Lung cancer

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HER2-targeted therapy

Promising results for therapy of non-small cell lung cancer

New data highlights a promising new treatment for individuals with HER2-mutant non-small cell lung cancer (NSCLC).

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Functional diagnostics

New assay could advance personalized cancer treatment

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or…

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Presented at HIMSS 21

New pathway for lung cancer added to AI-based clinical decision support software

Siemens Healthineers presents its second pathway for its AI-Pathway Companion at the Healthcare Information and Management Systems Society Global Health Conference 2021 (HIMSS 21). This new pathway…

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Controlling KRAS

New targeted gene therapy could stop lung cancer progression

A newly targeted therapy could help millions of lung cancer patients worldwide keep their cancers from spreading, says an expert at Cleveland Clinic, on the occasion of World Lung Cancer Day. Dr.…

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Oncology early detection tool

Blood test for 50+ types of cancer promising for screening

Final results from a study of a blood test that can detect more than 50 types of cancer have shown that it is accurate enough to be rolled out as a multi-cancer screening test among people at higher…

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Esophagitis

Lung cancer: Tailoring radiation therapy to reduce complications

For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment…

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Malignant Pleural Mesothelioma

AI to help fight asbestos-related cancer

International genomics research led by the University of Leicester has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes. Mesothelioma is caused by breathing asbestos particles and most commonly occurs in the linings of the lungs or abdomen. Currently, only seven per cent of people survive five years after diagnosis, with a prognosis…

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Updates: France, Germany, the UK, Croatia, Hungary, Poland, Russia

Pan-European lung cancer screening

Pan-European lung cancer screening is challenged due to the range of approaches in different countries. As attitudes towards smoking and smoking cessation programmes vary, experts are attempting to establish more unified lung cancer screening. The introduction of consistent pan-European lung cancer screening will be outlined at a special session during the online ECR 2021, with presentations…

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Expert prediction

How will Covid affect cancer death rates in 2021?

Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. In the latest predictions for cancer deaths in the EU and UK for 2021, published in the cancer journal Annals of Oncology, researchers led by Carlo La Vecchia (MD), a professor…

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Survival prediction

Deep learning may lead to better lung cancer treatments

Doctors and healthcare workers may one day use a machine learning model, called deep learning, to guide their treatment decisions for lung cancer patients, according to a team of Penn State Great Valley researchers. In a study, the researchers report that they developed a deep learning model that, in certain conditions, was more than 71% accurate in predicting survival expectancy of lung cancer…

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American Cancer Society

Breast cancer is the most commonly cancer worldwide

Cancer ranks as a leading cause of death in every country in the world, and, for the first time, female breast cancer is the most commonly diagnosed cancer, overtaking lung cancer, according to a collaborative report, Global Cancer Statistics 2020, from the American Cancer Society (ACS) and the International Agency for Research on Cancer (IARC). Data show that 1 in 5 men and women worldwide…

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Early detection

Blood-based methylation test offers promising data on lung cancer detection

In-vitro diagnostics company Universal Diagnostics (UDX) announced promising new data for its investigational blood-based lung cancer test. The data, presented at the IASLC 2020 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (#WCLC20), held virtually 28th-31st January 2021, used methylation status measurement of the tumour-derived portion from…

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Clinical decision support

AI deep learning of PET/CT images to support NSCLC treatment

A software tool to predict the most effective therapy for non-small cell lung cancer (NSCLC) developed by applying deep learning artificial intelligence (AI) to positron emission tomography/computed tomography (PET/CT) images has been developed by researchers at H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. The tool is designed to provide a noninvasive, accurate method to…

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The ‘new normal’ after Covid-19

Lung cancer screening: The slow return of mobile units

The coronavirus pandemic has had a severe impact on healthcare services but one area where that has been felt particularly deeply is with lung cancer screening. With sessions cancelled, treatment delays and social-distancing and safety requirements, many patients have been affected. However, as services begin to pick up again and lung cancer screening returns, three experts closely associated…

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Immunotherapy, iRecist and complications

Lung cancer imaging (in a post-Covid world)

The evolving area of immunotherapies in lung cancer and the role of iRecist treatment assessment protocols were investigated during a virtual session organised by the British Institute of Radiology (BIR). Consultant radiologist Dr Charlie Sayer, specialist in lung cancer imaging at the Brighton and Sussex University Hospitals Trust, South of England, focused on immunotherapies, the limitations of…

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Review highlight need

Lung cancer screening: experts appeal for wide implementation of LDCT

A new review, conducted by Professor John Field from the University of Liverpool and Professor Matthijs Oudkerk, University of Groningen, provides an authoritative insight into the current status of lung cancer screening. Lung cancer kills more people than any other cancer. The number of deaths in 2017 in the UK was 3,300, making lung cancer the commonest cause of cancer death in the UK for both…

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Prevention programs

Smoking women less likely to use cancer screening services

Smoking is strongly linked to lower use of cancer screening services by women, and more advanced disease once cancer is diagnosed, new research reveals. Tobacco use is falling in many parts of the world, but it’s falling less rapidly among women than it is among men. And lung cancer remains the leading cause of cancer death among women, say the researchers. The evidence also suggests that women…

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Cell invasion

Filopodia: The long 'fingers' of highly invasive lung cancer

Tiny finger-like projections called filopodia drive invasive behavior in a rare subset of lung cancer cells, researchers at Winship Cancer Institute of Emory University have found. Adam Marcus’ lab has developed innovative techniques for separating “leaders” and “followers,” subpopulations of tumor cells that cooperate during the process of metastasis. The lab’s new analysis of what…

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The difficulty? Unpredictability in the entire process

Immunotherapy for lung cancer patients

Better outcomes, more favourable prognoses – oncologists and their lung cancer patients didn’t dare to dream about it. Finally, there might be hope. The so-called checkpoint inhibitors (immunotherapy drug) have been used successfully, albeit not for every patient. They are a double-edged sword, with risks as well as opportunities, as explained by Professor Cornelia Schäfer-Prokop.

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Immune cell monitoring

AI could predict risk of lung cancer recurrence

Computer scientists working with pathologists have trained an artificial intelligence (AI) tool to determine which patients with lung cancer have a higher risk of their disease coming back after treatment. The AI tool was able to differentiate between immune cells and cancer cells, enabling researchers to build a detailed picture of how lung cancers evolve in response to the immune system in…

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New concept 'HeiMeKOM'

Involvement of patients and relatives improves cancer communication

The Heidelberg Thorax Clinic is trialling a newly structured, longitudinal communication concept to meet proactively the complex needs of stage IV lung cancer patients and their relatives. The concept is aimed at enhancing prognostic understanding and building the basis for proactive care planning, early integration of palliative care and shared decision-making, ultimately improving overall care.

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New sensor tech

A more reliable way to early detect lung tumours

People who are at high risk of developing lung cancer, such as heavy smokers, are routinely screened with computed tomography (CT), which can detect tumors in the lungs. However, this test has an extremely high rate of false positives, as it also picks up benign nodules in the lungs. Researchers at the Massachussetts Institute of Technology (MIT) have now developed a new approach to early…

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