Laboratory/pathology

From clinical chemistry to digital pathology: Read more about how modern medical laboratories and procedures in pathology play a vital role in the detection and prevention of diseases and in medical research.

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News • NHS rollout

Liquid biopsy: new ‘blood test-first’ approach for lung cancer

A new ‘liquid biopsy’ test can help fast-track lung cancer patients to receive targeted therapy up to two weeks earlier, while helping avoid further tests and treatments including chemotherapy.

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News • Precision medicine

Melanoma: with 43,000 data points to tailored treatments

Using nine different molecular biological technologies, researchers were able to precisely measure the properties of a melanoma tumor in four weeks and enable a precise treatment decision.

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News • Stratification of TSCC immunotypes

Tongue cancer: Immune profiling for improved outcomes

Tongue squamous cell carcinoma, the most common type of oral cancer, is a challenging target for immunotherapies. Researchers now identified five immunotypes to better predict treatment response.

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Article • Digital pathology discussion panel

The AI tools pathologists want and need

The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at current and future technology options. The panel of pathologists, scientists and academics from Europe and the USA assessed the tools they currently use and are available to them, and those they would like to see available in the future as AI plays an increasing role in pathology.

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News • Barrier effect research

Using bacteria to improve microbiota resistance to pathogens

Microbiota composition can help prevent pathogenic bacteria from proliferating, known as the barrier effect. Now, scientists have identified seven bacteria involved, paving the way for new therapies.

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News • Early detection of life-threatening conditions

Newborn immune profiling to improve neonatal care

Newborns, especially those born prematurely, are vulnerable to conditions such as sepsis. A new device profiles an infant’s immune function from a single drop of blood to improve neonatal care.

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News • Promising protein analysis tool

New blood test to enable rapid diagnosis of rare genetic diseases

An Australian research team has developed a blood-based method of analysing thousands of proteins in a single, untargeted test. This potentially enables rapid diagnosis of many rare genetic diseases.

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Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…

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Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

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