Teams at Helmholtz Zentrum München, LMU Munich and the Technical University of Munich (TUM) have developed a new algorithm that enables automated detection of metastases at the level of single disseminated cancer cells in whole mice. Cancer is one of the leading causes of death worldwide. More than 90% of cancer patients die of distal metastases rather than as a direct result of the primary…
More than one in ten cancer patients do not die from their cancer but from heart and blood vessel problems instead, according to new research published in the European Heart Journal. For some cancers, like breast, prostate, endometrial, and thyroid cancer, around half will die from cardiovascular disease (CVD). Dr Nicholas Zaorsky, a radiation oncologist, and Dr Kathleen Sturgeon, an assistant…
Five talented robotics specialists were selected by an international jury for the finals of the Kuka innovation competition from among 30 applications from all over the world. For the first time, the focus was put on medical robotics and the topic of “Healthy Living”. Each of the finalists were provided with the sensitive Kuka lightweight robot LBR Med and a 3D vision system from Roboception…
Chemical analysis of blood samples, combined with an artificial intelligence program, could speed up the diagnosis of brain tumours, according to research presented at the 2019 NCRI Cancer Conference. Brain tumours tend to have ambiguous symptoms, such as headache or memory problems, and a brain scan is currently the only reliable way of diagnosing them. Researchers say their test, which works by…
A key mechanism controlling tissue structure, which could help identify drugs that make it harder for cancer cells to spread, has been identified by researchers at the Francis Crick Institute. The two studies, published in Nature Materials and PLOS Computational Biology, explain the mechanism that causes changes in the structure of tissues. Using experimental and computational biology, the…
Research by team at Brighton and Sussex Medical School (BSMS) showed that repeated exposures to dental X-rays may be associated with an increased risk of thyroid cancer and meningioma. About 3,500 new cases of thyroid cancer and 1,850 cases of meningiomas are diagnosed each year in the UK, and the incidence of both cancers has increased in many countries during the past three decades. For thyroid…
A team of researchers lead by Helmholtz Zentrum München and the University of Würzburg identified an enzyme as a novel and strong inhibitor of ferroptosis, the iron dependent form of cell death: ferroptosis suppressor protein-1, short FSP1. This protein is expressed in a variety of cancer cell lines and therefore represents an attractive drug target for cancer treatment. In fact, the first FSP1…
The results of a major study across 195 countries, presented at UEG Week Barcelona 2019, indicate that global death rates for pancreatic cancer and incidence rates for colorectal cancer both increased by 10% between 1990 and 2017. The Global Burden of Disease study, is the first to provide comprehensive worldwide estimates of the burden, epidemiological features and risk factors of a number of…
X-rays could be tuned to deliver a more effective punch that destroys cancer cells and not harm the body, researches from Kyoto University find. Gadolinium delivered into cancer cells releases killer electrons when hit by specially tuned X-rays. The approach, published in the journal Scientific Reports, could pave the way towards a new cancer radiation therapy. “Our method opens up the…
A robot-controlled laboratory where decisions are made by artificial intelligence will change the way new drugs are discovered, says a leading researcher. The engineer leading a project to develop a prototype "lab-bot" says it will reduce the time it takes to identify and synthesise molecules for new medicines – a process that can take years as scientists refine the shape and property…
Most people can continue to eat red and processed meat as they do now. A major study led by researchers at McMaster and Dalhousie universities has found cutting back has little impact on health. A panel of international scientists systematically reviewed the evidence and have recommended that most adults should continue to eat their current levels of red and processed meat. The researchers…
Researchers at Leipzig University and Leipzig University Hospital (UKL) have discovered that tumour growth and tissue invasion by cancer cells can be predicted based on the ontogenetic distance between tissues.
Cancer treatment could be dramatically improved by an invention at the University of Waterloo to precisely locate the edges of tumors during surgery to remove them.
Lymphomas in the central nervous system are rare but dangerous. Scientists at the German Cancer Research Center (DKFZ) have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous system.
Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments. Researchers based at The University of Manchester have discovered a new strategy for how to protect hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss – arguably one of the most…
Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University (Finland) and Huazhong University of Science and Technology (China) have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for efficient cancer chemotherapy. Exosomes contain various molecular…
The Geneva University Hospitals (HUG) is the first European university hospital to utilize IBM’s artificial intelligence (AI) technology to help uncover therapeutic options for cancer patients. HUG will use the IBM Watson Health’s precision oncology offering, Watson for Genomics, an AI tool that enables oncologists to provide patients with more personalized, evidence-based cancer care. Using…
Cancer of unknown primary (CUP) can send radiologists on a frustrating scavenger hunt: metastases were detected but the primary cancer is nowhere to be seen. Professor Alwin Krämer, Head of the Clinical Cooperation Unit Molecular Haematology/Oncology at University Hospital Heidelberg and the German Cancer Research Center, explains strategies for dealing with CUP.
Levels of molecules associated with genetic function, such as microRNA, can be an important indicator of abnormal activity associated with cancer. However, little is known about how different molecules are altered in cancerous cells. Now, researchers from Japan have found a new way of distinguishing cancerous from non-cancerous tissues. In a study published in Nature Communications, researchers…
The latest study by the German Society for Haematology and Oncology (DGHO), ‘Prognosis for population-based morbidity for common cancers in Germany – impact on provision’ has made it clear that due to demographic developments in Germany and to medical advances in oncology, the requirements for cancer patients’ care are ever more diverse. The increase in newly diagnosed cancer patients is…
In terms of success in revolutionary cancer treatment, molecular genetic examination procedures have developed immensely over recent years. They now range from conventional polymerase chain reactions (PCR) or fluorescence-in-situ hybridisation (FISH) to Next Generation Sequencing (NGS) with analysis of the entire exome or genome (Whole-Exome, WES or Whole-Genome, WGS) and of the transcriptome…
Professor Regina Beets-Tan has been appointed to the mission board of the EU research mission on cancer, part of the European Commission’s research initiative known as Horizon Europe. She has been selected to serve on the 15-member board for the cancer mission, tasked with shaping their mission and further defining what research receives funding within the cancer mission’s mandate, beginning…
Two known gene mutations induce pathways that enhance pancreatic cancer’s ability to invade tissues and evade the immune system. Researchers report the molecular details of this process providing insights into druggable targets for immunotherapies. Mutations in the genes KRAS and TP53 are closely linked to pancreatic ductal adenocarcinoma, by far the most common type of pancreatic cancer.…
Researchers from Northwestern University are using Argonne supercomputers to advance the development of an optical microscopy technique that can predict and quantify cancer risks at extremely early stages. The basic principle driving Allen Taflove’s computational electrodynamics research — which bears the potential to transform how we diagnose, and possibly treat, various forms of cancer —…
Researchers identified how to kill therapy-resistant cells in hypoxic tumors and in cells arising in the von Hippel-Lindau hereditary cancer. In a recent publication in PNAS, the research group identified how to kill therapy-resistant cells in hypoxic tumors and in cells arising in the von Hippel-Lindau (VHL) hereditary cancer.