Search for: "simulation" - 250 articles found

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Article • Future treaments discussed at senology congress

How will we treat breast cancer in 2034?

The year: 2034. Breast cancer patients benefit from perfectly personalised diagnostics and therapies. The tedium of follow-up treatments is a thing of the past, thanks to AI, augmented reality and robotics. Just a tale from the realm of science fiction, or could this soon be clinical reality? At the annual meeting of the German Senologic Society, Prof Dr Marc Thill from the Agaplesion Markus…

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Testing Devices

mamTOMO Digital Breast Tomosynthesis Phantom

HighlightsThe mamTOMO phantom is a novel approach in DBT QA. The phantom incorporates 3D test objects that simulate lesions and nonspiculated masses in a nonhomogeneous background.An associated automated evaluation software assists at all test stages from image processing, statistic data evaluation to extrapolation of threshold diameters for lesion perceptibility.

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Business Intelligence

EasyDoseQM

HighlightsEasyDoseQM supports multi-site installations as well as the integration of measuring stations and column scales. Mobile digital radiography systems can be integrated and physically located with RFID technology. All supplied information can be analyzed with an integrated business intelligence tool. EasyDoseQM also includes a module to simulate organ dose with the help of a GPU based…

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News • Autonomous Sensory Meridian Response

ASMR videos: Why do they work?

Soothing words, gentle sounds: ASMR videos are known to induce pleasant tingling sensations in viewers. Researchers have now published the first systematic review on why (and how) this works.

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Sponsored • Digital solutions for radiology

How to accelerate healthcare innovation in AI

Tapping the thriving Radiology AI ecosystem, Bayer recently announced three collaboration agreements for its digital platform, Calantic Digital Solutions, as well as an AI accelerator program.

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Article • Extended reality

The application of XR in mental health care

Mental disorders are among the leading causes of ill-health and disability worldwide, and the demand for a viable solution to battle the mental health crisis has risen. The past two decades have witnessed the emergence of extended reality (XR) as a tool for investigation, assessment, and management in mental healthcare.

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Article • Game elements

Gamification in diabetes care

The number of gamified mobile applications is rising rapidly—especially in healthcare. Gamified apps or devices are used in many fields, from mental health therapy to stroke rehab to managing metabolic conditions. This article illustrates how gamification is employed in diabetes care.

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Article • Augmented reality in the OR

AR helps surgeons to see, feel and understand

X-ray vision, context-sensitive guidance, coordinator, training assistant and more: augmented reality (AR) has hit the OR. While still in its infancy AR does grow rapidly and has already shown enormous potential. University Professor Dr Rüdiger von Eisenhart-Rothe, Chair of Orthopaedics and Sports Orthopaedics at the Technical University Munich, explains the advantages of different AR…

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Article • Pre-, post- and interoperative

Wearable devices in the surgical environment

Wearable technology has become an important part of medicine, from tracking vital signs to disease diagnosis. In surgery, wearable technologies can now assist, augment, and provide a means of patient assessment before, during and after surgical procedures. Wearable technologies are applied before the patient even reaches the operating room, for example in prehabilitation, i.e. pre-treatment…

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Sponsored • Trade fair presence

A myriad of French innovations at Medica 2021

This year as every year, the very best in global HealthTech will be converging on Dusseldorf for the Medica trade fair. With more than 127 companies attending the event from November 15-18, France will have one of the largest contingents there. Grouped together under the brand umbrella of “French Healthcare”, the French MedTech companies will be presenting their many innovations to industry…

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Article • Extended realities in the OR

‘XR is fusing surgical reality with medical images’

Leading medical XR experts gathered at Shift Medical to discuss developments on the use of immersive technologies in medicine. We interviewed Doctor Egidijus Pelanis of Oslo University Hospital, about applying extended realities in the operating room.

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News • Incubator 2.0

Artificial uterus improves odds for preemies

“An artificial uterus – the incubator 2.0 – will become a reality within 10 years,” says Jasmijn Kok, one of the founders of Juno, a spin-off from the Eindhoven University of Technology, Netherlands. Together with researchers from the department of Industrial Design from the University, including her twin sister Lyla Kok, she wants to bring a technology that increases the chances of…

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News • Additional costs that pay off

For women with dense breasts, MRIs are cost effective for detecting breast cancer

New research indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography. About 10% of women have extremely dense breasts, and current mammography screening guidelines do not recommend additional imaging tests unless there is a strong family history or genetic risk for breast cancer. Such women face two problems. They have increased…

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Article • Orthopaedic advances

Virtual training by hip implant simulator

Trainee trauma or orthopaedic surgeons have limited chances to practice hip replacement surgery before their first hands-on case. To change this, a team in the Dynamic HIPS project aim to improve this by creating a dynamic hip replacement simulator for future surgeons to practice the intervention and develop a reality-based feel for the procedure.

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News • Biological image analysis

Machine learning accelerates super-resolution microscopy

Scientists use super-resolution microscopy to study previously undiscovered cellular worlds, revealing nanometer-scale details inside cells. This method revolutionized light microscopy and earned its inventors the 2014 Nobel Prize in Chemistry. In an international collaboration, AI researchers from Tübingen have now developed an algorithm that significantly accelerates this technology.

