Networks of certified cardiac arrest centres could dramatically improve survival and neurological outcomes for patients who suffer out-of-hospital cardiac arrest. At the ESC 2026 congress in Munich, experts debated how hub-and-spoke models in acute cardiovascular care can standardise treatment – not only for cardiac arrest, but also for pulmonary embolism and cardiogenic shock.
A research team has developed a new class of protein-based MRI contrast agent that detects invasive lung cancer and metastatic disease at earlier stages than conventional imaging approaches.
Radiotherapy may be able to do far more than simply destroy tumor cells. A review explores how combining radiotherapy with immunotherapy could improve outcomes for patients with pancreatic cancer.
Findings of a new study suggest that changes in the gut microbiome could be linked to Parkinson’s disease and may eventually help researchers identify new underlying mechanisms for the condition.
Cardiovascular disease remains the leading cause of death across the EU, cutting short the lives of millions of Europeans every year, and placing an enormous strain on health systems and economies alike. Yet prevention and early intervention can have a major impact – and this is precisely the ambition of the EU Safe Hearts Plan. At a high-level event at the European Parliament in Brussels in…
From tissue heating to image artifacts – implants were once considered an absolute contraindication to MRI. Modern implant design and evolving safety standards have changed that picture considerably – yet misconceptions persist, even among imaging professionals. At the European Congress of Radiology (ECR) in Vienna, a dedicated session set out to address those misconceptions head-on.
On the way to a patient's “digital twin”: A novel, AI-powered virtual patient simulation system integrating multimodal data is designed to advance personalised cancer treatment.
Researchers identified a possible biomarker linked to severe suicidal thoughts. It may also help explain why some people recover, opening a new path for research into resilience and prevention.
Blood tests yield vital information about Alzheimer’s disease. However, new research suggests that relevant biomarkers may differ significantly across patient populations.
More biomarkers for better insights on Alzheimer's disease: a new study explores how a panel of seven proteins could help predict disease progression and inform more accurate treatment choices.
Invasive fungal infections are notoriously hard to catch early, and even harder to rule out with confidence. At CHU Bordeaux, Dr Frédéric Gabriel has spent years refining how his lab uses β-D-glucan (BDG) testing to sharpen that judgement call – including with the Wako β-glucan test. In this interview, he explains what the guidelines say, what actually happens at the bench, and where he…
A diffusion MRI metric can detect changes in white matter tracts not visible on conventional MRI – this could help identify early abnormalities in the brain associated with Alzheimer’s disease.
Antimicrobial stewardship is essential to curbing the growing threat of drug-resistant infections – yet its principles are too often abandoned the moment a patient leaves the intensive care unit (ICU). At the Critical Care Symposium in Manchester, Professor Marc Leone outlined why consistent antibiotic management across the entire hospital stay is vital for patient outcomes.
A new study has identified a way to reshape the gut microbiome that can enhance the delivery of certain chemotherapies to tumors, making these nanoparticle-based cancer drugs more effective.
PET/CT can add valuable information to aid the diagnosis of fever of unknown origin (FUO), directly influencing the clinical management in nearly 75% of patients, a new study finds.
Chemotherapy of many childhood cancers leaves specific traces in the DNA, a new study finds. These changes could help clinicians spot treatment resistance earlier, before cancer returns or spreads.
Low brain metabolism as measured from 18F-FDG PET/CT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research.
What happens in the brain during anaesthesia? A novel brainwave monitoring method could help lower the risk of intraoperative awareness, postoperative delirium, and long-term cognitive decline.
As the aorta gains recognition as a functioning organ rather than a simple blood conduit, the lack of standardised imaging protocols is becoming an increasingly pressing concern. At ECR 2026 in Vienna, Professor Nicola Galea from Sapienza University of Rome made a compelling case for unified imaging approaches, warning that inconsistency in measurement techniques can lead to flawed clinical…
The presence of certain bacteria in the gut microbiota, and fluctuations in a person’s metabolism, have been identified as potential biomarkers for type 2 diabetes years before its onset.
The microbes living in the human gut influence metabolism, immunity, and cardiovascular health. A new study now suggests they may also be closely connected to Alzheimer's disease.
Why do some prostate cancers grow slowly and remain localized while others become aggressive and metastasize? In a new paper, researchers identify the answer: tumor methylation.
AI models can now assess breast cancer risk directly from changes in screening mammograms over time, a new study shows. This opens the door to a new era of dynamic breast cancer risk assessment.
Measuring radiodensity of visceral fat and muscle from CT scans, researchers have identified a new biomarker that may help determine the prognosis for patients with gastric cancer.
A new high-res PET scanner is making its clinical debut at UZ Leuven. The scanner makes it possible to detect earliest signs of brain diseases, years before a patient experiences the first symptoms.
Advanced multiparametric MRI performed before kidney tumor surgery could help identify patients at higher risk for kidney function decline and chronic kidney disease after nephrectomy.
Invasive fungal infections are silent, fast-moving, and notoriously hard to catch in time. The FUJIFILM Wako β-D-Glucan Test on the LIMUSAVE MT-7500 gives clinical laboratories a quantitative, LAL-based tool to detect (1→3)-β-D-glucan in serum or plasma – enabling earlier diagnosis where it matters most.
