Alzheimer's

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News • Biomarker research

Alzheimer's: blood test detects beta-amyloid

Researchers from Japan have developed a method to detect build-up of amyloid β in the brain, a characteristic of Alzheimer’s disease, from biomarkers in blood samples.

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News • Ineffective coordination of services

Dementia care in the UK: Little has changed, study finds

A new study has found ineffective co-ordination of services and fragmented care plans in England has resulted in very little improving for dementia carers in forty years.

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News • Dementia destigmatisation

"This Is Us": Alzheimer's storyline in TV drama found to have positive impact

The inclusion of a narrative about Alzheimer’s disease in primetime TV drama “This Is Us” was found to help reduce stigma around dementia and motivate family discussions about plans for aging.

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News • In-depth view at neurodegeneration

New 3D imaging approach looks into earliest stages of Alzheimer's

Novel 3D imaging could comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important biomarker for the development of Alzheimer's disease.

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News • For the first time

Similarity between schizophrenia and dementia dicovered

Researchers for the first time compared schizophrenia and frontotemporal dementia, disorders that are both located in the frontal and temporal lobe regions of the brain.

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News • Early dementia detection

Protein sensor detects Alzheimer's up to 17 years in advance

A sensor identifies misfolded protein biomarkers in the blood. This offers a chance to detect Alzheimer's disease before any symptoms occur. Researchers intend to bring it to market maturity.

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News • Brain stimulation

Infrared light helmet might aid dementia patients

Researchers at Durham University are working on a new infrared light therapy that might have the potential to help people with dementia. In the approach, people wear a specially adapted helmet which delivers infrared light deep into the brain for six-minutes per treatment. This stimulates mitochondria that generate most of the chemical energy needed to power the biochemical reaction in the…

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News • microRNAs hint at cognitive decline

Researchers find warning signs for dementia in the blood

esearchers at the DZNE and the University Medical Center Göttingen (UMG) have identified molecules in the blood that can indicate impending dementia. Their findings, which are presented in the scientific journal “EMBO Molecular Medicine”, are based on human studies and laboratory experiments. Various university hospitals across Germany were also involved in the investigations.

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News • Dementia prevention

‘Blue spot’ in the brain helps detecting Alzheimer’s early

A miniscule area in the brain, known as the locus coeruleus (LC), or blue spot, can help to identify an increased risk of Alzheimer’s disease at a very early stage. The LC is hidden deep in the brainstem and can only be detected with advanced MRI equipment. Heidi Jacobs (Maastricht University/Harvard Medical School) used MRI scans to show that the tau protein can begin to spread in the LC three…

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News • Early diagnosis proteins

Study identifies 15 new biomarkers for pre­-dementia

A study by an international research group identified 15 novel biomarkers that are linked to late-onset dementias. These biomarkers are proteins, which predict cognitive decline and subsequent increased risk of dementia already 20 years before the disease onset. The proteins are related to immune system dysfunction, blood-brain-barrier dysfunction, vascular pathologies, and central insulin…

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News • Medication development platform

Smart biomarkers to find new drugs against brain diseases

Dr. Hayder Amin and Dr. Caghan Kizil from the DZNE’s Dresden site aim to speed up developing drugs against brain diseases through cutting-edge technology. To this end, they are generating an innovative technology platform, termed “i3D-Markers”, based on high-density microelectrode arrays and 3-dimensional networks of human neurons. Compounds to be tested will be dripped onto this setup, and…

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