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News • Brain cancer research

Researchers 3D-print entire active tumor

Researchers at Tel Aviv University have 3D-printed a first-of-its-kind glioblastoma tumor that mimics a living cancer malignancy, powering new methods to improve treatment and accelerate the development of new drugs for the most lethal type of brain cancer. Glioblastoma is notoriously fatal as it accounts for the majority of brain tumors and is highly aggressive. The average survival time of…

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News • Increased processing power

Personalizing cancer treatment with quantum computing

Cancer patients’ medical records can often comprise up to 100 terabytes of individual — and usually very heterogeneous — data, including blood and tumor values, personal indicators, sequencing and treatment data, and much more besides. Up to now, it has been virtually impossible to use this wealth of information efficiently due to a lack of appropriate processing mechanisms. As a result,…

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News • Cell delivery vehicles

Bio-inspired nanocontainers could enter cells and release their medical cargo

Nanocontainers can transport substances into cells where they can then take effect. This is the method used in, for example, the mRNA vaccines currently being employed against Covid-19 as well as certain cancer drugs. In research, similar transporters can also be used to deliver labelled substances into cells in order to study basic cellular functions. To take advantage of their full potential,…

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News • Tool to identify tumour mutations

Machine learning fuels personalised cancer medicine

The Biomedical Genomics laboratory at the Institute for Research in Biomedicine (IRB) Barcelona has developed a computational tool that identifies cancer driver mutations for each tumour type. This and other developments produced by the same lab seek to accelerate cancer research and provide tools to help oncologists choose the best treatment for each patient. The study has been published in the…

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News • Immersive technologies

Improving VR use in healthcare education

A new report that could help improve how immersive technologies such as Virtual Reality (VR) and Augmented Reality (AR) are used in healthcare education and training has been published with significant input from the University of Huddersfield. Professor David Peebles, Director of the University’s Centre for Cognition and Neuroscience, and Huddersfield PhD graduate Matthew Pears contributed to…

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News • Promising research tool

World's first digital cancer cell model

Computer models have been standard tools in basic biomedical research for many years. However, around 70 years after the first publication of an ion current model of a nerve cell by Hodgkin & Huxley in 1952, researchers at Graz University of Technology (TU Graz), in collaboration with the Medical University of Graz and the Memorial Sloan Kettering Cancer Center in New York, have finally…

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News • Analysis of 2nd and 3rd Corona wave

Rapid tests effectively contain Covid-19

Rapid tests effectively broke Covid-19 infection chains in spring 2021. This is shown by a model developed by researchers of the ECONtribute: Markets & Public Policy Cluster of Excellence of the Universities of Bonn and Cologne, the Collaborative Research Center Transregio 224 EPoS of the Universities of Bonn and Mannheim, and the Institute for the Study of Labor (IZA). According to the…

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News • Virtual reality experiment

Using VR to promote Covid-19 vaccination

234 random passersby got the opportunity to try a new virtual reality game, when researchers from the University of Copenhagen visited Fælledparken to test the efficiency of VR technology within health information. During the event, the participants tried their strength against a new VR game that simulates the effect of herd immunity. The game is developed by researchers at the Virtual Learning…

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News • Digital patients, promising results

Are 'virtual' trials the future of research?

A study involving virtual rather than real patients was as effective in evaluating a medical device used  to treat brain aneurysms, according to new research. The findings are proof of concept for what are called in-silico trials, where instead of recruiting people to a real-life clinical trial, researchers build digital simulations of patient groups, loosely akin to the way virtual…

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News • Unexpected find

Anti-tapeworm drug shows promise against Covid-19

Researchers from the German Center for Infection Research (DZIF) at Charité – Universitätsmedizin Berlin and the University of Bonn have examined the way in which SARS-CoV-2 reprograms the metabolism of the host cell in order to gain an overall advantage. According to their report in Nature Communications, the researchers were able to identify four substances which inhibit SARS-CoV-2…

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News • Severe effects

How COVID-19 wreaks havoc on human lungs

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have published the first detailed atomic-level model of the SARS-CoV-2 "envelope" protein bound to a human protein essential for maintaining the lining of the lungs.

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News • Neuroscience

A deep dive into the brain

Researchers from ETH Zurich and University of Zurich have developed a new microscopy technique that lights up the brain with high resolution imagery. This allows neuroscientists to study brain functions and ailments more closely and non-​invasively.

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News • Public health strategy

Covid-19: Delay in second vaccine dose may prevent deaths under certain conditions

Delaying the second dose of Covid-19 vaccines, at least for people aged under 65, could result in up to 20% lower mortality, but only under certain conditions, finds a US study published by The BMJ. These conditions include a one dose vaccine effectiveness (efficacy) of 80% or higher and vaccination rates of 0.1% to 0.3% of the population per day. If these conditions apply, the researchers say…

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News • Robotic navigation

Helping robots find their way in crowded emergency rooms

Computer scientists at the University of California San Diego have developed a more accurate navigation system that will allow robots to better negotiate busy clinical environments in general and emergency departments more specifically. The researchers have also developed a dataset of open source videos to help train robotic navigation systems in the future. The team, led by Professor Laurel Riek…

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News • Vigorous ventilation

Covid-19: Why faster air exchange in buildings is not always beneficial

Vigorous and rapid air exchanges might not always be a good thing when it comes to addressing levels of coronavirus particles in a multiroom building, according to a new modeling study. The study suggests that, in a multiroom building, rapid air exchanges can spread the virus rapidly from the source room into other rooms at high concentrations. Particle levels spike in adjacent rooms within 30…

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News • M.O. of Darobactin unveiled

Novel antibiotic deceives bacteria through mimicry

An increasing number of bacterial pathogens are resistant to antibiotics. And the most dangerous pathogens share a common feature: a double membrane that is difficult to penetrate. Even when antibiotic agents are able to break into this shell, the bacteria just pump them right out again. But a recently discovered compound called Darobactin manages to circumvent these protective measures and kill…

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News • Bioengineering

Producing transplantable livers in the laboratory

Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory. The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of…

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Interview • Interventional Radiology

Endovascular simulator – your coach for complex interventions

With interventional procedures becoming more and more complex the demands on the interventionalists are also increasing. Endovascular simulators allow practical angiography training. In December 2020, the University Hospital Essen, Germany, was the first European facility to install Mentice’s VIST G7+. Professor Dr Jens Theysohn, senior physician at the Institute of Diagnostic and…

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News • A much-needed update

New 'double antibody' delivers dual strike SARS-CoV-2 and its variants

The Institute for Research in Biomedicine (IRB) in Switzerland developed a second-generation ‘double antibody’ that protects from SARS-CoV-2, the virus causing Covid-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy. Antibody-based immunotherapy was already shown to be effective against Covid-19 but faces two main obstacles: it needs to work…