A new AI-based method can reduce the time required for certain MRI brain scans by up to 90% while maintaining a high level of accuracy, paving the way for more efficient and accessible neuroimaging.
Persistent long Covid symptoms are often linked to brain inflammation. However, results from a new study point at a different explanantion for fatigue, cognitive impairment, anxiety, and depression.
Due to advances in radiation therapy, some breast cancer patients may be able to omit surgery following ablative radiation, according to new results of a Phase 2 trial.
A new study shows that diaphragmatic dome height (DDH) - a simple measurement from routine chest X-rays - can help predict survival among patients with lung cancer and breathing disorders.
A new microscopy method reads lipids' natural spectral fingerprints using mid-infrared light and ultrasound – no fluorescent labels needed, less stress for living cells.
Researchers have developed an electrochemical sensor that can detect pancreatic cancer in its early stages. The device offers a simpler, more affordable alternative to conventional tests, which are less accessible.
A 3D brain marker may help identify which patients with idiopathic normal pressure hydrocephalus (iNPH) benefit from shunt surgery – improving outcomes and sparing others from ineffective treatment.
Not all precancerous lesions will develop into tumours, yet the majority are treated as if they were already breast cancer. A new marker could help identify the relevant cases and avoid overtreatment.
A compact LED module pairs UV-A, green and IR light with a matched photodiode to detect AGE autofluorescence — bringing biochemical risk screening to wearables and point of care testing.
A multidisciplinary team of pathologists, oncologists and biologists has discovered a new biomarker to determine whether immunotherapy may work in people with colon and rectal cancer.
AI models can generate more complete summaries of complex cancer pathology reports than physicians, according to a new study that tested six models developed by Meta, Google, DeepSeek and Mistral AI.
Researchers have developed a new MRI-based method that enables objective quantification of the growth of the most aggressive brain tumours, particularly glioblastoma.
Digital spatial profiling (DSP) is emerging as a powerful technology in helping specialists investigate complex kidney disease, according to a leading expert. Professor Renate Kain believes spatial profiling adds significantly to systems biology approaches that will transform diagnostic histopathology. However, she warns that the adoption and effective utilization of the technique is critically…
A biomarker discovered in the cerebrospinal fluid could improve diagnosis of Parkinson's disease and dementia with Lewy bodies.
Siemens Healthineers has announced the availability of two blood-based biomarker tests for research use: the Atellica IM Phosphorylated tau 217 (pTau217) and the Atellica IM Brain Derived Tau (BDTau) assays. Both are run on the Atellica Solution IM and Atellica CI Analyzers.
A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research.
Functional brain radiosurgery is an application of stereotactic radiosurgery (SRS), representing its newest clinical field. It is a precise, non-invasive medical technique using focused ionising radiation to precisely target specific brain structures to modulate brain function for neurological disorders, psychiatric conditions, or intractable pain. The technology offers “precision without…
Pancreatic cancer remains a diagnostic challenge, due to unspecific early symptoms and lack of effective screening tools. A novel AI metabolomics platform could help overcome these issues.
To better distinguish between healthy and diseased gut microbiomes, scientists have created an index that tracks microbial behavior and signals conditions such as colorectal cancer.
Using machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers.
Researchers at Karlsruhe Institute of Technology (KIT) have developed an AI model to predict how well patients with hip osteoarthritis will be able to walk again after an operation.
Advances in artificial intelligence and multimodal data integration are poised to revolutionise cancer diagnostics – but significant challenges remain before these technologies can be routinely deployed in clinical practice. Professor Manuel Salto-Tellez outlined the steps needed to bridge the gap between complex tumour biology and the relatively simple biomarkers currently available, speaking…
Researchers report on decisive steps towards an early diagnosis of Parkinson’s disease: a newly discovered biomarker in the blood could open a window of opportunity for future treatment.
Computational pathology is becoming increasingly important in helping deliver precision medicine to a wider range of patients. Experts at the 37th European Congress of Pathology in Vienna discussed how algorithms can optimise laboratory workflows, generate stronger evidence for molecular tumour boards, and enhance clinical trial design.
A new study into the long-term health impacts of coronavirus has found changes in the blood after Covid-19 that might pinpoint patients at risk of ongoing lung disease.
Analytical and measurement technology copany Horiba has obtained CE IVDR certification for its new Yumizen H500 CRP benchtop hematology analyzer, designed for small laboratories.
Non-invasive, millimetre-scale diffusion MRI (dMRI) can be used to detect morphological changes in axons – a common hallmark of a wide range of neurological disorders, new research shows.
Immunotherapy has been hailed as a breakthrough in cancer treatment. But new research reveals: under sustained treatment pressure, cancer does not simply weaken — it adapts, learns, and fights back.
An international study shows that Alzheimer’s disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to a laboratory.
A new University of Toronto-led study has discovered a possible biomarker linked to multiple sclerosis (MS) disease progression that could help identify patients most likely to benefit from new drugs.
Cardiovascular disease and depression do not co-occur by chance; the TO_AITION project aims to enable earlier diagnosis of comorbidity, better risk prediction and personalised treatment strategies.
