Alzheimer's

Alzheimer's disease is probably the best-known form of neurodegenerative disease, which is usually characterised by a progressive loss of cognitive, emotional and social abilities. But what actually happens in the brain? Read more about current research and therapeutic approaches to this form of dementia.

News • Blood-based marker P-tau217

Simple, yet effective way to early detect Alzheimer's disease

A new, simpler and cheaper analytical method for the early detection of Alzheimer's disease could help bring blood tests into the healthcare system globally, according to a new study.

News • Nuclear imaging

PET radiotracer reveals inflammation in the brain

Using the COX-2 enzyme, a new PET imaging approach offers a never-before-seen view of inflammation in the brain, opening the door for clinical and research settings for various brain disorders.

Article • Detection of neurodegenerative condition

Developing blood biomarkers to diagnose Alzheimer’s disease

There is no known cure for Alzheimer’s disease (AD), although prescription drug-based treatments that can slow AD progression in some patients are starting to enter clinical use. Biomarkers,…

Article • Promising, but in need of further validation

Implementation challenges of blood biomarkers for Alzheimer’s disease

Blood-based biomarker (BBB) tests may represent the best weapon to combat the soaring rates of Alzheimer’s disease (AD) throughout the world. Existing clinically validated tests are currently…

News • Study explores impact

How brain trauma can trigger Alzheimer's disease

Traumatic brain injury (TBI) increases dementia risk, but the reasons are poorly understood. Now, a study explores the role of the brain's blood vessels as drivers of Alzheimer's disease.

News • Exploring the neurovascular unit (NVU)

Promising new approach to detecting Alzheimer's

Research suggests a new approach to detecting Alzheimer’s disease: changes in brain oxygenation dynamics and neuronal function contribute to the neurodegeneration.

News • Role of the microbiome

Alzheimer's: X-rays unveil gut-brain connection

Researchers explore the connection between the gut and the brain and its impact on the onset of psychiatric and neurological disorders, including Alzheimer’s.

News • Promising imaging agents

Alzheimer's disease: New radiotracers for better detection

Two new radiotracers outperform the current FDA-approved tracer for detecting Alzheimer's disease, showing higher binding to affected tissue and greater selectivity for identifying tau tangles.

News • Potential for neurodegeneration

Head injuries may activate dormant viruses, trigger neurodegeneration, study finds

More than just a sports injury: A new study shows that head trauma may activate latent viruses, leading to neurodegenerative conditions such as Alzheimer’s disease and Parkinson’s disease.

News • Surprising insights

Herpes infection might drive Alzheimer's, study suggests

Researchers uncovered a surprising link between Alzheimer’s disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease.

News • Expanding brain imaging

Portable, low-field MRI shows promise for Alzheimer's diagnostics

A new study shows that a simplified, low-field MRI machine, augmented with machine learning tools, matches conventional MRI in measuring brain characteristics relevant to Alzheimer's disease.

News • Finding the fibrils

The “superspreaders” behind Alzheimer's disease

Misfolded proteins lead to Alzheimer's disease – but where do they come from? Using a particularly powerful imaging technique, Swiss researchers now uncovered a key mechanism.

News • From silent to destructive

Exploring the two phases of Alzheimer's disease

Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institutes of Health (NIH) using sophisticated brain mapping tools.

News • Neurodegenerative diseases

Tauopathy or Alzheimer's? Biomarker and PET imaging for improved diagnosis

Researchers have identified biomarkers that, in conjunction with PET imaging, enable doctors to reliably distinguish between primary 4-repeat tauopathies and Alzheimer's disease.

News • Towards personalised risk assessment

Training an AI to early detect dementia with big data

With enough medical training data, AI can predict health conditions with astounding accuracy. Now, researchers want to use brain scans of the entire Scottish population to have an algorithm early detect dementia.

News • Promising diagnostic tool

Alzheimer's: New test to detect side effect risk from drugs

A novel test aims to predict whether Alzheimer’s patients are genetically predisposed to side effects from anti-amyloid drugs, a promising new class of Alzheimer’s therapeutics.

News • Improving Alzheimer’s disease imaging

Diagnostic sensors overcome blood-brain barrier

Researchers were able to package fluorescent sensors for passage across the blood-brain barrier (BBB) in mice. This holds promise to advance Alzheimer’s disease diagnosis and treatment.

News • Focus on Toxoplasma gondii

Could brain parasites help treat cognitive disorders?

Toxoplasma gondii is a parasite with the ability to infect the brain, causing life-threatening diseases. Researchers now want to harness its properties to advance treatment of cognitive disorders.

News • Public survey on medical conditions

Cancer seen as #1 health concern, AI as solution

Cancer, dementia, heart attack: these are the medical conditions people are most worried about, according to a new UK survey. It also reveals hopes for AI in the future of cancer research and care.

News • What patients can expect

Alzheimer's: New method to predict cognitive decline

Researchers have developed a model to predict cognitive decline in patients with mild cognitive impairment or mild dementia due to Alzheimer's disease. The next step is an app that uses this model.

News • Historia dementia

Did the ancient Greeks and Romans have Alzheimer’s?

Was dementia already an issue for Hippocrates and his contemporaries? A new analysis of classical Greek and Roman medical texts suggests that Alzheimer's is connected to modern environments.

News • National policies benchmark

Dementia care and treatment: Continuing inequalities across Europe

According to the European Dementia Monitor, there is still a clear East/West divide, with significant differences between countries in terms of availability, affordability, legal and human rights.

News • From the heart to the brain

Early onset of coronary heart disease increases dementia risk

Having coronary heart disease at a younger age was associated with an increased risk of dementia, Alzheimer’s disease and vascular dementia, a new study finds.

News • Lab model to find treatments for stroke, dementia

Finding (and fixing) vascular leaks in the brain

Using small blood vessels grown in the lab, researchers discover how vascular leaks leading to dementia and stroke emerge – and how this damage might be fixed.

News • Biosensor

Wireless, handheld device to detect Alzheimer’s and Parkinson’s biomarkers

A team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly.

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