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News • Delay in treatment for serious illness

Digital Covid-19 'symptom checkers' may do more harm than good

Digital Covid-19 ‘symptom checkers’ may stop some patients from getting prompt treatment for serious illness, suggests an international case simulation study. Both the US and UK symptom checkers consistently failed to identify the symptoms of severe Covid-19, bacterial pneumonia, and sepsis, frequently advising these cases to stay home, the findings indicate. The availability and use of…

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News • Collagen 'pushing'

Supercomputer illustrates mechanical process of cancer growth

According to the World Health Organization, one in six worldwide deaths have been attributed to cancer; however, these fatalities were not due to initial malignant tumors—the deaths were caused by the spread of cancer cells to surrounding tissues and subsequent tumor growth. These tissues, which consist largely of collagen, have been the focus of a recent collaborative study by a team from…

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News • Pandemic forecast modelling

Exploring the uncertainties in Covid-19 simulations

Computer modelling to forecast Covid-19 mortality contains significant uncertainty in its predictions, according to an international study led by researchers at University College London (UCL) and Centrum Wiskunde & Informatica (CWI) in the Netherlands. Their article ‘The Impact of Uncertainty on Predictions of the CovidSim Epidemiological Code’ was published in Nature Computational…

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News • Longer lasting implants for younger people

Engineering more durable artificial joints

A £4 million research project will develop a new generation of artificial joints that last longer, produce fewer side effects and are better suited for younger people. The international collaboration, led by the University of Leeds and funded by the EU’s Horizon 2020 programme, will focus on improved design and testing to reduce the chance that the implants develop faults and fail, or cause…

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News • Alternative therapies

Artificial aorta can reduce patients' blood pressure

Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an ongoing need for alternative therapies. With new developments in cardiac assistance systems, we can delay the need for a transplant – or even eliminate it altogether,” says Professor Yves Perriard, head of EPFL’s…

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News • Promising alternative to heart transplants

'Artificial aorta' to reduce blood pressure

Engineers at EPFL’s Center for Artificial Muscles have developed a silicone aorta that can reduce how hard patients’ hearts have to pump. Their breakthrough could offer a promising alternative to heart transplants. “Over 23 million people around the world suffer from heart failure. The disease is usually treated with a transplant, but because donated hearts are hard to come by, there is an…

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News • Promising agents

The effect of vitamins, steroids and potential antivirals on SARS-CoV-2

Evidence is emerging that vitamin D – and possibly vitamins K and A – might help combat Covid-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they – and other antiviral drugs – might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so…

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Interview • IT analysis and study

Optimising OR procedures in orthopaedic surgery

Could surgical procedures for hip or knee arthritis be improved? IT specialists at Leipzig University Hospital’s Innovation Center for Computer-Assisted Surgery (ICCAS), and physicians in the Department of Orthopaedic, Trauma and Plastic Surgery department, analysed and optimised the operating room (OR) setup, legwork and instruments handling. We asked project manager Juliane Neumann, at…

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News • Aneurysm operations

4D simulation increases safety in brain surgery

Aneurysm operations in the brain rank among the most delicate procedures in neurosurgery. The highest demands are placed on surgeons when choosing the type of intervention, planning the route and carrying out extremely delicate procedures on the blood vessel. A new training technology co-developed between Inselspital, Bern University Hospital, and ARTORG Center of the University of Bern, will…

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News • Alternative to traditional surgery

Focused ultrasound shows promise for Parkinson’s treatment

A scalpel-free alternative to brain surgery has the potential to benefit people with Parkinson’s disease symptoms that are much more severe on one side of the body, new research suggests. More testing is needed, but the approach, which uses a technology called focused ultrasound, could offer a new option for patients whose symptoms are poorly controlled by medications and those who cannot or do…

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News • Simulated system

New AI approach to find treatments for brain disorders

Getting computers to “think” like humans is the holy grail of artificial intelligence, but human brains turn out to be tough acts to follow. The human brain is a master of applying previously learned knowledge to new situations and constantly refining what’s been learned. This ability to be adaptive has been hard to replicate in machines. Now, researchers at the Salk Institute have used a…

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Sponsored • In-vitro diagnostics

Join Mindray at 2020 AACC Virtual Event

The 2020 AACC Annual Scientific Meeting & Clinical Lab Expo is just around the corner, and this year, we are going virtual! At Mindray, we are dedicated to empowering TRUST through technology, innovation, and commitment to the advances of science in the in-vitro diagnostics field. Join our virtual community now, and explore Mindray’s reliable solutions trusted by laboratories worldwide. You…

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News • Fractional exponents

New approach for more accurate epidemic modeling

A new class of epidemiological models based on alternative thinking about how contagions propagate, particularly in the early phases of a pandemic, provide a blueprint for more accurate epidemic modeling and improved disease spread predictions and responses, according to a study published recently in Scientific Reports by researchers at the University of California, Irvine and other institutions.

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Article • Assessing potential values

5G: The impact of wireless technology in healthcare

In a virtual roundtable 5G discussion five healthcare IT experts, three senior executives from major USA medical centres and two consultants, discussed questions posed by members of the Healthcare Information and Management Systems Society (HIMSS).

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Article • Resecting brain tumours

Benefits of ultrasound in neurosurgical oncology

Italian neurosurgeon Professor Francesco Di Meco, explored the current and potential role of intra-operative ultrasound in neurosurgical oncology during the annual meeting of the European Association of Neurosurgical Societies (EANS) this October. The extent of resection is considered a prognostic factor in operative neuro oncology surgery and image-guided surgery is being regarded as one of the…

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News • Improving imaging

Light up diseases with 'photonic lanterns'

Researchers at Heriot-Watt University have developed a new technique that will allow medical professionals to see disease deep inside the human body in 10 times more detail. Professor Robert Thomson and his team want to improve endoscopies, when long, thin optical fibres are used to look inside the body. The new technique will open up a route to unprecedented imaging resolution, says Thomson, and…

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Article • Creating instruments, implants & more onsite

Reforming surgical procedures with 3D printing hubs in hospitals

Increasingly, hospitals use 3D printing in surgery because the technology can enable fast, unique production of patient-tailored tools at relatively low costs. ‘As the technology itself is developing and accelerating at a fast pace, hospitals may be left behind if they choose not to adopt these advances,’ said Limor Haviv, surgical 3D printing designer at 3D4OP. Today, 3D printing is used in…

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News • Risk assessment

Understanding the spread of COVID-19 on public transport

Researchers at Newcastle University are involved in a study to understand the risks of COVID-19 transmission on public transport and to identify the best measures to control it. Known as Project TRACK (Transport Risk Assessment for Covid Knowledge), the study will conduct fieldwork on buses and trains in London, Leeds and Newcastle, including the Metro system in Tyne and Wear.