A simple blood test that can very accurately predict the chance of survival with good recovery could be of great significance for patients in intensive care after a cardiac arrest.
Radiotherapy is effective against prostate cancer but can cause side effects. Using AI, scientists found that images originally taken to help position patients could also predict rectal bleeding.
Even minor functional impairments of the kidneys can have serious consequences for patients after major surgery. New biomarkers could help identify high-risk patients at an early stage.
Depression is not only a disease of the mind or the brain, a new study finds: a research team has revealed deep connections to abnormalities in the body's overall immune response.
A major new initiative aims to enable the development of advanced, specific and highly reproducible human in vitro models for greater understanding of disease and the acceleration of new medicines.
Philips and Cortechs.ai have extended their collaboration to integrate AI-enabled quantitative neuroimaging analytics directly into MR systems. The partnership aims to provide radiologists with automated, objective measurements of brain structures and lesions to support diagnosis and monitoring of neurological conditions.
New research reveals why women with long Covid — especially those who develop chronic fatigue syndrome — tend to experience more severe and persistent symptoms than men do.
A biosensor that identifies volatile organic compounds (VOCs) in exhaled breath could be used in conjunction with AI to detect various thoracic cancers including lung cancer.
In emergency settings, AI to analyze ECG data can improve detection of severe heart attacks, including those with unconventional symptoms, or atypical ECG patterns, and reduced false positives.
Biomarker testing is ushering in a novel era of therapy personalisation for gastroesophageal and colorectal cancers, according to experts presenting at the 37th European Congress of Pathology in Vienna this September. During a session on state-of-the-art in gastrointestinal biomarkers, speakers outlined how targeted therapies and immunotherapies are transforming treatment options – but…
Newly discovered blood biomarkers may offer new options to track Duchenne muscular dystrophy (DMD) in a less invasive way than physical tests or biopsies. This could support more tailored treatments.
New cardiac imaging techniques continue to uncover the secrets of the heart for cardiologists who know how to use them. At the ESC 2025 Congress in Madrid, four experts explored cutting-edge developments across different modalities. These novel approaches provide a promising glimpse of what the next generation of cardiac imaging is capable of.
Chronic fatigue (ME/CFS) affects millions worldwide, but is poorly understood and has long lacked reliable diagnostic tools. Now, a new blood test claims to diagnose the condition with 96% accuracy.
Using PET/CT imaging, researchers discovered that the biological activity of visceral fat may drive the progression of endometrial cancer, offering a novel angle for diagnosis and treatment.
New insights on the mechanisms that cause “brain fog” in Long Covid patients: Researchers use a specialized brain imaging technique to identify a potential biomarker and therapeutic target.
International research led by Leipzig and Ulm universities creates first standardized leptin reference values for all ages and weight classes, advancing personalized medicine
Scientists created precise replicas of Candida sugar coats to understand immune responses, enabling fast bedside testing that could replace slow lab cultures.
Researchers explored two promising new biomarkers as potential radiotheranostic targets for endometrial cancer. This could help identify patients who are likely to respond to targeted therapeutics.
Researchers have developed a machine learning algorithm that uses cardiac MRI images to help identify breast cancer patients who may be at risk of cardiotoxicity during cancer treatment. The research, led by cardiologist Dr Paaladinesh Thavendiranathan, was presented at the European Society of Cardiology's Cardio-Oncology Conference in Florence in June.
Self-learning artificial intelligence approaches are offering a number of advantages for digital pathology when compared to established AI options. The benefits, which range from greater speed and capacitive flexibility to ‘wholly interpretable’ analyses, were outlined at the Digital Pathology and AI Congress in London.
The mere fact of being exposed to a sick avatar in a virtual reality environment triggers a measurable immune response in humans, a multidisciplinary research team discovered.
Remote monitoring via microfluidic platforms, AI-assisted sensor systems, and more: Attendees of the Labmed Forum at Medica saw impressive examples on how wearable technology is becoming a transformative force in laboratory medicine to improve real-time monitoring of patients, covering widespread conditions such as diabetes, asthma and COPD. With an emphasis on remote monitoring, devices are…
The vaginal microbiome is a largely overlooked area of medicine that could dramatically improve outcomes for common infections, infertility and even cancer for millions of women, a new review finds.
Type 2 diabetes greatly increases the risk of heart attacks, strokes, anginas, and other coronary heart diseases. Therefore, biomarkers to predict individual risk are needed, experts say.
A multicenter study involving leading hospitals across Spain, has confirmed that people with COPD show altered levels of specific metabolites in their blood.
Do laboratory tests using blood-based biomarkers (BBB) represent the next type of universally recommended screening tests for Alzheimer's disease (AD)? Experts curb the high expectations for this type of diagnostic tool.
Tumor vesicles may serve as early indicators of cancer and help monitor the effectiveness of treatments. Now, researchers discovered a new way to detect these vesicles.
Defining four different immunologic subtypes of recurrent ovarian cancers, researchers pave the way for more personalized treatment.
Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to Covid-19 home tests, according to University of Michigan researchers.
Using electrodes implanted in the brain, researchers observed specific brain waves that could serve as a biomarker for obsessive-compulsive disorder (OCD) and are an important step towards more targeted treatments.
