogens, are major challenges for instrument-based analytics in medical diagnostics. Over the past few years the combination of surface-enhanced Raman spectroscopy (SERS) and microfluidic devices (Lab-on-a-Chip) has emerged as a perfectly suited…

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Seeking the right questions

Developing algorithms to assist routine pathology

Artificial Intelligence (AI) is destined for a significant role in assessing histology data but the key to developing the necessary algorithms lies in data quality – rather than the quantity, according to Professor Jens Rittscher. He also warns that we are some distance from seeing AI replacing human pathologists in this scenario, primarily because presently the risks of automated…

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Safety products

Abolish needlestick injuries

If a health sector employee falls ill with a bloodborne disease, the cause is often a previous injury from a sharp, contaminated object. Direct blood-to-blood contact, such as with a needlestick injury (NSI), is among the recurring causes of infection. It isn’t possible to vaccinate against HIV, for instance, and the consequences of an infection remain fatal. Among the most effective ways to…

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IT Solutions

Siemens Healthineers shows the power of data in the lab at AACC 2019

At the 71st AACC Annual Scientific Meeting & Clinical Lab Expo, Siemens Healthineers features in Booth #1039 its innovative IT solutions to combat the laboratory’s staffing challenges, limited budgets, and the increasing complexity in sample management and testing. “We will be demonstrating the power of our broad IT offerings and how the data they deliver, and artificial intelligence, can…

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Dry Unitized Reagent Assays

Beckman Coulter presents online cost benefit tool at AACC 2019

Beckman Coulter Life Sciences launched the online DURA Innovations calculator tool, a powerful cost benefit analysis resource to accompany its latest Cost Benefit Calculator Handbook. The free online tool enables laboratories to quantify the value of converting to a standardized flow cytometry workflow using the company’s dry reagent technology. The new calculator enables customers using liquid…

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Innovations for the clinic

Thermo Fisher Scientific showcases clinical lab equipment at AACC 2019

Thermo Fisher Scientific Inc. is showcasing its latest instruments, assays and software for improving speed, accuracy and usability across clinical and research labs during the 71st American Association for Clinical Chemistry Annual Scientific Meeting and Clinical Laboratory Exposition (AACC 2019). Thermo Fisher is exhibiting in booth 2110 at the Anaheim Convention Center, Anaheim, Calif., August…

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Acoustic Mist Ionization Mass Spectrometry

A future role for AMI-MS

Acoustic Mist Ionization Mass Spectrometry (AMI-MS) has played a pivotal role in the evolution of high-throughput screening (HTS) and now steps are being taken to advance this field to other potential applications. AstraZeneca has been an important player in this area, having already run more than 10 full collection HTS campaigns against a range of enzyme target types, and the company is now…

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Fixed DNA Molecule Array

World’s fastest DNA testing method created

A group of scientists from Vilnius University have developed the world’s fastest DNA testing method, reducing DNA testing costs by 90%. It identifies changes in chromosomes, genes, or proteins to determine a genetic condition or eliminate the chance of the formation or passing on of a gene-based disorder amongst humans and animals. At present, the sole method of genetic testing is the DNA…

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Lab IT

Old software makes old mistakes …

Since the microprocessor entered the medical laboratory we have watched how those responsible also have been confronted with the errors in the software supplied with it. Obviously, such errors are to be avoided or found and corrected before use. Nonetheless complete error-free software remains a dream. ISO 15189:2012 makes it obligatory for the manufacturer to identify errors in the form of…

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Human-Computer Interaction

Shaping the laboratories of the future

The need to effectively address HCI – Human-Computer Interaction – is emerging as the key challenge in creating a productive and efficient laboratory of the future. The subject was examined in detail by Andreas Schuller from the Fraunhofer Institute for Industrial Engineering in Stuttgart, Germany, during the recent SLASEurope2019 conference in Barcelona, which brought together more than…

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WLAN-capability

Turning microscopes in the classroom into a wireless imaging system

Today’s educational landscape is changing rapidly thanks to technological advances. Introducing wireless capabilities to science classrooms enables lecturers to teach and students to learn in an engaging digital environment that promotes teamwork. Equipped with a WLAN-capable Olympus EP50 camera, every microscope in a classroom becomes a wireless imaging system. Using its own WLAN signal*, the…