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News • Simulation model for pathological mechanisms

Understanding the progress of viral infections

It is only 120 millionths of a millimetre in size but can bring entire countries to a standstill: the Corona virus. Even if it were to disappear one day, viral infections will still be among the most frequent and difficult-to-treat diseases in humans. Even decades of research have only produced a few standardized vaccines and strategies for treatment to combat just a small number of viruses. Nor…

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News • Gathering sonography experience

Partnership to provide ultrasound online interactive training

Royal Philips and LeQuest, a provider of online interactive simulation-based training for the use of medical devices, announced a partnership to provide online interactive training for the Philips Ultrasound Affiniti system. As a result, medical staff can train individually at their own convenience without the need for equipment, avoiding the resulting loss of operational time on the system, as…

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Article • Video consultation on the rise

“A patient’s home has to become a mobile diagnostic centre”

There are many reasons why for some patients a visit to the doctor’s office is difficult or well-nigh impossible – limited mobility after surgery, old age, or a handicap. For others, particularly in rural areas, the doctor is often far away and/or difficult to reach due to poor public transport. In times of corona, another important issue emerged: infection protection.

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Article • Rapidly meeting a surging demand

The science behind 3-D printed nasal swabs

Medical device approved 3-D printers are producing clinically safe and effective nasopharyngeal swabs for COVID-19 testing. A nasal swab may seem rudimentary, but is essential for testing COVID-19. Diagnostic test kits and components – nasal swabs, collection vials, and chemical reagents – have been in short supply worldwide, especially in March. Ironically, nasopharyngeal swabs are…

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Article • Sterilising with VHP, EO or HPGP

Sterilisation study puts cleansing methods to the test

A new study from the USA highlights how low temperature sterilisation can jeopardise effective cleansing of medical tools and lead to transmission of dangerous bacteria to patients. Steam sterilisation was shown to be the most effective and robust sterilisation technology. However, the researchers, working at the University of North Carolina, also showed that vaporised hydrogen peroxide (VHP)…

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News • Electrostatic interactions

New research exposes weak spot in SARS-CoV-2

Northwestern University researchers have uncovered a new vulnerability in the novel coronavirus’ infamous spike protein — illuminating a relatively simple, potential treatment pathway. The spike protein contains the virus’ binding site, which adheres to host cells and enables the virus to enter and infect the body. Using nanometer-level simulations, the researchers discovered a positively…

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News • Researchers use supercomputer

New insights into hepatitis B

Researchers at the University of Delaware, using supercomputing resources and collaborating with scientists at Indiana University, have gained new understanding of the virus that causes hepatitis B and the "spiky ball" that encloses the virus's genetic blueprint.

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News • Droplet spread simulation

Mathematical model to predict the spread of airborne diseases

A new mathematical model is helping develop the current understanding of how airborne diseases such as COVID-19 can spread during breathing and aerosol generating procedures. Researchers from Heriot-Watt University and the University of Edinburgh have developed a mathematical model of droplet migration. Dr Cathal Cummins of Heriot-Watt’s School of Mathematical and Computer Sciences and…

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Video • Improving first aid

New 3D CT scanning method shows what happens during CPR

Rapid first aid during cardiac arrest makes the difference between life and death. But what happens to the heart and the internal organs when people come running and begin to give well-meaning but heavy-handed heart massage as they attempt to keep the person who has suffered a cardiac arrest alive? A research collaboration between the Department of Forensic Medicine at Aarhus University and the…

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News • Nanoparticles

Luminescent substance allows accurate viewing of body parts

Researchers have designed a fluid that works like a luminous ink to obtain very sharp images of damaged tissues, organs and cartilages in diagnostic tests. This new compound, still in the laboratory phase, reduces adverse effects on the human body because it allows lower amounts to be injected and the dose to be targeted only at the affected area.

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News • 3D microprinted scope

World’s smallest imaging device focuses on heart disease

A team of researchers led by the University of Adelaide and University of Stuttgart has used 3D micro-printing to develop the world’s smallest, flexible scope for looking inside blood vessels. The camera-like imaging device can be inserted into blood vessels to provide high quality 3D images to help scientists better understand the causes of heart attack and heart disease progression, and could…

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Video • COVID-19 video

Coughing visualization shows benefits of wearing a good mask

Coupling function with fashion, cloth and home-sewn face masks are available in a variety of forms and fabrics. While experts underscore that wearing a mask is effective in helping to prevent the spread of COVID-19, not all masks — or the materials with which they’re made — contain virus particles equally. In a new video, University of Wisconsin–Madison engineer Scott Sanders demonstrates…

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News • Coronavirus protection

COVID-19: The best (and worst) materials for masks

It's intuitive and scientifically shown that wearing a face covering can help reduce the spread of the novel coronavirus that causes COVID-19. But not all masks are created equal, according to new University of Arizona-led research. Amanda Wilson, an environmental health sciences doctoral candidate in the Department of Community, Environment and Policy in the Mel and Enid Zuckerman College of…

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Interview • Abbott cardiovascular

An increasingly dynamic cardiovascular presence

In the world of laboratory diagnostics, ‘Abbott’ is a household name. Few people however are aware of the fact that the company, headquartered in Illinois, USA, is also leading in other fields. A number of innovations in cardiac and vascular diagnostics and therapy might soon put Abbott in the limelight. Dr Angela Germer, Regional Director DACH, and Volker Keller, Head of Marketing DACH,…

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News • high-density EEG

A deeper look inside the brain

Understanding the source and network of signals as the brain functions is a central goal of brain research. Now, Carnegie Mellon engineers have created a system for high-density EEG imaging of the origin and path of normal and abnormal brain signals.