By identifying the unique biological signatures that guide AI tissue classification, new research lays the foundation for smart surgical tools with the added feature of biomolecular-level precision.
Two dogs have been trained to distinguish between sebum swabs from people with and without Parkinson’s disease. This is especially relevant, as a definitive diagnostic test remains elusive.
The earlier Alzheimer's disease is detected, the more effective treatments become. Now, a Finnish study shows that signs related to Alzheimer’s may already be found in the brain in middle age.
More consistent TIL assessments, more accurate patients' prognoses: New research shows how AI sharpens pathologists' interpretation of tissue samples for malignant melanoma.
Molecular markers in saliva could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases, new research finds.
What do the brains of newborns and patients with Alzheimer's disease have in common? Researchers have discovered a surprising shared trait - which might provide new insights into the disease.
New research makes a strong case for a new dual-targeting radiopharmaceutical, designed to attach to two vulnerable sites on cancer cells, enabling more precise and potent therapy.
New research demonstrates CT colonography outperforms stool DNA testing in both clinical effectiveness and cost savings for colorectal cancer screening.
In a world first, researchers have identified a set of biomarkers that could someday make it easy to spot Parkinson's disease in a patient’s blood sample.
Microbiota composition can help prevent pathogenic bacteria from proliferating, known as the barrier effect. Now, scientists have identified seven bacteria involved, paving the way for new therapies.
Results of a new retrospective study demonstrate the potential of a novel, CT-based deep learning-driven tool to enhance liver cancer diagnosis, treatment planning, and response evaluation.
Researchers from Université Laval discovered that the retina of people with Parkinson's disease responds differently to light than that of healthy people. This offers new diagnostic options.
A new biomarker for multiple sclerosis: the inflammatory cell rim from microglial cells surrounding brain lesions was found to directly correlate with the severity and speed of disease progression.
Pupil dilation and involuntary facial movements could provide a window into diagnosing tinnitus. A new method uses AI to detect minuscule reactions to various sounds and noises.
Using AI and extensive analyses of gene activity in tumours, researchers have found new, precise biomarkers to diagnose prostate cancer at an early stage through a simple urine sample.
Breast MRI has emerged as a powerful diagnostic tool, particularly for women with dense breast tissue where traditional mammography faces limitations. In her presentation at ECR 2025, radiographer Hanna Kalliomäki highlighted several technological advances transforming breast cancer detection and diagnosis. From time-saving abbreviated protocols and AI-assisted analysis to contrast-free…
A new, simpler and cheaper analytical method for the early detection of Alzheimer's disease could help bring blood tests into the healthcare system globally, according to a new study.
A new study found that a significant proportion of Parkinson's disease diagnoses are later corrected. The results demonstrate the need for improved diagnostic processes.
An international research team has developed an intelligent device capable of monitoring the skin continuously and accurately detect temperature variations associated with inflammation and infection.
The evolving role of AI tools in digital pathology was explored at an open discussion during the annual Digital Pathology and AI Congress in London with a high-level panel of practitioners looking at current and future technology options. The panel of pathologists, scientists and academics from Europe and the USA assessed the tools they currently use and are available to them, and those they…
Using the COX-2 enzyme, a new PET imaging approach offers a never-before-seen view of inflammation in the brain, opening the door for clinical and research settings for various brain disorders.
A large new study of more than 40,000 patients finds that a zero coronary artery calcium score continues to be an accurate indicator of a low risk for a coronary heart event even as a person ages.
New findings show how AI-assisted mammography may not only reveal breast cancer, but can also assess calcium buildup in the arteries within breast tissue—an indicator of cardiovascular health.
A new PET tracer has the potential to play a critical role in the diagnosis, treatment, and monitoring of aggressive triple-negative breast cancer (TNBC), improving clinical outcomes for patients.
There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers, quantifiable characteristics of biological processes or pathological conditions of the body, are making it possible to help identify and measure the presence and extent of AD and its degenerative…
Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…
Around one third of people with cardiovascular disease (CVD) also have mild cognitive impairment (MCI), yet the condition is often undiagnosed. A new project aims to untangle this MCI-CVD connection.
A new blood test, using neurofilament light chainproteins as biomarker, could lead to better diagnosis and management of amyotrophic lateral sclerosis (ALS).
The boom in interventional radiology procedures has enabled great strides in ischemic stroke management. But while a myriad of techniques are available, the challenge remains in choosing the most appropriate thrombectomy treatment on the spot, according to Jordi Blasco Andaluz, a neuroradiologist at Hospital Clinic Barcelona. The new ROSSETTI registry is designed to change this.
New research highlights the potential of circulating tumor DNA (ctDNA) analysis as a non-invasive method to identify actionable biomarkers for breast cancer, enabling individualized therapies.
The discovery of a 'biomarker panel' could have a profound impact on the ability to identify patients at risk of developing pancreatic cancer at an earlier stage, researchers hope.
Using a new technology and computational method, researchers have uncovered a biomarker capable of accurately predicting the aggressiveness of meningioma brain tumors and breast cancers.
Researchers have created a landmark atlas of how healthy breast tissue ages, revealing key cellular, molecular, and genetic changes that may tip the balance toward breast cancer development.
