Alzheimer's

Alzheimer's disease is probably the best-known form of neurodegenerative disease, which is usually characterised by a progressive loss of cognitive, emotional and social abilities. But what actually happens in the brain? Read more about current research and therapeutic approaches to this form of dementia.

News • Dual role of tau phosphorylation

Surprising find: Alzheimer's biomarker found in newborn brains

What do the brains of newborns and patients with Alzheimer's disease have in common? Researchers have discovered a surprising shared trait - which might provide new insights into the disease.

News • New insights on CLEC5A

Immune gene discovery could prevent memory loss in Alzheimer's patients

A gene once believed to fight only viral infections could also hold the key to preventing memory loss in Alzheimer’s patients, a new study finds. This paves the way for new drug developments.

News • Hybrid imaging

PET/MR update for added value in theranostics

Bringing diagnostics and therapy closer together - that is the basic concept behind theranostics. Through further development of its PET/MR scanners, Siemens Healthineers aims to advance this…

News • Blood-based marker P-tau217

Simple, yet effective way to early detect Alzheimer's disease

A new, simpler and cheaper analytical method for the early detection of Alzheimer's disease could help bring blood tests into the healthcare system globally, according to a new study.

News • Nuclear imaging

PET radiotracer reveals inflammation in the brain

Using the COX-2 enzyme, a new PET imaging approach offers a never-before-seen view of inflammation in the brain, opening the door for clinical and research settings for various brain disorders.

Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers,…

Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently deployed to facilitate diagnosis, to monitor disease and effectiveness of treatments, to quantify progression, and to determine if a patient is appropriate for treatment or participation in a clinical…

News • Study explores impact

How brain trauma can trigger Alzheimer's disease

Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.

News • Exploring the neurovascular unit (NVU)

Promising new approach to detecting Alzheimer's

Research suggests a new approach to detecting Alzheimer’s disease: changes in brain oxygenation dynamics and neuronal function contribute to the neurodegeneration.

News • Role of the microbiome

Alzheimer's: X-rays unveil gut-brain connection

Researchers explore the connection between the gut and the brain and its impact on the onset of psychiatric and neurological disorders, including Alzheimer’s.

News • Promising imaging agents

Alzheimer's disease: New radiotracers for better detection

Two new radiotracers outperform the current FDA-approved tracer for detecting Alzheimer's disease, showing higher binding to affected tissue and greater selectivity for identifying tau tangles.

News • Potential for neurodegeneration

Head injuries may activate dormant viruses, trigger neurodegeneration, study finds

More than just a sports injury: A new study shows that head trauma may activate latent viruses, leading to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.

News • Surprising insights

Herpes infection might drive Alzheimer's, study suggests

Researchers uncovered a surprising link between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease.

News • Expanding brain imaging

Portable, low-field MRI shows promise for Alzheimer's diagnostics

A new study shows that a simplified, low-field MRI machine, augmented with machine learning tools, matches conventional MRI in measuring brain characteristics relevant to Alzheimer's disease.

News • Finding the fibrils

The “superspreaders” behind Alzheimer's disease

Misfolded proteins lead to Alzheimer's disease – but where do they come from? Using a particularly powerful imaging technique, Swiss researchers now uncovered a key mechanism.

News • From silent to destructive

Exploring the two phases of Alzheimer's disease

Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

News • Neurodegenerative diseases

Tauopathy or Alzheimer's? Biomarker and PET imaging for improved diagnosis

Researchers have identified biomarkers that, in conjunction with PET imaging, enable doctors to reliably distinguish between primary 4-repeat tauopathies and Alzheimer's disease.

News • Towards personalised risk assessment

Training an AI to early detect dementia with big data

With enough medical training data, AI can predict health conditions with astounding accuracy. Now, researchers want to use brain scans of the entire Scottish population to have an algorithm early detect dementia.

News • Promising diagnostic tool

Alzheimer's: New test to detect side effect risk from drugs

A novel test aims to predict whether Alzheimer’s patients are genetically predisposed to side effects from anti-amyloid drugs, a promising new class of Alzheimer’s therapeutics.

News • Improving Alzheimer’s disease imaging

Diagnostic sensors overcome blood-brain barrier

Researchers were able to package fluorescent sensors for passage across the blood-brain barrier (BBB) in mice. This holds promise to advance Alzheimer’s disease diagnosis and treatment.

News • Focus on Toxoplasma gondii

Could brain parasites help treat cognitive disorders?

Toxoplasma gondii is a parasite with the ability to infect the brain, causing life-threatening diseases. Researchers now want to harness its properties to advance treatment of cognitive disorders.

News • Public survey on medical conditions

Cancer seen as #1 health concern, AI as solution

Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.

News • What patients can expect

Alzheimer's: New method to predict cognitive decline

Researchers have developed a model to predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease. The next step is an app that uses this model.

News • Historia dementia

Did the ancient Greeks and Romans have Alzheimer’s?

Was dementia already an issue for Hippocrates and his contemporaries? A new analysis of classical Greek and Roman medical texts suggests that Alzheimer's is connected to modern environments.

News • National policies benchmark

Dementia care and treatment: Continuing inequalities across Europe

According to the European Dementia Monitor, there is still a clear East/West divide, with significant differences between countries in terms of availability, affordability, legal and human rights.

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