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News • Organic lungs, synthetic muscles

Biohybrid model re-creates respiration mechanics

Benchtop tools for studying the respiratory system misrepresent the interdependence between the diaphragm, abdomen and lungs. Meanwhile, computational models often hide the mechanisms in a black box computation, without a clear picture of what transpires in the process. This means students form a poor understanding of respiratory mechanisms and makes it hard to train clinicians for real scenarios…

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News • Bone cement research

Developing self-healing bone replacements

Our body is able to treat many injuries and wounds all by itself. Self-healing powers repair skin abrasions and enable bones to grow back together. However, doctors often have to lend a helping hand to repair bones after a fracture or due to a defect. Increasingly, bone replacement materials are being used, which partially or completely restore the form and function of the bone at the site of the…

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News • Robotic innovation

Micro robot rolls deep into the body

A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell travelling through the circulatory system. It has the shape, the size and the moving capabilities of leukocytes and could perhaps be well on its way – in a rolling motion of course – to revolutionize the minimally invasive treatment of…

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News • Better tissue discrimination, lower radioation dose

Improving image quality of CT scans

Computed tomography (CT) is one of the most effective medical tests for analysing the effects of many illnesses, including COVID-19, on the lungs. An international team led by the Universitat Oberta de Catalunya (UOC) has developed a new method that improves the quality of the images obtained from CT scans. The algorithm, which has been tested on simulated data, enables them to distinguish…

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News • COVID-19 contact tracing

NHS corona app can be a success (if it's linked to testing)

It is possible to implement a privacy-respecting contact tracing app that can achieve widespread adoption in the UK, but only if the NHS, rather than the government, run it, researchers at Cass Business School have found. The researchers found that adoption rates increase further if the app is linked to priority testing for COVID-19 for those who get infection alerts. They also found that the…

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Video • Coronavirus structured reporting

Radiology and COVID-19: How to establish safe workflows

Radiology experts from Norway and Germany highlighted the role of structured reporting in communicating clear results to the rest of the team, to improve patient and staff safety during the pandemic. They also related Germany’s experience of the crisis and what lies ahead in an online conference organized by the European Society of Radiology (ESR) last week.

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Article • Orthopaedics

VR training to improve hip replacement surgery

More than 200,000 patients undergo hip replacement surgery in Germany each year. To avoid complications and extend the lifespan of the artificial joint, the implants must be fitted precisely in the acetabulum (hip socket). The procedure, particularly milling the acetabulum, is not only difficult but also the technique is difficult to teach and train.

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News • Glioblastoma

New imaging technique to study 3D printed brain tumors

Glioblastomas are complex, fast-growing malignant brain tumors that are made up of various types of cells. Even with aggressive treatment — which often includes surgery, radiation, and chemotherapy — glioblastomas are difficult to treat, leading to an average survival of 11-15 months. In research published in Science Advances, Xavier Intes, a professor of biomedical engineering at Rensselaer,…

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News • Altered chromosomes

Breast cancer: targeted therapy can lead to treatment resistance

If chromosomes are unevenly distributed or otherwise altered during cell division, this normally damages the daughter cells and impairs their viability. Not in cancer cells, however, in which chromosome instability can actually confer a growth advantage under certain circumstances. Moreover, as scientists from the German Cancer Research Center have now demonstrated in mice, changes in the…

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News • New curriculum against exploitation

Teaching medical students to identify human trafficking victims

Human trafficking is a growing international public health concern. An estimated 400,000 people in the U.S. are affected, with as many as 88% of victims having seen a health care professional while they were being trafficked. As human trafficking evolves as a health concern, medical schools are starting to include the topic in education. However, it’s still in the early stages, says a Mayo…

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News • DeepMind to help human radiologists

Google-powered AI spots breast cancer

A computer algorithm has been shown to be as effective as human radiologists in spotting breast cancer from x-ray images. The international team behind the study, which includes researchers from Google Health, DeepMind, Imperial College London, the NHS and Northwestern University in the US, designed and trained an artificial intelligence (AI) model on mammography images from almost 29,000 women.…

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Article • TAITRA at Medica 2019

A vision of Taiwan innovation

A popular proverb in Mandarin goes ‘Hearing something a hundred times is not as good as seeing it once’ (百聞不如一見). Visiting the Taiwan pavilion at this year’s Medica, it’s clear to see that the Bureau of Foreign Trade (MOEA) from Taiwan, together with the Taiwan External Trade Development Council (TAITRA) and its foster companies, have taken this sentiment to heart.

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News • Subdermal quantum tattoo

Nano-patch stores medical information under the skin

Every year, a lack of vaccination leads to about 1.5 million preventable deaths, primarily in developing nations. One factor that makes vaccination campaigns in those nations more difficult is that there is little infrastructure for storing medical records, so there’s often no easy way to determine who needs a particular vaccine. Researchers at the Massachusetts Institute of Technology (MIT)…

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News • Lethal brain infection

How current treatment for fungal meningitis fuels drug resistance

A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns. Published in the journal mBio, the findings highlight the need to develop new drugs and treatment regimens for the lethal brain infection, which kills around 180,000 people each year. Cryptococcal…

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News • Non-alcoholic fatty liver disease

3D model of human liver tissue for better NAFLD diagnosis

Non-alcoholic fatty liver disease (NAFLD) is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of NAFLD. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural…

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News • Smart devices and more

New GE imaging tech and intelligent apps unveiled at RSNA

At RSNA 2019, GE Healthcare launches more than 30 new, imaging intelligent applications and smart devices designed to drive efficiency in radiology departments, aiming to double productivity and cost savings for systems by 2025. For healthcare executives, the new offerings help systems to save costs, improve technology utilization, and increase patient volumes. Clinicians also will benefit from…

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Article • Healthcare 2.0 by NVIDIA

Deploying AI in healthcare

With the right tools, physicians could transform the lives of patients and scientists. For Kimberly Powell, Vice President of Healthcare at NVIDIA, artificial intelligence is such a tool, and could meet the increasing demand for personalised medicine and next-generation clinics. ‘AI is the biggest technological breakthrough of our lifetime.’