Researchers have developed a new kind of tumour-on-a-chip, which gives insight into the tumour environment and immunotherapy response. The device has been successfully tested on breast cancer samples.
Certain gene alterations can serve as a prognostic and predictive biomarker for prostate cancer. Now, researchers confirm the feasibility of using NGS on this marker for precise patient stratification and treatment selection.
A sensor, similar to glucose monitoring devices, detects lung cancer biomarkers from a blood sample in just 40 minutes. The technology has potential to identify at-risk patients and tailor treatments.
By analysing the largest collection of whole-genome data from osteosarcoma patients, researchers identified a driving mechanism behind the aggressive development of these bone cancer tumours.
Tongue cancer cells can become resistant to chemotherapy under certain circumstances. Investigating these mechanisms, researchers shed light on promising avenues toward new treatments for this cancer.
Researchers have developed an AI-based model to better predict whether cancer patients will benefit from immunotherapy — using only routine blood tests and clinical data.
Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of breast cancer chemotherapy while reducing its harmful side effects.
Complex diseases could require complex biomarkers for accurate diagnosis in the years ahead, according to a leading pathologist. In a keynote address to the 36th European Congress of Pathology in Florence, Italy, Professor Manuel Salto-Tellez highlighted this as one of the major future challenges for the discipline. However, he also believes pathologists will sit at the core of modern medicine.
Research offers new insights into harnessing the immune system to combat ovarian cancer. The findings could lead to personalized therapies that target the right patients at the right time.
Spinal cord stimulation is performed for patients with chronic pain. However, for some patients, the procedure is not effective. A new method involving fMRI could help predict success.
Precise segmentation of anatomical structures greatly benefits cancer diagnosis. Using AI and deep learning methods, researchers are developing a high-precision 3D viewer software for medical image data.
US researchers have developed a comprehensive deep learning AI model designed to more accurately identify and classify cells in high-content tissue images.
New research highlights the potential of liquid biopsy in diagnosing pancreatic incidentaloma - lesions which can occasionally signal pancreatic cancer in its earliest stages.
Molecular pathology should become centralised in fewer labs to improve efficiencies and affordability, according to leading European experts.
How can innovations help to master challenges and demands in healthcare? This central question will be addressed at the Medica Health IT Forum, an established part of the programme at the trade fair.
Multiplex imaging can play a critical role in unravelling the tumour microenvironment. The potential and benefits of the emerging approach – a way to extract information from human tissue samples by visualising many more biomarkers than traditional microscopy – was highlighted in presentations during the 36th European Congress of Pathology in Florence, Italy. Speakers also discussed novel…
A new method could open new avenues to quick, affordable cancer diagnosis, US researchers report. The method uses ultrathin membranes to capture extracellular vesicles.
Taipei City is set to make a splash at the Medica 2024 trade fair. The city's Department of Economic Development has curated an exhibition area, featuring six innovative biotech companies.
Immunotherapy has become the most promising strategy for treating several cancers, but its effectiveness is still very uneven. Three researchers explain how research is being done to change this.
A new study found that measuring circulating tumor cells (CTCs), rare cancer cells shed from tumors into the blood, is a reliable way to predict later treatment response and survival prospects with metastatic prostate cancer.
Before administering certain drugs, doctors check a patient’s kidney function by testing their blood urea nitrogen and creatinine levels. New research shows that gold nanoparticles might give more accurate results.
A new study confirms fibrosis as a prognostic indicator in HER2-negative, the most common breast cancer, and opens the way to antifibrotic drug treatments.
Researchers have identified biomarkers that, in conjunction with PET imaging, enable doctors to reliably distinguish between primary 4-repeat tauopathies and Alzheimer's disease.
Only 20-40% of patients respond positively to immunotherapy, and these rates vary across different types of cancer. Researchers now identified five key factors that determine response and survival.
Radiologists and gynaecologists entered a veritable bout during the Oxford debate at the 43rd annual congress of the German Senologic Society in Dresden. Controversy was sparked by the question of whether all patients with a ductal carcinoma in situ (DCIS) should undergo radiotherapy.
Endometriosis can cause abdominal pain and cramping before, during and after menstruation, and may lead to infertility. Now, researchers identified promising approaches for better early diagnosis.
Can a mouthwash-based test help predict head and neck cancer recurrence? A new study suggests it might.
Using conventional ultrasound, researchers have developed a model that determines whether conditions such as fibrosis or edema are present in the lungs, and gives information about the severity.
A new method could lead to a significantly more precise and reliable diagnosis of pancreatic cancer. It is based on the selective detection of specific antibodies in blood samples.
Just a concussion? Head injury can lead to persistent symptoms, yet CT scans often fail to identify these cases. Researchers explore the potential of diffusion tensor imaging for better diagnostics.
Researchers at MIT and ETH Zurich developed an AI model that identifies certain breast cancer stages likely to progress to invasive forms of cancer.
Diagnosis and monitoring medical conditions, including cancer, diabetes, heart disease, and infections: In this opinion article, Alix Joseph (Linxens) explores the potential of sweat analysis.
