Cancer

From solid tumors to metastatic carcinomas and leukemia: cancer is among the most common causes of death and has many faces. Keep reading for latest developments in early detection, staging, therapy and research.

News • Unexpected similarities

Different tumours, same origin: Surprising discovery in paediatric brain cancers

Researchers discovered that pineoblastoma, retinoblastoma and medulloblastoma – severe brain tumours in children that appear to be completely different – actually arise from the same type of cell.

News • Conditioning against cardiotoxicity

Chemotherapy: protecting the heart without compromising anticancer efficacy

Researchers have discovered a new way to protect the heart during cancer chemotherapy without reducing antitumor efficacy. This could reduce long-term cardiovascular complications for patients.

Article • Equity, access, and the future of radiotherapy

Radiation oncology: the beam widens

Radiation oncology is a field in remarkable transformation: a deepening global shortage of trained practitioners, persistent inequities in access to treatment – and, on the other side of the…

News • Liquid biopsy screening tool

AI metabolomics platform to advance pancreatic cancer early diagnosis

Pancreatic cancer remains a diagnostic challenge, due to unspecific early symptoms and lack of effective screening tools. A novel AI metabolomics platform could help overcome these issues.

News • At least 18 years of reduced risk

Cervical cancer: study confirms long-term protection from HPV vaccination

Vaccination against human papillomavirus (HPV) reduces the risk of cervical cancer for at least 18 years, according to a new study. There were no signs of waning protection over time.

News • Biomarker-agnostic detection

Electronic nose uses AI to “smell” ovarian cancer

Using machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers.

News • (B)eating cancer

Bacteria to consume tumours from the inside out

A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out.

News • Treatment approach

How to improve cancer cure rates? “Kick it while it’s down”

Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first.

News • Cancer “chronotherapy”

Beating cancer by the clock: Why the time of day matters for radiotherapy

Radiotherapy is more effective when administered at the right time of day, according to new research. This discovery opens the door to cancer “chronotherapy”, the researchers hope.

News • AI detects unseen connection

Insulin resistance identified as risk factor for cancer

Not just linked to diabetes: For the first time, researchers demonstrated that insulin resistance is a risk factor for 12 types of cancer, including uterine and breast cancer.

Article • Digital pathology and AI

Finding new biomarkers to match the biological complexity of cancer

Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…

News • Research on metastasis mechanism

How ovarian cancer hijacks abdominal cells as an invasion force

Due to its rapid spread in the abdomen, ovarian cancer is often only detected at an advanced stage. Now, scientists have discovered how this cancer takes advantage of other cells for metastasis.

News • CTNNB1 in focus

Mutation strength may hold key to personalized cancer treatment

Not all cancer mutations are equal: new research shows that a single mutation hotspot can generate a rich diversity of tumour behaviours. This could lead to more personalised cancer treatments.

News • Two tracers, one target

Dual PET approach for personalized head and neck cancer treatment

Beyond "one-size-fits-all": A new strategy that combines two types of PET scans can guide personalized radiotherapy for head and neck cancers, according to new research.

News • PRO in oncology

Giving patients a voice: How self-reported data improves cancer treatment

Integrating the patient’s voice: A new study shows access to patient-reported outcome (PRO) data improves the consistency of the evaluation of treatment-related side effects in patients with cancer.

News • Soft tissue ablation

Adapting eye-laser technology to remove cancer

Scientists have shown that a type of laser similar to the one currently used in routine eye surgery could one day help surgeons remove unwanted tissues, such as tumours, with unprecedented accuracy.

News • Exploring metastatic potential

AI predicts risk of cancer metastases

Why do some tumours spread while others remain localised? Using colon cancer cells, scientists pinpointed the criteria that influence metastasis risk, and identified a way to assess its probability.

News • Plasma protein profiling

Blood test spots cancer in patients with unspecific symptoms

Non-specific symptoms such as fatigue, pain or weight loss can be caused by cancer, another serious condition or something completely harmless. A blood test can help provide relevant information.

News • Systemic mechanism discovered

Chemotherapy rewires gut bacteria to curb metastasis

Chemotherapy does more than kill cancer cells: It reshapes the gut microbiome, making the body less permissive to metastasis. This finding opens new avenues for adjuvant strategies.

News • Anthracycline cardiotoxicity

Common chemo drug increases risk of heart damage, study finds

A widely used chemotherapy drugs used in cancer treatments can cause heart damage, new research shows. This could be used to adapt treatment regimens - especially in patients with high blood pressure.

News • Focus on tumor STAT1 acetylation

How cancer cells learn under pressure to evade immunotherapy

Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.

News • Phase III trial

Proton therapy shows survival benefit for patients with head and neck cancers

A new study shows a significant survival benefit for patients with oropharyngeal cancers treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).

News • Clinically validated framework

AI helps detect kidney cancer faster

A novel machine-learning-based solution analyses CT images and helps radiologists detect both malignant and benign lesions in the kidney more quickly and reliably.

News • Tissue sample analysis

Demographic bias creeps into pathology AI, study finds

A sample of inequality: A new study shows that AI models can infer demographic information from pathology slides, leading to bias in cancer diagnosis among different populations.

News • Prevalence, changes and associated factors

How to reduce the risk of head and neck lymphedema after radiotherapy

Researchers have discovered that low physical activity is associated with a higher risk of lymphedema. They have also noted that a lymph scanner objectively measures changes in the condition.

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