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Sponsored • From the "Asian Silicon Valley"

Taiwan's R&D centers deliver continuous innovation in MedTech

From an initial focus on innovative manufacturing, in-house ICT technologies drove production efficiency and quality. Today, Taiwan has advanced to become a leader with its "Asian Silicon Valley" concept. The government also wants to further strengthen Taiwan's key position by independently developing medical products that meet the high demands of international markets – at…

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News • Monitoring bioresorbable magnesium

New insights on the corrosion of metal implants

Researchers in Zurich have recently been able to monitor the corrosion of bioresorbable magnesium alloys at the nanoscale over a time scale of a few seconds to many hours. This is an important step towards accurately predicting how fast implants are resorbed by the body to enable the development of tailored materials for temporary implant applications. Magnesium and its alloys are increasingly…

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News • Danger in the womb

Xenoestrogens in the womb: a burden for babies

Early childhood life in the womb is particularly sensitive to the effects of environmental pollutants. A team from Empa and the University of Vienna has now for the first time been able to show how a pollutant from contaminated food – the environmental estrogen zearalenone – spreads in the womb and is metabolized into harmful metabolites. Xenoestrogens are absorbed through the environment,…

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News • Multimillion research grant

One step closer to the artificial womb

The realization of an artificial womb has come one step closer, thanks to a new €2.9 million grant from the EU program Horizon 2020 for researchers in Eindhoven. The goal of the artificial womb is to increase the chances of survival for extremely premature babies outside the body. Just one year ago, the artificial womb was presented as a first design during the Dutch Design Week. This grant…

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Article • UK tests high-speed remote medical diagnosis

Ultrasound scanning via a 5G network

To demonstrate advances in 5G connectivity for healthcare, a UK team has linked a paramedic in a simulated ambulance to a hospital-based clinician. The paramedic wore a robotic or ‘haptic’ glove, which received signals over the live 5G network. Using a joystick, the clinician remotely directed the paramedic to move the ultrasound sensor to where on the patient the clinician wanted to scan.…

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News • Interneurons

Epilepsy: When the function of "brake cells" is disrupted

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which researchers from Lisbon were also involved, points in this direction. The results are…

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News • Tiny biomaterials

On the way to safer nanomedicine

Tiny particles that can fight cancer or that can easily pass through any interface within our body are a great promise for medicine. But there is little knowledge thus far about what exactly will happen to nanoparticles within our tissues and whether or not they can cause disease by themselves. Within an international research consortium, Empa scientists have now developed guidelines that should…

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News • Macular degeneration as a biomarker

Eye scan shows diseases at an early stage

More and more people aged 50 and over are suffering from age-related vision disorders. According to the World Health Organization, in four out of five cases they could be avoided if they were diagnosed at an early stage. A European team of scientists, including the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, has now researched a new method that will enable doctors to better…

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Video • VR simulator "HIPS"

Hip joint implantation in virtual reality

Researchers from Chemnitz and Bremen are developing a virtual reality simulator for a particularly critical step in hip joint implantation. Each year, more than 200,000 people receive a prosthetic hip in Germany. The success of these operations has a major impact on the quality of life of those affected. However, the procedure is often difficult, particularly the step that involves the so-called…

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News • Watching the change

Predicting cancer risk with computational electrodynamics

Researchers from Northwestern University are using Argonne supercomputers to advance the development of an optical microscopy technique that can predict and quantify cancer risks at extremely early stages. The basic principle driving Allen Taflove’s computational electrodynamics research — which bears the potential to transform how we diagnose, and possibly treat, various forms of cancer —…

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News • IT Solutions

Siemens Healthineers shows the power of data in the lab at AACC 2019

At the 71st AACC Annual Scientific Meeting & Clinical Lab Expo, Siemens Healthineers features in Booth #1039 its innovative IT solutions to combat the laboratory’s staffing challenges, limited budgets, and the increasing complexity in sample management and testing. “We will be demonstrating the power of our broad IT offerings and how the data they deliver, and artificial intelligence, can…

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Video • Tailor-made

Artificial heart valves from silicone

Scientists at ETH Zürich and the South African company Strait Access Technologies are using 3D printing to produce custom-made artificial heart valves from silicone. This could help meet an ageing population’s growing demand for replacement heart valves. The human heart has four chambers, each equipped with a valve to ensure blood flow in one direction only. If any of the heart valves are…

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News • Collaboration

The virtual patient comes to the angio-suite

Siemens Healthineers and Mentice AB announced the collaboration to fully integrate Mentice’s VIST Virtual Patient into the Artis icono angiography system from Siemens Healthineers. The VIST Virtual Patient thus becomes a fully integrated simulation solution for the angio-suite. The global partnership between the two companies will allow interventional radiologists, neuroradiologists, and…

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News • Study

Half of Ebola outbreaks go undetected

Half of Ebola outbreaks have gone undetected since the virus was discovered in 1976, scientists at the University of Cambridge estimate. The new findings come amid rising concern about Ebola in the Democratic Republic of Congo, and highlight the need for improved detection and rapid response to avoid future epidemics.