Ductal Carcinoma in Situ (DCIS) often develop into more invasive forms of breast cancer. To predict which DCIS patients are likely to be affected, researchers have developed an analytic AI-based tool.
Researchers have developed a model to predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease. The next step is an app that uses this model.
Microproteins hold great promise, according to new research: Since they are only expressed by liver tumor cells, the proteins could serve as a potential target for cancer vaccine development.
A new study shows that extracellular vesicles shed by prostate cancer cells contain tumor-derived material that can be used as biomarkers of therapy response and resistance in metastatic disease.
Why does obesity increase the risk of cancer and possibly metastasis? Researchers in Spain are currently investigating this very question.
Researchers have developed an AI model that increases the potential for detecting cancer through sugar analyses. The AI model is faster and better at finding abnormalities than current methods.
A novel blood test shows promise to predict Parkinson's disease in risk patients up to seven years before the typical motor symptoms appear.
Tackling standardization of molecular pathology at a European level remains a major challenge, according to speakers at the 35th European Congress of Pathology in Dublin. One leading expert warned it would be ‘very difficult’ to achieve, though the session also heard about potential solutions such as educational steps to consistently train future pathologists at a high and consistent level.
Digital twin technology can transform clinical practice by aiding patient-specific prediction and supporting personalized treatment models. Expert speakers at an ECR 2024 session in Vienna focussed on how radiology will play a leading role in the advance through data acquisition via a range of imaging modalities.
Pancreatic cancer stem cells exploit an antibacterial protein to evade the immune system. Removing this protein could pave the way to more effective immunotherapy, new research suggests.
A research group established a microfluidic control technology that can be applied to small blood testing devices and consequently developed a novel integrated immunoassay device.
Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A research team developed a new method to predict which patients will benefit from it.
Tissue biopsy and liquid biopsy can increasingly be used as complementary or alternative approaches, with advantages and limitations to each. While speakers at the recent 35th European Congress of Pathology in Dublin were quick to highlight that liquid biopsy was not about to replace tissue biopsy, the focus looked at the benefits and challenges of each through the lens of four expert speakers.
Structural differences in male and female brains might explain why women are more prone to concussions and experience longer recovery from the injury than men, according to a new preclinical study.
Endoscopy is pivotal in diagnosing and managing ulcerative colitis. Recent technology advances allow for early cancer detection, precise disease assessment and targeted biopsies, improving diagnosis and monitoring. The following article takes a look at the latest advancements.
Adding a new dimension to pathology: Researchers explore new, deep learning models that can use 3D pathology datasets to make clinical outcome predictions for curated prostate cancer specimens.
Coronary artery disease causes more than 1.8 million heart attacks each year in Europe. In most cases, rehabilitation helps the patients to return to their everyday life. But what happens once the patients have left the rehab clinic?
US researchers have developed and validated a new urine-based test for prostate cancer, which was shown to meaningfully reduce unnecessary prostate biopsies while providing highly accurate detection.
New research provides cause for optimism that long Covid can resolve over time. Following people from the first wave of Covid-19, it monitored the longevity of immune abnormalities after an infection.
Digital pathology can be used to great effect in pharmaceutical research: it can accelerate analyses, give deeper insights into cellular mechanisms, and enable better understanding of their role into clinical development. This potentially offers clearer predictions on how patients may respond to treatment and lead to personalized therapies.
New approaches to cardiovascular radiology are evolving to help clinicians gain an increasingly better insight into heart conditions. Latest developments in cardiovascular radiology include myocardial strain imaging, 4D flow and photon-counting CT technology. An ECR 2024 session shone the spotlight on these areas of cardiovascular imaging with expert speakers outlining the pros and cons of each.
A new detection tool is designed to contribute to improving tumour research and classification by identification and quantification of chromosomal instability in the nuclei of cancer cells.
In diagnostics, there used to be a hard divide between radiology and pathology, where methods were largely considered incompatible with one another. However, to pave the way for next-generation diagnosis, Professor Regina Beets-Tan urged both sides to come out from their trenches and appreciate the synergies the fields have to offer. In her presentation at the European Congress of Radiology (ECR)…
Atrial fibrillation is the most common heart rhythm disorder globally. Patients at high risk for AF, such as those with heart failure or prior stroke, should be tested at every GP visit, experts say.
US oncologists are exploring a new combined chemotherapy and surgical approach to safely remove advanced pancreatic tumors that were previously considered inoperable.
A novel AI-based, non-invasive diagnostic tool enables accurate brain tumor diagnosis, outperforming current classification methods. The tool leverages MRI information to aid clinical decision making.
In a breakthrough for personalised oncology, scientists have developed and demonstrated a novel platform that can significantly reduce the time needed to determine the efficacy of anti-cancer drugs.
Most head and neck tumours are discovered in late due in part to the fact that there is no established method for early detection. To close this gap, a team at oncgnostics, a biotechnology company based in Jena, Germany, is participating in a study which aims to develop an early detection test.
Breast cancer has no “one size fits all” therapy approach: subtypes differ significantly in malignancy, progression, and treatment response. Therefore, the more is known about the type of carcinoma in a patient, the better the outcome. At the annual scientific EUSOBI meeting in Valencia, Dr Ramona Woitek pointed out the potential of novel imaging techniques and computational image analysis…
Researchers have unveiled a detailed understanding of immune responses in cancer, potentially paving the way for the development of new therapeutic strategies, the team hopes.