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Collaboration

Partnership to enhance pharma drug development and single cell research

Olympus and Cytosurge AG, developer of the disruptive and patented FluidFM technology, announced their collaboration to significantly expand the awareness and availability of the FluidFM BOT* – a cutting-edge system for single cell manipulation and live cell imaging – in Europe, the Middle East and Africa (EMEA). By pooling together each other’s world-class competences and by listening to…

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Process optimisation

The Lean concept in digital pathology

We talked to Dr Annika Blank, Consultant and Lean green belt, about eight-year experience with the concept and optimisation of processes, the implementation of digital pathology and a voice recognition system for patient management. "The biggest and most cost intensive step taken to optimise workflows was the refurbishment of our laboratory, which was completed in 2016. This allowed us to…

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Rapid, reliable microbe identification

The Bologna Workflow System

Many countries across the world are challenged with a rising number of incidences of multi-drug resistant (MDR) organisms infecting the population, and for several years, a clear pattern of increased resistance has emerged in southern and eastern European countries. For example, in countries such as Italy, a reduced number of therapeutic options remain available for highly pathogenic infections,…

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Strategic partnership

Unlocking the full potential of EarlyCDT Lung in US

Oncimmune Holdings plc, a leading global immunodiagnostics group, announces it has entered into an exclusive partnership agreement which it believes will unlock the full potential of EarlyCDT Lung in the United States, bringing this lung cancer test to more patients as a result. This agreement with Biodesix, Inc., a leading lung cancer diagnostic solutions company, encompasses both the…

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New blood test

Reducing unnecessary ovarian cancer surgery

The majority of women who undergo surgery for suspected ovarian cancer do not have cancer. A novel blood test developed by researchers at Uppsala University and the Sahlgrenska Academy, University of Gothenburg, now offers the possibility of more precise diagnostics without the need for surgery. This could lead to a reduction in unnecessary surgery and to earlier detection and treatment for…

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Revolution through AI

Pixel analysis: the new era of digital pathology

As reporting workload for pathology departments continues to rise rapidly, artificial Intelligence solutions are set to play an increasing role in daily practice. In many pathology departments the annual number of cases has risen by around 2-4% but the slides produced has doubled in the last decade. Histopathologist Professor David Snead identified this phenomenon within his own centre in the…

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Urothelial carcinoma

AI assists in PD-L1 scoring

A new deep learning algorithm, which demonstrates the potential of artificial Intelligence (AI) to support pathologists, has been developed for PD-L1 scoring in tumour cells and immune cells in urothelial carcinoma samples. Speaking at the Digital Pathology and Artificial Intelligence Congress in London last December, Dr Michel Vandenberghe, from AstraZeneca, outlined how PD-L1 expression level…

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MERS-CoV

Seeking answers to combat Middle East respiratory syndrome

With a case fatality rate of 35 percent, a Middle East respiratory syndrome-related coronavirus (MERS-CoV) infection – also called camel flu – is a dangerous disease. About seven years ago, when the virus was first isolated, mortality was close to 100 percent since only severe infections that led to the patient being in intensive care were recorded. Today the environment of each victim is…

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Ultra-thin and polished

Next-generation objectives push boundaries of microscopy

Olympus has broken down barriers to imaging quality with the launch of its next-generation objectives. The breakthrough polishing technique enables the company to produce ultra-thin lenses that overcome the traditional trade-off between numerical aperture (NA), flatness and chromatic correction – enabling all three parameters to be significantly improved. Olympus has harnessed this proprietary…

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New at Science Park

OGT celebrates opening of new Cambridge site

Oxford Gene Technology (OGT), A Sysmex Group Company, has celebrated the opening of its new facility in Cambridge, UK. The opening ceremony, which took place at the company’s new premises on the prestigious Cambridge Science Park, was attended by the Department for International Trade (DIT) and local media as well as top-level representatives from OGT and its parent company, Sysmex Corporation.…

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