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News • Virtual reality

VR spots navigation problems in early Alzheimer’s disease

Virtual reality (VR) can identify early Alzheimer’s disease more accurately than ‘gold standard’ cognitive tests currently in use, suggests new research from the University of Cambridge. The study highlights the potential of new technologies to help diagnose and monitor conditions such as Alzheimer’s disease, which affects more than 525,000 people in the UK. In 2014, Professor John…

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News • Computational medicine

Using virtual populations to create safer medical devices

The current innovation process for medical technologies risks stifling the development of new devices, a leading researcher has argued. Alejandro Frangi, Professor of Computational Medicine at the University of Leeds, says the present system was geared towards small, incremental changes to existing technology or the development of new technologies that work for ‘most’ people but are…

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Article • ECR 2019

The impact of 3D printing in radiology

With increased precision, speed of service and reduced cost, 3D printing presents an opportunity to transform traditional healthcare and its delivery, and radiology is at the center of this new technology. In the ECR 2019 Special Focus Session “The 3D printing lab from bench to bedside”, the speakers emphasized that 3D printing does not only enable a new and innovative way to display imaging,…

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News • Hormone administration

Contraceptive jewelry could be the future of family planning

Family planning for women might one day be as simple as putting on an earring. A report published recently in the Journal of Controlled Release describes a technique for administering contraceptive hormones through special backings on jewelry such as earrings, wristwatches, rings or necklaces. The contraceptive hormones are contained in patches applied to portions of the jewelry in contact with…

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News • X-ray crystallography

Seeing the unseeable life inside a virus

Researchers at Cardiff University have used x-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection. The new insight could help in the development of drugs and therapies for infections and further advance the exploitation of viruses for medical treatments. The first author of the study, Alex Baker from Cardiff University’s School of…

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News • Pediatric resuscitation

Blindfolded training could help doctors save young lives

In a simulation training study, pediatric team leaders who wore a blindfold improved their leadership skills ratings by 11% over the course of 3 resuscitation scenarios, versus 5% for non-blindfolded leaders. Published in Frontiers in Pediatrics, the findings demonstrate a promising tool for improving training and outcomes in pediatric resuscitation. “Our study suggests that blindfolding the…

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News • Endoscopy RFA

New tool opens doors for pancreatic cancer treatment

A significantly more effective, minimally invasive treatment for pancreatic tumors may be on the horizon, thanks to a new endoscopy tool created in the Penn State Department of Mechanical Engineering. On average, only about 20 percent of pancreatic cancer patients are eligible for a surgical removal of the tumor, which is currently the most-effective treatment option. The location of the pancreas…

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News • Drug research

Opioids: no effect without side effect

Through genetic changes to the opioid receptor in mice, pharmacologists at Jena University Hospital have succeeded in almost completely suppressing the development of opioid tolerance. The pain-relieving effect actually improved and continued even when the drug was administered for longer periods. However, adverse effects such as respiratory depression and constipation, as well as withdrawal…

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Sponsored • Equipment for Iraq

Fulfilling a promise to Mosul with point-of-care ultrasound

Mosul, Iraq’s second city, is slowly rebuilding its healthcare infrastructure after years of war and destruction. Dr Henryk Pich, a consultant anaesthetist and intensive care physician at the University of Dresden, Germany, visited the region soon after the fighting had ended, supported by the independent aid organisation CADUS. Moved by the makeshift treatment centres he witnessed in the…

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Interview • Between man and molecule

The hunt for genetic risk factors

Professor Christoph M Friedrich researches the interface between man and molecule. Born in Westphalia, Germany, the professor for biomedical computer science at Dortmund University of Applied Sciences recently took up an additional role at the Institute for Medical Informatics, Biometrics and Epidemiology (IMIBE) in Essen University Hospital. In 2013, the cooperation between the two institutions…

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News • Intracerebral hemorrhage

Can sudden weather change raise stroke risk?

A collaborative study led by a neurologist at Rush University Medical Center and an environmental scientist at the University of Illinois at Chicago suggests that weather patterns that cause dramatic changes in barometric pressure may increase the incidence of a type of stroke known as spontaneous intracerebral hemorrhage, that is, the rupture of a blood vessel in the brain. The researchers…

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News • Future healthcare

AI in radiology: beyond imaging

Today, artificial intelligence (AI) can be found everywhere: in our cars, our smartphones and even our working environments. AI has many areas of application, including in the healthcare sector. AI will change the interaction between doctors and patients, but most patients won’t even know it’s involved. That’s because improving the patient experience, helping to increase productivity,…

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Video • Fighting cancer

'Zapping' tumors might be the future of radiation therapy

New accelerator-based technology being developed by the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University aims to reduce the side effects of cancer radiation therapy by shrinking its duration from minutes to under a second. Built into future compact medical devices, technology developed for high-energy physics could also help make radiation therapy more…

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News • Emerging Tech

Will 3D printing bring radiology to the next level?

As 3D printing technology continues to evolve, read how radiology will be involved in managing digital workflow related to patient care. “3D printing is a part of medicine, and radiology is at the center of this impactful new technology,” said RSNA 3D Printing Special Interest Group (SIG) Chair Jane Matsumoto, MD, assistant professor of radiology and co-director of the 3D Printing Lab at the…

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Article • Innovation

AI helpers simplify clinical MRI scans

The new 1.5 Tesla MRI from Siemens Healthineers, Magnetom Sola, is packed with helpful algorithms and other functions. AI-supported systems monitor patients and scan parameters and ensure consistent image quality. Whilst visitors at this year’s ECR-Expo admired the new device, Prof. Ulrike Attenberger has already tested it in practice.