A newly-developed biosensor could be an alterative to MRI and mammography for breast cancer screening. The handheld device uses saliva on test strips to determine whether cancer is present.
Academic labs and biotech firms pioneer multi-cancer early detection with emerging technologies. Screening for multiple cancers with a simple blood or urinary draw could be a game-changer. Two research teams in particular have advanced the field.
Three disease subtypes, based on causes rather than symptoms: A new classification model for Parkinson's disease aims to pave the way for better diagnostics and therapies.
As a result from better living standards and medical advances, population longevity increases – a development which, paradoxically, current healthcare systems are ill-prepared for, Sir John Bell points out. The UK’s Our Future Health programme, which he chairs, exemplifies the paradigm shift to a prevention-centered healthcare approach.
The climate crisis and AI – arguably two of the most hotly-debated and relevant topics of our time – share an intricate relationship: While computation of complex AI routines commands an immense carbon footprint, it is these algorithms that might be the very key to mitigate the effects of global warming. In a dedicated session at ECR 2023, radiologists explored the societal and environmental…
A new US study suggests a new way to personalize mental health care: They found compounds in the blood of people with depression and suicidal ideation that could be detected using a blood test.
US researchers discuss three blood-based liquid biopsies, namely circulating tumor cells, circulating tumor DNA and tumor-derived exosomes, as they relate to prostate cancer management.
Researchers and clinicians at Washington University in St. Louis found a way to improve diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes.
Researchers from the University of Birmingham have designed and developed a novel diagnostic device to detect traumatic brain injury (TBI) by shining a safe laser into the eye.
Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe Covid-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a Covid-19 infection. This will allow physicians to adjust treatment at an early stage. The researchers used a method…
Ten times more detail than current 7T scanners, over 50 times more than 3T: A new type of functional MRI will allow neuroscientists to more precisely localize and trace brain networks.
Incidence of lung cancer among people who never smoked is rising. A new AI tool opens the door for opportunistic screening for this group, using existing chest X-rays in the electronic medical record.
A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.
Faster, more accurate and cost-effective testing: Experts outline the beginnings and evolution of “lab-on-a-chip” technology, and its benefits for advanced and next-gen operational platforms.
In a new study, researchers use a very large dataset to identify predictive brain imaging-based biomarkers of mental illness in adolescents.
In a new study, researchers from Fudan University have developed a novel urine-based prognostic model that promises to transform the management and treatment of bladder cancer.
A paper published in Trends in Cancer explains the advantages of RENACER, the world’s first repository of brain metastases live samples, created by researchers at CNIO.
MEDICA trade fair (Nov 13-16, Düsseldorf) is a major event for start-ups entering the health sector. Hundreds of young developers seek business contacts for cooperation concerning funding, production, approval, marketing or sales of their products.
Philips and Quibim have signed a multi-year agreement to work on an integrated solution including an AI-based software to automate real-time prostate gland segmentation in MR images.
University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth. This could lead to improved liver cancer treatment.
University of Oxford researchers demonstrated that neural cells can be 3D printed to mimic the architecture of the cerebral cortex. This could be used in patients after brain injuries.
A new imaging agent can predict early metabolic response to HER2-targeted treatment in metastatic breast cancer patients, according to new research published in the Journal of Nuclear Medicine.
Could a single biomarker detect all types of diseases related to dopamine deficiency in the brain? According to a Swedish research group, such a marker may have just been found.
Modern cancer therapies are tough on the tumours, but often, also on the heart of the patients. The “CARDIOCARE” project aims to reduce the cardiac burden of anti-cancer therapies through more patient-tailored treatment approaches. At the ESC cardiology congress, Professor Katerina Naka from the project’s consortium explained why older patients are at the highest risk of cardiotoxic…
Chemotherapy can be an effective means to fight breast cancer, but under certain circumstances, the treatment can cause dormant cancer cells to re-awaken, new research finds.
For the first time, researchers show that AI-based predictions can deliver comparable results to clinical tests on biopsies of patients with colorectal cancer (CRC).
Can per- and polyfluoroalkyl substances (PFAS) increase the risk of breast cancer? A new study by US researchers examines the effects of the so-called “forever chemicals”.
Osaka Metropolitan University scientists have developed an advanced AI model that utilizes chest radiographs to accurately estimate a patient’s "true" age.
A new analysis exploring the finances of bringing new cancer drugs to market has found that precision oncology drugs could be $1 billion cheaper to develop than non-precision drugs.
While screening programs for several of the commonest cancers are now well established, lung cancer screening has yet to reach anywhere near the same proportion of at-risk patients.
A new device that combines microfluidics on paper, electrochemical transduction and immunoassays on magnetic nanoparticles is useful for easy and rapid diagnosis of lung diseases.
The International Alzheimer's Congress (AAIC) in Amsterdam saw the presentation of new guidelines for diagnosing Alzheimer's disease - with blood biomarkers taking a central role.
Combining aerosol sampling and ultrasensitive biosensing, researchers have created a real-time monitor that can detect any of the Sars-CoV-2 virus variants in a room in about 5 minutes.
