The American Academy of Pediatrics has issued its first comprehensive guideline on the evaluation and treatment of children and adolescents with obesity, marking an end to previous recommendations.
Overweight increases the risk of an imbalance in sugar metabolism and even diabetes – but the opposite is also true: insulin production deficits contribute to overweight, a new study shows.
Development of effective live bacterial therapeutics may depend more on using and re-introducing native microbes that can stick around than how the microbes are modified.
Hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly.
When it comes to getting healthy and reducing mortality risk, increasing physical activity and improving fitness appear to be superior to weight loss.
A study of more than 18 million pregnancies has shown a strong and graded relationship between women’s heart health and pregnancy outcomes. The research is published in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). The researchers examined the presence of four risk factors for cardiovascular disease in women prior to pregnancy: unhealthy…
In a recent study by University of Alabama at Birmingham researchers, findings indicate that among patients with heart failure, obesity is associated with a higher risk of heart failure hospitalization or death due to cardiac causes. However, achieving biomarker-based treatment goals in heart failure improves the prognosis for patients irrespective of their obesity status.
Imagers need special scenarios, skills and tools to examine larger patients, who present more challenges when it comes to radiological procedures. New ultrasound devices could help reduce dose exposure in these patients, who are more likely to undergo x-ray based examinations and receive a higher dose during those, experts explained in a dedicated session during ECR 2020.
Age, male sex, obesity, and underlying illness have emerged as risk factors for severe and fatal cases of COVID-19 in the UK, according to the largest cohort study to date published by The BMJ. As the largest prospective observational study reported worldwide to date, it provides a comprehensive picture of the characteristics of patients hospitalised in the UK with COVID-19 and their outcomes.…
Eric Prossnitz, PhD, from the University of New Mexico Health Services and his team hope to help 93 million obese Americans fight their fat. In a paper published in Science Translational Medicine, they reported that G-1, a cancer-fighting compound they discovered some years ago, reduces fat in obese mice. Although G-1 is currently in phase 1 clinical trials for cancer, Prossnitz and his team are…
In their quest to find new and better methods to make cancer cells more susceptible to treatment, Karin Lindkvist and her research group at Lund University in Sweden are looking into the world of molecules, using the X-rays at the MAX IV laboratory. The researchers believe that limiting the cells' access to sugar will make cancer cells more sensitive to treatment. Many of the cancer treatments…
Diseases such as cardiovascular diseases, cancer or certain lung diseases are among the most common non-natural causes of death today and account for about 70 percent of deaths worldwide. They are defined by the World Health Organization (WHO) as non-communicable because they are assumed to be caused by a combination of genetic, lifestyle and environmental factors and cannot be transmitted…
The World Health Organization has estimated more than 340 million children and adolescents ages 5-19 are overweight or obese, and the epidemic has been linked to more deaths worldwide than those caused by being underweight. The Centers for Disease Control recently reported an estimated 1 in 5 children in the United States, ages 12-18, are living with prediabetes — increasing their risk of…
In animals, a vaccine modifying the composition and function of the gut microbiota provides protection against the onset of chronic inflammatory bowel diseases and certain metabolic disorders, such as diabetes and obesity. This research was conducted by the team of Benoît Chassaing, Inserm researcher at Institut Cochin (Inserm/CNRS/Université de Paris), whose initial findings have been…
Women who have C-sections are no more likely to have children who develop obesity than women who give birth naturally, according to a large study by researchers at Karolinska Institutet in Sweden published in the journal PLOS Medicine. The findings contradict several smaller studies that did find an association between C-section deliveries and offspring obesity but did not consider the numerous…
Obesity not only means someone is overweight but, over time, they will probably suffer sequelae that increasingly impair quality of life and are potentially fatal – these include hypertension, coronary heart disease, type two diabetes, pulmonary function disorders, tumours, plus an increased risk during surgery and anaesthesia. In patients with morbid obesity, class three obesity, according to…
Areas with a higher number of fast food restaurants have more heart attacks, according to research presented at the 67th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand (CSANZ). The study also found that for every additional fast food outlet, there were four additional heart attacks per 100,000 people each year. Study author Tarunpreet Saluja of the University of…
The traditional classification of diabetes, mainly in type 1 and type 2 diabetes, has been challenged by studies from Scandinavia. In the current issue of The Lancet Diabetes & Endocrinology, researchers from DDZ together with colleagues from DZD and University of Lund published a cluster analysis of diabetes allowing for phenotyping into subgroups, which extended the findings by showing that…
A new study harnessed the unique genetic history of the people of Finland to identify variations in DNA that might predispose certain individuals to disease, whether or not they are Finnish themselves.