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Article • Cut device-related pressure ulcers

Biomedical designers must increase safety

Whilst acknowledging that state-of-the-art bioengineering approaches are being applied in preventing Medical Device Related Pressure Ulcers (MDRPUs), Professor Amit Gefen, from the Department of Biomedical Engineering at Tel Aviv University, believes there are gaps in knowledge and technology in this area and therefore more must be done to improve patient care and avoid additional healthcare…

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Article • Neurosurgical operating theatre

Neurosurgery taught via Virtual Reality

Virtual Reality (VR) technology is aiding trainee surgeons to practise complex procedures in a simulated setting, rather than learning skills on real patients. VR is also helping to demystify neurosurgery in that it enables medical students and patients to ‘enter’ and experience a neurosurgical operating theatre. Alex Alamri, a trainee neurosurgeon at Barts Health NHS Trust in London, UK,…

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Article • Surgical interventions

Technology and team spirit to ensure future talent

The number of surgical interventions in Germany over the last ten years has increased by around 30%, but it would be wrong to talk of a heyday – mainly due to a lack of young talent, says Prof. Dr. Jörg Fuchs. The president of the German Society of Surgery (DGCH) and director of the Clinic and Polyclinic for Paediatric Surgery and Paediatric Urology at Tübingen University Hospital talks about…

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News • Innovation award

Multi-organ "lab-on-a-chip" to reduce animal testing

To simulate the blood circulation and the organs of animals or humans, engineers from Fraunhofer in Dresden have developed a so-called "multi-organ chip". This microsystem from the Fraunhofer Institute for Material and Beam Technology IWS Dresden has now received an "EARTO Innovation Award" in Brussels. The "lab-on-a-chip" will help industry to develop new drugs and…

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Article • A link to the past

Tomorrow's hospitals – inspired by 15th century architechture

In the hustle and bustle of the Salone del Mobile – Milan’s famous design week – an oasis of peace and calm comes as a surprise. The Cortile dei Bagni is such a surprise; this inner bath courtyard is part of a Milan hospital built in the 15th century. Here, architect Filippo Taidelli installed a contemplative space experience that tells a story about the future of healthcare. Its title…

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Article • 3D & CHD

The changing face of imaging in cardiology

While the question is still debated as to whether MRI is the better CT, along comes a potential game changer – a new data based 3-D reconstruction method of heart anatomy and function that aims to replace diagnostic coronary angiography. In the near future not only adult patients with coronary heart disease could benefit from this new technique but also children with complex congenital heart…

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News • Reinforced learning

AI masters tightrope walk of cancer treatment dosage

Using a new approach called 'reinforced learning', researchers have taught an artificial intelligence (AI) to responsibly choose the right amount of chemo- and radiotherapy for glioblastoma patients. The technique, which is insprired by behavioural psychology, has given the AI the ability to master the tightrope walk between effective tumor shrinkage and the medications' severe side effects.

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News • Interventional radiology in oncology

Augmented reality sees right through the patient

A new augmented reality system to guide procedures in interventional oncology is currently taking its first steps. A three-step experiment proves this system to be precise and reliable enough to facilitate image guidance critical to the success of interventional oncology procedures. Using a back-face camera and a tablet PC to visualise the patient, the system projects 3D images of body structures…

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News • Matrix-forming proteins

Experimental targeted therapy might prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers at the Cincinnati Children’s Heart Institute report in the journal Circulation testing a manufactured peptide called pUR4 to block the fibronectin protein in human…

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News • Long-term caffeine

There's a catch to your daily coffee intake, study finds

A study coordinated by the Institute of Neuroscience of the Universitat Autònoma de Barcelona (Inc-UAB) and in collaboration with the Karolinska Institutet (KI) in Sweden provides evidence that a long-term consumption of caffeine has negative effects for Alzheimer’s disease, worsening the neuropsychiatric symptoms appearing in the majority of those affected by the disorder. The research was…

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Article • Regulation

Implementing MDR is complex and expensive and holds little reality

By 2020 medical devices manufacturers must document the clinical effectiveness of their devices more extensively. The Medical Device Regulation (MDR) presents a fundamental impact on innovation and price calculation for medical devices. Since the faulty PIP breast implants scandal in France (March 2010), there have been frequent calls for tighter licensing regulations for medical devices within…

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News • Advances in manufacturing

Easy printing of biosensors made of graphene

Cell-based biosensors can simulate the effect of various substances, such as drugs, on the human body in the laboratory. Depending on the measuring principle, though, producing them can be expensive. As a result, they are often not used. Cost factors for sensors that perform measurements electrically are the expensive electrode material and complex production. Fraunhofer scientists are now…

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Article • The InnerEye Project

AI drives analysis of medical images

Some time in the distant future artificial intelligence (AI) systems may displace radiologists and many other medical specialists. However, in a far more realistic future AI tools will assist radiologists by performing very complex functions with medical imaging data that are impossible or unfeasible today, according to a presentation at the RSNA/AAPM Symposium during the Radiological Society of…

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Article • An era of turbulence and innovation

The birth and rebirth of imaging

The New Horizons Lecture at the RSNA annual meeting is a keynote address that looks to the future, and the inventor of a major innovation in magnetic resonance imaging (MRI) technology, Daniel K Sodickson MD PhD, did just that. His lecture entitled ‘A New Light: The Birth and Rebirth of Imaging’ looked back at how MRI has evolved and forward at what it will become.

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News • A map to the heart

The meaning of heart geometry in surgery

Geometry is often referenced for matters of the heart. Marriage has been described as “two parallel lines,” and others have compared love to an “irrational equation” or as unending as “pi.” But when it comes to the medical matters of the heart, geometry can be a lonely and dangerous affair. “The shape and size of a heart is not the same for every person, and a diseased heart, such…

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Video • Automation in radiology

Machine learning techniques generate clinical labels of medical scans

Researchers used machine learning techniques, including natural language processing algorithms, to identify clinical concepts in radiologist reports for CT scans, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published in the journal Radiology. The technology is an important first step in the development of artificial intelligence that could interpret scans and…

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News • Infection research

Designer nanoparticles destroy a broad array of viruses

Viral infections kill millions of people worldwide every year, but currently available antiviral drugs are limited in that they mostly act against one or a small handful of related viruses. A few broad-spectrum drugs that prevent viral entry into healthy cells exist, but they usually need to be taken continuously to prevent infection, and resistance through viral mutation is a serious risk. Now,…

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News • Simulated CNS

This ‘brain-on-a-chip” could be a new medical testing ground

Lawrence Livermore National Laboratory scientists and engineers have developed a “brain-on-a-chip” device aimed at testing and predicting the effects of biological and chemical agents, disease, or pharmaceutical drugs on the brain over time without the need for human or animal subjects. The device, part of the Lab’s iCHIP (in-vitro Chip-Based Human Investigational Platform) project,…

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