Researchers at Harvard Medical School developed a new tool that promises to improve the way pathologists see and evaluate a tumor by providing detailed clues about the cancer.
Chimeric antigen receptor (CAR) T-cell therapy is an immunotherapy treatment that re-engineers a patient’s own T-cells to help them attack malignant tumour cells. It has been very effective in the treatment of blood cancers, including certain types of leukaemia and lymphoma. However, two serious side effects are common as a result of the treatment: cytokine release syndrome (CRS) and immune…
Women suffering from multiple sclerosis temporarily get much better when pregnant. Researchers have now identified the beneficial changes naturally occurring during pregnancy.
New research suggests that combining blood biomarkers with genomic information more accurately, cost-effectively predicts the risk of developing diseases.
AI could find critical biomarkers that predict non-response to conventional treatment in patients with chronic myeloid leukaemia (CML) more quickly, researchers in Singapore find.
The accuracy of prostate-specific antigen (PSA) screening can be improved by including genetic factors that cause changes in PSA levels not associated with cancer, according to a multi-center study.
Damage to the brains of patients operated on for brain tumors may be assessed by measuring biomarkers in the blood pre- and postoperatively, a new study from the University of Gothenburg shows.
Researchers from the Organoid group (Hubrecht Institute) and UMC Utrecht have developed a biobank with organoids derived from patients with head and neck cancer (HNC).
Most AI techniques for rare disease diagnosis use anthropometric measurements of European origins, ignoring the genetic and morphological diversity of humans, a new study finds.
It is crucial that labs can rely on their slides for a seamless – and accurate – diagnosis. With many more commercial instruments focusing on flexibility and choice, these qualities are difficult to separate from subjectivity and complexity.
Autism spectrum disorder (ASD) is a developmental disorder associated with difficulties in interacting with others, repetitive behaviors, restricted interests and other symptoms that can impact academic or professional performance.
Genes are full of clues about a person's health and might also show the way for stroke recovery.
A new artificial intelligence model could bring much-needed clarity to doctors delivering prognoses and deciding on treatments for patients with colorectal cancer.
Researchers at the University of Campinas and the Federal University of São Carlos in Brazil have developed an electrochemical sensor that detects Parkinson's disease at different stages.
Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid.
A new clinical trial has shown that men diagnosed with prostate cancer can benefit from ‘radical radiotherapy’ that delivers treatment in five hospital visits instead of the typical 20.
A team of scientists has successfully generated genetically defined mouse models for two subtypes of multiple myeloma. This will contribute to a better understanding of how the disease develops in humans.
Carestream Health is funding and participating in an innovative pilot with OSIC that could lead to radiographs providing an early window into manifestations of IPF that are currently undetected.
A second-generation lab test for early detection of cervical cancer is the most recent addition to Oncgnostics’ portfolio. In particular, the company’s solution will help women in countries with limited cancer screening. Moreover, new research on the early detection of vulval and vaginal cancer might soon enable the development of tests for these cancers.
The distinction between primary tumors and metastases can be made quickly and accurately in brain tumors using radiomics and deep learning algorithms, a new study shows.
Canadian researchers are developing a new, ultra-sensitive biosensor to screen for Alzheimer’s disease and other diseases. The device has successfully completed the proof-of-concept stage.
Artificial intelligence (AI) may help improve care for patients who show up at the hospital with acute chest pain, according to a new study published in Radiology.
A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.
Identification of elderly persons at risk of developing cognitive impairment and dementia could be made possible by examining ergothioneine levels in the blood, researchers from Singapore find.
AI-based models for multimodality hybrid imaging have the potential to be a potent clinical tool but are currently held back by a lack of transparency and maturity, says Dr Irène Buvat, from the Laboratory of translational Imaging in Oncology, Institute Curie in Paris, France.
An international study shows that a new method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods.
Scientists from Singapore discovered a novel low-cost method of testing for cancers. The test sequences heated clinical samples to isolate cancer-specific signatures found in a patient’s blood.
In surgery, artificial intelligence (AI) is applied mostly in imaging, navigation, and robotic intervention. However, AI can also play a major role in preoperative planning. Objective decisions-making, optimal utilisation of operating theatres and less overtime are additional advantages that are achieved with the use of AI in surgery.
This summer, The European Commission launched I3lung, a new research initiative as a part of Horizon Europe, the EU’s research and innovation program. This research initiative aims to create a cutting-edge, decision-making tool to help clinicians and patients select the best lung cancer treatment based on each patient’s specific needs and circumstances.
At this year's Medica tradefair, laboratory medicine, medical technology and life sciences give new impulses to the entire healthcare market - especially in times of the corona pandemic. An overview.
White matter hyperintensities (WMH) on the brain seen on MRI represent a biomarker associated with a 50/50 risk of death within five years after a first incident acute ischemic stroke (AIS) or transient ischemic attack (TIA).
Imagine, one single standardising solution, enabling uncompromisingly fast results and providing you with the exact same predictable turnaround time.
With the rise of syndrome-style infections, co-infections and the current antimicrobial resistance challenges, the need for multiplexed diagnostics is now more important than ever.
